CD177 (CD177 molecule) - Rat Genome Database

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Gene: CD177 (CD177 molecule) Canis lupus familiaris
Analyze
Symbol: CD177
Name: CD177 molecule
RGD ID: 12239308
Description: ENCODES a protein that exhibits calcium-dependent protein binding (ortholog); integrin binding (ortholog); protease binding (ortholog); INVOLVED IN cell adhesion (ortholog); neutrophil extravasation (ortholog); neutrophil migration (ortholog); ASSOCIATED WITH genetic disease (ortholog); schizophrenia (ortholog); FOUND IN plasma membrane (ortholog); secretory granule membrane (ortholog); tertiary granule membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: CD177 antigen; CD177 antigen-like
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11111,693,234 - 111,698,879 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1111,693,005 - 111,698,742 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1111,172,751 - 111,178,674 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01112,303,259 - 112,309,197 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11111,891,326 - 111,897,264 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01111,525,114 - 111,531,052 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01112,409,530 - 112,415,468 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
CD177
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11111,693,234 - 111,698,879 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1111,693,005 - 111,698,742 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1111,172,751 - 111,178,674 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01112,303,259 - 112,309,197 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11111,891,326 - 111,897,264 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01111,525,114 - 111,531,052 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01112,409,530 - 112,415,468 (+)NCBIUU_Cfam_GSD_1.0
CD177
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381943,353,686 - 43,366,081 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1943,353,686 - 43,363,172 (+)EnsemblGRCh38hg38GRCh38
GRCh371943,857,838 - 43,867,324 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361948,549,665 - 48,559,320 (+)NCBINCBI36Build 36hg18NCBI36
Celera1940,658,322 - 40,667,941 (+)NCBICelera
Cytogenetic Map19q13.31NCBI
HuRef1940,287,517 - 40,297,162 (+)NCBIHuRef
CHM1_11943,859,366 - 43,869,014 (+)NCBICHM1_1
T2T-CHM13v2.01946,174,138 - 46,186,504 (+)NCBIT2T-CHM13v2.0
Cd177
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39724,443,408 - 24,459,759 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl724,443,408 - 24,459,736 (-)EnsemblGRCm39 Ensembl
GRCm38724,743,983 - 24,760,334 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl724,743,983 - 24,760,311 (-)EnsemblGRCm38mm10GRCm38
MGSCv37725,529,002 - 25,545,330 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36724,452,743 - 24,469,071 (-)NCBIMGSCv36mm8
Celera719,358,481 - 19,374,808 (-)NCBICelera
Cytogenetic Map7A3NCBI
cM Map712.58NCBI
Cd177
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8189,467,926 - 89,488,490 (-)NCBIGRCr8
mRatBN7.2180,340,034 - 80,360,599 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl180,340,034 - 80,360,621 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx185,732,422 - 85,752,957 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0194,283,444 - 94,303,961 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0187,488,184 - 87,508,719 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0182,964,683 - 82,987,306 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl182,964,683 - 82,987,253 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0184,206,101 - 84,244,780 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4180,033,098 - 80,053,738 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera174,789,612 - 74,809,869 (-)NCBICelera
Cytogenetic Map1q21NCBI
Cd177
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555551,106,722 - 1,120,756 (+)NCBIChiLan1.0ChiLan1.0
CD177
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22049,504,794 - 49,515,439 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11951,304,519 - 51,382,077 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01940,287,083 - 40,295,914 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
Cd177
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934916,282,723 - 16,290,450 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004936706630,098 - 637,775 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CD177
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl650,246,365 - 50,255,713 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1650,246,165 - 50,255,935 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2646,102,450 - 46,115,835 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CD177
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1636,900,948 - 36,929,987 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl636,900,795 - 36,911,758 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607316,437,805 - 16,466,746 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cd177
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624907943,027 - 964,077 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CD177
68 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium
Low 6 6 6 6 6
Below cutoff 5 5 16 4 12 8 10 6

Sequence


RefSeq Acc Id: ENSCAFT00000007665   ⟹   ENSCAFP00000007099
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1111,693,005 - 111,698,742 (+)Ensembl
RefSeq Acc Id: XM_022425335   ⟹   XP_022281043
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11111,693,234 - 111,698,879 (+)NCBI
Dog10K_Boxer_Tasha1111,172,751 - 111,178,674 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038467982   ⟹   XP_038323910
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11111,891,326 - 111,897,264 (+)NCBI
RefSeq Acc Id: XM_038528712   ⟹   XP_038384640
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01112,409,530 - 112,415,468 (+)NCBI
RefSeq Acc Id: XM_038592989   ⟹   XP_038448917
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01111,525,114 - 111,531,052 (+)NCBI
RefSeq Acc Id: XM_038656799   ⟹   XP_038512727
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01112,303,259 - 112,309,197 (+)NCBI
RefSeq Acc Id: XP_022281043   ⟸   XM_022425335
- UniProtKB: A0A8P0SAD1 (UniProtKB/TrEMBL),   A0A8C0M8V5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000007099   ⟸   ENSCAFT00000007665
RefSeq Acc Id: XP_038323910   ⟸   XM_038467982
RefSeq Acc Id: XP_038448917   ⟸   XM_038592989
RefSeq Acc Id: XP_038512727   ⟸   XM_038656799
- UniProtKB: A0A8I3MHY1 (UniProtKB/TrEMBL),   A0A8C0M8V5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038384640   ⟸   XM_038528712
- UniProtKB: A0A8C0M8V5 (UniProtKB/TrEMBL),   A0A8I3MHY1 (UniProtKB/TrEMBL)
Protein Domains
UPAR/Ly6


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000004765 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030005004 UniProtKB/TrEMBL
  ENSCAFG00040014790 UniProtKB/TrEMBL
  ENSCAFG00845000474 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000007665.4 UniProtKB/TrEMBL
  ENSCAFT00030009210.1 UniProtKB/TrEMBL
  ENSCAFT00040027273.1 UniProtKB/TrEMBL
  ENSCAFT00845000769 ENTREZGENE
  ENSCAFT00845000769.1 UniProtKB/TrEMBL
Gene3D-CATH 2.10.60.10 UniProtKB/TrEMBL
InterPro LY6_UPA_recep-like UniProtKB/TrEMBL
  Snake_toxin-like_sf UniProtKB/TrEMBL
NCBI Gene CD177 ENTREZGENE
PANTHER CD177 ANTIGEN UniProtKB/TrEMBL
  CD177 ANTIGEN UniProtKB/TrEMBL
Pfam UPAR_LY6 UniProtKB/TrEMBL
Superfamily-SCOP SSF57302 UniProtKB/TrEMBL
UniProt A0A8C0M8V5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MHY1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0SAD1 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:38934 ENTREZGENE