MARVELD3 (MARVEL domain containing 3) - Rat Genome Database

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Gene: MARVELD3 (MARVEL domain containing 3) Canis lupus familiaris
Analyze
Symbol: MARVELD3
Name: MARVEL domain containing 3
RGD ID: 12274528
Description: ENCODES a protein that exhibits mitogen-activated protein kinase kinase kinase binding (ortholog); INVOLVED IN bicellular tight junction assembly (ortholog); cell-cell junction organization (ortholog); negative regulation of epithelial cell migration (ortholog); ASSOCIATED WITH autosomal dominant dyskeratosis congenita 6 (ortholog); genetic disease (ortholog); FOUND IN bicellular tight junction (ortholog); cytoplasmic vesicle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: MARVEL domain-containing protein 3
RGD Orthologs
Human
Mouse
Rat
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1577,412,353 - 77,421,032 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl577,412,101 - 77,425,578 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha577,373,388 - 77,388,132 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0577,850,906 - 77,865,672 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1577,670,919 - 77,685,750 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0577,494,107 - 77,508,903 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0577,993,065 - 78,007,828 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
MARVELD3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1577,412,353 - 77,421,032 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl577,412,101 - 77,425,578 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha577,373,388 - 77,388,132 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0577,850,906 - 77,865,672 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1577,670,919 - 77,685,750 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0577,494,107 - 77,508,903 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0577,993,065 - 78,007,828 (+)NCBIUU_Cfam_GSD_1.0
MARVELD3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381671,626,184 - 71,641,965 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1671,626,161 - 71,642,114 (+)EnsemblGRCh38hg38GRCh38
GRCh371671,660,087 - 71,675,868 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361670,217,571 - 70,233,369 (+)NCBINCBI36Build 36hg18NCBI36
Build 341670,217,589 - 70,226,732NCBI
Celera1655,976,129 - 55,991,929 (+)NCBICelera
Cytogenetic Map16q22.2NCBI
HuRef1657,428,132 - 57,443,707 (+)NCBIHuRef
CHM1_11673,072,839 - 73,088,630 (+)NCBICHM1_1
T2T-CHM13v2.01677,443,349 - 77,459,129 (+)NCBIT2T-CHM13v2.0
Marveld3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398110,674,541 - 110,688,837 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8110,674,546 - 110,688,835 (-)EnsemblGRCm39 Ensembl
GRCm388109,947,909 - 109,962,205 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8109,947,914 - 109,962,203 (-)EnsemblGRCm38mm10GRCm38
MGSCv378112,471,809 - 112,486,105 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368112,837,043 - 112,851,301 (-)NCBIMGSCv36mm8
Celera8114,169,861 - 114,184,142 (-)NCBICelera
Cytogenetic Map8D3NCBI
cM Map857.38NCBI
Marveld3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81954,818,180 - 54,832,871 (-)NCBIGRCr8
mRatBN7.21937,908,727 - 37,923,420 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1937,905,638 - 37,923,420 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1944,721,040 - 44,735,720 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01945,374,382 - 45,389,062 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01947,683,994 - 47,698,676 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01941,710,076 - 41,724,923 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1941,710,102 - 41,724,923 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01952,533,493 - 52,548,323 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41939,815,223 - 39,829,914 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1937,312,319 - 37,327,013 (-)NCBICelera
Cytogenetic Map19q12NCBI
MARVELD3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21882,517,624 - 82,533,582 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11688,448,452 - 88,464,397 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01653,369,080 - 53,385,031 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11671,463,722 - 71,477,951 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1671,463,824 - 71,477,631 (+)Ensemblpanpan1.1panPan2
Marveld3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934937,432,404 - 37,450,390 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647522,146,100 - 22,156,702 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647522,141,276 - 22,156,649 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MARVELD3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl614,616,481 - 14,625,983 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1614,616,508 - 14,630,798 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2614,109,585 - 14,123,646 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MARVELD3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1554,748,029 - 54,765,007 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl554,748,061 - 54,765,252 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604717,551,303 - 17,567,015 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Marveld3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474613,898,857 - 13,914,032 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in MARVELD3
137 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 2 5 5
Low 3 15 6 6 6 12 8 5 1
Below cutoff 5 2 6 6 5

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_022419454 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038477224 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038477225 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038477226 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038528723 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038528732 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038528742 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038538425 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038538427 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038538428 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038602546 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038602547 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038602548 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038667153 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038667154 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038667155 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000066 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000089 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSCAFT00000032160   ⟹   ENSCAFP00000029948
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl577,412,101 - 77,425,578 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000044505   ⟹   ENSCAFP00000038453
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl577,412,101 - 77,420,633 (+)Ensembl
RefSeq Acc Id: XM_038477224   ⟹   XP_038333152
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1577,671,455 - 77,685,750 (+)NCBI
RefSeq Acc Id: XM_038477225   ⟹   XP_038333153
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1577,670,927 - 77,685,750 (+)NCBI
RefSeq Acc Id: XM_038477226   ⟹   XP_038333154
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1577,670,919 - 77,679,958 (+)NCBI
RefSeq Acc Id: XM_038528723   ⟹   XP_038384651
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha577,373,923 - 77,388,132 (+)NCBI
RefSeq Acc Id: XM_038528732   ⟹   XP_038384660
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha577,373,395 - 77,388,132 (+)NCBI
RefSeq Acc Id: XM_038528742   ⟹   XP_038384670
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha577,373,388 - 77,382,776 (+)NCBI
RefSeq Acc Id: XM_038538425   ⟹   XP_038394353
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0577,993,600 - 78,007,828 (+)NCBI
RefSeq Acc Id: XM_038538427   ⟹   XP_038394355
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0577,993,072 - 78,007,828 (+)NCBI
RefSeq Acc Id: XM_038538428   ⟹   XP_038394356
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0577,993,065 - 78,002,471 (+)NCBI
RefSeq Acc Id: XM_038602546   ⟹   XP_038458474
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0577,494,633 - 77,508,903 (+)NCBI
RefSeq Acc Id: XM_038602547   ⟹   XP_038458475
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0577,494,115 - 77,508,903 (+)NCBI
RefSeq Acc Id: XM_038602548   ⟹   XP_038458476
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0577,494,107 - 77,503,506 (+)NCBI
RefSeq Acc Id: XM_038667153   ⟹   XP_038523081
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0577,851,443 - 77,865,672 (+)NCBI
RefSeq Acc Id: XM_038667154   ⟹   XP_038523082
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0577,850,913 - 77,865,672 (+)NCBI
RefSeq Acc Id: XM_038667155   ⟹   XP_038523083
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0577,850,906 - 77,860,316 (+)NCBI
RefSeq Acc Id: ENSCAFP00000038453   ⟸   ENSCAFT00000044505
RefSeq Acc Id: ENSCAFP00000029948   ⟸   ENSCAFT00000032160
RefSeq Acc Id: XP_038333154   ⟸   XM_038477226
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038333153   ⟸   XM_038477225
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038333152   ⟸   XM_038477224
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038458476   ⟸   XM_038602548
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038458475   ⟸   XM_038602547
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038458474   ⟸   XM_038602546
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038523083   ⟸   XM_038667155
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038523082   ⟸   XM_038667154
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038523081   ⟸   XM_038667153
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038384670   ⟸   XM_038528742
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038384660   ⟸   XM_038528732
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038384651   ⟸   XM_038528723
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038394356   ⟸   XM_038538428
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038394355   ⟸   XM_038538427
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038394353   ⟸   XM_038538425
- Peptide Label: isoform X1
Protein Domains
MARVEL


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000032449 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030009193 UniProtKB/TrEMBL
  ENSCAFG00845005682 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000032160.5 UniProtKB/TrEMBL
  ENSCAFT00000044505.3 UniProtKB/TrEMBL
  ENSCAFT00030016980.1 UniProtKB/TrEMBL
  ENSCAFT00030017052.1 UniProtKB/TrEMBL
  ENSCAFT00845010079.1 UniProtKB/TrEMBL
  ENSCAFT00845010090.1 UniProtKB/TrEMBL
InterPro Marvel UniProtKB/TrEMBL
NCBI Gene MARVELD3 ENTREZGENE
PANTHER GEO08273P1-RELATED UniProtKB/TrEMBL
  GEO08273P1-RELATED UniProtKB/TrEMBL
  MARVEL DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN UniProtKB/TrEMBL
PROSITE MARVEL UniProtKB/TrEMBL
UniProt A0A8C0MUC4_CANLF UniProtKB/TrEMBL
  A0A8C0RG90_CANLF UniProtKB/TrEMBL
  A0A8I3MXJ8_CANLF UniProtKB/TrEMBL
  A0A8I3RSU0_CANLF UniProtKB/TrEMBL
UniProt Secondary A0A8P0NQ70 UniProtKB/TrEMBL
  A0A8P0SP37 UniProtKB/TrEMBL
VGNC ID VGNC:53422 ENTREZGENE