STK4 (serine/threonine kinase 4) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: STK4 (serine/threonine kinase 4) Canis lupus familiaris
Analyze
Symbol: STK4
Name: serine/threonine kinase 4
RGD ID: 12249117
Description: ENCODES a protein that exhibits identical protein binding (ortholog); magnesium ion binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN apoptotic process (ortholog); branching involved in blood vessel morphogenesis (ortholog); cell differentiation involved in embryonic placenta development (ortholog); ASSOCIATED WITH bipolar disorder (ortholog); primary immunodeficiency disease (ortholog); T-Cell Immunodeficiency, Recurrent Infections, and Autoimmunity with or without Cardiac Malformations (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nuclear body (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOW QUALITY PROTEIN: serine/threonine-protein kinase 4; serine/threonine-protein kinase 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12432,375,630 - 32,463,848 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2432,375,189 - 32,521,042 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2432,021,037 - 32,109,251 (+)NCBI
ROS_Cfam_1.02433,086,419 - 33,174,685 (+)NCBI
UMICH_Zoey_3.12432,347,829 - 32,432,566 (+)NCBI
UNSW_CanFamBas_1.02432,462,830 - 32,551,067 (+)NCBI
UU_Cfam_GSD_1.02433,004,538 - 33,092,881 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

Genomics

Comparative Map Data
STK4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12432,375,630 - 32,463,848 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2432,375,189 - 32,521,042 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2432,021,037 - 32,109,251 (+)NCBI
ROS_Cfam_1.02433,086,419 - 33,174,685 (+)NCBI
UMICH_Zoey_3.12432,347,829 - 32,432,566 (+)NCBI
UNSW_CanFamBas_1.02432,462,830 - 32,551,067 (+)NCBI
UU_Cfam_GSD_1.02433,004,538 - 33,092,881 (+)NCBI
STK4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2044,966,479 - 45,080,021 (+)EnsemblGRCh38hg38GRCh38
GRCh382044,966,470 - 45,080,021 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372043,595,153 - 43,708,662 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362043,028,534 - 43,142,008 (+)NCBINCBI36hg18NCBI36
Build 342043,028,533 - 43,142,005NCBI
Celera2040,303,755 - 40,417,237 (+)NCBI
Cytogenetic Map20q13.12NCBI
HuRef2040,336,825 - 40,450,492 (+)NCBIHuRef
CHM1_12043,497,900 - 43,611,341 (+)NCBICHM1_1
Stk4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392163,916,033 - 163,997,444 (+)NCBIGRCm39mm39
GRCm39 Ensembl2163,912,242 - 163,997,444 (+)Ensembl
GRCm382164,074,113 - 164,155,524 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2164,070,322 - 164,155,524 (+)EnsemblGRCm38mm10GRCm38
MGSCv372163,899,914 - 163,981,257 (+)NCBIGRCm37mm9NCBIm37
MGSCv362163,765,619 - 163,846,962 (+)NCBImm8
Celera2170,004,346 - 170,087,071 (+)NCBICelera
Cytogenetic Map2H3NCBI
Stk4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.23152,745,958 - 152,827,747 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl3152,745,681 - 152,827,744 (+)Ensembl
Rnor_6.03160,467,552 - 160,546,540 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3160,467,552 - 160,546,540 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03166,652,145 - 166,731,213 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43155,014,941 - 155,095,272 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13154,920,949 - 154,998,005 (+)NCBI
Celera3151,397,134 - 151,475,844 (+)NCBICelera
Cytogenetic Map3q42NCBI
Stk4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544512,308,285 - 12,399,012 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544512,308,285 - 12,399,012 (-)NCBIChiLan1.0ChiLan1.0
STK4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12042,389,611 - 42,503,014 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2042,389,615 - 42,503,014 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02041,297,157 - 41,410,487 (+)NCBIMhudiblu_PPA_v0panPan3
Stk4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640192,233,117 - 192,331,335 (-)NCBI
SpeTri2.0NW_0049365147,686,760 - 7,784,948 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
STK4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1747,376,115 - 47,475,718 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11747,387,594 - 47,475,705 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21752,912,419 - 52,932,976 (+)NCBISscrofa10.2Sscrofa10.2susScr3
STK4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1218,737,484 - 18,844,610 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl218,742,162 - 18,844,647 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605067,388,889 - 67,493,337 (-)NCBIVero_WHO_p1.0
Stk4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247909,415,172 - 9,521,103 (-)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 2 11 6 5 12 8
Low 3 5 11 6 6 1 6 8 2 6
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_022408851 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022408852 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038433935 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038433936 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038433937 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038433938 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038433939 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038457699 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038457700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038509083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038509084 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038509085 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038509086 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038509087 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038572429 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038636691 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038636692 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038636693 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038636694 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038636695 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_534432 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000024 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000266 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000063 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000376 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000024 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000015285   ⟹   ENSCAFP00000014145
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2432,375,189 - 32,461,620 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000062007   ⟹   ENSCAFP00000050655
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2432,385,413 - 32,461,620 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000072198   ⟹   ENSCAFP00000043438
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2432,375,189 - 32,521,042 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000081696   ⟹   ENSCAFP00000044320
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2432,375,189 - 32,461,620 (+)Ensembl
RefSeq Acc Id: XM_022408851   ⟹   XP_022264559
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12432,381,064 - 32,460,029 (+)NCBI
Dog10K_Boxer_Tasha2432,021,126 - 32,105,427 (+)NCBI
Sequence:
RefSeq Acc Id: XM_022408852   ⟹   XP_022264560
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12432,385,665 - 32,460,029 (+)NCBI
Dog10K_Boxer_Tasha2432,026,482 - 32,105,427 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038433935   ⟹   XP_038289863
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02433,086,419 - 33,174,685 (+)NCBI
RefSeq Acc Id: XM_038433936   ⟹   XP_038289864
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02433,086,508 - 33,170,861 (+)NCBI
RefSeq Acc Id: XM_038433937   ⟹   XP_038289865
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02433,086,508 - 33,170,861 (+)NCBI
RefSeq Acc Id: XM_038433938   ⟹   XP_038289866
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02433,086,537 - 33,170,861 (+)NCBI
RefSeq Acc Id: XM_038433939   ⟹   XP_038289867
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02433,091,870 - 33,170,861 (+)NCBI
RefSeq Acc Id: XM_038457699   ⟹   XP_038313627
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha2432,021,126 - 32,105,427 (+)NCBI
RefSeq Acc Id: XM_038457700   ⟹   XP_038313628
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha2432,021,155 - 32,105,427 (+)NCBI
RefSeq Acc Id: XM_038509083   ⟹   XP_038365011
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12432,347,829 - 32,432,566 (+)NCBI
RefSeq Acc Id: XM_038509084   ⟹   XP_038365012
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12432,347,918 - 32,432,137 (+)NCBI
RefSeq Acc Id: XM_038509085   ⟹   XP_038365013
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12432,347,918 - 32,432,137 (+)NCBI
RefSeq Acc Id: XM_038509086   ⟹   XP_038365014
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12432,347,947 - 32,432,137 (+)NCBI
RefSeq Acc Id: XM_038509087   ⟹   XP_038365015
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12432,353,269 - 32,432,137 (+)NCBI
RefSeq Acc Id: XM_038572429   ⟹   XP_038428357
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02433,004,538 - 33,092,881 (+)NCBI
RefSeq Acc Id: XM_038636691   ⟹   XP_038492619
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02432,462,830 - 32,551,067 (+)NCBI
RefSeq Acc Id: XM_038636692   ⟹   XP_038492620
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02432,462,919 - 32,547,243 (+)NCBI
RefSeq Acc Id: XM_038636693   ⟹   XP_038492621
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02432,462,919 - 32,547,243 (+)NCBI
RefSeq Acc Id: XM_038636694   ⟹   XP_038492622
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02432,462,948 - 32,547,243 (+)NCBI
RefSeq Acc Id: XM_038636695   ⟹   XP_038492623
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02432,468,264 - 32,547,243 (+)NCBI
RefSeq Acc Id: XM_534432   ⟹   XP_534432
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12432,375,630 - 32,463,848 (+)NCBI
Dog10K_Boxer_Tasha2432,021,037 - 32,109,251 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_534432   ⟸   XM_534432
- Peptide Label: isoform X1
- UniProtKB: F1PGB1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022264559   ⟸   XM_022408851
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_022264560   ⟸   XM_022408852
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSCAFP00000014145   ⟸   ENSCAFT00000015285
RefSeq Acc Id: ENSCAFP00000050655   ⟸   ENSCAFT00000062007
RefSeq Acc Id: ENSCAFP00000043438   ⟸   ENSCAFT00000072198
RefSeq Acc Id: ENSCAFP00000044320   ⟸   ENSCAFT00000081696
RefSeq Acc Id: XP_038365011   ⟸   XM_038509083
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038365013   ⟸   XM_038509085
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038365012   ⟸   XM_038509084
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038365014   ⟸   XM_038509086
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038365015   ⟸   XM_038509087
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038492619   ⟸   XM_038636691
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038492621   ⟸   XM_038636693
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038492620   ⟸   XM_038636692
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038492622   ⟸   XM_038636694
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038492623   ⟸   XM_038636695
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038289863   ⟸   XM_038433935
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038289865   ⟸   XM_038433937
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038289864   ⟸   XM_038433936
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038289866   ⟸   XM_038433938
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038289867   ⟸   XM_038433939
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038313627   ⟸   XM_038457699
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038313628   ⟸   XM_038457700
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038428357   ⟸   XM_038572429
- Peptide Label: isoform X3

Promoters
RGD ID:13687626
Promoter ID:EPDNEW_C5694
Type:initiation region
Name:STK4_1
Description:serine/threonine kinase 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12432,375,716 - 32,375,776EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000009615 Ensembl
NCBI Gene STK4 ENTREZGENE
UniProt F1PGB1 ENTREZGENE
VGNC ID VGNC:46922 ENTREZGENE