ABHD5 (abhydrolase domain containing 5, lysophosphatidic acid acyltransferase) - Rat Genome Database

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Gene: ABHD5 (abhydrolase domain containing 5, lysophosphatidic acid acyltransferase) Canis lupus familiaris
Analyze
Symbol: ABHD5
Name: abhydrolase domain containing 5, lysophosphatidic acid acyltransferase
RGD ID: 12270613
Description: ENCODES a protein that exhibits triglyceride lipase activity (ortholog); INVOLVED IN lipid metabolic process (ortholog); ASSOCIATED WITH autosomal recessive congenital ichthyosis 1 (ortholog); Chanarin-Dorfman syndrome (ortholog); colon adenocarcinoma (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); intracellular membrane-bounded organelle (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 1-acylglycerol-3-phosphate O-acyltransferase ABHD5; 1-acylglycerol-3-phosphate O-acyltransferase ABHD5-like; abhydrolase domain containing 5
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1232,584,813 - 2,619,204 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl232,586,678 - 2,737,583 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha232,622,390 - 2,656,835 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0232,837,297 - 2,871,778 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl232,837,304 - 2,871,784 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1232,673,959 - 2,708,185 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0232,804,668 - 2,839,064 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0232,772,747 - 2,807,406 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
ABHD5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1232,584,813 - 2,619,204 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl232,586,678 - 2,737,583 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha232,622,390 - 2,656,835 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0232,837,297 - 2,871,778 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl232,837,304 - 2,871,784 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1232,673,959 - 2,708,185 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0232,804,668 - 2,839,064 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0232,772,747 - 2,807,406 (-)NCBIUU_Cfam_GSD_1.0
ABHD5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38343,690,870 - 43,734,371 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl343,690,108 - 43,734,371 (+)EnsemblGRCh38hg38GRCh38
GRCh37343,732,362 - 43,775,863 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36343,707,379 - 43,735,296 (+)NCBINCBI36Build 36hg18NCBI36
Build 34343,707,378 - 43,735,295NCBI
Celera343,670,699 - 43,702,531 (+)NCBICelera
Cytogenetic Map3p21.33NCBI
HuRef343,775,563 - 43,807,394 (+)NCBIHuRef
CHM1_1343,682,530 - 43,714,373 (+)NCBICHM1_1
T2T-CHM13v2.0343,706,458 - 43,749,966 (+)NCBIT2T-CHM13v2.0
Abhd5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399122,180,681 - 122,210,589 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9122,180,673 - 122,210,589 (+)EnsemblGRCm39 Ensembl
GRCm389122,351,616 - 122,381,524 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9122,351,608 - 122,381,524 (+)EnsemblGRCm38mm10GRCm38
MGSCv379122,260,734 - 122,290,641 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369122,200,314 - 122,230,221 (+)NCBIMGSCv36mm8
Celera9122,816,005 - 122,845,910 (+)NCBICelera
Cytogenetic Map9F4NCBI
cM Map973.03NCBI
Abhd5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88130,877,834 - 130,903,947 (+)NCBIGRCr8
mRatBN7.28122,000,241 - 122,026,447 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8122,000,389 - 122,026,447 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8127,595,594 - 127,619,764 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08125,794,662 - 125,818,828 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08123,620,818 - 123,645,005 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08130,973,222 - 131,001,448 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8130,973,201 - 131,001,458 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08130,136,551 - 130,164,777 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48122,148,937 - 122,173,147 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18122,168,673 - 122,192,884 (+)NCBI
Celera8121,121,379 - 121,145,558 (+)NCBICelera
Cytogenetic Map8q32NCBI
Abhd5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542027,482,709 - 27,508,360 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542027,484,500 - 27,508,360 (-)NCBIChiLan1.0ChiLan1.0
ABHD5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2243,637,759 - 43,677,319 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1343,642,524 - 43,672,420 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0343,580,752 - 43,612,637 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1344,640,215 - 44,669,885 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl344,640,215 - 44,669,885 (+)Ensemblpanpan1.1panPan2
Abhd5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118199,292,423 - 199,319,725 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366951,644,581 - 1,672,117 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366951,644,758 - 1,672,024 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ABHD5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1327,006,208 - 27,056,744 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11327,006,331 - 27,053,760 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21329,834,219 - 29,881,698 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap13q12-q22NCBI
ABHD5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1225,109,699 - 5,139,021 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl225,109,765 - 5,137,673 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041162,051,858 - 162,081,174 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Abhd5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473076,414,626 - 76,436,156 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473076,414,732 - 76,436,177 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ABHD5
246 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 1 16 6 6 6 2 1 10 6
Low 4 5 6 6 4 12 7
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000007184   ⟹   ENSCAFP00000006650
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl232,586,681 - 2,607,886 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000065966   ⟹   ENSCAFP00000055486
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl232,586,681 - 2,618,785 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000076985   ⟹   ENSCAFP00000043695
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl232,586,678 - 2,737,583 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000077988   ⟹   ENSCAFP00000055988
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl232,586,678 - 2,619,109 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000087347   ⟹   ENSCAFP00000064554
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl232,586,681 - 2,618,785 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000089058   ⟹   ENSCAFP00000066647
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl232,586,681 - 2,607,520 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845035388   ⟹   ENSCAFP00845027702
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl232,837,304 - 2,871,784 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845035440   ⟹   ENSCAFP00845027741
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl232,839,477 - 2,871,784 (-)Ensembl
RefSeq Acc Id: XM_038431712   ⟹   XP_038287640
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0232,837,297 - 2,871,778 (-)NCBI
RefSeq Acc Id: XM_038507059   ⟹   XP_038362987
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1232,673,959 - 2,708,185 (-)NCBI
RefSeq Acc Id: XM_038570263   ⟹   XP_038426191
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0232,772,747 - 2,807,406 (-)NCBI
RefSeq Acc Id: XM_038634449   ⟹   XP_038490377
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0232,804,668 - 2,839,064 (-)NCBI
RefSeq Acc Id: XM_542689   ⟹   XP_542689
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1232,584,813 - 2,619,204 (-)NCBI
Dog10K_Boxer_Tasha232,622,390 - 2,656,835 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_542689   ⟸   XM_542689
- UniProtKB: A0A8C0SNT9 (UniProtKB/TrEMBL),   A0A8I3P7F2 (UniProtKB/TrEMBL),   A0A8C0JYE6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000064554   ⟸   ENSCAFT00000087347
RefSeq Acc Id: ENSCAFP00000055988   ⟸   ENSCAFT00000077988
RefSeq Acc Id: ENSCAFP00000043695   ⟸   ENSCAFT00000076985
RefSeq Acc Id: ENSCAFP00000066647   ⟸   ENSCAFT00000089058
RefSeq Acc Id: ENSCAFP00000055486   ⟸   ENSCAFT00000065966
RefSeq Acc Id: ENSCAFP00000006650   ⟸   ENSCAFT00000007184
RefSeq Acc Id: XP_038362987   ⟸   XM_038507059
RefSeq Acc Id: XP_038490377   ⟸   XM_038634449
RefSeq Acc Id: XP_038287640   ⟸   XM_038431712
- UniProtKB: A0A8C0SNT9 (UniProtKB/TrEMBL),   A0A8I3P7F2 (UniProtKB/TrEMBL),   A0A8C0JYE6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038426191   ⟸   XM_038570263
- UniProtKB: A0A8C0JYE6 (UniProtKB/TrEMBL),   A0A8C0SNT9 (UniProtKB/TrEMBL),   A0A8I3P7F2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845027741   ⟸   ENSCAFT00845035440
RefSeq Acc Id: ENSCAFP00845027702   ⟸   ENSCAFT00845035388
Protein Domains
AB hydrolase-1

Promoters
RGD ID:13687380
Promoter ID:EPDNEW_C5448
Type:initiation region
Name:ABHD5_1
Description:abhydrolase domain containing 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1232,619,131 - 2,619,191EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000004453 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030023771 UniProtKB/TrEMBL
  ENSCAFG00040014956 UniProtKB/TrEMBL
  ENSCAFG00845020085 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000007184.5 UniProtKB/TrEMBL
  ENSCAFT00000077988.2 UniProtKB/TrEMBL
  ENSCAFT00030043747.1 UniProtKB/TrEMBL
  ENSCAFT00040027583.1 UniProtKB/TrEMBL
  ENSCAFT00040027607.1 UniProtKB/TrEMBL
  ENSCAFT00845035388 ENTREZGENE
  ENSCAFT00845035388.1 UniProtKB/TrEMBL
  ENSCAFT00845035440.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1820 UniProtKB/TrEMBL
InterPro AB_hydrolase UniProtKB/TrEMBL
  AB_hydrolase_1 UniProtKB/TrEMBL
KEGG Report cfa:485570 UniProtKB/TrEMBL
NCBI Gene ABHD5 ENTREZGENE
PANTHER 1-ACYLGLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE ABHD5 UniProtKB/TrEMBL
  RE40534P-RELATED UniProtKB/TrEMBL
Pfam Abhydrolase_1 UniProtKB/TrEMBL
PRINTS ABHYDROLASE UniProtKB/TrEMBL
Superfamily-SCOP SSF53474 UniProtKB/TrEMBL
UniProt A0A8C0JYE6 ENTREZGENE
  A0A8C0SMR9_CANLF UniProtKB/TrEMBL
  A0A8C0SNT9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3P6L5_CANLF UniProtKB/TrEMBL
  A0A8I3P7F2 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:37471 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-02-04 ABHD5  abhydrolase domain containing 5, lysophosphatidic acid acyltransferase  ABHD5  abhydrolase domain containing 5  Symbol and/or name change 5135510 APPROVED