NAB1 (NGFI-A binding protein 1) - Rat Genome Database

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Gene: NAB1 (NGFI-A binding protein 1) Canis lupus familiaris
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Symbol: NAB1
Name: NGFI-A binding protein 1
RGD ID: 12234055
Description: ENCODES a protein that exhibits transcription coregulator activity (inferred); INVOLVED IN endochondral ossification (inferred); myelination (inferred); negative regulation of DNA-templated transcription (inferred); ASSOCIATED WITH immunodeficiency 31B (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN nucleus (inferred); INTERACTS WITH enalapril; metoprolol; ranolazine
Type: protein-coding
RefSeq Status: MODEL
Previously known as: NGFI-A-binding protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1371,207,619 - 1,243,546 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl371,207,638 - 1,241,610 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha372,156,331 - 2,192,275 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0371,094,635 - 1,131,660 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl371,083,693 - 1,131,652 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1371,104,565 - 1,141,421 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0371,072,340 - 1,109,051 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0371,101,123 - 1,137,919 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
enalapril  (EXP)
metoprolol  (EXP)
ranolazine  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (IBA,IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
NAB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1371,207,619 - 1,243,546 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl371,207,638 - 1,241,610 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha372,156,331 - 2,192,275 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0371,094,635 - 1,131,660 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl371,083,693 - 1,131,652 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1371,104,565 - 1,141,421 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0371,072,340 - 1,109,051 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0371,101,123 - 1,137,919 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
NAB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382190,648,895 - 190,692,766 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2190,646,746 - 190,692,766 (+)Ensemblhg38GRCh38
GRCh372191,513,621 - 191,557,492 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362191,222,093 - 191,265,737 (+)NCBIBuild 36Build 36hg18NCBI36
Build 342191,339,353 - 191,382,997NCBI
Celera2185,108,599 - 185,152,244 (+)NCBICelera
Cytogenetic Map2q32.2NCBI
HuRef2183,373,298 - 183,416,985 (+)NCBIHuRef
CHM1_12191,519,756 - 191,563,428 (+)NCBICHM1_1
T2T-CHM13v2.02191,138,150 - 191,182,082 (+)NCBIT2T-CHM13v2.0
Nab1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39152,494,146 - 52,539,553 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl152,496,453 - 52,539,838 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38152,455,849 - 52,500,712 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl152,457,294 - 52,500,679 (-)Ensemblmm10GRCm38
MGSCv37152,512,693 - 52,557,292 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36152,402,423 - 52,444,902 (-)NCBIMGSCv36mm8
Celera152,994,293 - 53,038,893 (-)NCBICelera
Cytogenetic Map1C1.1NCBI
cM Map126.99NCBI
Nab1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8956,545,547 - 56,585,045 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl956,545,729 - 56,614,210 (+)EnsemblGRCr8
mRatBN7.2949,053,579 - 49,093,078 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl949,053,758 - 49,092,098 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx957,603,553 - 57,642,914 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0962,726,377 - 62,765,738 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0961,022,369 - 61,061,730 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0953,906,073 - 53,945,474 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl953,906,073 - 53,945,473 (+)Ensemblrn6Rnor6.0
Rnor_5.0953,571,213 - 53,610,613 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4946,084,090 - 46,124,259 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera946,720,081 - 46,759,582 (+)NCBICelera
RGSC_v3.1946,085,564 - 46,123,090 (+)NCBI
Cytogenetic Map9q22NCBI
Nab1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554038,456,572 - 8,487,749 (-)Ensembl
ChiLan1.0NW_0049554038,456,572 - 8,487,749 (-)NCBIChiLan1.0ChiLan1.0
NAB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21393,331,033 - 93,375,233 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B93,345,640 - 93,390,522 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B77,949,948 - 77,994,888 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B195,868,102 - 195,911,497 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B195,868,102 - 195,911,497 (+)EnsemblpanPan2panpan1.1
Nab1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303149,289,091 - 149,334,536 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365067,502,608 - 7,548,981 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365067,503,544 - 7,548,981 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NAB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1595,248,814 - 95,295,081 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11595,248,703 - 95,295,078 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215106,592,271 - 106,602,122 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NAB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11076,164,199 - 76,206,898 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1076,174,592 - 76,204,464 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666040123,268,481 - 123,311,813 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nab1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248545,393,525 - 5,423,580 (-)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in NAB1
214 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_022414991 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038447412 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038447413 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038463635 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038463636 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038521478 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038521479 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038585177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038585178 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038649586 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_545569 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000356 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000368 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCAFT00000015087   ⟹   ENSCAFP00000013960
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl371,207,638 - 1,241,610 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845044774   ⟹   ENSCAFP00845035086
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl371,083,693 - 1,131,652 (+)Ensembl
RefSeq Acc Id: XM_038447412   ⟹   XP_038303340
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0371,094,635 - 1,131,660 (+)NCBI
RefSeq Acc Id: XM_038447413   ⟹   XP_038303341
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0371,094,635 - 1,131,660 (+)NCBI
RefSeq Acc Id: XM_038463635   ⟹   XP_038319563
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha372,156,331 - 2,192,275 (+)NCBI
RefSeq Acc Id: XM_038463636   ⟹   XP_038319564
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha372,156,331 - 2,192,275 (+)NCBI
RefSeq Acc Id: XM_038521478   ⟹   XP_038377406
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1371,104,565 - 1,141,421 (+)NCBI
RefSeq Acc Id: XM_038521479   ⟹   XP_038377407
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1371,104,565 - 1,141,421 (+)NCBI
RefSeq Acc Id: XM_038585177   ⟹   XP_038441105
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0371,101,123 - 1,137,919 (+)NCBI
RefSeq Acc Id: XM_038585178   ⟹   XP_038441106
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0371,101,123 - 1,137,919 (+)NCBI
RefSeq Acc Id: XM_038649586   ⟹   XP_038505514
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0371,072,340 - 1,109,051 (+)NCBI
Ensembl Acc Id: ENSCAFP00000013960   ⟸   ENSCAFT00000015087
RefSeq Acc Id: XP_038377406   ⟸   XM_038521478
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038377407   ⟸   XM_038521479
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038505514   ⟸   XM_038649586
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038303340   ⟸   XM_038447412
- Peptide Label: isoform X2
- UniProtKB: A0A8C0JZX5 (UniProtKB/TrEMBL),   A0A8C0SN12 (UniProtKB/TrEMBL),   A0A8I3PKG7 (UniProtKB/TrEMBL),   A0A8C0K0Y5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038303341   ⟸   XM_038447413
- Peptide Label: isoform X1
- UniProtKB: A0A8C0K0Y5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038319563   ⟸   XM_038463635
- Peptide Label: isoform X2
- UniProtKB: A0A8C0JZX5 (UniProtKB/TrEMBL),   A0A8C0SN12 (UniProtKB/TrEMBL),   A0A8I3PKG7 (UniProtKB/TrEMBL),   A0A8C0K0Y5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038319564   ⟸   XM_038463636
- Peptide Label: isoform X1
- UniProtKB: A0A8C0K0Y5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038441105   ⟸   XM_038585177
- Peptide Label: isoform X2
- UniProtKB: A0A8C0JZX5 (UniProtKB/TrEMBL),   A0A8C0K0Y5 (UniProtKB/TrEMBL),   A0A8C0SN12 (UniProtKB/TrEMBL),   A0A8I3PKG7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038441106   ⟸   XM_038585178
- Peptide Label: isoform X1
- UniProtKB: A0A8C0K0Y5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845035086   ⟸   ENSCAFT00845044774
Protein Domains
NAB co-repressor   Nab N-terminal   Nab1 C-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000009496 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00040014396 UniProtKB/TrEMBL
  ENSCAFG00845025364 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000015087.5 UniProtKB/TrEMBL
  ENSCAFT00040026589.1 UniProtKB/TrEMBL
  ENSCAFT00845044774 ENTREZGENE
  ENSCAFT00845044774.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.120.2010 UniProtKB/TrEMBL
InterPro Nab1_C UniProtKB/TrEMBL
  NAB_co-repressor_dom UniProtKB/TrEMBL
  NAB_fam UniProtKB/TrEMBL
  Nab_N UniProtKB/TrEMBL
  NCD2_sf UniProtKB/TrEMBL
NCBI Gene NAB1 ENTREZGENE
PANTHER NGFI-A-BINDING PROTEIN 1 UniProtKB/TrEMBL
  PTHR12623 UniProtKB/TrEMBL
Pfam Nab1 UniProtKB/TrEMBL
  NCD1 UniProtKB/TrEMBL
  NCD2 UniProtKB/TrEMBL
UniProt A0A8C0JZX5 ENTREZGENE
  A0A8C0K0Y5 ENTREZGENE
  A0A8C0SN12 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3PKG7 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:43600 ENTREZGENE