RAPSN (receptor associated protein of the synapse) - Rat Genome Database

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Gene: RAPSN (receptor associated protein of the synapse) Canis lupus familiaris
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Symbol: RAPSN
Name: receptor associated protein of the synapse
RGD ID: 12274598
Description: ENCODES a protein that exhibits ionotropic glutamate receptor binding (ortholog); INVOLVED IN establishment of protein localization to postsynaptic membrane (ortholog); motor neuron apoptotic process (ortholog); positive regulation of motor neuron apoptotic process (ortholog); PARTICIPATES IN acetylcholine signaling pathway via nicotinic acetylcholine receptor; ASSOCIATED WITH autoimmune disease (ortholog); congenital disorder of glycosylation type IIc (ortholog); congenital myasthenic syndrome (ortholog); FOUND IN neuromuscular junction (ortholog); postsynaptic membrane (ortholog); postsynaptic specialization membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 43 kDa receptor-associated protein of the synapse
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11842,199,160 - 42,210,668 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1842,199,412 - 42,210,673 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1840,930,029 - 40,941,208 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01842,855,197 - 42,866,378 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1842,855,420 - 42,866,216 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11842,341,801 - 42,352,980 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01841,896,689 - 41,907,866 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01842,626,215 - 42,637,394 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
RAPSN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11842,199,160 - 42,210,668 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1842,199,412 - 42,210,673 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1840,930,029 - 40,941,208 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01842,855,197 - 42,866,378 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1842,855,420 - 42,866,216 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11842,341,801 - 42,352,980 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01841,896,689 - 41,907,866 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01842,626,215 - 42,637,394 (+)NCBIUU_Cfam_GSD_1.0
RAPSN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381147,437,764 - 47,449,136 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1147,437,764 - 47,449,143 (-)EnsemblGRCh38hg38GRCh38
GRCh371147,459,315 - 47,470,688 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361147,415,891 - 47,427,306 (-)NCBINCBI36Build 36hg18NCBI36
Build 341147,415,890 - 47,427,306NCBI
Celera1147,601,051 - 47,612,463 (-)NCBICelera
Cytogenetic Map11p11.2NCBI
HuRef1147,159,075 - 47,170,494 (-)NCBIHuRef
CHM1_11147,458,570 - 47,469,991 (-)NCBICHM1_1
T2T-CHM13v2.01147,597,603 - 47,608,976 (-)NCBIT2T-CHM13v2.0
Rapsn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39290,864,594 - 90,876,074 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl290,865,965 - 90,876,074 (+)EnsemblGRCm39 Ensembl
GRCm38291,035,472 - 91,045,729 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl291,035,620 - 91,045,729 (+)EnsemblGRCm38mm10GRCm38
MGSCv37290,875,784 - 90,885,886 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36290,836,478 - 90,846,568 (+)NCBIMGSCv36mm8
Celera292,420,152 - 92,430,248 (+)NCBICelera
Cytogenetic Map2E1NCBI
cM Map250.44NCBI
Rapsn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8397,470,891 - 97,480,196 (+)NCBIGRCr8
mRatBN7.2377,015,073 - 77,024,378 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl376,983,471 - 77,024,373 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx380,493,612 - 80,502,907 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0389,092,627 - 89,101,922 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0386,943,726 - 86,953,069 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0379,859,815 - 79,869,486 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl379,860,179 - 79,869,524 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0386,568,568 - 86,578,239 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4375,396,836 - 75,406,115 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1375,293,208 - 75,302,485 (+)NCBI
Celera376,223,882 - 76,233,161 (+)NCBICelera
Cytogenetic Map3q24NCBI
Rapsn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955422826,727 - 834,289 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955422826,556 - 834,483 (+)NCBIChiLan1.0ChiLan1.0
RAPSN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2949,642,069 - 49,656,586 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11149,661,853 - 49,676,291 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01147,387,324 - 47,398,579 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11147,940,530 - 47,951,667 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1147,940,530 - 47,951,667 (-)Ensemblpanpan1.1panPan2
Rapsn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494719,680,416 - 19,692,511 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365621,795,905 - 1,804,181 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365621,796,087 - 1,804,153 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RAPSN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1117,867,721 - 17,887,162 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl117,868,888 - 17,887,164 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038115,165,684 - 115,176,850 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rapsn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247671,351,370 - 1,358,187 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247671,350,820 - 1,358,107 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in RAPSN
150 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 3 6
Low 1 2 13 5 6 5 4 3 8 8 1
Below cutoff 4 9 1 1 2 9 2 5

Sequence


RefSeq Acc Id: ENSCAFT00000013802   ⟹   ENSCAFP00000012765
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1842,199,412 - 42,210,673 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000068306   ⟹   ENSCAFP00000051493
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1842,199,412 - 42,209,979 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000076333   ⟹   ENSCAFP00000065382
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1842,199,412 - 42,210,673 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000090260   ⟹   ENSCAFP00000056172
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1842,199,412 - 42,210,673 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000090999   ⟹   ENSCAFP00000065147
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1842,199,412 - 42,209,454 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845037006   ⟹   ENSCAFP00845028976
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1842,855,420 - 42,866,216 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845037073   ⟹   ENSCAFP00845029033
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1842,855,420 - 42,866,216 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845037115   ⟹   ENSCAFP00845029069
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1842,855,420 - 42,866,216 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845037332   ⟹   ENSCAFP00845029242
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1842,855,420 - 42,865,688 (+)Ensembl
RefSeq Acc Id: XM_038424371   ⟹   XP_038280299
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01842,855,197 - 42,866,378 (+)NCBI
RefSeq Acc Id: XM_038500712   ⟹   XP_038356640
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11842,341,801 - 42,352,980 (+)NCBI
RefSeq Acc Id: XM_038563303   ⟹   XP_038419231
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01842,626,215 - 42,637,394 (+)NCBI
RefSeq Acc Id: XM_038627425   ⟹   XP_038483353
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01841,896,689 - 41,907,866 (+)NCBI
RefSeq Acc Id: XM_845002   ⟹   XP_850095
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11842,199,160 - 42,210,668 (+)NCBI
Dog10K_Boxer_Tasha1840,930,029 - 40,941,208 (+)NCBI
Sequence:
RefSeq Acc Id: XP_850095   ⟸   XM_845002
- UniProtKB: A0A8C0QM89 (UniProtKB/TrEMBL),   A0A8P0TGK5 (UniProtKB/TrEMBL),   A0A8C0LPC0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000051493   ⟸   ENSCAFT00000068306
RefSeq Acc Id: ENSCAFP00000065382   ⟸   ENSCAFT00000076333
RefSeq Acc Id: ENSCAFP00000012765   ⟸   ENSCAFT00000013802
RefSeq Acc Id: ENSCAFP00000056172   ⟸   ENSCAFT00000090260
RefSeq Acc Id: ENSCAFP00000065147   ⟸   ENSCAFT00000090999
RefSeq Acc Id: XP_038356640   ⟸   XM_038500712
RefSeq Acc Id: XP_038483353   ⟸   XM_038627425
RefSeq Acc Id: XP_038280299   ⟸   XM_038424371
- UniProtKB: A0A8C0M6C4 (UniProtKB/TrEMBL),   A0A8I3P6H1 (UniProtKB/TrEMBL),   A0A8C0LPC0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038419231   ⟸   XM_038563303
- UniProtKB: A0A8C0LPC0 (UniProtKB/TrEMBL),   A0A8C0QM89 (UniProtKB/TrEMBL),   A0A8P0TGK5 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845028976   ⟸   ENSCAFT00845037006
RefSeq Acc Id: ENSCAFP00845029033   ⟸   ENSCAFT00845037073
RefSeq Acc Id: ENSCAFP00845029242   ⟸   ENSCAFT00845037332
RefSeq Acc Id: ENSCAFP00845029069   ⟸   ENSCAFT00845037115
Promoters
RGD ID:13686509
Promoter ID:EPDNEW_C4577
Type:single initiation site
Name:RAPSN_1
Description:receptor associated protein of the synapse
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11842,199,536 - 42,199,596EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000008690 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030004313 UniProtKB/TrEMBL
  ENSCAFG00040008174 UniProtKB/TrEMBL
  ENSCAFG00845020952 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000013802.5 UniProtKB/TrEMBL
  ENSCAFT00000068306.2 UniProtKB/TrEMBL
  ENSCAFT00000076333.2 UniProtKB/TrEMBL
  ENSCAFT00000090260.2 UniProtKB/TrEMBL
  ENSCAFT00000090999.2 UniProtKB/TrEMBL
  ENSCAFT00030007985.1 UniProtKB/TrEMBL
  ENSCAFT00030008009.1 UniProtKB/TrEMBL
  ENSCAFT00030008024.1 UniProtKB/TrEMBL
  ENSCAFT00030008058.1 UniProtKB/TrEMBL
  ENSCAFT00040015286.1 UniProtKB/TrEMBL
  ENSCAFT00040015297.1 UniProtKB/TrEMBL
  ENSCAFT00040015306.1 UniProtKB/TrEMBL
  ENSCAFT00040015325.1 UniProtKB/TrEMBL
  ENSCAFT00845037006 ENTREZGENE
  ENSCAFT00845037006.1 UniProtKB/TrEMBL
  ENSCAFT00845037073.1 UniProtKB/TrEMBL
  ENSCAFT00845037115.1 UniProtKB/TrEMBL
  ENSCAFT00845037332.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.10 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
InterPro Postsynaptic UniProtKB/TrEMBL
  Postsynaptic_CS UniProtKB/TrEMBL
  Rapsyn_myristoylation/link_N UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/TrEMBL
  TPR_repeat UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
KEGG Report cfa:609725 UniProtKB/TrEMBL
NCBI Gene RAPSN ENTREZGENE
PANTHER 43 KDA RECEPTOR-ASSOCIATED PROTEIN OF THE SYNAPSE UniProtKB/TrEMBL
  43 KDA RECEPTOR-ASSOCIATED PROTEIN OF THE SYNAPSE UniProtKB/TrEMBL
Pfam Rapsyn_N UniProtKB/TrEMBL
  TPR_8 UniProtKB/TrEMBL
  TPR_MalT UniProtKB/TrEMBL
  zf-RING_2 UniProtKB/TrEMBL
PRINTS POSTSYNAPTIC UniProtKB/TrEMBL
PROSITE 43_KD_POSTSYNAPTIC UniProtKB/TrEMBL
  TPR UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
SMART RING UniProtKB/TrEMBL
  TPR UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
  SSF48452 UniProtKB/TrEMBL
UniProt A0A8C0LPC0 ENTREZGENE
  A0A8C0M6C4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0MBR8_CANLF UniProtKB/TrEMBL
  A0A8C0MHB1_CANLF UniProtKB/TrEMBL
  A0A8C0QF50_CANLF UniProtKB/TrEMBL
  A0A8C0QG37_CANLF UniProtKB/TrEMBL
  A0A8C0QJQ9_CANLF UniProtKB/TrEMBL
  A0A8C0QM89 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0RCI3_CANLF UniProtKB/TrEMBL
  A0A8I3P6H1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3PBU0_CANLF UniProtKB/TrEMBL
  A0A8I3PFV0_CANLF UniProtKB/TrEMBL
  A0A8I3S4P1_CANLF UniProtKB/TrEMBL
  A0A8P0SDS1_CANLF UniProtKB/TrEMBL
  A0A8P0TGK5 ENTREZGENE
UniProt Secondary A0A8P0P1B0 UniProtKB/TrEMBL
  A0A8P0PE07 UniProtKB/TrEMBL
  A0A8P0T8C8 UniProtKB/TrEMBL
  A0A8P0TGK5 UniProtKB/TrEMBL
VGNC ID VGNC:45350 ENTREZGENE