APOA5 (apolipoprotein A5) - Rat Genome Database

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Gene: APOA5 (apolipoprotein A5) Canis lupus familiaris
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Symbol: APOA5
Name: apolipoprotein A5
RGD ID: 12231925
Description: ENCODES a protein that exhibits enzyme activator activity (ortholog); enzyme binding (ortholog); lipase activator activity (ortholog); INVOLVED IN acylglycerol homeostasis (ortholog); animal organ regeneration (ortholog); lipid transport (ortholog); PARTICIPATES IN lipoprotein metabolic pathway; ASSOCIATED WITH cerebral infarction (ortholog); Chromosome 11, Partial Trisomy 11q (ortholog); coronary artery disease (ortholog); FOUND IN extracellular region (ortholog); extracellular space (ortholog); low-density lipoprotein particle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: apolipoprotein A-V
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1516,774,117 - 16,777,535 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl516,774,501 - 16,777,768 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha516,826,641 - 16,829,696 (+)NCBI
ROS_Cfam_1.0516,721,181 - 16,724,236 (+)NCBI
ROS_Cfam_1.0 Ensembl516,721,199 - 16,723,685 (+)Ensembl
UMICH_Zoey_3.1516,858,043 - 16,861,098 (+)NCBI
UNSW_CanFamBas_1.0516,760,620 - 16,763,675 (+)NCBI
UU_Cfam_GSD_1.0516,803,753 - 16,806,810 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
APOA5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1516,774,117 - 16,777,535 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl516,774,501 - 16,777,768 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha516,826,641 - 16,829,696 (+)NCBI
ROS_Cfam_1.0516,721,181 - 16,724,236 (+)NCBI
ROS_Cfam_1.0 Ensembl516,721,199 - 16,723,685 (+)Ensembl
UMICH_Zoey_3.1516,858,043 - 16,861,098 (+)NCBI
UNSW_CanFamBas_1.0516,760,620 - 16,763,675 (+)NCBI
UU_Cfam_GSD_1.0516,803,753 - 16,806,810 (+)NCBI
APOA5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811116,789,367 - 116,792,420 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl11116,789,367 - 116,792,420 (-)EnsemblGRCh38hg38GRCh38
GRCh3711116,660,083 - 116,663,136 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611116,165,296 - 116,167,794 (-)NCBINCBI36hg18NCBI36
Build 3411116,165,296 - 116,167,794NCBI
Celera11113,815,476 - 113,818,526 (-)NCBI
Cytogenetic Map11q23.3NCBI
HuRef11112,592,079 - 112,595,129 (-)NCBIHuRef
CHM1_111116,544,726 - 116,547,776 (-)NCBICHM1_1
T2T-CHM13v2.011116,803,991 - 116,807,044 (-)NCBI
Apoa5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39946,179,906 - 46,183,219 (+)NCBIGRCm39mm39
GRCm39 Ensembl946,179,931 - 46,183,217 (+)Ensembl
GRCm38946,268,608 - 46,271,921 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl946,268,633 - 46,271,919 (+)EnsemblGRCm38mm10GRCm38
MGSCv37946,076,691 - 46,080,002 (+)NCBIGRCm37mm9NCBIm37
MGSCv36946,019,603 - 46,022,914 (+)NCBImm8
Celera943,557,616 - 43,560,927 (+)NCBICelera
Cytogenetic Map9A5.2NCBI
Apoa5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2846,561,180 - 46,563,818 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl846,561,229 - 46,563,816 (+)Ensembl
Rnor_6.0850,559,079 - 50,561,720 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl850,559,126 - 50,561,736 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0849,185,041 - 49,187,682 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4849,253,538 - 49,255,777 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1849,265,341 - 49,267,579 (+)NCBI
Celera846,142,946 - 46,145,584 (+)NCBICelera
Cytogenetic Map8q22NCBI
Apoa5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541218,129,603 - 18,131,115 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541218,128,861 - 18,131,752 (-)NCBIChiLan1.0ChiLan1.0
APOA5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.111115,559,231 - 115,562,286 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11115,559,231 - 115,562,286 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v011111,625,403 - 111,627,932 (-)NCBIMhudiblu_PPA_v0panPan3
Apoa5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494799,147,591 - 99,149,935 (-)NCBI
SpeTri2.0NW_0049365422,069,683 - 2,071,344 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
APOA5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1944,177,834 - 44,180,880 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2949,251,674 - 49,254,883 (-)NCBISscrofa10.2Sscrofa10.2susScr3
APOA5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11108,154,880 - 108,158,998 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1108,155,641 - 108,157,375 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604317,891,675 - 17,894,161 (+)NCBIVero_WHO_p1.0
Apoa5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478412,213,744 - 12,216,026 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462478412,213,205 - 12,216,039 (-)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 6 6 6
Low 1
Below cutoff 5 5 16 6 5 6 12 8 10 6

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000021156   ⟹   ENSCAFP00000019647
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl516,774,501 - 16,777,768 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845007754   ⟹   ENSCAFP00845006140
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl516,721,199 - 16,723,685 (+)Ensembl
RefSeq Acc Id: XM_005619731   ⟹   XP_005619788
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1516,774,117 - 16,777,535 (+)NCBI
Dog10K_Boxer_Tasha516,826,641 - 16,829,696 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038474928   ⟹   XP_038330856
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1516,858,043 - 16,861,098 (+)NCBI
RefSeq Acc Id: XM_038474930   ⟹   XP_038330858
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1516,858,043 - 16,861,098 (+)NCBI
RefSeq Acc Id: XM_038536055   ⟹   XP_038391983
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0516,803,753 - 16,806,810 (+)NCBI
RefSeq Acc Id: XM_038600248   ⟹   XP_038456176
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0516,760,620 - 16,763,675 (+)NCBI
RefSeq Acc Id: XM_038600249   ⟹   XP_038456177
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0516,760,620 - 16,763,675 (+)NCBI
RefSeq Acc Id: XM_038664798   ⟹   XP_038520726
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0516,721,181 - 16,724,236 (+)NCBI
RefSeq Acc Id: XM_038664799   ⟹   XP_038520727
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0516,721,181 - 16,724,236 (+)NCBI
RefSeq Acc Id: XM_546511   ⟹   XP_546511
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1516,774,120 - 16,777,535 (+)NCBI
Dog10K_Boxer_Tasha516,826,641 - 16,829,696 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_005619788   ⟸   XM_005619731
- Sequence:
RefSeq Acc Id: XP_546511   ⟸   XM_546511
- Sequence:
RefSeq Acc Id: ENSCAFP00000019647   ⟸   ENSCAFT00000021156
RefSeq Acc Id: XP_038330858   ⟸   XM_038474930
RefSeq Acc Id: XP_038330856   ⟸   XM_038474928
RefSeq Acc Id: XP_038456177   ⟸   XM_038600249
RefSeq Acc Id: XP_038456176   ⟸   XM_038600248
RefSeq Acc Id: XP_038520727   ⟸   XM_038664799
RefSeq Acc Id: XP_038520726   ⟸   XM_038664798
RefSeq Acc Id: XP_038391983   ⟸   XM_038536055
RefSeq Acc Id: ENSCAFP00845006140   ⟸   ENSCAFT00845007754

Promoters
RGD ID:13683147
Promoter ID:EPDNEW_C1214
Type:multiple initiation site
Name:APOA5_1
Description:apolipoprotein A5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1516,774,973 - 16,775,033EPDNEW
Damaging Variants


Assembly: CanFam3.1

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
5 16776277 16776278 G A snv Siberian Husky (SY046), Alaskan Husky (SY001)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000013327 Ensembl
  ENSCAFG00845004306 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00845006140 ENTREZGENE
  ENSCAFP00845006140.1 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00845007754 ENTREZGENE
  ENSCAFT00845007754.1 UniProtKB/TrEMBL
NCBI Gene APOA5 ENTREZGENE
UniProt A0A8I3MRY5_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:37993 ENTREZGENE