NUBP1 (NUBP iron-sulfur cluster assembly factor 1, cytosolic) - Rat Genome Database

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Gene: NUBP1 (NUBP iron-sulfur cluster assembly factor 1, cytosolic) Canis lupus familiaris
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Symbol: NUBP1
Name: NUBP iron-sulfur cluster assembly factor 1, cytosolic
RGD ID: 12244391
Description: ENCODES a protein that exhibits 4 iron, 4 sulfur cluster binding (inferred); ATP binding (inferred); ATP-dependent FeS chaperone activity (inferred); INVOLVED IN centrosome localization (ortholog); negative regulation of centrosome duplication (ortholog); protein localization to cell cortex (ortholog); PARTICIPATES IN cytosolic iron-sulfur cluster protein assembly pathway; ASSOCIATED WITH Charcot-Marie-Tooth disease type 1C (ortholog); Landau-Kleffner syndrome (ortholog); MHC class II deficiency (ortholog); FOUND IN centrosome (inferred); cytoplasm (inferred); cytosol (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cytosolic Fe-S cluster assembly factor NUBP1; nucleotide binding protein 1; nucleotide binding protein 1 (MinD homolog, E. coli)
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1631,900,540 - 31,922,087 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl631,896,596 - 31,921,989 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha633,282,660 - 33,304,486 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0632,082,705 - 32,104,573 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl632,081,940 - 32,104,479 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1631,896,734 - 31,918,569 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0631,770,561 - 31,792,362 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0632,194,799 - 32,216,643 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
centrosome  (IEA)
cytoplasm  (IEA)
cytosol  (IBA,IEA)
Golgi apparatus  (IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
NUBP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1631,900,540 - 31,922,087 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl631,896,596 - 31,921,989 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha633,282,660 - 33,304,486 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0632,082,705 - 32,104,573 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl632,081,940 - 32,104,479 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1631,896,734 - 31,918,569 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0631,770,561 - 31,792,362 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0632,194,799 - 32,216,643 (-)NCBIUU_Cfam_GSD_1.0
NUBP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381610,743,842 - 10,769,351 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1610,743,786 - 10,769,351 (+)EnsemblGRCh38hg38GRCh38
GRCh371610,837,699 - 10,863,208 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361610,745,199 - 10,770,709 (+)NCBINCBI36Build 36hg18NCBI36
Build 341610,745,217 - 10,770,709NCBI
Celera1611,007,059 - 11,032,475 (+)NCBICelera
Cytogenetic Map16p13.13NCBI
HuRef1610,756,412 - 10,781,588 (+)NCBIHuRef
CHM1_11610,837,712 - 10,863,204 (+)NCBICHM1_1
T2T-CHM13v2.01610,779,762 - 10,805,269 (+)NCBIT2T-CHM13v2.0
Nubp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391610,229,802 - 10,242,317 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1610,229,812 - 10,242,292 (+)EnsemblGRCm39 Ensembl
GRCm381610,411,884 - 10,424,453 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1610,411,948 - 10,424,428 (+)EnsemblGRCm38mm10GRCm38
MGSCv371610,412,031 - 10,424,521 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361610,325,553 - 10,337,109 (+)NCBIMGSCv36mm8
Celera1611,045,448 - 11,057,938 (+)NCBICelera
Cytogenetic Map16A1NCBI
cM Map165.61NCBI
Nubp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8105,766,157 - 5,777,648 (-)NCBIGRCr8
mRatBN7.2105,259,328 - 5,270,848 (-)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_Utx109,955,670 - 9,967,161 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0109,476,783 - 9,488,274 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0105,115,152 - 5,126,642 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0105,333,378 - 5,343,949 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl105,333,378 - 5,344,121 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0104,155,446 - 4,166,017 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4105,206,634 - 5,217,205 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1105,206,633 - 5,217,205 (-)NCBI
Celera104,276,872 - 4,287,443 (-)NCBICelera
Cytogenetic Map10q11NCBI
Nubp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554427,717,422 - 7,732,496 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554427,717,422 - 7,732,496 (-)NCBIChiLan1.0ChiLan1.0
NUBP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21811,236,566 - 11,315,874 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11615,012,495 - 15,091,492 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0169,681,800 - 9,708,673 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11610,906,347 - 10,931,799 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1610,906,719 - 10,931,800 (+)Ensemblpanpan1.1panPan2
Nubp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344111,126,784 - 111,140,480 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365308,971,380 - 8,986,033 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365308,970,963 - 8,985,925 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NUBP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl332,311,779 - 32,340,034 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1332,311,774 - 32,340,120 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2333,045,133 - 33,072,061 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NUBP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1510,224,965 - 10,248,328 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl510,225,173 - 10,249,047 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606819,923,874 - 19,947,229 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nubp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248248,024,575 - 8,040,364 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248248,024,459 - 8,040,353 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in NUBP1
256 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000030094   ⟹   ENSCAFP00000027969
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl631,896,596 - 31,921,989 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000079511   ⟹   ENSCAFP00000045342
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl631,901,464 - 31,921,989 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000080194   ⟹   ENSCAFP00000048926
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl631,901,584 - 31,921,989 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000088982   ⟹   ENSCAFP00000065626
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl631,901,464 - 31,921,989 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845023809   ⟹   ENSCAFP00845018691
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl632,081,940 - 32,104,479 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845023828   ⟹   ENSCAFP00845018707
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl632,081,940 - 32,104,479 (-)Ensembl
RefSeq Acc Id: XM_038479167   ⟹   XP_038335095
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1631,896,734 - 31,918,569 (-)NCBI
RefSeq Acc Id: XM_038540394   ⟹   XP_038396322
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0632,194,799 - 32,216,643 (-)NCBI
RefSeq Acc Id: XM_038604495   ⟹   XP_038460423
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0631,770,561 - 31,792,362 (-)NCBI
RefSeq Acc Id: XM_038669182   ⟹   XP_038525110
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0632,082,705 - 32,104,573 (-)NCBI
RefSeq Acc Id: XM_536975   ⟹   XP_536975
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1631,900,540 - 31,922,087 (-)NCBI
Dog10K_Boxer_Tasha633,282,660 - 33,304,486 (-)NCBI
Sequence:
RefSeq Acc Id: XP_536975   ⟸   XM_536975
- UniProtKB: A0A8C0QFE4 (UniProtKB/TrEMBL),   A0A8I3NFS3 (UniProtKB/TrEMBL),   A0A8C0QBB4 (UniProtKB/TrEMBL),   A0A8I3S020 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000065626   ⟸   ENSCAFT00000088982
Ensembl Acc Id: ENSCAFP00000048926   ⟸   ENSCAFT00000080194
Ensembl Acc Id: ENSCAFP00000027969   ⟸   ENSCAFT00000030094
Ensembl Acc Id: ENSCAFP00000045342   ⟸   ENSCAFT00000079511
RefSeq Acc Id: XP_038335095   ⟸   XM_038479167
RefSeq Acc Id: XP_038460423   ⟸   XM_038604495
RefSeq Acc Id: XP_038525110   ⟸   XM_038669182
- UniProtKB: A0A8C0QFE4 (UniProtKB/TrEMBL),   A0A8I3NFS3 (UniProtKB/TrEMBL),   A0A8C0QBB4 (UniProtKB/TrEMBL),   A0A8I3S020 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038396322   ⟸   XM_038540394
- UniProtKB: A0A8C0QBB4 (UniProtKB/TrEMBL),   A0A8C0QFE4 (UniProtKB/TrEMBL),   A0A8I3NFS3 (UniProtKB/TrEMBL),   A0A8I3S020 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845018707   ⟸   ENSCAFT00845023828
Ensembl Acc Id: ENSCAFP00845018691   ⟸   ENSCAFT00845023809

Promoters
RGD ID:13683697
Promoter ID:EPDNEW_C1765
Type:multiple initiation site
Name:NUBP1_1
Description:nucleotide binding protein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1631,922,001 - 31,922,061EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000018947 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030009744 UniProtKB/TrEMBL
  ENSCAFG00040004878 UniProtKB/TrEMBL
  ENSCAFG00845013369 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000030094.5 UniProtKB/TrEMBL
  ENSCAFT00000079511.2 UniProtKB/TrEMBL
  ENSCAFT00030018031.1 UniProtKB/TrEMBL
  ENSCAFT00030018129.1 UniProtKB/TrEMBL
  ENSCAFT00040009185.1 UniProtKB/TrEMBL
  ENSCAFT00040009235.1 UniProtKB/TrEMBL
  ENSCAFT00845023809 ENTREZGENE
  ENSCAFT00845023809.1 UniProtKB/TrEMBL
  ENSCAFT00845023828.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro Mrp/NBP35_ATP-bd UniProtKB/TrEMBL
  Mrp_CS UniProtKB/TrEMBL
  NUBP1/Nbp35 UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  YlxH/NBP35 UniProtKB/TrEMBL
KEGG Report cfa:479850 UniProtKB/TrEMBL
NCBI Gene NUBP1 ENTREZGENE
PANTHER CYTOSOLIC FE-S CLUSTER ASSEMBLY FACTOR NUBP1 UniProtKB/TrEMBL
  PTHR23264 UniProtKB/TrEMBL
Pfam ParA UniProtKB/TrEMBL
PROSITE MRP UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A8C0QBB4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0QFE4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NFS3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3S020 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:44017 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-12-20 NUBP1  NUBP iron-sulfur cluster assembly factor 1, cytosolic  NUBP1  nucleotide binding protein 1  Symbol and/or name change 19259463 PROVISIONAL