GLRX2 (glutaredoxin 2) - Rat Genome Database
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Gene: GLRX2 (glutaredoxin 2) Canis lupus familiaris
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Symbol: GLRX2
Name: glutaredoxin 2
RGD ID: 12285051
Description: ENCODES a protein that exhibits protein disulfide oxidoreductase activity (inferred); INVOLVED IN aging (ortholog); cellular response to superoxide (ortholog); ASSOCIATED WITH Hyperparathyroidism 1 (ortholog); FOUND IN dendrite (ortholog); intracellular membrane-bounded organelle (ortholog); mitochondrial matrix (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: glutaredoxin-2, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl385,964,039 - 5,971,676 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1385,963,800 - 5,971,673 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
GLRX2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl385,964,039 - 5,971,676 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1385,963,800 - 5,971,673 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
GLRX2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1193,090,866 - 193,106,114 (-)EnsemblGRCh38hg38GRCh38
GRCh381193,096,465 - 193,106,114 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371193,065,595 - 193,075,659 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361191,332,223 - 191,341,867 (-)NCBINCBI36hg18NCBI36
Build 341189,797,256 - 189,806,213NCBI
Celera1166,175,205 - 166,184,851 (-)NCBI
Cytogenetic Map1q31.2NCBI
HuRef1164,301,400 - 164,311,051 (-)NCBIHuRef
CHM1_11194,487,507 - 194,497,577 (-)NCBICHM1_1
Glrx2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391143,614,787 - 143,625,416 (+)NCBIGRCm39mm39
GRCm381143,739,224 - 143,749,678 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1143,716,338 - 143,749,676 (+)EnsemblGRCm38mm10GRCm38
MGSCv371145,586,479 - 145,596,808 (+)NCBIGRCm37mm9NCBIm37
MGSCv361145,501,567 - 145,511,896 (+)NCBImm8
Celera1146,314,372 - 146,324,701 (+)NCBICelera
Cytogenetic Map1FNCBI
cM Map162.53NCBI
Glrx2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01360,529,057 - 60,552,115 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1360,529,932 - 60,537,916 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01365,517,621 - 65,540,676 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41357,567,017 - 57,589,873 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11357,581,096 - 57,603,951 (+)NCBI
Celera1355,569,577 - 55,592,422 (+)NCBICelera
Cytogenetic Map13q21NCBI
Glrx2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540630,497,562 - 30,509,340 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540630,497,562 - 30,506,463 (-)NCBIChiLan1.0ChiLan1.0
GLRX2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11172,848,858 - 172,859,970 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1172,849,013 - 172,859,062 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01168,555,858 - 168,565,949 (-)NCBIMhudiblu_PPA_v0panPan3
Glrx2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049366381,325,076 - 1,333,994 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GLRX2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.110679,305 - 689,890 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
GLRX2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12536,318,894 - 36,328,567 (+)NCBI
ChlSab1.1 Ensembl2536,319,637 - 36,328,417 (+)Ensembl
Glrx2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624814481,981 - 505,052 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 5 22 6 6 6 6 6 12 8 10 6
Low
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003434301 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005640811 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022415449 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038448377 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038448378 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038448379 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038448380 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038448381 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038448382 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038463916 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038463917 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038522293 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038522294 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038522295 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038522296 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038522297 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038522298 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038586098 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038586099 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038586100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038586101 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038586102 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038586103 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038650501 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038650502 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038650503 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038650504 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038650505 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038650506 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_536114 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000038 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000360 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000087 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000370 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000038 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000016757   ⟹   ENSCAFP00000015507
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl385,964,754 - 5,971,535 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000084787   ⟹   ENSCAFP00000063372
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl385,964,039 - 5,971,676 (+)Ensembl
RefSeq Acc Id: XM_003434301   ⟹   XP_003434349
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1385,965,023 - 5,971,673 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005640811   ⟹   XP_005640868
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1385,964,745 - 5,971,673 (+)NCBI
Sequence:
RefSeq Acc Id: XM_022415449   ⟹   XP_022271157
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1385,964,082 - 5,971,673 (+)NCBI
Sequence:
RefSeq Acc Id: XM_536114   ⟹   XP_536114
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1385,963,800 - 5,971,673 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003434349 (Get FASTA)   NCBI Sequence Viewer  
  XP_005640868 (Get FASTA)   NCBI Sequence Viewer  
  XP_022271157 (Get FASTA)   NCBI Sequence Viewer  
  XP_038304305 (Get FASTA)   NCBI Sequence Viewer  
  XP_038304306 (Get FASTA)   NCBI Sequence Viewer  
  XP_038304307 (Get FASTA)   NCBI Sequence Viewer  
  XP_038304308 (Get FASTA)   NCBI Sequence Viewer  
  XP_038304309 (Get FASTA)   NCBI Sequence Viewer  
  XP_038304310 (Get FASTA)   NCBI Sequence Viewer  
  XP_038319844 (Get FASTA)   NCBI Sequence Viewer  
  XP_038319845 (Get FASTA)   NCBI Sequence Viewer  
  XP_038378221 (Get FASTA)   NCBI Sequence Viewer  
  XP_038378222 (Get FASTA)   NCBI Sequence Viewer  
  XP_038378223 (Get FASTA)   NCBI Sequence Viewer  
  XP_038378224 (Get FASTA)   NCBI Sequence Viewer  
  XP_038378225 (Get FASTA)   NCBI Sequence Viewer  
  XP_038378226 (Get FASTA)   NCBI Sequence Viewer  
  XP_038442026 (Get FASTA)   NCBI Sequence Viewer  
  XP_038442027 (Get FASTA)   NCBI Sequence Viewer  
  XP_038442028 (Get FASTA)   NCBI Sequence Viewer  
  XP_038442029 (Get FASTA)   NCBI Sequence Viewer  
  XP_038442030 (Get FASTA)   NCBI Sequence Viewer  
  XP_038442031 (Get FASTA)   NCBI Sequence Viewer  
  XP_038506429 (Get FASTA)   NCBI Sequence Viewer  
  XP_038506430 (Get FASTA)   NCBI Sequence Viewer  
  XP_038506431 (Get FASTA)   NCBI Sequence Viewer  
  XP_038506432 (Get FASTA)   NCBI Sequence Viewer  
  XP_038506433 (Get FASTA)   NCBI Sequence Viewer  
  XP_038506434 (Get FASTA)   NCBI Sequence Viewer  
  XP_536114 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_536114   ⟸   XM_536114
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_005640868   ⟸   XM_005640811
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_003434349   ⟸   XM_003434301
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_022271157   ⟸   XM_022415449
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSCAFP00000063372   ⟸   ENSCAFT00000084787
RefSeq Acc Id: ENSCAFP00000015507   ⟸   ENSCAFT00000016757
Protein Domains
Glutaredoxin

Promoters
RGD ID:13689188
Promoter ID:EPDNEW_C7257
Type:single initiation site
Name:GLRX2_1
Description:glutaredoxin 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1385,964,750 - 5,964,810EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000010549 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00000015507 UniProtKB/TrEMBL
  ENSCAFP00000063372 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000016757 UniProtKB/TrEMBL
  ENSCAFT00000084787 UniProtKB/TrEMBL
Gene3D-CATH 3.40.30.10 UniProtKB/TrEMBL
InterPro Glutaredoxin UniProtKB/TrEMBL
  Glutaredoxin_euk/vir UniProtKB/TrEMBL
  Glutaredoxin_subgr UniProtKB/TrEMBL
  Thioredoxin-like_sf UniProtKB/TrEMBL
NCBI Gene GLRX2 ENTREZGENE
Pfam Glutaredoxin UniProtKB/TrEMBL
PRINTS GLUTAREDOXIN UniProtKB/TrEMBL
PROSITE GLUTAREDOXIN_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF52833 UniProtKB/TrEMBL
TIGRFAMs GRX_euk UniProtKB/TrEMBL
UniProt A0A5F4D9F8_CANLF UniProtKB/TrEMBL
  F1PUT1_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:41274 ENTREZGENE