MPC1 (mitochondrial pyruvate carrier 1) - Rat Genome Database

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Gene: MPC1 (mitochondrial pyruvate carrier 1) Canis lupus familiaris
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Symbol: MPC1
Name: mitochondrial pyruvate carrier 1
RGD ID: 12292200
Description: ENCODES a protein that exhibits pyruvate transmembrane transporter activity (ortholog); INVOLVED IN acetyl-CoA biosynthetic process from pyruvate (ortholog); cellular response to leukemia inhibitory factor (ortholog); mitochondrial pyruvate transmembrane transport (ortholog); PARTICIPATES IN citric acid cycle pathway; fructose-1,6-bisphosphatase deficiency pathway; fumaric aciduria pathway; ASSOCIATED WITH Fraser syndrome 3 (ortholog); genetic disease (ortholog); mitochondrial pyruvate carrier deficiency (ortholog); FOUND IN mitochondrial inner membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: brain protein 44-like; BRP44L
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1154,379,195 - 54,395,697 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha155,167,961 - 55,184,449 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0154,557,931 - 54,574,673 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl154,557,928 - 54,574,770 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1154,455,224 - 54,471,730 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0154,304,263 - 54,320,827 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0154,928,921 - 54,945,422 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
MPC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1154,379,195 - 54,395,697 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha155,167,961 - 55,184,449 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0154,557,931 - 54,574,673 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl154,557,928 - 54,574,770 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1154,455,224 - 54,471,730 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0154,304,263 - 54,320,827 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0154,928,921 - 54,945,422 (-)NCBIUU_Cfam_GSD_1.0
MPC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386166,364,919 - 166,382,940 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6166,364,919 - 166,383,013 (-)EnsemblGRCh38hg38GRCh38
GRCh376166,778,407 - 166,796,428 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366166,698,397 - 166,716,476 (-)NCBINCBI36Build 36hg18NCBI36
Build 346166,748,820 - 166,766,897NCBI
Celera6167,517,772 - 167,535,855 (-)NCBICelera
Cytogenetic Map6q27NCBI
HuRef6164,249,365 - 164,267,463 (-)NCBIHuRef
CHM1_16167,042,136 - 167,060,235 (-)NCBICHM1_1
T2T-CHM13v2.06167,741,850 - 167,759,859 (-)NCBIT2T-CHM13v2.0
Mpc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39178,502,590 - 8,516,499 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl178,501,736 - 8,516,493 (+)EnsemblGRCm39 Ensembl
GRCm38178,283,787 - 8,297,667 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl178,282,904 - 8,297,661 (+)EnsemblGRCm38mm10GRCm38
MGSCv37178,476,678 - 8,490,526 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36178,121,987 - 8,135,835 (+)NCBIMGSCv36mm8
Celera12112,049,395 - 112,049,996 (-)NCBICelera
Cytogenetic Map17A1NCBI
cM Map174.92NCBI
Mpc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8154,985,305 - 54,996,979 (-)NCBIGRCr8
mRatBN7.2152,437,745 - 52,449,399 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl152,437,741 - 52,449,400 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx153,139,229 - 53,150,880 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0159,130,934 - 59,142,585 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0153,214,825 - 53,226,476 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0153,026,608 - 53,038,229 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl153,026,608 - 53,038,229 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0154,275,046 - 54,286,667 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4147,077,723 - 47,089,344 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1147,080,667 - 47,092,289 (-)NCBI
Celera148,200,723 - 48,212,344 (-)NCBICelera
Cytogenetic Map1q12NCBI
Mpc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543915,516,090 - 15,531,116 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543915,515,966 - 15,531,618 (+)NCBIChiLan1.0ChiLan1.0
MPC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25186,572,971 - 186,591,196 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16184,468,871 - 184,487,160 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06164,331,604 - 164,349,747 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16169,313,271 - 169,318,685 (-)NCBIpanpan1.1PanPan1.1panPan2
Mpc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946148,927,328 - 148,929,837 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648916,179,810 - 16,184,020 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648916,179,321 - 16,181,991 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MPC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.112,541,475 - 2,552,864 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213,681,075 - 3,692,480 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MPC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11394,080,417 - 94,100,149 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604065,907,418 - 65,927,150 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mpc1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478512,877,077 - 12,891,914 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478512,876,942 - 12,892,417 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in MPC1
273 total Variants

Expression


Sequence


RefSeq Acc Id: ENSCAFT00845008454   ⟹   ENSCAFP00845006660
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl154,557,928 - 54,574,569 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845008457   ⟹   ENSCAFP00845006662
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl154,558,076 - 54,574,770 (-)Ensembl
RefSeq Acc Id: XM_005615567   ⟹   XP_005615624
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1154,379,195 - 54,395,697 (-)NCBI
Dog10K_Boxer_Tasha155,167,961 - 55,184,449 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038465844   ⟹   XP_038321772
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1154,455,224 - 54,471,730 (-)NCBI
RefSeq Acc Id: XM_038465845   ⟹   XP_038321773
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1154,455,224 - 54,467,424 (-)NCBI
RefSeq Acc Id: XM_038526524   ⟹   XP_038382452
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0154,928,921 - 54,945,422 (-)NCBI
RefSeq Acc Id: XM_038526525   ⟹   XP_038382453
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0154,928,921 - 54,941,103 (-)NCBI
RefSeq Acc Id: XM_038590814   ⟹   XP_038446742
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0154,304,263 - 54,320,827 (-)NCBI
RefSeq Acc Id: XM_038590815   ⟹   XP_038446743
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0154,304,263 - 54,316,445 (-)NCBI
RefSeq Acc Id: XM_038654612   ⟹   XP_038510540
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0154,557,931 - 54,574,673 (-)NCBI
RefSeq Acc Id: XM_038654613   ⟹   XP_038510541
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0154,557,931 - 54,570,366 (-)NCBI
RefSeq Acc Id: XP_005615624   ⟸   XM_005615567
- Peptide Label: isoform X2
- UniProtKB: A0A8C0MJ98 (UniProtKB/TrEMBL),   A0A8I3MTX7 (UniProtKB/TrEMBL),   A0A8C0R1Q0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_038321772   ⟸   XM_038465844
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038321773   ⟸   XM_038465845
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038446742   ⟸   XM_038590814
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038446743   ⟸   XM_038590815
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038510540   ⟸   XM_038654612
- Peptide Label: isoform X2
- UniProtKB: A0A8C0MJ98 (UniProtKB/TrEMBL),   A0A8I3MTX7 (UniProtKB/TrEMBL),   A0A8C0R1Q0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038510541   ⟸   XM_038654613
- Peptide Label: isoform X1
- UniProtKB: A0A8C0PUA8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038382452   ⟸   XM_038526524
- Peptide Label: isoform X2
- UniProtKB: A0A8C0MJ98 (UniProtKB/TrEMBL),   A0A8C0R1Q0 (UniProtKB/TrEMBL),   A0A8I3MTX7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038382453   ⟸   XM_038526525
- Peptide Label: isoform X1
- UniProtKB: A0A8C0PUA8 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845006660   ⟸   ENSCAFT00845008454
RefSeq Acc Id: ENSCAFP00845006662   ⟸   ENSCAFT00845008457


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000041860 UniProtKB/TrEMBL
  ENSCAFG00030007812 UniProtKB/TrEMBL
  ENSCAFG00040001427 UniProtKB/TrEMBL
  ENSCAFG00845004722 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000060297.2 UniProtKB/TrEMBL
  ENSCAFT00000089865.2 UniProtKB/TrEMBL
  ENSCAFT00030014381.1 UniProtKB/TrEMBL
  ENSCAFT00030014439.1 UniProtKB/TrEMBL
  ENSCAFT00040002703.1 UniProtKB/TrEMBL
  ENSCAFT00040002713.1 UniProtKB/TrEMBL
  ENSCAFT00040002717.1 UniProtKB/TrEMBL
  ENSCAFT00845008454 ENTREZGENE
  ENSCAFT00845008454.1 UniProtKB/TrEMBL
  ENSCAFT00845008457.1 UniProtKB/TrEMBL
InterPro MPC UniProtKB/TrEMBL
NCBI Gene MPC1 ENTREZGENE
PANTHER MITOCHONDRIAL PYRUVATE CARRIER 1 UniProtKB/TrEMBL
  UPF0041 BRAIN PROTEIN 44-RELATED UniProtKB/TrEMBL
Pfam MPC UniProtKB/TrEMBL
UniProt A0A8C0MJ98 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0MMF6_CANLF UniProtKB/TrEMBL
  A0A8C0PQ60_CANLF UniProtKB/TrEMBL
  A0A8C0PUA8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0R1Q0 ENTREZGENE
  A0A8I3MTX7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3N9M2_CANLF UniProtKB/TrEMBL