CENPK (centromere protein K) - Rat Genome Database

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Gene: CENPK (centromere protein K) Canis lupus familiaris
Analyze
Symbol: CENPK
Name: centromere protein K
RGD ID: 12261994
Description: INVOLVED IN positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH castration-resistant prostate carcinoma (ortholog); genetic disease (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN inner kinetochore (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1251,262,475 - 51,300,016 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl251,263,185 - 51,292,425 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha248,192,162 - 48,256,605 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0251,727,375 - 51,792,095 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl251,753,740 - 51,783,767 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1248,787,621 - 48,852,015 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0249,576,772 - 49,641,151 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0250,468,905 - 50,533,342 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CENPK
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1251,262,475 - 51,300,016 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl251,263,185 - 51,292,425 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha248,192,162 - 48,256,605 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0251,727,375 - 51,792,095 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl251,753,740 - 51,783,767 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1248,787,621 - 48,852,015 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0249,576,772 - 49,641,151 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0250,468,905 - 50,533,342 (-)NCBIUU_Cfam_GSD_1.0
CENPK
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38565,495,624 - 65,563,168 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl565,517,766 - 65,563,168 (-)EnsemblGRCh38hg38GRCh38
GRCh37564,812,119 - 64,858,995 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36564,849,350 - 64,894,751 (-)NCBINCBI36Build 36hg18NCBI36
Celera561,812,111 - 61,857,460 (-)NCBICelera
Cytogenetic Map5q12.3ENTREZGENE
HuRef561,769,466 - 61,815,023 (-)NCBIHuRef
CHM1_1564,813,279 - 64,858,667 (-)NCBICHM1_1
T2T-CHM13v2.0566,338,058 - 66,384,928 (-)NCBIT2T-CHM13v2.0
Cenpk
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3913104,365,474 - 104,386,130 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl13104,365,119 - 104,388,900 (+)EnsemblGRCm39 Ensembl
GRCm3813104,228,611 - 104,249,622 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl13104,228,611 - 104,252,392 (+)EnsemblGRCm38mm10GRCm38
MGSCv3713105,019,035 - 105,039,697 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3613105,349,337 - 105,369,999 (+)NCBIMGSCv36mm8
Celera13108,621,358 - 108,642,051 (+)NCBICelera
Cytogenetic Map13D1NCBI
cM Map1356.42NCBI
Cenpk
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8237,094,163 - 37,155,158 (+)NCBIGRCr8
mRatBN7.2235,360,390 - 35,421,372 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl235,360,132 - 35,385,706 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx242,473,469 - 42,498,681 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0240,532,156 - 40,557,370 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0235,388,487 - 35,413,716 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0234,312,766 - 34,373,945 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl234,312,766 - 34,335,776 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0253,441,765 - 53,467,341 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4235,159,157 - 35,182,167 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1235,079,888 - 35,105,102 (+)NCBI
Celera231,336,422 - 31,359,436 (+)NCBICelera
Cytogenetic Map2q13NCBI
Cenpk
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554463,531,702 - 3,583,914 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554463,531,702 - 3,583,914 (+)NCBIChiLan1.0ChiLan1.0
CENPK
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2448,358,594 - 48,409,512 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1546,512,221 - 46,561,002 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0548,443,491 - 48,490,999 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1550,097,628 - 50,144,126 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl550,105,743 - 50,142,567 (+)Ensemblpanpan1.1panPan2
Cenpk
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213194,682,894 - 194,746,935 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364803,624,143 - 3,645,884 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364803,621,758 - 3,645,968 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CENPK
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1644,041,490 - 44,080,492 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11644,008,673 - 44,080,565 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21647,320,120 - 47,359,171 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CENPK
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1461,712,006 - 61,755,082 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl461,712,043 - 61,747,178 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604910,354,839 - 10,398,069 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cenpk
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248154,311,942 - 4,366,442 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248154,311,929 - 4,427,278 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CENPK
315 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium
Low 5 18 2 6 2 6 12 8 10 6
Below cutoff 5 4 4 4 4

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_022410063 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038459764 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038469941 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038469942 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038469943 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038530749 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038530750 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038530751 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038594973 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038594974 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038594975 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038659046 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038659048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038659049 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_847023 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000031 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSCAFT00000011837   ⟹   ENSCAFP00000010974
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl251,263,185 - 51,292,425 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000048118   ⟹   ENSCAFP00000038603
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl251,263,185 - 51,292,425 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845016937   ⟹   ENSCAFP00845013184
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl251,753,740 - 51,783,767 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845017013   ⟹   ENSCAFP00845013250
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl251,753,740 - 51,783,767 (-)Ensembl
RefSeq Acc Id: XM_022410063   ⟹   XP_022265771
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1251,262,475 - 51,300,016 (-)NCBI
Dog10K_Boxer_Tasha248,218,333 - 48,256,597 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038459764   ⟹   XP_038315692
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha248,192,162 - 48,256,605 (-)NCBI
RefSeq Acc Id: XM_038469941   ⟹   XP_038325869
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1248,813,986 - 48,852,008 (-)NCBI
RefSeq Acc Id: XM_038469942   ⟹   XP_038325870
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1248,813,986 - 48,851,248 (-)NCBI
RefSeq Acc Id: XM_038469943   ⟹   XP_038325871
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1248,787,621 - 48,852,015 (-)NCBI
RefSeq Acc Id: XM_038530749   ⟹   XP_038386677
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0250,495,065 - 50,533,335 (-)NCBI
RefSeq Acc Id: XM_038530750   ⟹   XP_038386678
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0250,495,065 - 50,532,575 (-)NCBI
RefSeq Acc Id: XM_038530751   ⟹   XP_038386679
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0250,468,905 - 50,533,342 (-)NCBI
RefSeq Acc Id: XM_038594973   ⟹   XP_038450901
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0249,603,124 - 49,641,144 (-)NCBI
RefSeq Acc Id: XM_038594974   ⟹   XP_038450902
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0249,603,124 - 49,640,384 (-)NCBI
RefSeq Acc Id: XM_038594975   ⟹   XP_038450903
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0249,576,772 - 49,641,151 (-)NCBI
RefSeq Acc Id: XM_038659046   ⟹   XP_038514974
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0251,753,747 - 51,792,088 (-)NCBI
RefSeq Acc Id: XM_038659048   ⟹   XP_038514976
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0251,753,747 - 51,791,328 (-)NCBI
RefSeq Acc Id: XM_038659049   ⟹   XP_038514977
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0251,727,375 - 51,792,095 (-)NCBI
RefSeq Acc Id: XM_847023   ⟹   XP_852116
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1251,262,475 - 51,299,974 (-)NCBI
Dog10K_Boxer_Tasha248,218,333 - 48,255,837 (-)NCBI
Sequence:
RefSeq Acc Id: XP_852116   ⟸   XM_847023
- Peptide Label: isoform X1
- UniProtKB: A0A8C0M286 (UniProtKB/TrEMBL),   A0A8I3NB51 (UniProtKB/TrEMBL),   A0A8C0Q425 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022265771   ⟸   XM_022410063
- Peptide Label: isoform X1
- UniProtKB: A0A8C0M286 (UniProtKB/TrEMBL),   A0A8I3NB51 (UniProtKB/TrEMBL),   A0A8C0Q425 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000010974   ⟸   ENSCAFT00000011837
RefSeq Acc Id: ENSCAFP00000038603   ⟸   ENSCAFT00000048118
RefSeq Acc Id: XP_038325871   ⟸   XM_038469943
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038325869   ⟸   XM_038469941
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038325870   ⟸   XM_038469942
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038450903   ⟸   XM_038594975
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038450901   ⟸   XM_038594973
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038450902   ⟸   XM_038594974
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038514977   ⟸   XM_038659049
- Peptide Label: isoform X2
- UniProtKB: A0A8C0Q425 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038514974   ⟸   XM_038659046
- Peptide Label: isoform X1
- UniProtKB: A0A8C0M286 (UniProtKB/TrEMBL),   A0A8I3NB51 (UniProtKB/TrEMBL),   A0A8C0Q425 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038514976   ⟸   XM_038659048
- Peptide Label: isoform X1
- UniProtKB: A0A8C0M286 (UniProtKB/TrEMBL),   A0A8I3NB51 (UniProtKB/TrEMBL),   A0A8C0Q425 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038315692   ⟸   XM_038459764
- Peptide Label: isoform X2
- UniProtKB: A0A8C0Q425 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038386679   ⟸   XM_038530751
- Peptide Label: isoform X2
- UniProtKB: A0A8C0Q425 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038386677   ⟸   XM_038530749
- Peptide Label: isoform X1
- UniProtKB: A0A8C0M286 (UniProtKB/TrEMBL),   A0A8C0Q425 (UniProtKB/TrEMBL),   A0A8I3NB51 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038386678   ⟸   XM_038530750
- Peptide Label: isoform X1
- UniProtKB: A0A8C0M286 (UniProtKB/TrEMBL),   A0A8C0Q425 (UniProtKB/TrEMBL),   A0A8I3NB51 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845013250   ⟸   ENSCAFT00845017013
RefSeq Acc Id: ENSCAFP00845013184   ⟸   ENSCAFT00845016937


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000007392 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030002322 UniProtKB/TrEMBL
  ENSCAFG00040002870 UniProtKB/TrEMBL
  ENSCAFG00845009602 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000011837.5 UniProtKB/TrEMBL
  ENSCAFT00000048118.4 UniProtKB/TrEMBL
  ENSCAFT00030004279.1 UniProtKB/TrEMBL
  ENSCAFT00030004295.1 UniProtKB/TrEMBL
  ENSCAFT00040005523.1 UniProtKB/TrEMBL
  ENSCAFT00845016937 ENTREZGENE
  ENSCAFT00845016937.1 UniProtKB/TrEMBL
  ENSCAFT00845017013.1 UniProtKB/TrEMBL
InterPro Centromere_CenpK UniProtKB/TrEMBL
NCBI Gene CENPK ENTREZGENE
PANTHER CENTROMERE PROTEIN K UniProtKB/TrEMBL
  PTHR14401 UniProtKB/TrEMBL
Pfam CENP-K UniProtKB/TrEMBL
UniProt A0A8C0M286 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0M948_CANLF UniProtKB/TrEMBL
  A0A8C0Q425 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NB51 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NNV9_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:39106 ENTREZGENE