MIR487B (microRNA mir-487b) - Rat Genome Database

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Gene: MIR487B (microRNA mir-487b) Canis lupus familiaris
Analyze
Symbol: MIR487B
Name: microRNA mir-487b (Ensembl:microRNA 487b)
RGD ID: 12269691
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: cfa-mir-487b; microRNA 487b
RGD Orthologs
Human
Mouse
Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1869,275,496 - 69,275,553 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl869,275,473 - 69,275,576 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha868,793,643 - 68,793,700 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0869,557,144 - 69,557,201 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1869,220,689 - 69,220,746 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0869,286,784 - 69,286,841 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0869,684,783 - 69,684,840 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:16381832   PMID:18392026  


Genomics

Comparative Map Data
MIR487B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1869,275,496 - 69,275,553 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl869,275,473 - 69,275,576 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha868,793,643 - 68,793,700 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0869,557,144 - 69,557,201 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1869,220,689 - 69,220,746 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0869,286,784 - 69,286,841 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0869,684,783 - 69,684,840 (+)NCBIUU_Cfam_GSD_1.0
MIR487B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3814101,046,455 - 101,046,538 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl14101,046,455 - 101,046,538 (+)EnsemblGRCh38hg38GRCh38
GRCh3714101,512,792 - 101,512,875 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3614100,582,544 - 100,582,627 (+)NCBINCBI36Build 36hg18NCBI36
Celera1481,568,849 - 81,568,932 (+)NCBICelera
Cytogenetic Map14q32.31NCBI
HuRef1481,696,158 - 81,696,241 (+)NCBIHuRef
CHM1_114101,451,814 - 101,451,897 (+)NCBICHM1_1
T2T-CHM13v2.01495,281,832 - 95,281,915 (+)NCBIT2T-CHM13v2.0
Mir487b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912109,693,767 - 109,693,848 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12109,693,767 - 109,693,848 (+)EnsemblGRCm39 Ensembl
GRCm3812109,727,333 - 109,727,414 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12109,727,333 - 109,727,414 (+)EnsemblGRCm38mm10GRCm38
MGSCv3712110,965,543 - 110,965,624 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera12110,924,563 - 110,924,644 (+)NCBICelera
Cytogenetic Map12F1NCBI
cM Map1260.56NCBI
Mir487b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86134,562,890 - 134,562,971 (+)NCBIGRCr8
mRatBN7.26128,741,485 - 128,741,566 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6128,741,485 - 128,741,566 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6128,920,724 - 128,920,805 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06129,216,556 - 129,216,637 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06128,578,179 - 128,578,260 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06133,877,124 - 133,877,205 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6133,877,124 - 133,877,205 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06143,039,481 - 143,039,562 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera6126,325,864 - 126,325,945 (+)NCBICelera
Cytogenetic Map6q32NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system nervous system
High
Medium
Low
Below cutoff 1 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000034937
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl869,275,473 - 69,275,576 (+)Ensembl
RefSeq Acc Id: NR_049370
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1869,275,496 - 69,275,553 (+)NCBI
Dog10K_Boxer_Tasha868,793,643 - 68,793,700 (+)NCBI
ROS_Cfam_1.0869,557,144 - 69,557,201 (+)NCBI
UMICH_Zoey_3.1869,220,689 - 69,220,746 (+)NCBI
UNSW_CanFamBas_1.0869,286,784 - 69,286,841 (+)NCBI
UU_Cfam_GSD_1.0869,684,783 - 69,684,840 (+)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000022830 Ensembl
  ENSCAFG00845005287 ENTREZGENE
Ensembl Transcript ENSCAFT00845009419 ENTREZGENE
miRBase MI0008144 ENTREZGENE
NCBI Gene MIR487B ENTREZGENE
RNAcentral URS000015B295 RNACentral
  URS00007E3874 RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-02 MIR487B  microRNA mir-487b    microRNA 487b  Symbol and/or name change 5135510 APPROVED