CYS1 (cystin 1) - Rat Genome Database

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Gene: CYS1 (cystin 1) Canis lupus familiaris
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Symbol: CYS1
Name: cystin 1
RGD ID: 12277165
Description: ENCODES a protein that exhibits chromatin binding (ortholog); transcription corepressor activity (ortholog); INVOLVED IN inner ear development (ortholog); kidney development (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH autosomal recessive polycystic kidney disease (ortholog); genetic disease (ortholog); stomach cancer (ortholog); FOUND IN axoneme (ortholog); ciliary basal body (ortholog); cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cystin-1; LOC102153657; uncharacterized LOC102153657
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1177,057,240 - 7,063,410 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha176,984,193 - 7,002,084 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0177,155,480 - 7,173,287 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl177,155,468 - 7,173,419 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1177,047,379 - 7,065,187 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0177,049,655 - 7,067,732 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0177,063,659 - 7,081,604 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
axoneme  (ISO)
ciliary basal body  (ISO)
cytosol  (ISO)
membrane  (ISO)
membrane raft  (ISO)
nucleus  (ISO)

Molecular Function

References

Genomics

Comparative Map Data
CYS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1177,057,240 - 7,063,410 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha176,984,193 - 7,002,084 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0177,155,480 - 7,173,287 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl177,155,468 - 7,173,419 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1177,047,379 - 7,065,187 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0177,049,655 - 7,067,732 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0177,063,659 - 7,081,604 (-)NCBIUU_Cfam_GSD_1.0
CYS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38210,056,473 - 10,080,411 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl210,056,473 - 10,080,944 (-)EnsemblGRCh38hg38GRCh38
GRCh37210,196,600 - 10,220,538 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36210,116,317 - 10,137,989 (-)NCBINCBI36Build 36hg18NCBI36
Celera210,113,148 - 10,122,388 (-)NCBICelera
Cytogenetic Map2p25.1NCBI
HuRef210,048,679 - 10,072,099 (-)NCBIHuRef
CHM1_1210,126,760 - 10,150,367 (-)NCBICHM1_1
T2T-CHM13v2.0210,085,216 - 10,109,145 (-)NCBIT2T-CHM13v2.0
Cys1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391224,715,832 - 24,731,794 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1224,715,832 - 24,731,812 (-)EnsemblGRCm39 Ensembl
GRCm381224,665,833 - 24,681,886 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1224,665,833 - 24,681,813 (-)EnsemblGRCm38mm10GRCm38
MGSCv371225,350,703 - 25,366,660 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361225,254,917 - 25,270,874 (-)NCBIMGSCv36mm8
Celera1226,126,773 - 26,142,148 (-)NCBICelera
Cytogenetic Map12A1.3NCBI
cM Map128.49NCBI
Cys1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8647,029,440 - 47,046,671 (-)NCBIGRCr8
mRatBN7.2641,300,836 - 41,318,071 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl641,300,836 - 41,318,071 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx641,623,662 - 41,640,797 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0641,938,469 - 41,955,604 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0641,371,615 - 41,388,750 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0643,844,937 - 43,862,131 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl643,844,937 - 43,862,131 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0660,716,420 - 60,733,664 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4642,311,213 - 42,328,045 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera640,588,514 - 40,604,945 (-)NCBICelera
Cytogenetic Map6q16NCBI
Cys1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554875,455,820 - 5,461,362 (-)NCBIChiLan1.0ChiLan1.0
CYS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v212116,436,015 - 116,462,665 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A116,443,330 - 116,466,636 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A10,053,361 - 10,078,264 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
CYS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3126,398,303 - 126,412,560 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13126,398,302 - 126,411,951 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
CYS1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11497,549,886 - 97,572,458 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1497,551,009 - 97,570,710 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604514,739,608 - 14,764,133 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in CYS1
112 total Variants

Expression


Sequence


RefSeq Acc Id: ENSCAFT00845045714   ⟹   ENSCAFP00845035875
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl177,155,468 - 7,173,419 (-)Ensembl
RefSeq Acc Id: XM_038453284   ⟹   XP_038309212
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha176,984,193 - 7,002,084 (-)NCBI
RefSeq Acc Id: XM_038498228   ⟹   XP_038354156
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1177,047,379 - 7,065,187 (-)NCBI
RefSeq Acc Id: XM_038560764   ⟹   XP_038416692
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0177,063,659 - 7,081,604 (-)NCBI
RefSeq Acc Id: XM_038624671   ⟹   XP_038480599
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0177,049,655 - 7,067,732 (-)NCBI
RefSeq Acc Id: XM_038690702   ⟹   XP_038546630
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0177,155,480 - 7,173,287 (-)NCBI
RefSeq Acc Id: XP_038354156   ⟸   XM_038498228
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038480599   ⟸   XM_038624671
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038546630   ⟸   XM_038690702
- Peptide Label: isoform X1
- UniProtKB: A0A8I3PYJ0 (UniProtKB/TrEMBL),   A0A8C0MLW8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038309212   ⟸   XM_038453284
- Peptide Label: isoform X1
- UniProtKB: A0A8P0PGC7 (UniProtKB/TrEMBL),   A0A8C0LTR6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038416692   ⟸   XM_038560764
- Peptide Label: isoform X1
- UniProtKB: A0A8C0MLW8 (UniProtKB/TrEMBL),   A0A8I3PYJ0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845035875   ⟸   ENSCAFT00845045714


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000051171 UniProtKB/TrEMBL
  ENSCAFG00030005509 UniProtKB/TrEMBL
  ENSCAFG00040006855 UniProtKB/TrEMBL
  ENSCAFG00845025907 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000097136.1 UniProtKB/TrEMBL
  ENSCAFT00030010122.1 UniProtKB/TrEMBL
  ENSCAFT00040012752.1 UniProtKB/TrEMBL
  ENSCAFT00845045714 ENTREZGENE
  ENSCAFT00845045714.1 UniProtKB/TrEMBL
NCBI Gene LOC102153657 ENTREZGENE
UniProt A0A8C0LTR6 ENTREZGENE
  A0A8C0MLW8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3PYJ0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0PGC7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-01-12 CYS1  cystin 1  LOC102153657  uncharacterized LOC102153657  Symbol and/or name change 5135510 APPROVED