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Gene: FTO (FTO alpha-ketoglutarate dependent dioxygenase) Canis lupus familiaris
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Symbol: FTO
Name: FTO alpha-ketoglutarate dependent dioxygenase
RGD ID: 12296192
Description: ENCODES a protein that exhibits dioxygenase activity (inferred); DNA-N1-methyladenine dioxygenase activity (inferred); ferrous iron binding (inferred); INVOLVED IN DNA demethylation (ortholog); oxidative demethylation (ortholog); ASSOCIATED WITH Body Weight (ortholog); Breast Neoplasms (ortholog); Growth Retardation, Developmental Delay, Coarse Facies, and Early Death (ortholog); FOUND IN nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: alpha-ketoglutarate-dependent dioxygenase FTO; FTO, alpha-ketoglutarate dependent dioxygenase; m6A(m)-demethylase FTO; mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; mRNA N(6)-methyladenosine demethylase FTO; tRNA N1-methyl adenine demethylase FTO; U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO
Orthologs:
Homo sapiens (human) : FTO (FTO alpha-ketoglutarate dependent dioxygenase)  HGNC  Alliance
Mus musculus (house mouse) : Fto (fat mass and obesity associated)  MGI  Alliance
Rattus norvegicus (Norway rat) : Fto (FTO, alpha-ketoglutarate dependent dioxygenase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fto (FTO alpha-ketoglutarate dependent dioxygenase)
Pan paniscus (bonobo/pygmy chimpanzee) : FTO (FTO alpha-ketoglutarate dependent dioxygenase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fto (FTO alpha-ketoglutarate dependent dioxygenase)
Sus scrofa (pig) : FTO (FTO alpha-ketoglutarate dependent dioxygenase)
Chlorocebus sabaeus (African green monkey) : FTO (FTO alpha-ketoglutarate dependent dioxygenase)
Heterocephalus glaber (naked mole-rat) : Fto (FTO alpha-ketoglutarate dependent dioxygenase)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl261,652,236 - 62,080,059 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1261,699,864 - 62,080,199 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - uncurated

Genomics

Comparative Map Data

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
 
More on FTO
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 12296192
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.