NDUFB2 (NADH:ubiquinone oxidoreductase subunit B2) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: NDUFB2 (NADH:ubiquinone oxidoreductase subunit B2) Canis lupus familiaris
Analyze
Symbol: NDUFB2
Name: NADH:ubiquinone oxidoreductase subunit B2
RGD ID: 12276345
Description: INVOLVED IN mitochondrial respiratory chain complex I assembly (inferred); ASSOCIATED WITH genetic disease (ortholog); pleomorphic xanthoastrocytoma (ortholog); RASopathy (ortholog); FOUND IN mitochondrial respiratory chain complex I (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1168,329,367 - 8,341,292 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl168,265,104 - 8,341,252 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha169,173,242 - 9,185,169 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0168,250,126 - 8,262,088 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl168,186,070 - 8,262,049 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1168,201,098 - 8,213,033 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0168,045,839 - 8,057,739 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0168,114,026 - 8,125,939 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
NDUFB2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1168,329,367 - 8,341,292 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl168,265,104 - 8,341,252 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha169,173,242 - 9,185,169 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0168,250,126 - 8,262,088 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl168,186,070 - 8,262,049 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1168,201,098 - 8,213,033 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0168,045,839 - 8,057,739 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0168,114,026 - 8,125,939 (-)NCBIUU_Cfam_GSD_1.0
NDUFB2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387140,696,708 - 140,706,643 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7140,690,777 - 140,722,790 (+)EnsemblGRCh38hg38GRCh38
GRCh377140,396,508 - 140,406,443 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367140,042,950 - 140,052,915 (+)NCBINCBI36Build 36hg18NCBI36
Build 347139,849,664 - 139,859,628NCBI
Celera7135,118,531 - 135,128,501 (+)NCBICelera
Cytogenetic Map7q34NCBI
HuRef7134,692,161 - 134,702,093 (+)NCBIHuRef
CHM1_17140,330,733 - 140,340,698 (+)NCBICHM1_1
T2T-CHM13v2.07142,010,885 - 142,020,820 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27139,734,658 - 139,744,623 (+)NCBI
Ndufb2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39639,569,499 - 39,576,777 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl639,569,508 - 39,580,316 (+)EnsemblGRCm39 Ensembl
GRCm38639,592,565 - 39,599,843 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl639,592,574 - 39,603,382 (+)EnsemblGRCm38mm10GRCm38
MGSCv37639,542,582 - 39,549,470 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36639,522,190 - 39,529,078 (+)NCBIMGSCv36mm8
Celera639,577,439 - 39,584,327 (+)NCBICelera
Cytogenetic Map6B1NCBI
cM Map618.42NCBI
Ndufb2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8469,334,307 - 69,341,394 (+)NCBIGRCr8
mRatBN7.2468,367,526 - 68,374,609 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl468,348,864 - 68,374,608 (+)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 Ensembl1546,536,062 - 46,536,851 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx473,289,674 - 73,296,643 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0469,210,806 - 69,217,771 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0467,616,122 - 67,623,070 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0467,378,188 - 67,385,267 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl467,378,188 - 67,385,266 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0467,185,340 - 67,192,419 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4467,099,841 - 67,106,920 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1467,375,973 - 67,383,049 (+)NCBI
Celera463,372,194 - 63,379,273 (+)NCBICelera
Cytogenetic Map4q23NCBI
Ndufb2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554942,723,740 - 2,731,054 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554942,723,740 - 2,731,054 (-)NCBIChiLan1.0ChiLan1.0
NDUFB2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26177,486,651 - 177,513,797 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1729,496,908 - 29,522,373 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07132,629,353 - 132,654,824 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17145,101,604 - 145,128,881 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7145,101,602 - 145,128,866 (+)Ensemblpanpan1.1panPan2
Ndufb2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511814,502,974 - 14,508,015 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365924,713,024 - 4,715,441 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365924,711,790 - 4,716,829 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NDUFB2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl189,132,432 - 9,150,543 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1189,135,359 - 9,150,513 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2189,639,304 - 9,654,459 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NDUFB2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121109,474,696 - 109,495,013 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl21109,474,356 - 109,482,526 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660726,121,375 - 6,130,808 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ndufb2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476520,753,774 - 20,762,109 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476520,753,756 - 20,762,110 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in NDUFB2
150 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High 4 3
Medium 5 1 22 6 6 6 6 3 12 8 10 6
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000006318   ⟹   ENSCAFP00000005853
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl168,265,104 - 8,341,252 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845055194   ⟹   ENSCAFP00845043410
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl168,186,070 - 8,262,049 (-)Ensembl
RefSeq Acc Id: XM_003432065   ⟹   XP_003432113
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1168,329,367 - 8,341,292 (-)NCBI
Dog10K_Boxer_Tasha169,173,242 - 9,185,169 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038497053   ⟹   XP_038352981
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1168,201,098 - 8,213,033 (-)NCBI
RefSeq Acc Id: XM_038559391   ⟹   XP_038415319
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0168,114,026 - 8,125,939 (-)NCBI
RefSeq Acc Id: XM_038623372   ⟹   XP_038479300
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0168,045,839 - 8,057,739 (-)NCBI
RefSeq Acc Id: XM_038689091   ⟹   XP_038545019
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0168,250,126 - 8,262,088 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_003432113   ⟸   XM_003432065
- UniProtKB: A0A8C0MHW9 (UniProtKB/TrEMBL),   A0A8C0L7H1 (UniProtKB/TrEMBL),   A0A8I3Q8I7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000005853   ⟸   ENSCAFT00000006318
RefSeq Acc Id: XP_038352981   ⟸   XM_038497053
RefSeq Acc Id: XP_038479300   ⟸   XM_038623372
RefSeq Acc Id: XP_038545019   ⟸   XM_038689091
- UniProtKB: A0A8C0MHW9 (UniProtKB/TrEMBL),   A0A8C0L7H1 (UniProtKB/TrEMBL),   A0A8I3Q8I7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038415319   ⟸   XM_038559391
- UniProtKB: A0A8C0L7H1 (UniProtKB/TrEMBL),   A0A8C0MHW9 (UniProtKB/TrEMBL),   A0A8I3Q8I7 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845043410   ⟸   ENSCAFT00845055194

Promoters
RGD ID:13686034
Promoter ID:EPDNEW_C4103
Type:multiple initiation site
Name:NDUFB2_1
Description:NADH:ubiquinone oxidoreductase subunit B2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1168,341,256 - 8,341,316EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000003930 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030006367 UniProtKB/TrEMBL
  ENSCAFG00040007561 UniProtKB/TrEMBL
  ENSCAFG00845031044 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000006318.5 UniProtKB/TrEMBL
  ENSCAFT00030011690.1 UniProtKB/TrEMBL
  ENSCAFT00040014082.1 UniProtKB/TrEMBL
  ENSCAFT00845055194 ENTREZGENE
  ENSCAFT00845055194.1 UniProtKB/TrEMBL
InterPro NDUFB2_animal UniProtKB/TrEMBL
KEGG Report cfa:100683846 UniProtKB/TrEMBL
NCBI Gene NDUFB2 ENTREZGENE
PANTHER NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 2, MITOCHONDRIAL UniProtKB/TrEMBL
  PTHR15223 UniProtKB/TrEMBL
Pfam NADH_B2 UniProtKB/TrEMBL
UniProt A0A8C0L7H1 ENTREZGENE
  A0A8C0MHW9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3Q8I7 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:43701 ENTREZGENE