F8A1 (coagulation factor VIII associated 1) - Rat Genome Database

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Gene: F8A1 (coagulation factor VIII associated 1) Canis lupus familiaris
Analyze
Symbol: F8A1
Name: coagulation factor VIII associated 1
RGD ID: 12259810
Description: INVOLVED IN negative regulation of proteasomal protein catabolic process (ortholog); ASSOCIATED WITH adrenoleukodystrophy (ortholog); autistic disorder (ortholog); Barth syndrome (ortholog); FOUND IN cytoplasm (ortholog); early endosome (ortholog); nuclear body (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: coagulation factor VIII-associated 1
RGD Orthologs
Human
Mouse
Bonobo
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X122,914,362 - 122,916,199 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX107,907,633 - 107,909,602 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X126,041,939 - 126,043,898 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1X121,789,672 - 121,791,624 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X124,311,803 - 124,313,752 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X124,005,006 - 124,006,822 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
F8A1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X122,914,362 - 122,916,199 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX107,907,633 - 107,909,602 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X126,041,939 - 126,043,898 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1X121,789,672 - 121,791,624 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X124,311,803 - 124,313,752 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X124,005,006 - 124,006,822 (+)NCBIUU_Cfam_GSD_1.0
F8A2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X155,382,095 - 155,383,801 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX155,382,095 - 155,383,801 (+)EnsemblGRCh38hg38GRCh38
GRCh37X154,611,744 - 154,613,450 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X154,264,958 - 154,266,073 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X154,250,849 - 154,251,965NCBI
CeleraX154,273,269 - 154,274,384 (+)NCBICelera
Cytogenetic MapXq28NCBI
HuRefX143,156,680 - 143,157,295 (+)NCBIHuRef
CHM1_1X153,983,222 - 153,984,337 (+)NCBICHM1_1
T2T-CHM13v2.0X153,620,102 - 153,621,808 (+)NCBIT2T-CHM13v2.0
F8a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X72,271,912 - 72,274,401 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX72,271,897 - 72,274,401 (+)EnsemblGRCm39 Ensembl
GRCm38X73,228,306 - 73,230,795 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX73,228,291 - 73,230,795 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X70,473,645 - 70,476,134 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X69,481,026 - 69,483,515 (+)NCBIMGSCv36mm8
CeleraX64,133,669 - 64,136,158 (+)NCBICelera
Cytogenetic MapXA7.3NCBI
cM MapX37.29NCBI
LOC100985575
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X155,350,477 - 155,352,160 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X155,354,085 - 155,355,766 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X144,851,466 - 144,853,185 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3

Variants

.
Variants in F8A1
4 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 4 4 19 4 4 4 5 5 11 1 9 5
Low 1 1 3 2 2 2 1 1 1 7 1 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: XM_038448906   ⟹   XP_038304834
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0X126,041,939 - 126,043,898 (+)NCBI
RefSeq Acc Id: XM_038464321   ⟹   XP_038320249
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_TashaX107,907,633 - 107,909,602 (+)NCBI
RefSeq Acc Id: XM_038524808   ⟹   XP_038380736
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1X121,789,672 - 121,791,624 (+)NCBI
RefSeq Acc Id: XM_038586687   ⟹   XP_038442615
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0X124,005,006 - 124,006,822 (+)NCBI
RefSeq Acc Id: XM_038650870   ⟹   XP_038506798
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0X124,311,803 - 124,313,752 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_038380736   ⟸   XM_038524808
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038506798   ⟸   XM_038650870
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038304834   ⟸   XM_038448906
- Peptide Label: isoform X1
- UniProtKB: A0A8C0K6U9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038320249   ⟸   XM_038464321
- Peptide Label: isoform X1
- UniProtKB: A0A8C0K6U9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038442615   ⟸   XM_038586687
- Peptide Label: isoform X3


Additional Information

Database Acc Id Source(s)
NCBI Gene F8A1 ENTREZGENE
UniProt A0A8C0K6U9 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-05-16 F8A1  coagulation factor VIII associated 1    coagulation factor VIII-associated 1  Symbol and/or name change 5135510 APPROVED