OR6N1 (olfactory receptor family 6 subfamily N member 1)

Gene: OR6N1 (olfactory receptor family 6 subfamily N member 1) Canis lupus familiaris

Analyze

Symbol:

OR6N1

Name:

olfactory receptor family 6 subfamily N member 1

RGD ID:

12252613

Description:

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

Type:

protein-coding

RefSeq Status:

INFERRED

Previously known as:

cOR6N1; olfactory receptor OR16E08; olfactory receptor, family 6, subfamily N, member 1; OR16E08

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	38	22,993,596 - 22,994,546 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	38	22,993,596 - 22,994,546 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	38	23,008,889 - 23,009,839 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	38	23,119,082 - 23,120,032 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	38	23,119,082 - 23,120,032 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	38	22,883,018 - 22,883,968 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	38	23,417,142 - 23,418,092 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	38	23,847,933 - 23,848,883 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autoimmune interstitial lung, joint, and kidney disease (ISO)

gastrointestinal stromal tumor (ISO)

genetic disease (ISO)

parathyroid carcinoma (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

detection of chemical stimulus involved in sensory perception of smell (IBA,IEA)

G protein-coupled receptor signaling pathway (IEA)

sensory perception of smell (IEA)

Cellular Component

membrane (IEA)

plasma membrane (IBA,IEA)

Molecular Function

G protein-coupled receptor activity (IEA)

olfactory receptor activity (IBA,IEA)

References

Additional References at PubMed

PMID:14659017	PMID:14962662	PMID:21846747	PMID:22301074

Genomics

Comparative Map Data

OR6N1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	38	22,993,596 - 22,994,546 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	38	22,993,596 - 22,994,546 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	38	23,008,889 - 23,009,839 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	38	23,119,082 - 23,120,032 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	38	23,119,082 - 23,120,032 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	38	22,883,018 - 22,883,968 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	38	23,417,142 - 23,418,092 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	38	23,847,933 - 23,848,883 (+)	NCBI		UU_Cfam_GSD_1.0

OR6N1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	158,764,236 - 158,840,396 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	158,747,814 - 158,772,195 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	158,734,026 - 158,741,985 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	157,002,158 - 157,003,096 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	155,548,606 - 155,549,545	NCBI
Celera	1	131,805,908 - 131,806,846 (-)	NCBI		Celera
Cytogenetic Map	1	q23.1	NCBI
HuRef	1	130,092,821 - 130,093,759 (-)	NCBI		HuRef
CHM1_1	1	160,132,213 - 160,133,151 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	157,901,319 - 157,977,489 (-)	NCBI		T2T-CHM13v2.0

Or6n1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	173,916,604 - 173,917,546 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	173,911,897 - 173,918,909 (+)	Ensembl		GRCm39 Ensembl
GRCm38	1	174,089,038 - 174,089,980 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	174,084,331 - 174,091,343 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	176,019,169 - 176,020,111 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	175,925,717 - 175,926,655 (+)	NCBI		MGSCv36	mm8
Celera	1	181,167,198 - 181,168,140 (+)	NCBI		Celera
Cytogenetic Map	1	H3	NCBI
cM Map	1	80.89	NCBI

Or6n1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	88,639,245 - 88,640,183 (+)	NCBI		GRCr8
mRatBN7.2	13	86,106,912 - 86,107,850 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	86,102,080 - 86,108,363 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	13	88,611,802 - 88,612,740 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	90,012,082 - 90,013,020 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	87,196,815 - 87,197,753 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	92,167,643 - 92,168,581 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	92,167,643 - 92,168,581 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	13	96,685,799 - 96,686,737 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	89,843,841 - 89,844,779 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	13	90,032,724 - 90,033,663 (+)	NCBI
Celera	13	85,709,674 - 85,710,612 (+)	NCBI		Celera
Cytogenetic Map	13	q24	NCBI

LOC102028949
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955468	10,633,532 - 10,634,470 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955468	10,633,532 - 10,634,470 (-)	NCBI	ChiLan1.0	ChiLan1.0

LOC100980196
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	91,080,476 - 91,081,414 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	90,824,373 - 90,825,311 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	134,125,010 - 134,126,024 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	137,916,168 - 137,917,182 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	137,916,230 - 137,917,168 (-)	Ensembl	panpan1.1		panPan2

LOC101972437
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	5,135,136 - 5,136,088 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936740	1,618,436 - 1,619,374 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936740	1,618,422 - 1,619,374 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LOC100156472
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	4	91,476,621 - 91,501,070 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	99,491,735 - 99,492,673 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Variants

Variants in OR6N1
12 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	endocrine system	nervous system	reproductive system
High
Medium
Low
Below cutoff	2	1	1

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001313868	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000038	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AJ431539	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY356043	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000364	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000087	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000370	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JF733501	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000038	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCAFT00000018531 ⟹ ENSCAFP00000017164

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	38	22,993,596 - 22,994,546 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845028452 ⟹ ENSCAFP00845022380

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	38	23,119,082 - 23,120,032 (+)	Ensembl

RefSeq Acc Id:

NM_001313868 ⟹ NP_001300797

RefSeq Status:

INFERRED

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	38	22,993,596 - 22,994,546 (+)	NCBI
Dog10K_Boxer_Tasha	38	23,008,889 - 23,009,839 (+)	NCBI
ROS_Cfam_1.0	38	23,119,082 - 23,120,032 (+)	NCBI
UMICH_Zoey_3.1	38	22,883,018 - 22,883,968 (+)	NCBI
UNSW_CanFamBas_1.0	38	23,417,142 - 23,418,092 (+)	NCBI
UU_Cfam_GSD_1.0	38	23,847,933 - 23,848,883 (+)	NCBI

Sequence:

show sequence

ATGAGTGGTGAGCCATGGACCCCCGGGAACTGGAGCTGGGTGACAGAGTTCATCATCTTGGGCT
TTCCTCATGTCCAGGGGGTGCAGGCTTACCTCTTCGTCTTGCTACTTCTCATTTACGTCACCAC
CGTCCTGGGAAACCTGCTGATATTCCTGGTGGTGCGCCTGGACCCCCGGCTCCACACTCCCATG
TACCACTTTGTCAGCGCGCTCTCGCTGCTGGAGCTCGGCTATACAGCGGCCACCATCCCCAAGA
TGCTGTCGAACCTGCTCAGCGAGGAGAAGACCATTTCCTTCTCCGGATGCCTTCTGCAAATCTA
TTTCTTTCACTCTCTTGGGGCTGCTGAGTGCTACCTCCTCACAGCCATGGCTTATGACAGGTAC
TTAGCCATCTGCCAGCCTCTCCACTACCCCACCCTCATGACCCCGGCGCTCTGTGCCCGGATTG
CCGTTGGCTGTTGGTTGGGAGGCCTGGCTGGGCCGGTGGCTGAAATTTCTCTGGTGTCCCGTCT
CCCTTTCTGTGGCCCCAATCACATTCAGCACATCTTTTGTGATTTCCCTCCTGTGCTGAGCTTG
GCCTGTACAGACACATCTGTCAATGTCCTAGTGGACTTCGTTATCAACTCCTGCAAAATCCTGG
CCACCTTCCTGTTGATCCTCAGCTCCTATGTCCAGATCATCCGCACGGTACTCAGGATTCCTTC
AGTTGCAGGCAAGACAAAGGCCTTCTCCACCTGTGCCTCCCACCTGACCGTGGTTCTCATCTTC
TACGGGAGCATCCTCTTCATGTATGTGCGGCTGAAGAAGAGCTACTCGCTGGACTATGACCGCG
CACTGGCTGTGATCTACTCGGTGCTCACGCCTTTTCTCAACCCCTTCATCTACAGCTTGCGCAA
CAAGGATATTAAGGAGGCTGTGAGGAGGCAGTTGAGGAGGTCAGGGATACTGTGA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001300797	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AEN80222	(Get FASTA)	NCBI Sequence Viewer
	CAD24249	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000017164.5
	ENSCAFP00040030209.1
	ENSCAFP00845022380
	ENSCAFP00845022380.1

RefSeq Acc Id:

NP_001300797 ⟸ NM_001313868

- UniProtKB:

G3FJC6 (UniProtKB/TrEMBL), F1PCK5 (UniProtKB/TrEMBL), A0A8C0T2U9 (UniProtKB/TrEMBL), A0A8P0SGP2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSGEPWTPGNWSWVTEFIILGFPHVQGVQAYLFVLLLLIYVTTVLGNLLIFLVVRLDPRLHTPM
YHFVSALSLLELGYTAATIPKMLSNLLSEEKTISFSGCLLQIYFFHSLGAAECYLLTAMAYDRY
LAICQPLHYPTLMTPALCARIAVGCWLGGLAGPVAEISLVSRLPFCGPNHIQHIFCDFPPVLSL
ACTDTSVNVLVDFVINSCKILATFLLILSSYVQIIRTVLRIPSVAGKTKAFSTCASHLTVVLIF
YGSILFMYVRLKKSYSLDYDRALAVIYSVLTPFLNPFIYSLRNKDIKEAVRRQLRRSGIL

hide sequence

RefSeq Acc Id:

ENSCAFP00000017164 ⟸ ENSCAFT00000018531

RefSeq Acc Id:

ENSCAFP00845022380 ⟸ ENSCAFT00845028452

Protein Domains

G-protein coupled receptors family 1 profile

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000011684	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00040018765	UniProtKB/TrEMBL
	ENSCAFG00845015998	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000018531.5	UniProtKB/TrEMBL
	ENSCAFT00040034697.1	UniProtKB/TrEMBL
	ENSCAFT00845028452	ENTREZGENE
	ENSCAFT00845028452.1	UniProtKB/TrEMBL
Gene3D-CATH	Rhodopsin 7-helix transmembrane proteins	UniProtKB/TrEMBL
InterPro	GPCR_Rhodpsn	UniProtKB/TrEMBL
	GPCR_Rhodpsn_7TM	UniProtKB/TrEMBL
	Olfact_rcpt	UniProtKB/TrEMBL
KEGG Report	cfa:488618	UniProtKB/TrEMBL
NCBI Gene	OR6N1	ENTREZGENE
PANTHER	G-PROTEIN COUPLED RECEPTOR	UniProtKB/TrEMBL
	OLFACTORY RECEPTOR	UniProtKB/TrEMBL
Pfam	7tm_4	UniProtKB/TrEMBL
PRINTS	GPCRRHODOPSN	UniProtKB/TrEMBL
	OLFACTORYR	UniProtKB/TrEMBL
PROSITE	G_PROTEIN_RECEP_F1_1	UniProtKB/TrEMBL
	G_PROTEIN_RECEP_F1_2	UniProtKB/TrEMBL
Superfamily-SCOP	Family A G protein-coupled receptor-like	UniProtKB/TrEMBL
UniProt	A0A8C0T2U9	ENTREZGENE, UniProtKB/TrEMBL
	A0A8P0SGP2	ENTREZGENE
	F1PCK5	ENTREZGENE, UniProtKB/TrEMBL
	G3FJC6	ENTREZGENE
UniProt Secondary	A0A8P0SGP2	UniProtKB/TrEMBL
	G3FJC6	UniProtKB/TrEMBL
VGNC ID	VGNC:97131	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2020-02-18	OR6N1	olfactory receptor family 6 subfamily N member 1	OR6N1	olfactory receptor, family 6, subfamily N, member 1	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Send us a Message

Imported Disease Annotations - ClinVar