SEC14L1 (SEC14 like lipid binding 1) - Rat Genome Database

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Gene: SEC14L1 (SEC14 like lipid binding 1) Canis lupus familiaris
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Symbol: SEC14L1
Name: SEC14 like lipid binding 1
RGD ID: 12258813
Description: ENCODES a protein that exhibits protein sequestering activity (inferred); RIG-I binding (inferred); INVOLVED IN choline transport (inferred); negative regulation of RIG-I signaling pathway (inferred); ASSOCIATED WITH genetic disease (ortholog); Monoclonal B-Cell Lymphocytosis (ortholog); FOUND IN cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: SEC14-like 1; SEC14-like protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.193,683,328 - 3,740,271 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl93,659,451 - 3,739,213 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha94,365,609 - 4,422,239 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.094,360,709 - 4,417,642 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl94,360,714 - 4,417,622 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.194,384,488 - 4,441,395 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.094,505,242 - 4,562,080 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.094,587,564 - 4,644,483 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA,ISO)
cytosol  (IEA)
Golgi apparatus  (IEA)
nucleoplasm  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
SEC14L1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.193,683,328 - 3,740,271 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl93,659,451 - 3,739,213 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha94,365,609 - 4,422,239 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.094,360,709 - 4,417,642 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl94,360,714 - 4,417,622 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.194,384,488 - 4,441,395 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.094,505,242 - 4,562,080 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.094,587,564 - 4,644,483 (-)NCBIUU_Cfam_GSD_1.0
SEC14L1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381777,088,685 - 77,217,101 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1777,088,749 - 77,217,101 (+)EnsemblGRCh38hg38GRCh38
GRCh371775,084,767 - 75,213,183 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361772,648,647 - 72,724,778 (+)NCBINCBI36Build 36hg18NCBI36
Build 341772,648,616 - 72,724,774NCBI
Celera1771,732,575 - 71,808,664 (+)NCBICelera
Cytogenetic Map17q25.2-q25.3NCBI
HuRef1770,511,931 - 70,641,030 (+)NCBIHuRef
CHM1_11775,149,639 - 75,278,075 (+)NCBICHM1_1
T2T-CHM13v2.01777,981,537 - 78,110,663 (+)NCBIT2T-CHM13v2.0
Sec14l1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911117,005,994 - 117,050,094 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11117,005,994 - 117,050,094 (+)EnsemblGRCm39 Ensembl
GRCm3811117,115,168 - 117,159,268 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11117,115,168 - 117,159,268 (+)EnsemblGRCm38mm10GRCm38
MGSCv3711116,976,486 - 117,020,582 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611116,931,339 - 116,975,311 (+)NCBIMGSCv36mm8
Celera11128,859,607 - 128,903,470 (+)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1181.99NCBI
Sec14l1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr810102,818,693 - 102,865,841 (+)NCBIGRCr8
mRatBN7.210102,319,920 - 102,367,070 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl10102,319,920 - 102,367,068 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx10107,422,983 - 107,470,216 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.010106,886,082 - 106,933,320 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.010102,240,737 - 102,287,882 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.010106,065,712 - 106,112,859 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10106,065,712 - 106,112,857 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010105,718,075 - 105,765,282 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410107,220,734 - 107,267,940 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera10100,886,819 - 100,933,978 (+)NCBICelera
Cytogenetic Map10q32.2NCBI
Sec14l1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555065,158,805 - 5,232,551 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555065,159,090 - 5,231,827 (-)NCBIChiLan1.0ChiLan1.0
SEC14L1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21993,194,000 - 93,269,776 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11798,023,131 - 98,098,962 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01771,221,870 - 71,297,142 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11776,730,168 - 76,857,856 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1776,785,559 - 76,857,848 (+)Ensemblpanpan1.1panPan2
Sec14l1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244056024,303,778 - 4,363,669 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365942,048,054 - 2,100,859 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365942,048,146 - 2,100,808 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SEC14L1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl124,441,114 - 4,489,081 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1124,439,045 - 4,489,078 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2124,186,754 - 4,236,079 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SEC14L1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11644,490,927 - 44,565,922 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1644,489,852 - 44,565,853 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607715,216,709 - 15,293,938 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sec14l1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248016,890,134 - 6,945,443 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248016,890,278 - 6,942,724 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SEC14L1
451 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 5 22 6 6 6 6 6 12 8 10 6
Low
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_022422693 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022422694 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038484831 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038484832 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038546501 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038546502 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038610500 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038610501 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038675620 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038675621 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_540457 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000090 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000103 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000313 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSCAFT00000030383   ⟹   ENSCAFP00000028230
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl93,683,334 - 3,739,213 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000080687   ⟹   ENSCAFP00000045750
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl93,684,811 - 3,739,213 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000087955   ⟹   ENSCAFP00000052570
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl93,683,334 - 3,715,714 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000092314   ⟹   ENSCAFP00000046653
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl93,659,451 - 3,739,213 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845028078   ⟹   ENSCAFP00845022091
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl94,360,714 - 4,417,622 (-)Ensembl
RefSeq Acc Id: XM_022422693   ⟹   XP_022278401
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.193,683,328 - 3,740,271 (-)NCBI
Dog10K_Boxer_Tasha94,365,609 - 4,422,239 (-)NCBI
Sequence:
RefSeq Acc Id: XM_022422694   ⟹   XP_022278402
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.193,683,328 - 3,740,257 (-)NCBI
Dog10K_Boxer_Tasha94,365,609 - 4,422,208 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038484831   ⟹   XP_038340759
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.194,384,488 - 4,441,395 (-)NCBI
RefSeq Acc Id: XM_038484832   ⟹   XP_038340760
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.194,384,488 - 4,441,364 (-)NCBI
RefSeq Acc Id: XM_038546501   ⟹   XP_038402429
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.094,587,564 - 4,644,483 (-)NCBI
RefSeq Acc Id: XM_038546502   ⟹   XP_038402430
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.094,587,564 - 4,644,452 (-)NCBI
RefSeq Acc Id: XM_038610500   ⟹   XP_038466428
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.094,505,242 - 4,562,080 (-)NCBI
RefSeq Acc Id: XM_038610501   ⟹   XP_038466429
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.094,505,242 - 4,562,049 (-)NCBI
RefSeq Acc Id: XM_038675620   ⟹   XP_038531548
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.094,360,709 - 4,417,642 (-)NCBI
RefSeq Acc Id: XM_038675621   ⟹   XP_038531549
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.094,360,709 - 4,417,611 (-)NCBI
RefSeq Acc Id: XP_022278401   ⟸   XM_022422693
- UniProtKB: A0A8C0M130 (UniProtKB/TrEMBL),   A0A8C0K1K0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022278402   ⟸   XM_022422694
- UniProtKB: A0A8C0M130 (UniProtKB/TrEMBL),   A0A8C0K1K0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000028230   ⟸   ENSCAFT00000030383
RefSeq Acc Id: ENSCAFP00000052570   ⟸   ENSCAFT00000087955
RefSeq Acc Id: ENSCAFP00000046653   ⟸   ENSCAFT00000092314
RefSeq Acc Id: ENSCAFP00000045750   ⟸   ENSCAFT00000080687
RefSeq Acc Id: XP_038340759   ⟸   XM_038484831
RefSeq Acc Id: XP_038340760   ⟸   XM_038484832
RefSeq Acc Id: XP_038466428   ⟸   XM_038610500
RefSeq Acc Id: XP_038466429   ⟸   XM_038610501
RefSeq Acc Id: XP_038531548   ⟸   XM_038675620
- UniProtKB: A0A8C0M130 (UniProtKB/TrEMBL),   A0A8C0K1K0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038531549   ⟸   XM_038675621
- UniProtKB: A0A8C0M130 (UniProtKB/TrEMBL),   A0A8C0K1K0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038402429   ⟸   XM_038546501
- UniProtKB: A0A8C0K1K0 (UniProtKB/TrEMBL),   A0A8C0M130 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038402430   ⟸   XM_038546502
- UniProtKB: A0A8C0K1K0 (UniProtKB/TrEMBL),   A0A8C0M130 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845022091   ⟸   ENSCAFT00845028078
Protein Domains
CRAL-TRIO   GOLD   PRELI/MSF1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000005176 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030002027 UniProtKB/TrEMBL
  ENSCAFG00040004723 UniProtKB/TrEMBL
  ENSCAFG00845015759 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000080687.2 UniProtKB/TrEMBL
  ENSCAFT00000087955.2 UniProtKB/TrEMBL
  ENSCAFT00030003718.1 UniProtKB/TrEMBL
  ENSCAFT00030003749.1 UniProtKB/TrEMBL
  ENSCAFT00030003775.1 UniProtKB/TrEMBL
  ENSCAFT00030003796.1 UniProtKB/TrEMBL
  ENSCAFT00030003828.1 UniProtKB/TrEMBL
  ENSCAFT00030003867.1 UniProtKB/TrEMBL
  ENSCAFT00040008903.1 UniProtKB/TrEMBL
  ENSCAFT00040009002.1 UniProtKB/TrEMBL
  ENSCAFT00040009080.1 UniProtKB/TrEMBL
  ENSCAFT00040009153.1 UniProtKB/TrEMBL
  ENSCAFT00040009249.1 UniProtKB/TrEMBL
  ENSCAFT00040009322.1 UniProtKB/TrEMBL
  ENSCAFT00040009367.1 UniProtKB/TrEMBL
  ENSCAFT00845028078 ENTREZGENE
  ENSCAFT00845028078.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.525.10 UniProtKB/TrEMBL
  GOLD domain UniProtKB/TrEMBL
InterPro CRAL-TRIO_dom UniProtKB/TrEMBL
  CRAL-TRIO_dom_sf UniProtKB/TrEMBL
  CRAL/TRIO_N_dom UniProtKB/TrEMBL
  CRAL/TRIO_N_dom_sf UniProtKB/TrEMBL
  GOLD_dom UniProtKB/TrEMBL
  GOLD_dom_sf UniProtKB/TrEMBL
  PRELI/MSF1_dom UniProtKB/TrEMBL
NCBI Gene SEC14L1 ENTREZGENE
PANTHER SEC14 RELATED PROTEIN UniProtKB/TrEMBL
  SEC14-LIKE PROTEIN 1 UniProtKB/TrEMBL
Pfam CRAL_TRIO UniProtKB/TrEMBL
  CRAL_TRIO_N UniProtKB/TrEMBL
  PRELI UniProtKB/TrEMBL
PROSITE CRAL_TRIO UniProtKB/TrEMBL
  GOLD UniProtKB/TrEMBL
  PRELI_MSF1 UniProtKB/TrEMBL
SMART CRAL_TRIO_N UniProtKB/TrEMBL
  SEC14 UniProtKB/TrEMBL
Superfamily-SCOP SSF101576 UniProtKB/TrEMBL
  SSF46938 UniProtKB/TrEMBL
  SSF52087 UniProtKB/TrEMBL
UniProt A0A8C0K1K0 ENTREZGENE
  A0A8C0M130 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0M335_CANLF UniProtKB/TrEMBL
  A0A8C0M3C9_CANLF UniProtKB/TrEMBL
  A0A8C0M3G0_CANLF UniProtKB/TrEMBL
  A0A8C0M8A0_CANLF UniProtKB/TrEMBL
  A0A8C0Q7B4_CANLF UniProtKB/TrEMBL
  A0A8C0Q8R6_CANLF UniProtKB/TrEMBL
  A0A8C0QA48_CANLF UniProtKB/TrEMBL
  A0A8C0RXX1_CANLF UniProtKB/TrEMBL
  A0A8C0RY53_CANLF UniProtKB/TrEMBL
  A0A8I3NYM0_CANLF UniProtKB/TrEMBL
  A0A8P0P299_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:45963 ENTREZGENE