FEV (FEV transcription factor, ETS family member) - Rat Genome Database

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Gene: FEV (FEV transcription factor, ETS family member) Canis lupus familiaris
Analyze
Symbol: FEV
Name: FEV transcription factor, ETS family member
RGD ID: 12277974
Description: ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity (ortholog); double-stranded DNA binding (ortholog); INVOLVED IN maternal behavior (ortholog); neuron fate specification (ortholog); neuron maturation (ortholog); ASSOCIATED WITH alacrima, achalasia, and impaired intellectual development syndrome (ortholog); autism spectrum disorder (ortholog); cerebrotendinous xanthomatosis (ortholog); FOUND IN nuclear speck (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: FEV (ETS oncogene family); FEV, ETS transcription factor
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13725,548,578 - 25,552,092 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3726,367,854 - 26,372,353 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03725,563,091 - 25,567,596 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3725,563,099 - 25,568,000 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13725,467,675 - 25,472,180 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03725,402,725 - 25,407,296 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03725,423,527 - 25,428,026 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nuclear speck  (IEA)
nucleus  (IEA)

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
FEV
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13725,548,578 - 25,552,092 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3726,367,854 - 26,372,353 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03725,563,091 - 25,567,596 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3725,563,099 - 25,568,000 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13725,467,675 - 25,472,180 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03725,402,725 - 25,407,296 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03725,423,527 - 25,428,026 (-)NCBIUU_Cfam_GSD_1.0
FEV
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382218,981,087 - 218,985,184 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2218,981,087 - 218,985,184 (-)EnsemblGRCh38hg38GRCh38
GRCh372219,845,809 - 219,849,906 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362219,554,053 - 219,558,623 (-)NCBINCBI36Build 36hg18NCBI36
Build 342219,671,313 - 219,675,884NCBI
Celera2213,615,522 - 213,620,092 (-)NCBICelera
Cytogenetic Map2q35NCBI
HuRef2211,699,837 - 211,704,406 (-)NCBIHuRef
CHM1_12219,853,266 - 219,857,836 (-)NCBICHM1_1
T2T-CHM13v2.02219,469,462 - 219,473,559 (-)NCBIT2T-CHM13v2.0
Fev
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39174,920,660 - 74,924,632 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl174,920,668 - 74,924,578 (-)EnsemblGRCm39 Ensembl
GRCm38174,881,501 - 74,885,473 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl174,881,509 - 74,885,419 (-)EnsemblGRCm38mm10GRCm38
MGSCv37174,928,083 - 74,931,982 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36174,814,716 - 74,818,626 (-)NCBIMGSCv36mm8
Celera175,436,582 - 75,440,470 (-)NCBICelera
Cytogenetic Map1C4NCBI
Fev
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8983,887,844 - 83,891,718 (-)NCBIGRCr8
mRatBN7.2976,439,164 - 76,443,603 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl976,439,172 - 76,443,065 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx984,884,303 - 84,888,174 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0990,013,255 - 90,017,126 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0988,399,404 - 88,403,275 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0982,142,981 - 82,146,855 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl982,142,981 - 82,146,874 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0981,911,561 - 81,915,435 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4974,214,764 - 74,218,638 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1974,361,745 - 74,365,639 (-)NCBI
Celera974,010,770 - 74,014,644 (-)NCBICelera
Cytogenetic Map9q33NCBI
Fev
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545314,449,352 - 14,452,663 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545314,449,352 - 14,453,145 (+)NCBIChiLan1.0ChiLan1.0
FEV
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213121,611,786 - 121,616,374 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B121,626,750 - 121,631,339 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B106,238,933 - 106,243,499 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B224,832,403 - 224,838,813 (-)NCBIpanpan1.1PanPan1.1panPan2
Fev
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303175,059,167 - 175,062,546 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365691,402,513 - 1,406,067 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365691,402,513 - 1,408,699 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FEV
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15121,004,665 - 121,009,014 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115121,005,279 - 121,008,748 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
FEV
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110104,879,790 - 104,886,722 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10104,880,347 - 104,883,916 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604094,509,000 - 94,513,765 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fev
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248236,032,352 - 6,036,211 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248236,032,188 - 6,036,211 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in FEV
25 total Variants

Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00845050440   ⟹   ENSCAFP00845039546
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3725,563,099 - 25,568,000 (-)Ensembl
RefSeq Acc Id: XM_038447351   ⟹   XP_038303279
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.03725,563,091 - 25,567,596 (-)NCBI
RefSeq Acc Id: XM_038463859   ⟹   XP_038319787
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha3726,367,854 - 26,372,353 (-)NCBI
RefSeq Acc Id: XM_038522101   ⟹   XP_038378029
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.13725,467,675 - 25,472,180 (-)NCBI
RefSeq Acc Id: XM_038585115   ⟹   XP_038441043
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.03725,423,527 - 25,428,026 (-)NCBI
RefSeq Acc Id: XM_038649525   ⟹   XP_038505453
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.03725,402,725 - 25,407,296 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_038378029   ⟸   XM_038522101
RefSeq Acc Id: XP_038505453   ⟸   XM_038649525
RefSeq Acc Id: XP_038303279   ⟸   XM_038447351
- UniProtKB: A0A8C0MK31 (UniProtKB/TrEMBL),   A0A8I3Q119 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038319787   ⟸   XM_038463859
- UniProtKB: A0A8C0LTK0 (UniProtKB/TrEMBL),   A0A8P0PE30 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038441043   ⟸   XM_038585115
- UniProtKB: A0A8C0LTK0 (UniProtKB/TrEMBL),   A0A8P0PE30 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845039546   ⟸   ENSCAFT00845050440
Protein Domains
ETS


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000041791 UniProtKB/TrEMBL
  ENSCAFG00030008097 UniProtKB/TrEMBL
  ENSCAFG00040023967 UniProtKB/TrEMBL
  ENSCAFG00845028578 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000071273.2 UniProtKB/TrEMBL
  ENSCAFT00000095318.1 UniProtKB/TrEMBL
  ENSCAFT00030014873.1 UniProtKB/TrEMBL
  ENSCAFT00030014928.1 UniProtKB/TrEMBL
  ENSCAFT00040044651.1 UniProtKB/TrEMBL
  ENSCAFT00845050440 ENTREZGENE
  ENSCAFT00845050440.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/TrEMBL
InterPro Ets_dom UniProtKB/TrEMBL
  ETS_fam UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
NCBI Gene FEV ENTREZGENE
PANTHER PROTEIN FEV UniProtKB/TrEMBL
  PTHR11849 UniProtKB/TrEMBL
Pfam Ets UniProtKB/TrEMBL
PRINTS ETSDOMAIN UniProtKB/TrEMBL
PROSITE ETS_DOMAIN_1 UniProtKB/TrEMBL
  ETS_DOMAIN_2 UniProtKB/TrEMBL
  ETS_DOMAIN_3 UniProtKB/TrEMBL
SMART ETS UniProtKB/TrEMBL
Superfamily-SCOP SSF46785 UniProtKB/TrEMBL
UniProt A0A8C0LTK0 ENTREZGENE
  A0A8C0MK31 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0RF87_CANLF UniProtKB/TrEMBL
  A0A8I3Q119 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0PE30 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0PJW8_CANLF UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-01-29 FEV  FEV transcription factor, ETS family member    FEV, ETS transcription factor  Symbol and/or name change 5135510 APPROVED