POLR2B (RNA polymerase II subunit B)

Gene: POLR2B (RNA polymerase II subunit B) Canis lupus familiaris

Analyze

Symbol:

POLR2B

Name:

RNA polymerase II subunit B

RGD ID:

12260573

Description:

ENCODES a protein that exhibits chromatin binding (inferred); DNA binding (inferred); DNA-directed 5'-3' RNA polymerase activity (inferred); INVOLVED IN DNA-templated transcription (inferred); RNA-templated transcription (inferred); transcription by RNA polymerase II (inferred); PARTICIPATES IN RNA polymerase II transcription pathway; ASSOCIATED WITH genetic disease (ortholog); Tracheoesophageal Fistula (ortholog); FOUND IN chromosome, telomeric region (inferred); DNA-directed RNA polymerase complex (inferred); nucleoplasm (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

DNA-directed RNA polymerase II subunit RPB2; polymerase (RNA) II (DNA directed) polypeptide B, 140kDa

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	13	49,091,458 - 49,138,413 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	13	49,090,863 - 49,138,487 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	13	48,982,054 - 49,028,661 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	13	49,705,912 - 49,752,974 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	13	49,705,467 - 49,752,975 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	13	49,378,679 - 49,425,490 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	13	48,907,935 - 48,954,761 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	13	49,852,758 - 49,900,240 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Tracheoesophageal Fistula (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

DNA-templated transcription (IEA)

RNA-templated transcription (IEA)

transcription by RNA polymerase II (IEA)

Cellular Component

chromosome, telomeric region (IEA)

DNA-directed RNA polymerase complex (IEA)

nucleoplasm (IEA)

nucleus (IEA)

RNA polymerase II, core complex (IEA)

Molecular Function

chromatin binding (IEA)

DNA binding (IEA)

DNA-directed 5'-3' RNA polymerase activity (IEA)

metal ion binding (IEA)

nucleotidyltransferase activity (IEA)

protein binding (ISO)

ribonucleoside binding (IEA)

RNA polymerase II activity (IEA)

RNA-dependent RNA polymerase activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

RNA polymerase II transcription pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

POLR2B
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	13	49,091,458 - 49,138,413 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	13	49,090,863 - 49,138,487 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	13	48,982,054 - 49,028,661 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	13	49,705,912 - 49,752,974 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	13	49,705,467 - 49,752,975 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	13	49,378,679 - 49,425,490 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	13	48,907,935 - 48,954,761 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	13	49,852,758 - 49,900,240 (+)	NCBI		UU_Cfam_GSD_1.0

POLR2B
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	4	56,978,896 - 57,031,158 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	4	56,977,722 - 57,031,158 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	4	57,845,062 - 57,897,324 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	4	57,539,866 - 57,592,091 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	4	57,686,036 - 57,738,262	NCBI
Celera	4	55,351,060 - 55,402,358 (+)	NCBI		Celera
Cytogenetic Map	4	q12	NCBI
HuRef	4	53,798,541 - 53,850,908 (+)	NCBI		HuRef
CHM1_1	4	57,880,501 - 57,933,190 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	4	60,470,344 - 60,522,595 (+)	NCBI		T2T-CHM13v2.0

Polr2b
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	77,458,331 - 77,497,175 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	77,457,994 - 77,497,171 (+)	Ensembl		GRCm39 Ensembl
GRCm38	5	77,310,484 - 77,349,328 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	77,310,147 - 77,349,324 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	5	77,739,509 - 77,778,353 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	5	78,385,273 - 78,424,099 (+)	NCBI		MGSCv36	mm8
Celera	5	74,577,709 - 74,617,045 (+)	NCBI		Celera
Cytogenetic Map	5	C3.3	NCBI
cM Map	5	41.66	NCBI

Polr2b
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	31,151,534 - 31,189,222 (-)	NCBI		GRCr8
mRatBN7.2	14	30,797,228 - 30,834,916 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	30,797,228 - 30,834,916 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	14	31,178,151 - 31,215,766 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	32,486,476 - 32,524,093 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	30,971,132 - 31,008,749 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	33,070,104 - 33,107,792 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	33,070,078 - 33,107,776 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	14	32,863,627 - 32,901,277 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	14	33,069,966 - 33,107,615 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	14	33,069,967 - 33,107,600 (-)	NCBI
Celera	14	30,116,602 - 30,154,129 (-)	NCBI		Celera
Cytogenetic Map	14	p11	NCBI

Polr2b
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955447	14,110,182 - 14,150,556 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955447	14,110,182 - 14,150,556 (-)	NCBI	ChiLan1.0	ChiLan1.0

POLR2B
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	3	72,744,237 - 72,798,118 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	4	72,949,670 - 73,003,185 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	4	66,888,215 - 66,940,702 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	4	73,462,000 - 73,514,985 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	4	73,462,000 - 73,514,985 (-)	Ensembl	panpan1.1		panPan2

Polr2b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405285	27,179,024 - 27,225,143 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936482	19,073,124 - 19,119,421 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936482	19,073,125 - 19,119,424 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

POLR2B
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	8	56,231,789 - 56,285,011 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	8	56,232,730 - 56,283,367 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	8	59,014,262 - 59,064,755 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

POLR2B
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	7	11,694,446 - 11,736,215 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	7	11,694,619 - 11,736,611 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666066	12,273,518 - 12,305,507 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Polr2b
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624761	12,387,553 - 12,430,871 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624761	12,387,553 - 12,430,211 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in POLR2B
536 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	reproductive system	respiratory system	adipose tissue
High
Medium	4	4	16		6		6	6	12	8	10	5
Low	1	1	6	6		6						1
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_014118823	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038493881	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038556187	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038620119	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038685737	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000013	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000144	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000013	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000361	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000013	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCAFT00000003641 ⟹ ENSCAFP00000003370

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	13	49,090,863 - 49,138,487 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00000074700 ⟹ ENSCAFP00000060977

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	13	49,090,863 - 49,138,487 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00000087521 ⟹ ENSCAFP00000049302

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	13	49,090,863 - 49,138,487 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00000090830 ⟹ ENSCAFP00000044869

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	13	49,091,283 - 49,138,487 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845025195 ⟹ ENSCAFP00845019812

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	13	49,705,467 - 49,752,975 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845025283 ⟹ ENSCAFP00845019891

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	13	49,705,608 - 49,752,975 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845025300 ⟹ ENSCAFP00845019907

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	13	49,705,608 - 49,752,975 (+)	Ensembl

RefSeq Acc Id:

XM_014118823 ⟹ XP_013974298

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	13	49,091,458 - 49,138,413 (+)	NCBI
Dog10K_Boxer_Tasha	13	48,982,054 - 49,028,661 (+)	NCBI

Sequence:

show sequence

TTGGCCTCGGCCCCGAGAAGCAGAGCATTCTGGGAACGCCGGAGACGGAAATTACTTCCCCTCA
CGCTGCGGGCGCTGGTGGCTGCTGCGCGGTTTTCTCCGGTTTCAAGAGTTAGGAACTTGGGAAC
CGTCTGCCAGTATGTACGACGCGGACGAAGATATGCAATATGATGAAGATGATGATGAAATCAC
GCCAGACTTGTGGCAAGAAGCATGCTGGATTGTAATCAGTTCCTATTTTGACGAGAAAGGCTTG
GTCAGACAACAGCTGGATTCTTTTGATGAGTTTATTCAGATGTCTGTTCAAAGAATTGTGGAAG
ATGCTCCACCTATAGACCTACAAGCTGAAGCTCAGCATGCTAGTGGAGAAGTTGAAGAACCGCC
AAGATACTTGCTGAAGTTTGAACAAATTTACCTCTCCAAGCCTACCCATTGGGAAAGAGATGGT
GCTCCTTCGCCAATGATGCCAAATGAGGCCAGGTTAAGAAATCTCACGTATTCTGCTCCACTTT
ATGTTGATATAACAAAAACAGTCATTAAAGAAGGTGAAGAACAACTTCAAACTCAGCATCAGAA
AACTTTTATAGGAAAAATTCCAATTATGTTGCGTTCAACTTACTGCCTGTTGAATGGCTTAACA
GATCGTGATCTTTGTGAGTTAAATGAATGCCCTTTGGATCCTGGTGGATATTTCATTATTAATG
GATCAGAAAAGGTTCTGATTGCTCAAGAGAAAATGGCGACAAACACCGTCTATGTGTTCGCTAA
AAAGGATTCTAAATATGCCTACACAGGAGAGTGTAGATCATGTCTGGAGAATTCTTCCCGACCC
ACAAGTACTATTTGGGTTAGCATGCTGGCAAGAGGAGGACAGGGTGCAAAAAAGAGTGCTATTG
GTCAACGCATTGTGGCAACTCTACCATATATCAAGCAGGAAGTTCCCATCATTATTGTGTTTAG
AGCATTAGGTTTTGTGTCTGACAGAGATATTTTAGAGCATATTATTTATGATTTTGAAGATCCA
GAGATGATGGAAATGGTGAAACCTTCTCTCGATGAAGCTTTTGTCATCCAGGAGCAGAATGTTG
CACTAAATTTCATTGGCTCAAGAGGGGCAAAGCCTGGGGTCACTAAAGAGAAAAGAATTAAATA
TGCAAAAGAAGTCTTACAAAAAGAAATGCTCCCTCATGTTGGTGTCAGTGACTTTTGTGAGACC
AAAAAAGCTTATTTTTTGGGGTACATGGTTCATAGGTTGCTTCTAGCAGCCTTGGGTAGAAGAG
AATTAGATGACAGGGATCACTATGGAAACAAAAGATTGGATCTTGCTGGGCCACTGCTTGCATT
CTTATTTAGAGGTATGTTTAAGAATTTGCTTAAAGAAGTGCGGATCTATGCACAGAAGTTTATT
GATCGAGGAAAGGATTTTAACTTGGAGTTGGCAATTAAAACAAGGATTATATCTGATGGCCTAA
AATATTCCTTAGCTACTGGAAACTGGGGTGACCAAAAGAAAGCTCATCAAGCCAGAGCTGGAGT
ATCTCAGGTATTAAACCGCCTGACTTTTGCATCTACTCTTTCTCACCTTCGTCGTTTGAATTCA
CCTATTGGTAGAGATGGCAAGCTAGCAAAACCAAGACAGTTGCATAATACATTGTGGGGAATGG
TGTGTCCTGCTGAGACCCCAGAGGGCCATGCTGTAGGACTTGTGAAGAATTTAGCCCTGATGGC
TTATATTTCAGTTGGGTCTCAGCCTTCTCCAATTCTGGAATTTTTAGAAGAATGGAGTATGGAA
AATTTAGAAGAAATTTCTCCTGCAGCTATTGCTGATGCAACCAAGATTTTTGTTAATGGTTGCT
GGGTTGGAATACATAAAGATCCTGAACAACTTATGAACACTCTAAGGAAATTGCGGCGTCAGAT
GGACATCATTGTGTCTGAAGTTTCTATGATCAGAGATATTCGAGAGAGGGAGATTCGGATTTAT
ACAGATGCAGGCCGTATTTGTAGGCCACTTCTGATTGTAGAAAAACAAAAACTACTTTTGAAGA
AGAGACACATTGATCAGTTGAAAGAGAGAGAATATAACAACTACAGTTGGCAGGATCTTGTGGC
CAGTGGGGTAGTAGAATATATTGATACTCTGGAAGAAGAAACAGTGATGCTTGCAATGACTCCA
GATGATTTACAGGAAAAAGAAGTAGCTTATTGTTCCACATATACACACTGTGAGATTCATCCAT
CAATGATTCTTGGTGTCTGTGCATCTATTATTCCCTTTCCTGATCATAACCAGTCCCCTAGAAA
CACATATCAGTCTGCTATGGGTAAGCAGGCTATGGGAGTTTATATCACCAACTTCCACGTTCGT
ATGGATACACTGGCCCATGTTCTGTATTATCCTCAAAAACCGCTTGTGACTACACGGTCAATGG
AATATCTACGATTTAGAGAGCTTCCAGCAGGTATCAACTCCATTGTGGCCATTGCATCATACAC
TGGATATAACCAAGAAGACTCTGTTATCATGAATCGTTCAGCTGTAGACAGAGGCTTTTTCAGG
TCTGTCTTCTATCGATCATATAAAGAACAGGAATCTAAGAAAGGATTTGATCAAGAAGAAGTTT
TTGAGAAGCCAACTCGCGAAACATGCCAGGGTATGAGGCATGCCATTTATGACAAGCTGGATGA
TGATGGTTTGATAGCTCCTGGAGTCCGTGTATCAGGAGATGATGTTATTATAGGCAAAACAGTC
ACCTTGCCTGAAAATGAAGATGAATTAGAGGGCACTAATAGGCGCTATACCAAGAGAGACTGTA
GCACATTTCTTAGAACTAGTGAGACTGGCATTGTGGATCAGGTTATGGTAACTCTCAACCAGGA
AGGATATAAATTTTGTAAAATAAGGGTCCGCTCTGTTAGAATTCCACAGATTGGAGACAAATTT
GCTAGTCGACATGGTCAAAAGGGTACTTGTGGTATTCAGTACAGACAAGAGGACATGCCTTTTA
CCTGTGAGGGTATCACCCCTGATATCATCATAAATCCCCATGCCATTCCCTCTCGCATGACTAT
TGGTCACTTGATTGAATGTCTTCAAGGGAAGGTATCAGCTAACAAGGGTGAAATTGGTGATGCC
ACTCCATTTAATGATGCTGTTAACGTGCAGAAGATTTCTAATCTGTTATCTGATTATGGCTACC
ATCTCAGAGGAAATGAGGTCCTGTACAATGGTTTCACTGGTCGAAAAATCACGTCACAGATTTT
TATTGGTCCCACATATTACCAGCGTTTGAAGCATATGGTGGATGATAAGATTCATTCTCGTGCC
AGGGGACCTATTCAGATCCTTAATAGACAGCCCATGGAGGGTAGATCTCGTGATGGTGGTCTAC
GTTTTGGAGAAATGGAACGAGATTGTCAGATTGCCCATGGAGCAGCCCAGTTTTTAAGGGAAAG
ATTGTTTGAGGCGTCAGATCCATATCAGGTTCATGTCTGCAATCTTTGTGGCATAATGGCGATT
GCTAACACGAGGACCCATACATATGAATGCCGAGGCTGCCGCAATAAAACCCAGATTTCTTTGG
TGCGAATGCCTTATGCGTGCAAGCTGTTGTTTCAGGAACTTATGTCTATGAGTATTGCACCTCG
AATGATGAGTGTTTAGTTCTTTTAAAAACCTCAAGATACTTGTAAATATTTTTGTTTCTTCAGT
ATGTTTTTAAAAAAAAAAAACCACAGTGTACTGCATTGTGAGA

hide sequence

RefSeq Acc Id:

XM_038493881 ⟹ XP_038349809

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	13	49,378,679 - 49,425,490 (+)	NCBI

RefSeq Acc Id:

XM_038556187 ⟹ XP_038412115

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	13	49,852,758 - 49,900,240 (+)	NCBI

RefSeq Acc Id:

XM_038620119 ⟹ XP_038476047

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	13	48,907,935 - 48,954,761 (+)	NCBI

RefSeq Acc Id:

XM_038685737 ⟹ XP_038541665

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	13	49,705,912 - 49,752,974 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_013974298	(Get FASTA)	NCBI Sequence Viewer
	XP_038349809	(Get FASTA)	NCBI Sequence Viewer
	XP_038412115	(Get FASTA)	NCBI Sequence Viewer
	XP_038476047	(Get FASTA)	NCBI Sequence Viewer
	XP_038541665	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000003370.5
	ENSCAFP00000044869.2
	ENSCAFP00000049302.1
	ENSCAFP00030035247.1
	ENSCAFP00030035330.1
	ENSCAFP00040030467.1
	ENSCAFP00040030524.1
	ENSCAFP00845019812.1
	ENSCAFP00845019891
	ENSCAFP00845019891.1
	ENSCAFP00845019907.1

RefSeq Acc Id:

XP_013974298 ⟸ XM_014118823

- UniProtKB:

A0A8C0LYL6 (UniProtKB/TrEMBL), A0A8I3S0M4 (UniProtKB/TrEMBL), A0A8P0N5D8 (UniProtKB/TrEMBL), A0A8C0PDV4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MYDADEDMQYDEDDDEITPDLWQEACWIVISSYFDEKGLVRQQLDSFDEFIQMSVQRIVEDAPP
IDLQAEAQHASGEVEEPPRYLLKFEQIYLSKPTHWERDGAPSPMMPNEARLRNLTYSAPLYVDI
TKTVIKEGEEQLQTQHQKTFIGKIPIMLRSTYCLLNGLTDRDLCELNECPLDPGGYFIINGSEK
VLIAQEKMATNTVYVFAKKDSKYAYTGECRSCLENSSRPTSTIWVSMLARGGQGAKKSAIGQRI
VATLPYIKQEVPIIIVFRALGFVSDRDILEHIIYDFEDPEMMEMVKPSLDEAFVIQEQNVALNF
IGSRGAKPGVTKEKRIKYAKEVLQKEMLPHVGVSDFCETKKAYFLGYMVHRLLLAALGRRELDD
RDHYGNKRLDLAGPLLAFLFRGMFKNLLKEVRIYAQKFIDRGKDFNLELAIKTRIISDGLKYSL
ATGNWGDQKKAHQARAGVSQVLNRLTFASTLSHLRRLNSPIGRDGKLAKPRQLHNTLWGMVCPA
ETPEGHAVGLVKNLALMAYISVGSQPSPILEFLEEWSMENLEEISPAAIADATKIFVNGCWVGI
HKDPEQLMNTLRKLRRQMDIIVSEVSMIRDIREREIRIYTDAGRICRPLLIVEKQKLLLKKRHI
DQLKEREYNNYSWQDLVASGVVEYIDTLEEETVMLAMTPDDLQEKEVAYCSTYTHCEIHPSMIL
GVCASIIPFPDHNQSPRNTYQSAMGKQAMGVYITNFHVRMDTLAHVLYYPQKPLVTTRSMEYLR
FRELPAGINSIVAIASYTGYNQEDSVIMNRSAVDRGFFRSVFYRSYKEQESKKGFDQEEVFEKP
TRETCQGMRHAIYDKLDDDGLIAPGVRVSGDDVIIGKTVTLPENEDELEGTNRRYTKRDCSTFL
RTSETGIVDQVMVTLNQEGYKFCKIRVRSVRIPQIGDKFASRHGQKGTCGIQYRQEDMPFTCEG
ITPDIIINPHAIPSRMTIGHLIECLQGKVSANKGEIGDATPFNDAVNVQKISNLLSDYGYHLRG
NEVLYNGFTGRKITSQIFIGPTYYQRLKHMVDDKIHSRARGPIQILNRQPMEGRSRDGGLRFGE
MERDCQIAHGAAQFLRERLFEASDPYQVHVCNLCGIMAIANTRTHTYECRGCRNKTQISLVRMP
YACKLLFQELMSMSIAPRMMSV

hide sequence

RefSeq Acc Id:

ENSCAFP00000060977 ⟸ ENSCAFT00000074700

RefSeq Acc Id:

ENSCAFP00000049302 ⟸ ENSCAFT00000087521

RefSeq Acc Id:

ENSCAFP00000003370 ⟸ ENSCAFT00000003641

RefSeq Acc Id:

ENSCAFP00000044869 ⟸ ENSCAFT00000090830

RefSeq Acc Id:

XP_038349809 ⟸ XM_038493881

RefSeq Acc Id:

XP_038476047 ⟸ XM_038620119

RefSeq Acc Id:	XP_038541665 ⟸ XM_038685737
- UniProtKB:	A0A8C0LYL6 (UniProtKB/TrEMBL), A0A8I3S0M4 (UniProtKB/TrEMBL), A0A8P0N5D8 (UniProtKB/TrEMBL), A0A8C0PDV4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038412115 ⟸ XM_038556187
- UniProtKB:	A0A8C0LYL6 (UniProtKB/TrEMBL), A0A8C0PDV4 (UniProtKB/TrEMBL), A0A8I3S0M4 (UniProtKB/TrEMBL), A0A8P0N5D8 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCAFP00845019812 ⟸ ENSCAFT00845025195

RefSeq Acc Id:

ENSCAFP00845019891 ⟸ ENSCAFT00845025283

RefSeq Acc Id:

ENSCAFP00845019907 ⟸ ENSCAFT00845025300

Protein Domains

DNA-directed RNA polymerase subunit 2 hybrid- RNA polymerase beta subunit protrusion RNA polymerase Rpb2

Promoters

RGD ID:

13685665

Promoter ID:

EPDNEW_C3733

Type:

multiple initiation site

Name:

POLR2B_1

Description:

RNA polymerase II subunit B

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	13	49,091,511 - 49,091,571	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000002296	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030021853	UniProtKB/TrEMBL
	ENSCAFG00040018724	UniProtKB/TrEMBL
	ENSCAFG00845014082	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000003641.5	UniProtKB/TrEMBL
	ENSCAFT00000087521.2	UniProtKB/TrEMBL
	ENSCAFT00000090830.2	UniProtKB/TrEMBL
	ENSCAFT00030040384.1	UniProtKB/TrEMBL
	ENSCAFT00030040475.1	UniProtKB/TrEMBL
	ENSCAFT00040034996.1	UniProtKB/TrEMBL
	ENSCAFT00040035059.1	UniProtKB/TrEMBL
	ENSCAFT00845025195.1	UniProtKB/TrEMBL
	ENSCAFT00845025283	ENTREZGENE
	ENSCAFT00845025283.1	UniProtKB/TrEMBL
	ENSCAFT00845025300.1	UniProtKB/TrEMBL
Gene3D-CATH	2.40.270.10	UniProtKB/TrEMBL
	2.40.50.150	UniProtKB/TrEMBL
	3.90.1070.20	UniProtKB/TrEMBL
	3.90.1100.10	UniProtKB/TrEMBL
	3.90.1110.10	UniProtKB/TrEMBL
	RNA polymerase alpha subunit dimerisation domain	UniProtKB/TrEMBL
InterPro	DNA-dir_RNA_pol_su2	UniProtKB/TrEMBL
	DNA-dir_RNAP_su2_dom	UniProtKB/TrEMBL
	DNA-dir_RNAP_su2_hyb_sf	UniProtKB/TrEMBL
	RNA_pol_bsu_CS	UniProtKB/TrEMBL
	RNA_pol_bsu_protrusion	UniProtKB/TrEMBL
	RNA_pol_Rpb2_2	UniProtKB/TrEMBL
	RNA_pol_Rpb2_2_sf	UniProtKB/TrEMBL
	RNA_pol_Rpb2_3	UniProtKB/TrEMBL
	RNA_pol_Rpb2_4	UniProtKB/TrEMBL
	RNA_pol_Rpb2_5	UniProtKB/TrEMBL
	RNA_pol_Rpb2_7	UniProtKB/TrEMBL
	RNA_pol_RPB2_OB-fold	UniProtKB/TrEMBL
KEGG Report	cfa:475152	UniProtKB/TrEMBL
NCBI Gene	POLR2B	ENTREZGENE
PANTHER	DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2	UniProtKB/TrEMBL
	PTHR20856	UniProtKB/TrEMBL
Pfam	RNA_pol_Rpb2_1	UniProtKB/TrEMBL
	RNA_pol_Rpb2_2	UniProtKB/TrEMBL
	RNA_pol_Rpb2_3	UniProtKB/TrEMBL
	RNA_pol_Rpb2_4	UniProtKB/TrEMBL
	RNA_pol_Rpb2_5	UniProtKB/TrEMBL
	RNA_pol_Rpb2_6	UniProtKB/TrEMBL
	RNA_pol_Rpb2_7	UniProtKB/TrEMBL
PROSITE	RNA_POL_BETA	UniProtKB/TrEMBL
Superfamily-SCOP	beta and beta-prime subunits of DNA dependent RNA-polymerase	UniProtKB/TrEMBL
UniProt	A0A8C0LYL6	ENTREZGENE
	A0A8C0PDV4	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0T3M2_CANLF	UniProtKB/TrEMBL
	A0A8I3NPE6_CANLF	UniProtKB/TrEMBL
	A0A8I3NSE9_CANLF	UniProtKB/TrEMBL
	A0A8I3S0M4	ENTREZGENE, UniProtKB/TrEMBL
	A0A8P0N5D8	ENTREZGENE, UniProtKB/TrEMBL
	A0A8P0NV71_CANLF	UniProtKB/TrEMBL
	A0A8P0NZ93_CANLF	UniProtKB/TrEMBL
VGNC ID	VGNC:44793	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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