HYAL1 (hyaluronidase 1) - Rat Genome Database

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Gene: HYAL1 (hyaluronidase 1) Canis lupus familiaris
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Symbol: HYAL1
Name: hyaluronidase 1
RGD ID: 12273849
Description: ENCODES a protein that exhibits hyaluronan synthase activity (ortholog); hyalurononglucosaminidase activity (ortholog); virus receptor activity (ortholog); INVOLVED IN cartilage development (ortholog); cellular response to interleukin-1 (ortholog); cellular response to pH (ortholog); ASSOCIATED WITH Kidney Reperfusion Injury (ortholog); mucopolysaccharidosis (ortholog); mucopolysaccharidosis IX (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic vesicle (ortholog); extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: hyaluronidase-1; hyaluronoglucosaminidase 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12039,035,924 - 39,040,443 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2039,038,514 - 39,040,368 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2038,955,644 - 38,961,480 (+)NCBI
ROS_Cfam_1.02039,390,640 - 39,396,476 (+)NCBI
UMICH_Zoey_3.12038,758,465 - 38,764,301 (+)NCBI
UNSW_CanFamBas_1.02039,162,014 - 39,167,822 (+)NCBI
UU_Cfam_GSD_1.02039,442,045 - 39,447,881 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
HYAL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12039,035,924 - 39,040,443 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2039,038,514 - 39,040,368 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2038,955,644 - 38,961,480 (+)NCBI
ROS_Cfam_1.02039,390,640 - 39,396,476 (+)NCBI
UMICH_Zoey_3.12038,758,465 - 38,764,301 (+)NCBI
UNSW_CanFamBas_1.02039,162,014 - 39,167,822 (+)NCBI
UU_Cfam_GSD_1.02039,442,045 - 39,447,881 (+)NCBI
HYAL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl350,299,890 - 50,312,381 (-)EnsemblGRCh38hg38GRCh38
GRCh38350,299,889 - 50,312,951 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37350,337,324 - 50,349,812 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36350,312,324 - 50,324,816 (-)NCBINCBI36hg18NCBI36
Build 34350,312,324 - 50,316,008NCBI
Celera350,310,151 - 50,322,647 (-)NCBI
Cytogenetic Map3p21.31NCBI
HuRef350,393,063 - 50,405,514 (-)NCBIHuRef
CHM1_1350,289,626 - 50,302,099 (-)NCBICHM1_1
Hyal1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399107,454,149 - 107,458,898 (+)NCBIGRCm39mm39
GRCm39 Ensembl9107,454,126 - 107,458,909 (+)Ensembl
GRCm389107,576,950 - 107,581,699 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9107,576,927 - 107,581,710 (+)EnsemblGRCm38mm10GRCm38
MGSCv379107,479,283 - 107,482,468 (+)NCBIGRCm37mm9NCBIm37
MGSCv369107,435,053 - 107,438,238 (+)NCBImm8
Celera9107,185,725 - 107,188,909 (+)NCBICelera
Cytogenetic Map9F1NCBI
cM Map958.17NCBI
Hyal1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.28108,250,654 - 108,254,526 (+)NCBI
Rnor_6.0 Ensembl8116,332,796 - 116,335,435 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.08116,332,834 - 116,337,522 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.08115,689,184 - 115,691,497 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48112,824,562 - 112,826,875 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.18112,844,016 - 112,846,330 (+)NCBI
Celera8107,557,375 - 107,559,688 (+)NCBICelera
Cytogenetic Map8q32NCBI
Hyal1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555322,112,771 - 2,115,952 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555322,113,016 - 2,116,093 (-)NCBIChiLan1.0ChiLan1.0
HYAL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1351,463,239 - 51,473,030 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl351,463,239 - 51,467,286 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0350,228,491 - 50,238,798 (-)NCBIMhudiblu_PPA_v0panPan3
Hyal1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560265,077,652 - 65,080,619 (-)NCBI
SpeTri2.0NW_0049365291,838,212 - 1,842,399 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HYAL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1332,793,569 - 32,800,796 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11332,798,135 - 32,800,705 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21335,976,670 - 35,979,238 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap13q21NCBI
HYAL1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12211,689,123 - 11,693,144 (-)NCBI
ChlSab1.1 Ensembl2211,688,970 - 11,693,183 (-)Ensembl
Vero_WHO_p1.0NW_023666041155,294,855 - 155,298,582 (+)NCBI
Hyal1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247304,161,204 - 4,165,554 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium
Low 1 3
Below cutoff 5 5 22 6 5 6 6 6 12 8 7 6

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000016857   ⟹   ENSCAFP00000015600
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2039,038,514 - 39,040,368 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000081291   ⟹   ENSCAFP00000058697
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2039,038,514 - 39,040,368 (+)Ensembl
RefSeq Acc Id: XM_005632508   ⟹   XP_005632565
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12039,035,924 - 39,040,443 (+)NCBI
Dog10K_Boxer_Tasha2038,955,644 - 38,961,480 (+)NCBI
Sequence:
RefSeq Acc Id: XM_022406690   ⟹   XP_022262398
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12039,038,025 - 39,040,411 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038427692   ⟹   XP_038283620
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02039,390,640 - 39,396,476 (+)NCBI
RefSeq Acc Id: XM_038503378   ⟹   XP_038359306
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12038,758,465 - 38,764,301 (+)NCBI
RefSeq Acc Id: XM_038566379   ⟹   XP_038422307
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02039,442,045 - 39,447,881 (+)NCBI
RefSeq Acc Id: XM_038630529   ⟹   XP_038486457
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02039,162,014 - 39,167,822 (+)NCBI
RefSeq Acc Id: XM_845674   ⟹   XP_850767
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12039,038,027 - 39,040,443 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_005632565   ⟸   XM_005632508
- Sequence:
RefSeq Acc Id: XP_850767   ⟸   XM_845674
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_022262398   ⟸   XM_022406690
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSCAFP00000015600   ⟸   ENSCAFT00000016857
RefSeq Acc Id: ENSCAFP00000058697   ⟸   ENSCAFT00000081291
RefSeq Acc Id: XP_038359306   ⟸   XM_038503378
RefSeq Acc Id: XP_038486457   ⟸   XM_038630529
RefSeq Acc Id: XP_038283620   ⟸   XM_038427692
RefSeq Acc Id: XP_038422307   ⟸   XM_038566379


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000010599 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00000015600 UniProtKB/TrEMBL
  ENSCAFP00000058697 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000016857 UniProtKB/TrEMBL
  ENSCAFT00000081291 UniProtKB/TrEMBL
Gene3D-CATH 3.20.20.70 UniProtKB/TrEMBL
InterPro Aldolase_TIM UniProtKB/TrEMBL
  Glycoside_hydrolase_SF UniProtKB/TrEMBL
  Hyaluronidase UniProtKB/TrEMBL
NCBI Gene HYAL1 ENTREZGENE
PANTHER PTHR11769 UniProtKB/TrEMBL
Pfam Glyco_hydro_56 UniProtKB/TrEMBL
PIRSF Hyaluronidase UniProtKB/TrEMBL
PRINTS GLHYDRLASE56 UniProtKB/TrEMBL
Superfamily-SCOP SSF51445 UniProtKB/TrEMBL
UniProt A0A5F4CWI4_CANLF UniProtKB/TrEMBL
  F1PSX9_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:54314 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-08-07 HYAL1  hyaluronidase 1    hyaluronoglucosaminidase 1  Symbol and/or name change 5135510 APPROVED