WNT9B (Wnt family member 9B) - Rat Genome Database

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Gene: WNT9B (Wnt family member 9B) Canis lupus familiaris
Analyze
Symbol: WNT9B
Name: Wnt family member 9B
RGD ID: 12246791
Description: ENCODES a protein that exhibits co-receptor binding (inferred); cytokine activity (inferred); frizzled binding (inferred); INVOLVED IN branching involved in ureteric bud morphogenesis (ortholog); branching morphogenesis of an epithelial tube (ortholog); canonical Wnt signaling pathway (ortholog); PARTICIPATES IN Wnt signaling pathway; Wnt signaling pathway; Wnt signaling, canonical pathway; ASSOCIATED WITH chronic kidney disease (ortholog); genetic disease (ortholog); progressive myoclonus epilepsy (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: protein Wnt-9b
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1910,157,607 - 10,172,664 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl910,149,842 - 10,172,654 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha910,125,720 - 10,132,894 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0911,755,792 - 11,762,969 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl911,740,175 - 11,762,959 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1910,766,706 - 10,773,876 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0916,748,106 - 16,755,280 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0916,695,500 - 16,702,675 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
WNT9B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1910,157,607 - 10,172,664 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl910,149,842 - 10,172,654 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha910,125,720 - 10,132,894 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0911,755,792 - 11,762,969 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl911,740,175 - 11,762,959 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1910,766,706 - 10,773,876 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0916,748,106 - 16,755,280 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0916,695,500 - 16,702,675 (-)NCBIUU_Cfam_GSD_1.0
WNT9B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381746,833,189 - 46,886,738 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1746,833,201 - 46,886,730 (+)EnsemblGRCh38hg38GRCh38
GRCh371744,928,949 - 44,964,104 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361742,283,967 - 42,309,436 (+)NCBINCBI36Build 36hg18NCBI36
Build 341742,283,966 - 42,309,436NCBI
Celera1741,378,455 - 41,403,922 (+)NCBICelera
Cytogenetic Map17q21.32NCBI
HuRef1740,307,364 - 40,332,821 (+)NCBIHuRef
CHM1_11744,993,095 - 45,018,563 (+)NCBICHM1_1
T2T-CHM13v2.01747,694,652 - 47,748,202 (+)NCBIT2T-CHM13v2.0
Wnt9b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911103,618,188 - 103,666,098 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11103,618,190 - 103,640,647 (-)EnsemblGRCm39 Ensembl
GRCm3811103,727,362 - 103,775,272 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11103,727,364 - 103,749,821 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711103,588,677 - 103,611,135 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611103,543,453 - 103,565,911 (-)NCBIMGSCv36mm8
Celera11115,442,222 - 115,464,694 (-)NCBICelera
Cytogenetic Map11E1NCBI
cM Map1167.47NCBI
Wnt9b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81089,135,362 - 89,157,065 (-)NCBIGRCr8
mRatBN7.21088,635,330 - 88,657,035 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1088,635,331 - 88,657,035 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1093,673,741 - 93,695,456 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01093,138,896 - 93,160,602 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01088,532,248 - 88,553,957 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01091,785,892 - 91,808,061 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1091,785,893 - 91,807,937 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01091,552,384 - 91,574,275 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41092,880,020 - 92,901,641 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11092,897,918 - 92,916,111 (-)NCBI
Celera1087,334,808 - 87,356,461 (-)NCBICelera
Cytogenetic Map10q32.1NCBI
Wnt9b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547810,816,405 - 10,841,416 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495547810,816,405 - 10,841,416 (+)NCBIChiLan1.0ChiLan1.0
WNT9B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21918,130,185 - 18,165,182 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11720,096,138 - 20,131,144 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01710,616,957 - 10,651,954 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11710,801,176 - 10,818,516 (-)NCBIpanpan1.1PanPan1.1panPan2
Wnt9b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560217,290,995 - 17,299,116 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365411,899,039 - 1,939,561 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365411,899,039 - 1,939,561 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WNT9B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1217,709,046 - 17,733,431 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11217,709,046 - 17,733,434 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21217,733,977 - 17,737,390 (-)NCBISscrofa10.2Sscrofa10.2susScr3
WNT9B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11660,560,132 - 60,596,782 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1660,581,258 - 60,586,596 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607731,283,829 - 31,320,517 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Wnt9b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248492,957,153 - 2,976,179 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248492,971,658 - 2,979,864 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in WNT9B
103 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium
Low 1 3 1 6 1 1 4 3
Below cutoff 5 4 19 5 5 5 6 12 7 6 3

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000021316   ⟹   ENSCAFP00000019792
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl910,149,842 - 10,172,654 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000043450   ⟹   ENSCAFP00000039322
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl910,165,571 - 10,172,654 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845042357   ⟹   ENSCAFP00845033206
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl911,740,175 - 11,762,959 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845042400   ⟹   ENSCAFP00845033242
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl911,755,873 - 11,762,959 (+)Ensembl
RefSeq Acc Id: XM_014116366   ⟹   XP_013971841
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1910,157,607 - 10,172,664 (+)NCBI
Dog10K_Boxer_Tasha910,125,720 - 10,132,894 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038487586   ⟹   XP_038343514
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1910,766,706 - 10,773,876 (+)NCBI
RefSeq Acc Id: XM_038546094   ⟹   XP_038402022
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0916,695,500 - 16,702,675 (-)NCBI
RefSeq Acc Id: XM_038610118   ⟹   XP_038466046
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0916,748,106 - 16,755,280 (-)NCBI
RefSeq Acc Id: XM_038675181   ⟹   XP_038531109
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0911,755,792 - 11,762,969 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_013971841   ⟸   XM_014116366
- UniProtKB: A0A8C0LSU2 (UniProtKB/TrEMBL),   A0A8I3PG82 (UniProtKB/TrEMBL),   A0A8P0STL3 (UniProtKB/TrEMBL),   A0A8C0LU08 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000019792   ⟸   ENSCAFT00000021316
RefSeq Acc Id: ENSCAFP00000039322   ⟸   ENSCAFT00000043450
RefSeq Acc Id: XP_038343514   ⟸   XM_038487586
RefSeq Acc Id: XP_038466046   ⟸   XM_038610118
RefSeq Acc Id: XP_038531109   ⟸   XM_038675181
- UniProtKB: A0A8C0LSU2 (UniProtKB/TrEMBL),   A0A8I3PG82 (UniProtKB/TrEMBL),   A0A8P0STL3 (UniProtKB/TrEMBL),   A0A8C0LU08 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038402022   ⟸   XM_038546094
- UniProtKB: A0A8C0LSU2 (UniProtKB/TrEMBL),   A0A8C0LU08 (UniProtKB/TrEMBL),   A0A8I3PG82 (UniProtKB/TrEMBL),   A0A8P0STL3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845033206   ⟸   ENSCAFT00845042357
RefSeq Acc Id: ENSCAFP00845033242   ⟸   ENSCAFT00845042400

Promoters
RGD ID:13684450
Promoter ID:EPDNEW_C2518
Type:multiple initiation site
Name:WNT9B_1
Description:Wnt family member 9B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1910,149,866 - 10,149,926EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000013433 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030009117 UniProtKB/TrEMBL
  ENSCAFG00040011970 UniProtKB/TrEMBL
  ENSCAFG00845023985 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000021316.7 UniProtKB/TrEMBL
  ENSCAFT00000043450.3 UniProtKB/TrEMBL
  ENSCAFT00030016900.1 UniProtKB/TrEMBL
  ENSCAFT00040022118.1 UniProtKB/TrEMBL
  ENSCAFT00845042357.1 UniProtKB/TrEMBL
  ENSCAFT00845042400 ENTREZGENE
  ENSCAFT00845042400.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.2460.20 UniProtKB/TrEMBL
InterPro Wnt UniProtKB/TrEMBL
  Wnt_C UniProtKB/TrEMBL
  Wnt_CS UniProtKB/TrEMBL
KEGG Report cfa:490919 UniProtKB/TrEMBL
NCBI Gene WNT9B ENTREZGENE
PANTHER PTHR12027 UniProtKB/TrEMBL
  PTHR12027:SF84 UniProtKB/TrEMBL
Pfam wnt UniProtKB/TrEMBL
PRINTS WNTPROTEIN UniProtKB/TrEMBL
PROSITE WNT1 UniProtKB/TrEMBL
SMART WNT1 UniProtKB/TrEMBL
UniProt A0A8C0LSU2 ENTREZGENE
  A0A8C0LU08 ENTREZGENE
  A0A8C0SCS4_CANLF UniProtKB/TrEMBL
  A0A8I3PG49_CANLF UniProtKB/TrEMBL
  A0A8I3PG82 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0STL3 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:48431 ENTREZGENE