SAG (S-antigen visual arrestin) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: SAG (S-antigen visual arrestin) Canis lupus familiaris
Analyze
Symbol: SAG
Name: S-antigen visual arrestin
RGD ID: 12277207
Description: ENCODES a protein that exhibits spectrin binding (ortholog); INVOLVED IN G protein-coupled receptor internalization (inferred); signal transduction (inferred); PARTICIPATES IN altered visual phototransduction pathway; retinitis pigmentosa pathway; visual phototransduction pathway; ASSOCIATED WITH hereditary night blindness; cone dystrophy (ortholog); congenital stationary night blindness (ortholog); FOUND IN photoreceptor inner segment (ortholog); photoreceptor outer segment (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 48 kDa protein; ARR; arrestin, S-antigen; retina and pineal gland (arrestin); retinal S-antigen; rod photoreceptor arrestin; S-AG; S-antigen; S-arrestin; sag1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12544,800,141 - 44,843,580 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2544,812,362 - 44,843,579 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2545,307,685 - 45,338,815 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02545,060,350 - 45,103,430 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2545,072,284 - 45,103,429 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12544,996,643 - 45,027,722 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02544,842,616 - 44,873,724 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02544,997,874 - 45,029,086 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:9088745   PMID:12123530   PMID:22301074   PMID:24019744   PMID:30032202  


Genomics

Comparative Map Data
SAG
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12544,800,141 - 44,843,580 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2544,812,362 - 44,843,579 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2545,307,685 - 45,338,815 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02545,060,350 - 45,103,430 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2545,072,284 - 45,103,429 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12544,996,643 - 45,027,722 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02544,842,616 - 44,873,724 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02544,997,874 - 45,029,086 (+)NCBIUU_Cfam_GSD_1.0
SAG
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382233,307,816 - 233,347,055 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2233,307,816 - 233,347,055 (+)EnsemblGRCh38hg38GRCh38
GRCh372234,216,462 - 234,255,701 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362233,881,207 - 233,920,440 (+)NCBINCBI36Build 36hg18NCBI36
Build 342233,998,492 - 234,037,701NCBI
Celera2227,937,838 - 227,977,217 (+)NCBICelera
Cytogenetic Map2q37.1NCBI
HuRef2226,017,093 - 226,056,496 (+)NCBIHuRef
CHM1_12234,222,389 - 234,261,775 (+)NCBICHM1_1
T2T-CHM13v2.02233,795,900 - 233,835,144 (+)NCBIT2T-CHM13v2.0
Sag
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39187,731,402 - 87,772,880 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl187,731,402 - 87,772,880 (+)EnsemblGRCm39 Ensembl
GRCm38187,798,143 - 87,845,158 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl187,803,680 - 87,845,158 (+)EnsemblGRCm38mm10GRCm38
MGSCv37189,700,255 - 89,741,732 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36189,634,851 - 89,676,328 (+)NCBIMGSCv36mm8
Celera190,761,584 - 90,803,003 (+)NCBICelera
Cytogenetic Map1DNCBI
cM Map144.44NCBI
Sag
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8995,915,640 - 95,956,641 (+)NCBIGRCr8
mRatBN7.2988,467,797 - 88,508,821 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl988,469,376 - 88,508,820 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx996,893,929 - 96,933,394 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09102,030,109 - 102,069,572 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.09100,397,588 - 100,437,033 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0994,926,901 - 94,972,162 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl994,928,489 - 94,972,027 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0994,646,333 - 94,691,522 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4986,759,933 - 86,799,902 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1986,944,774 - 86,983,310 (+)NCBI
Celera254,322,671 - 54,345,084 (-)NCBICelera
Celera985,877,786 - 85,890,904 (+)NCBICelera
Cytogenetic Map9q35NCBI
Sag
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554532,844,925 - 2,878,846 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554532,845,561 - 2,878,342 (-)NCBIChiLan1.0ChiLan1.0
SAG
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213135,910,867 - 135,948,833 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B135,925,831 - 135,963,742 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B120,532,049 - 120,574,914 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B239,449,910 - 239,487,626 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B239,449,910 - 239,487,537 (+)Ensemblpanpan1.1panPan2
Sag
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303186,974,069 - 187,007,603 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365253,931,933 - 3,964,834 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365253,932,118 - 3,965,651 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SAG
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15133,705,008 - 133,741,798 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115133,704,975 - 133,741,844 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215147,580,489 - 147,592,533 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Sscrofa10.215147,812,862 - 147,835,188 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SAG
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110119,343,562 - 119,383,119 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10119,344,090 - 119,382,983 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604080,120,831 - 80,162,410 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sag
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248435,844,823 - 5,870,300 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248435,837,105 - 5,870,417 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SAG
757 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium
Low 2 2
Below cutoff 5 5 19 5 6 5 6 4 11 8 8 6

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001003230 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022409547 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022409549 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022409550 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038434536 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038434537 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038434538 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000025 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ426068 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ426069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ426070 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ426072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ426073 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ426074 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ426075 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ426076 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ426078 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000273 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000064 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000302 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000025 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X98460 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSCAFT00000018744   ⟹   ENSCAFP00000017366
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2544,812,362 - 44,843,579 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000073990   ⟹   ENSCAFP00000064547
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2544,812,362 - 44,843,442 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845038830   ⟹   ENSCAFP00845030408
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2545,072,284 - 45,103,429 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845038936   ⟹   ENSCAFP00845030491
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2545,072,284 - 45,103,424 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845039069   ⟹   ENSCAFP00845030602
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2545,072,284 - 45,103,424 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845039195   ⟹   ENSCAFP00845030699
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2545,073,285 - 45,103,424 (+)Ensembl
RefSeq Acc Id: NM_001003230   ⟹   NP_001003230
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12544,812,362 - 44,843,580 (+)NCBI
Dog10K_Boxer_Tasha2545,307,685 - 45,338,815 (+)NCBI
ROS_Cfam_1.02545,072,284 - 45,103,430 (+)NCBI
UMICH_Zoey_3.12544,996,643 - 45,027,722 (+)NCBI
UNSW_CanFamBas_1.02544,842,616 - 44,873,724 (+)NCBI
UU_Cfam_GSD_1.02544,997,874 - 45,029,086 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038434536   ⟹   XP_038290464
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02545,070,391 - 45,103,430 (+)NCBI
RefSeq Acc Id: XM_038434537   ⟹   XP_038290465
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02545,060,350 - 45,103,430 (+)NCBI
RefSeq Acc Id: XM_038434538   ⟹   XP_038290466
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02545,070,391 - 45,103,423 (+)NCBI
RefSeq Acc Id: NP_001003230   ⟸   NM_001003230
- UniProtKB: Q28281 (UniProtKB/Swiss-Prot),   A0A8C0P8Z0 (UniProtKB/TrEMBL),   A0A8P0TG75 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000017366   ⟸   ENSCAFT00000018744
RefSeq Acc Id: ENSCAFP00000064547   ⟸   ENSCAFT00000073990
RefSeq Acc Id: XP_038290465   ⟸   XM_038434537
- Peptide Label: isoform X1
- UniProtKB: A0A8C0PHG6 (UniProtKB/TrEMBL),   A0A8I3P9Q1 (UniProtKB/TrEMBL),   A0A8C0P8Z0 (UniProtKB/TrEMBL),   A0A8P0TG75 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038290464   ⟸   XM_038434536
- Peptide Label: isoform X1
- UniProtKB: A0A8C0PHG6 (UniProtKB/TrEMBL),   A0A8I3P9Q1 (UniProtKB/TrEMBL),   A0A8C0P8Z0 (UniProtKB/TrEMBL),   A0A8P0TG75 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038290466   ⟸   XM_038434538
- Peptide Label: isoform X2
- UniProtKB: A0A8I3PIN4 (UniProtKB/TrEMBL),   A0A8I3PAE9 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845030699   ⟸   ENSCAFT00845039195
RefSeq Acc Id: ENSCAFP00845030408   ⟸   ENSCAFT00845038830
RefSeq Acc Id: ENSCAFP00845030491   ⟸   ENSCAFT00845038936
RefSeq Acc Id: ENSCAFP00845030602   ⟸   ENSCAFT00845039069
Protein Domains
Arrestin C-terminal-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000011811 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030022895 UniProtKB/TrEMBL
  ENSCAFG00845021999 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000018744.5 UniProtKB/TrEMBL
  ENSCAFT00000073990.2 UniProtKB/TrEMBL
  ENSCAFT00030042099.1 UniProtKB/TrEMBL
  ENSCAFT00030042127.1 UniProtKB/TrEMBL
  ENSCAFT00845038830 ENTREZGENE
  ENSCAFT00845038830.1 UniProtKB/TrEMBL
  ENSCAFT00845038936 ENTREZGENE
  ENSCAFT00845038936.1 UniProtKB/TrEMBL
  ENSCAFT00845039069.1 UniProtKB/TrEMBL
  ENSCAFT00845039195.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.640 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.60.40.840 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Arrestin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Arrestin-like_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Arrestin-like_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Arrestin_C-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Arrestin_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Arrestin_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_E-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report cfa:403906 UniProtKB/Swiss-Prot
NCBI Gene SAG ENTREZGENE
PANTHER PTHR11792 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  S-ARRESTIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Arrestin_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Arrestin_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS ARRESTIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ARRESTINS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART Arrestin_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF81296 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8C0P8Z0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0PHG6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3P9Q1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3PAE9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3PHN9_CANLF UniProtKB/TrEMBL
  A0A8I3PIN4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0TG75 ENTREZGENE
  ARRS_CANLF UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary A0A8P0TG75 UniProtKB/TrEMBL
VGNC ID VGNC:45846 ENTREZGENE