GRHL1 (grainyhead like transcription factor 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: GRHL1 (grainyhead like transcription factor 1) Canis lupus familiaris
Analyze
Symbol: GRHL1
Name: grainyhead like transcription factor 1
RGD ID: 12292951
Description: ENCODES a protein that exhibits chromatin DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor binding (ortholog); INVOLVED IN desmosome organization (ortholog); epidermis development (ortholog); establishment of skin barrier (ortholog); FOUND IN intracellular membrane-bounded organelle (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: grainyhead-like 1; grainyhead-like protein 1 homolog
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1176,953,945 - 7,007,175 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl176,953,836 - 7,006,134 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha176,882,122 - 6,934,414 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0177,053,267 - 7,105,654 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl177,052,104 - 7,105,639 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1176,945,283 - 6,997,603 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0176,947,411 - 6,999,812 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0176,961,516 - 7,013,871 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
GRHL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1176,953,945 - 7,007,175 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl176,953,836 - 7,006,134 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha176,882,122 - 6,934,414 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0177,053,267 - 7,105,654 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl177,052,104 - 7,105,639 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1176,945,283 - 6,997,603 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0176,947,411 - 6,999,812 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0176,961,516 - 7,013,871 (+)NCBIUU_Cfam_GSD_1.0
GRHL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3829,951,693 - 10,002,277 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl29,951,693 - 10,002,277 (+)EnsemblGRCh38hg38GRCh38
GRCh37210,091,822 - 10,142,405 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36210,009,273 - 10,059,856 (+)NCBINCBI36Build 36hg18NCBI36
Celera210,007,717 - 10,058,329 (+)NCBICelera
Cytogenetic Map2p25.1NCBI
HuRef29,942,567 - 9,993,653 (+)NCBIHuRef
CHM1_1210,021,441 - 10,071,878 (+)NCBICHM1_1
T2T-CHM13v2.029,979,623 - 10,030,385 (+)NCBIT2T-CHM13v2.0
Grhl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391224,622,234 - 24,667,390 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1224,622,282 - 24,667,390 (+)EnsemblGRCm39 Ensembl
GRCm381224,572,232 - 24,617,391 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1224,572,283 - 24,617,391 (+)EnsemblGRCm38mm10GRCm38
MGSCv371225,257,152 - 25,302,256 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361225,169,798 - 25,206,467 (+)NCBIMGSCv36mm8
Celera1226,034,221 - 26,079,315 (+)NCBICelera
Cytogenetic Map12A1.3NCBI
cM Map128.49NCBI
Grhl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8646,935,947 - 46,986,126 (+)NCBIGRCr8
mRatBN7.2641,207,325 - 41,257,516 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl641,207,348 - 41,254,301 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0643,734,837 - 43,795,757 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl643,743,702 - 43,794,342 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0660,602,932 - 60,668,616 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4642,217,279 - 42,260,621 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1642,132,033 - 42,263,747 (+)NCBI
Celera640,494,932 - 40,542,079 (+)NCBICelera
Cytogenetic Map6q16NCBI
Grhl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554875,407,128 - 5,433,113 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554875,407,187 - 5,432,828 (+)NCBIChiLan1.0ChiLan1.0
GRHL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v212116,522,037 - 116,572,161 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A116,526,008 - 116,576,125 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A9,944,385 - 9,994,510 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A10,108,150 - 10,155,177 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A10,105,486 - 10,155,177 (+)Ensemblpanpan1.1panPan2
Grhl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629251,444,414 - 51,492,247 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365326,199,453 - 6,247,295 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365326,199,525 - 6,247,282 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GRHL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3126,463,387 - 126,511,321 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13126,462,946 - 126,511,185 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23135,019,617 - 135,028,744 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GRHL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11497,632,494 - 97,686,257 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604514,630,186 - 14,681,247 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Grhl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248655,046,147 - 5,078,492 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248655,046,030 - 5,078,545 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in GRHL1
385 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005630111 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005630112 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038453383 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038453384 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038498218 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038498219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038560754 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038560755 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038624784 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038624785 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038690689 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038690690 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_532872 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002614967 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000196 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000359 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCAFT00000005454   ⟹   ENSCAFP00000005053
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl176,958,337 - 7,006,134 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000045268   ⟹   ENSCAFP00000035846
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl176,953,836 - 7,006,134 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845045340   ⟹   ENSCAFP00845035560
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl177,052,104 - 7,105,639 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845045500   ⟹   ENSCAFP00845035690
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl177,062,145 - 7,105,639 (+)Ensembl
RefSeq Acc Id: XM_038453383   ⟹   XP_038309311
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha176,882,122 - 6,934,414 (+)NCBI
RefSeq Acc Id: XM_038453384   ⟹   XP_038309312
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha176,882,122 - 6,934,414 (+)NCBI
RefSeq Acc Id: XM_038498218   ⟹   XP_038354146
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1176,945,283 - 6,997,603 (+)NCBI
RefSeq Acc Id: XM_038498219   ⟹   XP_038354147
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1176,945,283 - 6,997,603 (+)NCBI
RefSeq Acc Id: XM_038560754   ⟹   XP_038416682
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0176,961,516 - 7,013,871 (+)NCBI
RefSeq Acc Id: XM_038560755   ⟹   XP_038416683
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0176,961,516 - 7,013,871 (+)NCBI
RefSeq Acc Id: XM_038624784   ⟹   XP_038480712
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0176,947,411 - 6,999,812 (+)NCBI
RefSeq Acc Id: XM_038624785   ⟹   XP_038480713
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0176,947,411 - 6,999,812 (+)NCBI
RefSeq Acc Id: XM_038690689   ⟹   XP_038546617
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0177,053,267 - 7,105,654 (+)NCBI
RefSeq Acc Id: XM_038690690   ⟹   XP_038546618
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0177,053,267 - 7,105,654 (+)NCBI
Ensembl Acc Id: ENSCAFP00000005053   ⟸   ENSCAFT00000005454
Ensembl Acc Id: ENSCAFP00000035846   ⟸   ENSCAFT00000045268
RefSeq Acc Id: XP_038354146   ⟸   XM_038498218
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038354147   ⟸   XM_038498219
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038480712   ⟸   XM_038624784
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038480713   ⟸   XM_038624785
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038546617   ⟸   XM_038690689
- Peptide Label: isoform X1
- UniProtKB: A0A8C0QH88 (UniProtKB/TrEMBL),   A0A8P0S961 (UniProtKB/TrEMBL),   A0A8C0R8N0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038546618   ⟸   XM_038690690
- Peptide Label: isoform X2
- UniProtKB: A0A8C0R8N0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038309311   ⟸   XM_038453383
- Peptide Label: isoform X1
- UniProtKB: A0A8C0QH88 (UniProtKB/TrEMBL),   A0A8P0S961 (UniProtKB/TrEMBL),   A0A8C0R8N0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038309312   ⟸   XM_038453384
- Peptide Label: isoform X2
- UniProtKB: A0A8C0R8N0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038416682   ⟸   XM_038560754
- Peptide Label: isoform X1
- UniProtKB: A0A8C0QH88 (UniProtKB/TrEMBL),   A0A8C0R8N0 (UniProtKB/TrEMBL),   A0A8P0S961 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038416683   ⟸   XM_038560755
- Peptide Label: isoform X2
- UniProtKB: A0A8C0R8N0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845035690   ⟸   ENSCAFT00845045500
Ensembl Acc Id: ENSCAFP00845035560   ⟸   ENSCAFT00845045340
Protein Domains
Grh/CP2 DB

Promoters
RGD ID:13686159
Promoter ID:EPDNEW_C4227
Type:single initiation site
Name:GRHL1_1
Description:grainyhead like transcription factor 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1176,957,796 - 6,957,856EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000003394 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030005213 UniProtKB/TrEMBL
  ENSCAFG00040006717 UniProtKB/TrEMBL
  ENSCAFG00845025614 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000005454.6 UniProtKB/TrEMBL
  ENSCAFT00000045268.3 UniProtKB/TrEMBL
  ENSCAFT00030009784.1 UniProtKB/TrEMBL
  ENSCAFT00030009867.1 UniProtKB/TrEMBL
  ENSCAFT00030009953.1 UniProtKB/TrEMBL
  ENSCAFT00040012581.1 UniProtKB/TrEMBL
  ENSCAFT00040012635.1 UniProtKB/TrEMBL
  ENSCAFT00845045340.1 UniProtKB/TrEMBL
  ENSCAFT00845045500.1 UniProtKB/TrEMBL
InterPro CP2 UniProtKB/TrEMBL
  TF_CP2-like UniProtKB/TrEMBL
NCBI Gene GRHL1 ENTREZGENE
PANTHER GRAINYHEAD-LIKE PROTEIN 1 HOMOLOG UniProtKB/TrEMBL
  TRANSCRIPTION FACTOR CP2 UniProtKB/TrEMBL
Pfam CP2 UniProtKB/TrEMBL
PROSITE GRH_CP2_DB UniProtKB/TrEMBL
UniProt A0A8C0ML50_CANLF UniProtKB/TrEMBL
  A0A8C0QH88 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0QHD9_CANLF UniProtKB/TrEMBL
  A0A8C0R8N0 ENTREZGENE
  A0A8I3PWF9_CANLF UniProtKB/TrEMBL
  A0A8I3S9K1_CANLF UniProtKB/TrEMBL
  A0A8P0S961 ENTREZGENE
UniProt Secondary A0A8P0S961 UniProtKB/TrEMBL
VGNC ID VGNC:41476 ENTREZGENE