MT-ATP8 (mitochondrially encoded ATP synthase membrane subunit 8) - Rat Genome Database

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Gene: MT-ATP8 (mitochondrially encoded ATP synthase membrane subunit 8) Canis lupus familiaris
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Symbol: MT-ATP8
Name: mitochondrially encoded ATP synthase membrane subunit 8
RGD ID: 12244767
Description: ENCODES a protein that exhibits proton-transporting ATP synthase activity, rotational mechanism (ortholog); INVOLVED IN proton motive force-driven mitochondrial ATP synthesis (ortholog); response to hyperoxia (ortholog); ASSOCIATED WITH Acute Liver Failure (ortholog); Apical Hypertrophic Cardiomyopathy and Neuropathy (ortholog); bicuspid aortic valve disease (ortholog); FOUND IN mitochondrial proton-transporting ATP synthase complex (ortholog)
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: ATP synthase F0 subunit 8; ATP8
RGD Orthologs
Human
Mouse
Rat
Pig
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1MT7,803 - 8,006 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblMT7,803 - 8,006 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaMT7,803 - 8,006 (+)NCBIDog10K_Boxer_Tasha


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

Genomics

Comparative Map Data
MT-ATP8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1MT7,803 - 8,006 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblMT7,803 - 8,006 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaMT7,803 - 8,006 (+)NCBIDog10K_Boxer_Tasha
MT-ATP8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38MT8,366 - 8,572 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblMT8,366 - 8,572 (+)EnsemblGRCh38hg38GRCh38
GRCh37MT8,366 - 8,572 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36MT8,367 - 8,573 (+)NCBINCBI36Build 36hg18NCBI36
mt-Atp8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39MT7,766 - 7,969 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblMT7,766 - 7,969 (+)EnsemblGRCm39 Ensembl
GRCm38MT7,766 - 7,969 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblMT7,766 - 7,969 (+)EnsemblGRCm38mm10GRCm38
MGSCv37MT7,766 - 7,969 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Mt-atp8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2MT7,758 - 7,961 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2MT7,758 - 7,961 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2MT7,758 - 7,961 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblMT7,758 - 7,961 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0MT7,758 - 7,961 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblMT7,758 - 7,961 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0MT7,758 - 7,961 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4MT7,758 - 7,961 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Cytogenetic MapMT NCBI
MT-ATP8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblMT8,959 - 9,162 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1MT8,959 - 9,162 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2MT8,959 - 9,162 (+)NCBISscrofa10.2Sscrofa10.2susScr3

Variants

.
Variants in MT-ATP8
17 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High 5 4 19 5 5 5 4 1 9 3 8 4
Medium 1 1 1 1 1 3 1 1
Low
Below cutoff

Sequence

Nucleotide Sequences
GenBank Nucleotide U96639 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000034835   ⟹   ENSCAFP00000030313
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 EnsemblMT7,803 - 8,006 (+)Ensembl
Protein Sequences
Protein RefSeqs NP_008475 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAD04767 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: ENSCAFP00000030313   ⟸   ENSCAFT00000034835


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000022728 Ensembl
InterPro ATP8_mammal UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATP8_metazoa UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report cfa:804487 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene ATP8 ENTREZGENE
PANTHER ATP SYNTHASE PROTEIN 8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR13722 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam ATP-synt_8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A060GW64 ENTREZGENE, UniProtKB/TrEMBL
  A0A0K0K3E0 ENTREZGENE
  A0A172R7Q5 ENTREZGENE, UniProtKB/TrEMBL
  A0A172R8A3 ENTREZGENE, UniProtKB/TrEMBL
  A0A172RAV4 ENTREZGENE, UniProtKB/TrEMBL
  A0A172RN71 ENTREZGENE, UniProtKB/TrEMBL
  A0A1C9IBQ4 ENTREZGENE
  A0A1C9ICJ8 ENTREZGENE
  A0A5C0CJE1 ENTREZGENE
  A0A679G475 ENTREZGENE
  A0A6B9M1Z7 ENTREZGENE
  A6Q067 ENTREZGENE
  ATP8_CANLF UniProtKB/Swiss-Prot
  B9TYB1 ENTREZGENE, UniProtKB/TrEMBL
  C4MS78 ENTREZGENE, UniProtKB/TrEMBL
  C4MWZ2 ENTREZGENE
  C4MX05 ENTREZGENE
  C7FGR2 ENTREZGENE
  D4QA90 ENTREZGENE
  H8Y5X6 ENTREZGENE
  M1Q372 ENTREZGENE
  Q1HK99 ENTREZGENE
  Q1HKB2 ENTREZGENE
  Q1HKK3 ENTREZGENE, UniProtKB/TrEMBL
  Q3L6Z3 ENTREZGENE
  Q49RP4 ENTREZGENE, UniProtKB/TrEMBL
  Q49RZ8 ENTREZGENE, UniProtKB/TrEMBL
  Q9ZZ63 ENTREZGENE
  R9TDV2 ENTREZGENE
  V5LI60 ENTREZGENE
  V5LIL7 ENTREZGENE
  V5LJR6 ENTREZGENE
  V5LJW3 ENTREZGENE
  V5LK34 ENTREZGENE
  V5LKS8 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-05-04 MT-ATP8  mitochondrially encoded ATP synthase membrane subunit 8  ATP8  ATP synthase F0 subunit 8  Symbol and/or name change 19259463 PROVISIONAL