UCK1 (uridine-cytidine kinase 1) - Rat Genome Database

Name: UCK1
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: UCK1 (uridine-cytidine kinase 1) Canis lupus familiaris

Analyze

Symbol:

UCK1

Name:

uridine-cytidine kinase 1

RGD ID:

12288795

Description:

ENCODES a protein that exhibits ATP binding (inferred); uridine kinase activity (inferred); INVOLVED IN CTP salvage (inferred); phosphorylation (inferred); UMP salvage (inferred); ASSOCIATED WITH Ehlers-Danlos syndrome classic type 1 (ortholog); nerve compression syndrome (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Also known as:

LOW QUALITY PROTEIN: uridine-cytidine kinase 1

RGD Orthologs

Human

Mouse

Rat

Chinchilla

Bonobo

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	UCK1 (uridine-cytidine kinase 1)	HGNC	HomoloGene, NCBI
Mus musculus (house mouse):	Uck1 (uridine-cytidine kinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Uck1 (uridine-cytidine kinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Uck1 (uridine-cytidine kinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	UCK1 (uridine-cytidine kinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Uck1 (uridine-cytidine kinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	UCK1 (uridine-cytidine kinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):	UCK1 (uridine-cytidine kinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Uck1 (uridine-cytidine kinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	9	52,609,313 - 52,614,622 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	9	52,609,972 - 52,615,655 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Ehlers-Danlos syndrome classic type 1 (ISO)

nerve compression syndrome (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

CTP salvage (IEA)

phosphorylation (IEA)

UMP salvage (IEA)

Cellular Component

cytoplasm (IBA)

cytosol (IBA)

Molecular Function

ATP binding (IEA)

protein binding (ISO)

uridine kinase activity (IEA)

References

Genomics

Comparative Map Data

UCK1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	9	52,609,313 - 52,614,622 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	9	52,609,972 - 52,615,655 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

UCK1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	9	131,523,801 - 131,531,264 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	9	131,523,801 - 131,531,263 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	9	134,399,188 - 134,406,650 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
GRCh37	9	134,399,183 - 134,406,662 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	133,389,012 - 133,396,476 (-)	NCBI	NCBI36		hg18	NCBI36
Build 34	9	131,428,744 - 131,436,209	NCBI
Celera	9	104,939,363 - 104,946,841 (-)	NCBI
Cytogenetic Map	9	q34.13	NCBI
HuRef	9	103,893,800 - 103,901,279 (-)	NCBI		HuRef
CHM1_1	9	134,548,581 - 134,556,053 (-)	NCBI		CHM1_1

Uck1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	32,145,014 - 32,150,117 (-)	NCBI	GRCm39		mm39
GRCm38	2	32,255,002 - 32,260,105 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	32,255,002 - 32,260,159 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	32,110,522 - 32,115,625 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	2	32,077,011 - 32,082,070 (-)	NCBI			mm8
Celera	2	31,959,332 - 31,964,435 (-)	NCBI		Celera
Cytogenetic Map	2	B	NCBI

Uck1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	3	15,538,580 - 15,544,465 (-)	NCBI
Rnor_6.0 Ensembl	3	11,271,885 - 11,277,757 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	3	11,271,874 - 11,277,757 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	3	16,620,744 - 16,626,627 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	11,366,634 - 11,372,517 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	3	11,264,015 - 11,268,800 (-)	NCBI
Celera	3	10,283,446 - 10,289,273 (-)	NCBI		Celera
Cytogenetic Map	3	p12	NCBI

Uck1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955513	1,203,934 - 1,208,724 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955513	1,203,934 - 1,208,720 (-)	NCBI	ChiLan1.0	ChiLan1.0

UCK1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	9	131,285,877 - 131,293,338 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	131,285,877 - 131,293,338 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	9	102,646,056 - 102,653,525 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

Uck1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936487	18,267,878 - 18,271,406 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

UCK1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	271,448,364 - 271,453,816 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	271,448,362 - 271,453,811 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	305,456,743 - 305,462,182 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

UCK1
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	6,612,306 - 6,634,326 (+)	NCBI
ChlSab1.1 Ensembl	12	6,612,378 - 6,618,968 (+)	Ensembl

Uck1
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624760	4,490,118 - 4,494,707 (+)	NCBI

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	reproductive system	respiratory system	adipose tissue
High
Medium	5	5	18	2	6	2	6	6	12	8	10	6
Low			4	4		4
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_038487108	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038548985	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038548986	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038548987	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038612936	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038612937	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038612938	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038616804	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038616811	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038616820	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038678243	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038678244	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038678245	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000095	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000103	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000313	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSCAFT00000031666 ⟹ ENSCAFP00000029480

RefSeq Status:

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	9	52,609,928 - 52,614,622 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00000078011 ⟹ ENSCAFP00000045401

RefSeq Status:

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	9	52,609,313 - 52,612,461 (+)	Ensembl

RefSeq Acc Id:

XM_022423937 ⟹ XP_022279645

RefSeq Status:

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	9	52,609,972 - 52,615,655 (+)	NCBI

Sequence:

show sequence

CGGGCGGAGCCCGGGATGGCTTCGGCTGGAGGACGGGACTGCGAGGCTGCGGCTCCAGATGCGG
ACCGCCCTCACTAGCGGTCCTTCCAGATCGGGGTGAGCTGCGGCACCGCCNNNNNNNNNNTGAT
AGGGGTGAGCGAAGGCACCGCGAGCGGGAAGTCCACCGTGTGCGAGAAGATCATGGAGCTGCTG
GGCCAGAACGAAGTGGACCACCGGCAGCGGAAGCTGGTCATCCTGAGTCAAGACAGGTTCTACA
AGGTCCTGACCCCAGAACAGAAGGCCAAGGCGTTGAAGGGACAGTACAATTTCGACCACCCAGA
TGCCTTTGATAATGACTTGATGCACAGGACTCTGAAGAACATCGTGGAGGGCAAAACAGTCGAG
GTCCCAACCTACGATTTTGTGACCCATTCAAGGTTAGCGGAGACCACAGTGGTGTACCCTGCAG
ATGTGGTCCTGTTCGAGGGCATCTTGGTGTTCTACAGCCAGGAGGTCCGGGACATGTTTCACCT
GCGCCTCTTCGTGGACACGGACTCCGACGTCAGGCTGTCGAGAAGAGTTCTCCGGGATGTGCAC
CGCGGGAGGGACCTGGAGCAGATCCTGACCCAGTACACCACCTTCGTCAAGCCAGCCTTCGAAG
AGTTCTGCCTGCCGGTACCCCTCTCGCTTACTTGGGGAGCTTCCTTTTCTCACTTTTCAAGAGG
ACTCTTGGCGCCCTGTCCTGTGAGCGCTGAATTACGGGTGAACAGGGTCTGGCACCTCTGCCCG
GTGGGGCTCTTTGCGCTCTGCATGCCCCCTCAGGATGGGGCAGAGCCCAAGCGCGCCTGGCCTG
GAGGGCCCAACGGGGAGCGGATGTGGCTAAGCGTGCTTGTCTTTGCTACAGTGGCCATCAACCT
GATCGTGCAGCACATCCAGGACATCCTGAGCGGCGACATCTGCAAGTGGCACCGAGGGTCCAAT
GGGCGGAGCTACAAGAGGACCTTCCCTGAGCCCGGAGACCGCCCTGGGGTGCTGACCTCTGGCA
AGCGATCGCACTTGGAGTCCAGCAGCAGACCCCACTGAGGAACCCCGATAGACCATGCTCAGGG
TCTGGCCCACCCGCCCCATAGACGCTGCCGCTGCTTCTTCTCGGCGTCATACGGTACAGACAGG
GTGGTGCGAGGATCACAGGGTCCTCCCTGATGCGGGCAGACCTCCCGTTCCTCATGCTTGGCGG
GATGTTGGCAGGCCCCCCGTTTTCACCTGCTTCCTCACGTTAAGGCGGTTAAAAGTCTGAGTTA
CTGGGAAATGCCACAGAATGTGTGCTGAGCCTGTCACGCCTCTTGGGGACATGGGGCACAAGCC
TGCACACTGTGGCTGTCCTGGCGTGTGTGACACCAACCCAGAGCAAGAGAGATTCTAGCATGAT
CTGGTTCCCACACGTGACTGAAGCAGAGGTTTGAAGAGAGAGTACGTCATGTCTCCCTCCCCCC
TTGTTACACGTGCGAATGTTTCGTTATTTACCGTGTTAGTTGTGACCTAGTAACCGAGTTTCGT
GCCCCACCAGCGGGTGTGATCCAGTGTGGCACACACTGACGGAAGGAGCTACAGGAGCTTTCCT
TCCTCCCGGGCTGTGCGCCAAGGCAGGAGCCAAGGAAGGAGCCCCGGGAAACAAGCTCTCCTTA
ACCAGCATCAGACGCGGGAGGCAGCACCTGCTCCCTCAAGCAGGGCGGGACGCAGGCTGCTGGG
TGCCGTGTCCACACACAGGCCTCCTCAGGCGTCCGGGGCTGGGGGGGCTGTGTGGACAGGGCTT
CGCTGGGGTAGCCTGGGCCCATCCGGGGCATGCCGTCCAAAGCCAGCTGGCCTCCTTGCACACG
CCAAGTCCATAGCTGCACGAACGGTGCCTGCGGTCTGCGTTGTCCTGGTTTGTCTCCCTCCCAG
ACGGCACTGTATGAAAGTGACACTTTCCTGTTGCCCCCCGGCCAACCTGCATGGGCGATCCTGG
TTTCCTTCTATCGAGTACTAAGTGTAGTTACACAGATAGGACCTCAGTTGAGTTTGGCCGAGCT
CTGTGCCCTCTTGGAGAGCGTATCAATAAATAACATCAAACACCGGT

hide sequence

Protein Sequences


Protein RefSeqs	XP_038343036	(Get FASTA)	NCBI Sequence Viewer
	XP_038404913	(Get FASTA)	NCBI Sequence Viewer
	XP_038404914	(Get FASTA)	NCBI Sequence Viewer
	XP_038404915	(Get FASTA)	NCBI Sequence Viewer
	XP_038468864	(Get FASTA)	NCBI Sequence Viewer
	XP_038468865	(Get FASTA)	NCBI Sequence Viewer
	XP_038468866	(Get FASTA)	NCBI Sequence Viewer
	XP_038472732	(Get FASTA)	NCBI Sequence Viewer
	XP_038472739	(Get FASTA)	NCBI Sequence Viewer
	XP_038472748	(Get FASTA)	NCBI Sequence Viewer
	XP_038534171	(Get FASTA)	NCBI Sequence Viewer
	XP_038534172	(Get FASTA)	NCBI Sequence Viewer
	XP_038534173	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

XP_022279645 ⟸ XM_022423937

- Sequence:

show sequence

MASAGGRDCEAAAPDADRPHXRSFQIGVSCGTAXXXXIGVSEGTASGKSTVCEKIMELLGQNEV
DHRQRKLVILSQDRFYKVLTPEQKAKALKGQYNFDHPDAFDNDLMHRTLKNIVEGKTVEVPTYD
FVTHSRLAETTVVYPADVVLFEGILVFYSQEVRDMFHLRLFVDTDSDVRLSRRVLRDVHRGRDL
EQILTQYTTFVKPAFEEFCLPVPLSLTWGASFSHFSRGLLAPCPVSAELRVNRVWHLCPVGLFA
LCMPPQDGAEPKRAWPGGPNGERMWLSVLVFATVAINLIVQHIQDILSGDICKWHRGSNGRSYK
RTFPEPGDRPGVLTSGKRSHLESSSRPH

hide sequence

RefSeq Acc Id:

ENSCAFP00000045401 ⟸ ENSCAFT00000078011

RefSeq Acc Id:

ENSCAFP00000029480 ⟸ ENSCAFT00000031666

Protein Domains

PRK

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000019903	Ensembl, UniProtKB/TrEMBL
Ensembl Protein	ENSCAFP00000029480	UniProtKB/TrEMBL
	ENSCAFP00000045401	UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000031666	UniProtKB/TrEMBL
	ENSCAFT00000078011	UniProtKB/TrEMBL
InterPro	P-loop_NTPase	UniProtKB/TrEMBL
	PRK/URK	UniProtKB/TrEMBL
	UCK-1	UniProtKB/TrEMBL
	Uridine_kinase-like	UniProtKB/TrEMBL
NCBI Gene	UCK1	ENTREZGENE
PANTHER	PTHR10285:SF66	UniProtKB/TrEMBL
Pfam	PRK	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52540	UniProtKB/TrEMBL
UniProt	A0A5F4BU79_CANLF	UniProtKB/TrEMBL
	F1PH93_CANLF	UniProtKB/TrEMBL
VGNC ID	VGNC:58343	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar