CRNN (cornulin) - Rat Genome Database

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Gene: CRNN (cornulin) Canis lupus familiaris
Analyze
Symbol: CRNN
Name: cornulin
RGD ID: 12286940
Description: ENCODES a protein that exhibits calcium ion binding (inferred); calcium-dependent protein binding (inferred); metal ion binding (inferred); INVOLVED IN cell-cell adhesion (ortholog); positive regulation of keratinocyte proliferation (ortholog); regulation of gene expression (ortholog); ASSOCIATED WITH gastrointestinal stromal tumor (ortholog); genetic disease (ortholog); immunodeficiency 42 (ortholog); FOUND IN membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11761,380,706 - 61,386,294 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1761,380,706 - 61,386,504 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1760,840,017 - 60,845,597 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01762,407,268 - 62,412,848 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11761,233,298 - 61,238,877 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01761,327,675 - 61,331,601 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01762,054,619 - 62,060,199 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CRNN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11761,380,706 - 61,386,294 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1761,380,706 - 61,386,504 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1760,840,017 - 60,845,597 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01762,407,268 - 62,412,848 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11761,233,298 - 61,238,877 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01761,327,675 - 61,331,601 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01762,054,619 - 62,060,199 (-)NCBIUU_Cfam_GSD_1.0
CRNN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381152,409,243 - 152,414,263 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1152,409,243 - 152,414,263 (-)EnsemblGRCh38hg38GRCh38
GRCh371152,381,719 - 152,386,739 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361150,648,343 - 150,653,352 (-)NCBINCBI36Build 36hg18NCBI36
Build 341149,194,791 - 149,199,801NCBI
Celera1125,492,515 - 125,497,547 (-)NCBICelera
Cytogenetic Map1q21.3NCBI
HuRef1123,755,264 - 123,760,295 (-)NCBIHuRef
CHM1_11153,777,068 - 153,782,100 (-)NCBICHM1_1
T2T-CHM13v2.01151,545,792 - 151,550,812 (-)NCBIT2T-CHM13v2.0
Crnn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39393,052,096 - 93,057,125 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl393,052,094 - 93,057,126 (+)EnsemblGRCm39 Ensembl
GRCm38393,144,789 - 93,149,818 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl393,144,787 - 93,149,819 (+)EnsemblGRCm38mm10GRCm38
MGSCv37392,948,709 - 92,953,393 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36393,230,190 - 93,234,874 (+)NCBIMGSCv36mm8
MGSCv36393,859,775 - 93,864,459 (+)NCBIMGSCv36mm8
Celera393,928,821 - 93,933,495 (-)NCBICelera
Cytogenetic Map3F2.1NCBI
cM Map340.14NCBI
Crnn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82181,427,384 - 181,432,142 (+)NCBIGRCr8
mRatBN7.22178,733,329 - 178,736,404 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2178,731,796 - 178,736,216 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.02193,427,097 - 193,432,070 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2193,429,176 - 193,431,487 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02211,438,738 - 211,441,049 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42186,149,368 - 186,151,679 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12186,099,473 - 186,101,785 (+)NCBI
Celera2171,521,128 - 171,526,101 (-)NCBICelera
Cytogenetic Map2q34NCBI
Crnn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495558947,531 - 77,458 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495558947,743 - 75,383 (+)NCBIChiLan1.0ChiLan1.0
CRNN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2197,437,247 - 97,443,129 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1197,188,342 - 97,194,222 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01127,743,094 - 127,748,737 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11131,377,596 - 131,382,626 (-)NCBIpanpan1.1PanPan1.1panPan2
Crnn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505823,484,401 - 23,487,188 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365802,513,644 - 2,517,221 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CRNN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl496,933,287 - 96,939,662 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1496,933,221 - 96,938,980 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24105,929,623 - 105,935,333 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CRNN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12011,280,298 - 11,285,906 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603810,772,390 - 10,775,555 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in CRNN
71 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system endocrine system integumental system nervous system reproductive system
High
Medium 6
Low
Below cutoff 1 1 2 8

Sequence


RefSeq Acc Id: ENSCAFT00000020640   ⟹   ENSCAFP00000019157
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1761,380,706 - 61,384,322 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000049818   ⟹   ENSCAFP00000042146
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1761,380,706 - 61,386,504 (-)Ensembl
RefSeq Acc Id: XM_022405018   ⟹   XP_022260726
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11761,380,706 - 61,386,294 (-)NCBI
Dog10K_Boxer_Tasha1760,840,017 - 60,845,597 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038499924   ⟹   XP_038355852
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11761,233,298 - 61,238,877 (-)NCBI
RefSeq Acc Id: XM_038560620   ⟹   XP_038416548
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01762,054,619 - 62,060,199 (-)NCBI
RefSeq Acc Id: XM_038624647   ⟹   XP_038480575
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01761,327,675 - 61,331,601 (-)NCBI
RefSeq Acc Id: XM_038690551   ⟹   XP_038546479
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01762,407,268 - 62,412,848 (-)NCBI
RefSeq Acc Id: XP_022260726   ⟸   XM_022405018
- Peptide Label: isoform X1
- UniProtKB: A0A8I3PMZ1 (UniProtKB/TrEMBL),   A0A8P0SVN6 (UniProtKB/TrEMBL),   A0A8C0K6A8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000042146   ⟸   ENSCAFT00000049818
RefSeq Acc Id: ENSCAFP00000019157   ⟸   ENSCAFT00000020640
RefSeq Acc Id: XP_038355852   ⟸   XM_038499924
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038480575   ⟸   XM_038624647
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038546479   ⟸   XM_038690551
- Peptide Label: isoform X1
- UniProtKB: A0A8I3PMZ1 (UniProtKB/TrEMBL),   A0A8P0SVN6 (UniProtKB/TrEMBL),   A0A8C0K6A8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038416548   ⟸   XM_038560620
- Peptide Label: isoform X1
- UniProtKB: A0A8C0K6A8 (UniProtKB/TrEMBL),   A0A8I3PMZ1 (UniProtKB/TrEMBL),   A0A8P0SVN6 (UniProtKB/TrEMBL)
Protein Domains
EF-hand


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000013000 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00040011884 UniProtKB/TrEMBL
  ENSCAFG00845025948 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000049818.3 UniProtKB/TrEMBL
  ENSCAFT00040021893.1 UniProtKB/TrEMBL
  ENSCAFT00845045784 ENTREZGENE
  ENSCAFT00845045784.1 UniProtKB/TrEMBL
Gene3D-CATH EF-hand UniProtKB/TrEMBL
InterPro EF-hand-dom_pair UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/TrEMBL
  S-100_dom UniProtKB/TrEMBL
  S100_Ca-bd_sub UniProtKB/TrEMBL
NCBI Gene CRNN ENTREZGENE
PANTHER PTHR11639:SF26 UniProtKB/TrEMBL
  S100 CALCIUM-BINDING PROTEIN UniProtKB/TrEMBL
Pfam S_100 UniProtKB/TrEMBL
PROSITE EF_HAND_1 UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/TrEMBL
SMART S_100 UniProtKB/TrEMBL
Superfamily-SCOP SSF47473 UniProtKB/TrEMBL
UniProt A0A8C0K6A8 ENTREZGENE
  A0A8C0SCS1_CANLF UniProtKB/TrEMBL
  A0A8I3PMZ1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0SVN6 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:39626 ENTREZGENE