DCAF13 (DDB1 and CUL4 associated factor 13) - Rat Genome Database

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Gene: DCAF13 (DDB1 and CUL4 associated factor 13) Canis lupus familiaris
Analyze
Symbol: DCAF13
Name: DDB1 and CUL4 associated factor 13
RGD ID: 12230491
Description: ENCODES a protein that exhibits nuclear estrogen receptor binding (inferred); ubiquitin-like ligase-substrate adaptor activity (inferred); INVOLVED IN decidualization (inferred); epigenetic programming in the zygotic pronuclei (inferred); oocyte growth (inferred); ASSOCIATED WITH Cohen syndrome (ortholog); FOUND IN cell junction (inferred); centrosome (inferred); Cul4-RING E3 ubiquitin ligase complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: DDB1- and CUL4-associated factor 13; WD repeats and SOF1 domain containing; WDSOF1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1134,835,147 - 4,860,706 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl134,834,958 - 4,860,247 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha134,838,774 - 4,863,783 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0134,999,335 - 5,024,396 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl134,999,453 - 5,025,111 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1134,839,637 - 4,864,677 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0134,957,559 - 4,982,592 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0134,970,339 - 4,995,381 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
DCAF13
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1134,835,147 - 4,860,706 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl134,834,958 - 4,860,247 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha134,838,774 - 4,863,783 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0134,999,335 - 5,024,396 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl134,999,453 - 5,025,111 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1134,839,637 - 4,864,677 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0134,957,559 - 4,982,592 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0134,970,339 - 4,995,381 (+)NCBIUU_Cfam_GSD_1.0
DCAF13
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388103,415,386 - 103,443,453 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8103,414,714 - 103,443,453 (+)EnsemblGRCh38hg38GRCh38
GRCh378104,427,614 - 104,455,681 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 368104,496,118 - 104,524,376 (+)NCBINCBI36Build 36hg18NCBI36
Celera8100,613,481 - 100,642,207 (+)NCBICelera
Cytogenetic Map8q22.3NCBI
HuRef899,627,291 - 99,656,018 (+)NCBIHuRef
CHM1_18104,467,741 - 104,496,445 (+)NCBICHM1_1
T2T-CHM13v2.08104,543,035 - 104,571,087 (+)NCBIT2T-CHM13v2.0
Dcaf13
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391538,976,300 - 39,010,251 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1538,976,260 - 39,010,251 (+)EnsemblGRCm39 Ensembl
GRCm381539,112,874 - 39,146,856 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1539,112,865 - 39,146,856 (+)EnsemblGRCm38mm10GRCm38
MGSCv371538,944,420 - 38,978,402 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361538,943,006 - 38,976,930 (+)NCBIMGSCv36mm8
Celera1539,600,285 - 39,634,269 (+)NCBICelera
Cytogenetic Map15B3.1NCBI
cM Map1515.42NCBI
Dcaf13
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8772,045,828 - 72,081,039 (+)NCBIGRCr8
mRatBN7.2770,160,983 - 70,196,142 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl770,160,941 - 70,196,142 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx772,034,138 - 72,069,389 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0774,236,651 - 74,271,908 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0774,104,737 - 74,139,984 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0778,005,232 - 78,040,220 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl778,005,232 - 78,040,214 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0778,209,274 - 78,244,263 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4774,668,602 - 74,703,968 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1774,689,351 - 74,724,698 (+)NCBI
Celera767,217,401 - 67,252,558 (+)NCBICelera
Cytogenetic Map7q31NCBI
Dcaf13
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541727,544,242 - 27,569,715 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541727,545,128 - 27,567,829 (+)NCBIChiLan1.0ChiLan1.0
DCAF13
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27120,780,993 - 120,809,175 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1896,317,081 - 96,345,064 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08100,070,628 - 100,098,885 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18102,226,116 - 102,254,900 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8102,226,116 - 102,254,900 (+)Ensemblpanpan1.1panPan2
Dcaf13
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530332,895,023 - 32,931,004 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647040,320,073 - 40,356,993 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647040,321,103 - 40,357,001 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DCAF13
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl433,672,871 - 33,704,573 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1433,672,867 - 33,704,888 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2436,445,544 - 36,477,231 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DCAF13
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1898,271,304 - 98,297,950 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603942,303,922 - 42,330,346 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dcaf13
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476319,955,408 - 19,980,620 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476319,955,368 - 19,980,480 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in DCAF13
232 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000001031   ⟹   ENSCAFP00000000945
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl134,834,958 - 4,860,247 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845015181   ⟹   ENSCAFP00845011787
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl134,999,453 - 5,008,054 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845015215   ⟹   ENSCAFP00845011815
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl134,999,453 - 5,008,054 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845015252   ⟹   ENSCAFP00845011845
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl134,999,459 - 5,025,111 (+)Ensembl
RefSeq Acc Id: XM_005627845   ⟹   XP_005627902
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1134,837,668 - 4,860,706 (+)NCBI
Dog10K_Boxer_Tasha134,841,320 - 4,863,783 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038493004   ⟹   XP_038348932
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1134,839,637 - 4,864,677 (+)NCBI
RefSeq Acc Id: XM_038493005   ⟹   XP_038348933
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1134,842,183 - 4,864,677 (+)NCBI
RefSeq Acc Id: XM_038555264   ⟹   XP_038411192
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0134,970,339 - 4,995,381 (+)NCBI
RefSeq Acc Id: XM_038555265   ⟹   XP_038411193
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0134,972,884 - 4,995,381 (+)NCBI
RefSeq Acc Id: XM_038619161   ⟹   XP_038475089
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0134,957,559 - 4,982,592 (+)NCBI
RefSeq Acc Id: XM_038619162   ⟹   XP_038475090
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0134,960,105 - 4,982,592 (+)NCBI
RefSeq Acc Id: XM_038684777   ⟹   XP_038540705
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0134,999,335 - 5,024,396 (+)NCBI
RefSeq Acc Id: XM_038684778   ⟹   XP_038540706
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0135,001,881 - 5,024,396 (+)NCBI
RefSeq Acc Id: XM_532299   ⟹   XP_532299
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1134,835,147 - 4,860,251 (+)NCBI
Dog10K_Boxer_Tasha134,838,774 - 4,863,783 (+)NCBI
Sequence:
RefSeq Acc Id: XP_532299   ⟸   XM_532299
- Peptide Label: isoform X1
- UniProtKB: A0A8C0NZT7 (UniProtKB/TrEMBL),   A0A8C0QUA3 (UniProtKB/TrEMBL),   A0A8I3N5L1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005627902   ⟸   XM_005627845
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSCAFP00000000945   ⟸   ENSCAFT00000001031
RefSeq Acc Id: XP_038348932   ⟸   XM_038493004
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038348933   ⟸   XM_038493005
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038475089   ⟸   XM_038619161
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038475090   ⟸   XM_038619162
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038540705   ⟸   XM_038684777
- Peptide Label: isoform X1
- UniProtKB: A0A8C0NZT7 (UniProtKB/TrEMBL),   A0A8C0QUA3 (UniProtKB/TrEMBL),   A0A8I3N5L1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038540706   ⟸   XM_038684778
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038411192   ⟸   XM_038555264
- Peptide Label: isoform X1
- UniProtKB: A0A8C0NZT7 (UniProtKB/TrEMBL),   A0A8C0QUA3 (UniProtKB/TrEMBL),   A0A8I3N5L1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038411193   ⟸   XM_038555265
- Peptide Label: isoform X2
Ensembl Acc Id: ENSCAFP00845011815   ⟸   ENSCAFT00845015215
Ensembl Acc Id: ENSCAFP00845011787   ⟸   ENSCAFT00845015181
Ensembl Acc Id: ENSCAFP00845011845   ⟸   ENSCAFT00845015252
Protein Domains
Sof1-like protein

Promoters
RGD ID:13685566
Promoter ID:EPDNEW_C3636
Type:multiple initiation site
Name:DCAF13_1
Description:DDB1 and CUL4 associated factor 13
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1134,835,253 - 4,835,313EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000000663 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030021633 UniProtKB/TrEMBL
  ENSCAFG00040006300 UniProtKB/TrEMBL
  ENSCAFG00845008632 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000001031.5 UniProtKB/TrEMBL
  ENSCAFT00000094792.1 UniProtKB/TrEMBL
  ENSCAFT00000107552.1 UniProtKB/TrEMBL
  ENSCAFT00030039893.1 UniProtKB/TrEMBL
  ENSCAFT00030039971.1 UniProtKB/TrEMBL
  ENSCAFT00030039994.1 UniProtKB/TrEMBL
  ENSCAFT00040011874.1 UniProtKB/TrEMBL
  ENSCAFT00040011957.1 UniProtKB/TrEMBL
  ENSCAFT00040011975.1 UniProtKB/TrEMBL
  ENSCAFT00845015181.1 UniProtKB/TrEMBL
  ENSCAFT00845015215.1 UniProtKB/TrEMBL
  ENSCAFT00845015252 ENTREZGENE
  ENSCAFT00845015252.1 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
InterPro Sof1 UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_CS UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
  WD_repeat_DCAF13/WDSOF1 UniProtKB/TrEMBL
NCBI Gene DCAF13 ENTREZGENE
PANTHER DDB1- AND CUL4-ASSOCIATED FACTOR 13 UniProtKB/TrEMBL
  U3 SMALL NUCLEOLAR RNA U3 SNORNA ASSOCIATED PROTEIN UniProtKB/TrEMBL
Pfam Sof1 UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
PROSITE WD_REPEATS_1 UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
SMART WD40 UniProtKB/TrEMBL
Superfamily-SCOP SSF50978 UniProtKB/TrEMBL
UniProt A0A8C0NZT7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0P785_CANLF UniProtKB/TrEMBL
  A0A8C0QG00_CANLF UniProtKB/TrEMBL
  A0A8C0QUA3 ENTREZGENE
  A0A8I3N5L1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NBN4_CANLF UniProtKB/TrEMBL
  A0A8I3RUQ1_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:39791 ENTREZGENE