CREG2 (cellular repressor of E1A stimulated genes 2) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: CREG2 (cellular repressor of E1A stimulated genes 2) Canis lupus familiaris
Analyze
Symbol: CREG2
Name: cellular repressor of E1A stimulated genes 2
RGD ID: 12282927
Description: ASSOCIATED WITH genetic disease (ortholog); FOUND IN endoplasmic reticulum (inferred); extracellular region (inferred); extracellular space (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: protein CREG2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11041,540,829 - 41,576,549 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1041,540,826 - 41,572,005 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1041,465,911 - 41,501,834 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01042,408,511 - 42,444,575 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1042,408,511 - 42,440,034 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11042,121,462 - 42,157,368 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01042,403,969 - 42,439,877 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01042,595,365 - 42,631,294 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

Genomics

Comparative Map Data
CREG2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11041,540,829 - 41,576,549 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1041,540,826 - 41,572,005 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1041,465,911 - 41,501,834 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01042,408,511 - 42,444,575 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1042,408,511 - 42,440,034 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11042,121,462 - 42,157,368 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01042,403,969 - 42,439,877 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01042,595,365 - 42,631,294 (+)NCBIUU_Cfam_GSD_1.0
CREG2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382101,345,550 - 101,387,503 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2101,345,550 - 101,387,503 (-)EnsemblGRCh38hg38GRCh38
GRCh372101,962,012 - 102,003,965 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362101,331,655 - 101,370,489 (-)NCBINCBI36Build 36hg18NCBI36
Build 342101,423,742 - 101,462,575NCBI
Celera296,168,703 - 96,207,615 (-)NCBICelera
Cytogenetic Map2q11.2NCBI
HuRef295,728,993 - 95,767,814 (-)NCBIHuRef
CHM1_12101,969,227 - 102,008,038 (-)NCBICHM1_1
T2T-CHM13v2.02101,804,250 - 101,846,207 (-)NCBIT2T-CHM13v2.0
Creg2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39139,657,574 - 39,690,350 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl139,657,574 - 39,690,642 (-)EnsemblGRCm39 Ensembl
GRCm38139,618,406 - 39,652,052 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl139,618,406 - 39,651,474 (-)EnsemblGRCm38mm10GRCm38
MGSCv37139,675,251 - 39,708,027 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36139,562,952 - 39,595,728 (-)NCBIMGSCv36mm8
Celera139,415,441 - 39,449,617 (-)NCBICelera
Cytogenetic Map1BNCBI
cM Map118.37NCBI
Creg2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8949,367,693 - 49,441,133 (-)NCBIGRCr8
mRatBN7.2941,872,000 - 41,945,413 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl941,902,304 - 41,945,095 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0946,328,088 - 46,402,237 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl946,360,061 - 46,401,911 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0946,047,373 - 46,089,231 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4938,698,544 - 38,830,140 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera939,648,511 - 39,694,478 (-)NCBICelera
Cytogenetic Map9q22NCBI
Creg2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554707,094,483 - 7,115,792 (-)NCBIChiLan1.0ChiLan1.0
CREG2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21226,838,764 - 26,887,390 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A26,841,498 - 26,890,151 (+)NCBINHGRI_mPanPan1
PanPan1.12A102,324,445 - 102,363,730 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A102,324,445 - 102,363,735 (-)Ensemblpanpan1.1panPan2
Creg2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629290,949,580 - 90,988,356 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936713149,678 - 183,459 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936713147,571 - 183,150 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CREG2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl352,918,844 - 52,977,924 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1352,918,475 - 52,978,020 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2355,464,877 - 55,523,176 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CREG2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1145,048,996 - 5,088,993 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl145,050,356 - 5,088,668 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041172,715,652 - 172,763,089 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Creg2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247496,036,755 - 6,064,714 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247496,032,034 - 6,064,769 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CREG2
553 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 6
Low 4 13 1 6 8 9 1
Below cutoff 1 5 9 6 6 6 5 6 1 5

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000048501   ⟹   ENSCAFP00000038399
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1041,540,826 - 41,572,005 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845022471   ⟹   ENSCAFP00845017647
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1042,408,511 - 42,440,034 (+)Ensembl
RefSeq Acc Id: XM_003639339   ⟹   XP_003639387
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11041,540,829 - 41,576,549 (+)NCBI
Dog10K_Boxer_Tasha1041,465,911 - 41,501,834 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038488998   ⟹   XP_038344926
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11042,121,462 - 42,157,368 (+)NCBI
RefSeq Acc Id: XM_038550984   ⟹   XP_038406912
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01042,595,365 - 42,631,294 (+)NCBI
RefSeq Acc Id: XM_038614889   ⟹   XP_038470817
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01042,403,969 - 42,439,877 (+)NCBI
RefSeq Acc Id: XM_038680267   ⟹   XP_038536195
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01042,408,511 - 42,444,575 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_003639387   ⟸   XM_003639339
- UniProtKB: A0A8C0SLE9 (UniProtKB/TrEMBL),   A0A8P0ST77 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000038399   ⟸   ENSCAFT00000048501
RefSeq Acc Id: XP_038344926   ⟸   XM_038488998
RefSeq Acc Id: XP_038470817   ⟸   XM_038614889
RefSeq Acc Id: XP_038536195   ⟸   XM_038680267
- UniProtKB: A0A8I3RX49 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038406912   ⟸   XM_038550984
RefSeq Acc Id: ENSCAFP00845017647   ⟸   ENSCAFT00845022471

Promoters
RGD ID:13685025
Promoter ID:EPDNEW_C3094
Type:multiple initiation site
Name:CREG2_1
Description:cellular repressor of E1A stimulated genes 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11041,540,872 - 41,540,932EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000030846 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030016218 UniProtKB/TrEMBL
  ENSCAFG00040013947 UniProtKB/TrEMBL
  ENSCAFG00845012626 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000048501.4 UniProtKB/TrEMBL
  ENSCAFT00030029894.1 UniProtKB/TrEMBL
  ENSCAFT00040025743.1 UniProtKB/TrEMBL
  ENSCAFT00845022471 ENTREZGENE
  ENSCAFT00845022471.1 UniProtKB/TrEMBL
InterPro CREG UniProtKB/TrEMBL
  Split_barrel_FMN-bd UniProtKB/TrEMBL
NCBI Gene CREG2 ENTREZGENE
PANTHER CREG1 PROTEIN UniProtKB/TrEMBL
  PROTEIN CREG2 UniProtKB/TrEMBL
Pfam Pyrid_oxidase_2 UniProtKB/TrEMBL
PIRSF CREG UniProtKB/TrEMBL
Superfamily-SCOP FMN-binding split barrel UniProtKB/TrEMBL
UniProt A0A8C0SLE9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3RX49 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0ST77 ENTREZGENE
UniProt Secondary A0A8P0ST77 UniProtKB/TrEMBL
VGNC ID VGNC:39606 ENTREZGENE