MRPL40 (mitochondrial ribosomal protein L40) - Rat Genome Database

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Gene: MRPL40 (mitochondrial ribosomal protein L40) Canis lupus familiaris
Analyze
Symbol: MRPL40
Name: mitochondrial ribosomal protein L40
RGD ID: 12253854
Description: ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); chromosome 22q11.2 deletion syndrome, distal (ortholog); FOUND IN nucleolus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 39S ribosomal protein L40, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12629,773,397 - 29,777,104 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2629,773,403 - 29,777,073 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2629,728,768 - 29,732,471 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02631,175,195 - 31,178,901 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12629,222,488 - 29,226,191 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02628,847,911 - 28,851,612 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02629,934,840 - 29,938,543 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
MRPL40
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12629,773,397 - 29,777,104 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2629,773,403 - 29,777,073 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2629,728,768 - 29,732,471 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02631,175,195 - 31,178,901 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12629,222,488 - 29,226,191 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02628,847,911 - 28,851,612 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02629,934,840 - 29,938,543 (-)NCBIUU_Cfam_GSD_1.0
MRPL40
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382219,432,545 - 19,436,075 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2219,432,545 - 19,436,075 (+)EnsemblGRCh38hg38GRCh38
GRCh372219,420,068 - 19,423,598 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362217,800,036 - 17,803,598 (+)NCBINCBI36Build 36hg18NCBI36
Build 342217,794,589 - 17,798,148NCBI
Celera223,272,293 - 3,275,855 (+)NCBICelera
Cytogenetic Map22q11.21NCBI
HuRef223,040,849 - 3,044,411 (+)NCBIHuRef
CHM1_12219,419,610 - 19,423,172 (+)NCBICHM1_1
T2T-CHM13v2.02219,809,376 - 19,812,906 (+)NCBIT2T-CHM13v2.0
Mrpl40
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391618,690,767 - 18,695,875 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1618,690,768 - 18,695,612 (-)EnsemblGRCm39 Ensembl
GRCm381618,872,018 - 18,876,637 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1618,872,018 - 18,876,862 (-)EnsemblGRCm38mm10GRCm38
MGSCv371618,872,111 - 18,876,730 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361618,785,780 - 18,790,200 (-)NCBIMGSCv36mm8
Celera1619,446,075 - 19,450,694 (-)NCBICelera
Cytogenetic Map16A3NCBI
cM Map1611.69NCBI
Mrpl40
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81195,637,751 - 95,643,587 (+)NCBIGRCr8
mRatBN7.21182,133,398 - 82,139,234 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1182,133,398 - 82,139,233 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1190,862,860 - 90,868,698 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01183,524,080 - 83,529,918 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01182,577,348 - 82,583,186 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01186,276,616 - 86,282,452 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1186,276,616 - 86,282,451 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01189,378,582 - 89,384,418 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1180,914,027 - 80,919,719 (+)NCBICelera
Cytogenetic Map11q23NCBI
Mrpl40
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544218,577,952 - 18,580,517 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544218,578,107 - 18,580,517 (-)NCBIChiLan1.0ChiLan1.0
MRPL40
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22329,057,340 - 29,061,018 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12231,604,620 - 31,608,737 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0222,191,187 - 2,195,350 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12217,865,992 - 17,870,539 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2217,866,322 - 17,870,539 (+)Ensemblpanpan1.1panPan2
Mrpl40
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118139,369,421 - 139,373,206 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366193,380,335 - 3,384,600 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366193,380,957 - 3,384,567 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MRPL40
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1451,102,613 - 51,105,767 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11451,102,900 - 51,105,769 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21454,669,933 - 54,672,802 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MRPL40
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1196,319,745 - 6,323,955 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl196,319,263 - 6,323,799 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666085610,117 - 613,937 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mrpl40
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474796,418 - 100,913 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474796,411 - 99,490 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in MRPL40
52 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 5 22 6 6 6 6 6 12 8 10 6
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000023200   ⟹   ENSCAFP00000021543
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2629,773,403 - 29,777,073 (-)Ensembl
RefSeq Acc Id: XM_038437536   ⟹   XP_038293464
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02631,175,195 - 31,178,901 (-)NCBI
RefSeq Acc Id: XM_038512400   ⟹   XP_038368328
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12629,222,488 - 29,226,191 (-)NCBI
RefSeq Acc Id: XM_038575901   ⟹   XP_038431829
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02629,934,840 - 29,938,543 (-)NCBI
RefSeq Acc Id: XM_038640112   ⟹   XP_038496040
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02628,847,911 - 28,851,612 (-)NCBI
RefSeq Acc Id: XM_534762   ⟹   XP_534762
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12629,773,397 - 29,777,104 (-)NCBI
Dog10K_Boxer_Tasha2629,728,768 - 29,732,471 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_534762   ⟸   XM_534762
- UniProtKB: A0A8P0PFV3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000021543   ⟸   ENSCAFT00000023200
RefSeq Acc Id: XP_038368328   ⟸   XM_038512400
RefSeq Acc Id: XP_038496040   ⟸   XM_038640112
RefSeq Acc Id: XP_038293464   ⟸   XM_038437536
- UniProtKB: A0A8I3Q6S0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038431829   ⟸   XM_038575901
- UniProtKB: A0A8P0PFV3 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000014614 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030021173 UniProtKB/TrEMBL
  ENSCAFG00040023231 UniProtKB/TrEMBL
  ENSCAFG00845029562 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000023200.5 UniProtKB/TrEMBL
  ENSCAFT00000097723.1 UniProtKB/TrEMBL
  ENSCAFT00030038854.1 UniProtKB/TrEMBL
  ENSCAFT00040043150.1 UniProtKB/TrEMBL
  ENSCAFT00845052345 ENTREZGENE
  ENSCAFT00845052345.1 UniProtKB/TrEMBL
  ENSCAFT00845052352.1 UniProtKB/TrEMBL
Gene3D-CATH 6.10.250.3440 UniProtKB/TrEMBL
InterPro MRPL40 UniProtKB/TrEMBL
  Ribosomal_L28/L40_mit UniProtKB/TrEMBL
KEGG Report cfa:477567 UniProtKB/TrEMBL
NCBI Gene MRPL40 ENTREZGENE
PANTHER 39S RIBOSOMAL PROTEIN L40, MITOCHONDRIAL UniProtKB/TrEMBL
  PTHR13359 UniProtKB/TrEMBL
Pfam MRP-L28 UniProtKB/TrEMBL
UniProt A0A8C0TLZ7_CANLF UniProtKB/TrEMBL
  A0A8I3Q6S0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3Q7R4_CANLF UniProtKB/TrEMBL
  A0A8P0PFV3 ENTREZGENE, UniProtKB/TrEMBL