NOTCH4 (notch receptor 4) - Rat Genome Database

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Gene: NOTCH4 (notch receptor 4) Canis lupus familiaris
Analyze
Symbol: NOTCH4
Name: notch receptor 4
RGD ID: 12229674
Description: ENCODES a protein that exhibits cis-regulatory region sequence-specific DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); INVOLVED IN branching involved in blood vessel morphogenesis (ortholog); endothelial cell differentiation (ortholog); endothelial cell morphogenesis (ortholog); PARTICIPATES IN Notch signaling pathway; ASSOCIATED WITH AIDS-Associated Nephropathy (ortholog); alopecia areata (ortholog); Animal Mammary Neoplasms (ortholog); FOUND IN cell surface (ortholog); cytoplasmic vesicle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: neurogenic locus notch homolog protein 4; notch 4; Notch homolog 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1121,585,249 - 1,608,721 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl121,587,918 - 1,607,760 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha121,720,443 - 1,742,455 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0121,724,977 - 1,746,984 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1121,587,999 - 1,609,976 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0121,653,597 - 1,675,505 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0121,719,919 - 1,741,905 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
NOTCH4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1121,585,249 - 1,608,721 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl121,587,918 - 1,607,760 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha121,720,443 - 1,742,455 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0121,724,977 - 1,746,984 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1121,587,999 - 1,609,976 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0121,653,597 - 1,675,505 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0121,719,919 - 1,741,905 (-)NCBIUU_Cfam_GSD_1.0
NOTCH4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38632,194,843 - 32,224,067 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl632,194,843 - 32,224,067 (-)EnsemblGRCh38hg38GRCh38
GRCh37632,162,620 - 32,191,844 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36632,270,598 - 32,299,822 (-)NCBINCBI36Build 36hg18NCBI36
Build 34632,270,598 - 32,299,822NCBI
Celera633,729,664 - 33,758,884 (-)NCBICelera
Cytogenetic Map6p21.32NCBI
HuRef631,916,815 - 31,946,041 (-)NCBIHuRef
CHM1_1632,165,104 - 32,194,322 (-)NCBICHM1_1
T2T-CHM13v2.0632,048,032 - 32,077,265 (-)NCBIT2T-CHM13v2.0
Notch4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391734,783,257 - 34,807,517 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1734,783,242 - 34,807,477 (+)EnsemblGRCm39 Ensembl
GRCm381734,564,286 - 34,588,543 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1734,564,268 - 34,588,503 (+)EnsemblGRCm38mm10GRCm38
MGSCv371734,701,240 - 34,725,488 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361734,172,386 - 34,196,552 (+)NCBIMGSCv36mm8
Celera1737,659,444 - 37,683,703 (+)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1718.15NCBI
Notch4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8204,164,969 - 4,189,072 (-)NCBIGRCr8
mRatBN7.2204,160,362 - 4,184,466 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl204,160,445 - 4,184,465 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx204,867,047 - 4,890,265 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0204,228,799 - 4,252,017 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0204,759,694 - 4,786,711 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0204,329,794 - 4,353,868 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl204,329,811 - 4,353,785 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0206,409,125 - 6,433,141 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4204,263,205 - 4,287,312 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1204,263,431 - 4,287,539 (-)NCBI
Celera203,846,498 - 3,869,836 (+)NCBICelera
Cytogenetic Map20p12NCBI
Notch4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955437658,076 - 679,338 (-)NCBIChiLan1.0ChiLan1.0
NOTCH4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2546,657,915 - 46,687,084 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1642,619,989 - 42,648,574 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0631,842,233 - 31,871,412 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1632,722,112 - 32,750,978 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl632,722,112 - 32,750,978 (-)Ensemblpanpan1.1panPan2
Notch4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494636,152,409 - 36,174,550 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049367271,386,842 - 1,409,823 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NOTCH4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl724,231,293 - 24,256,281 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1724,231,293 - 24,256,281 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2728,052,185 - 28,077,374 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NOTCH4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11739,806,864 - 39,837,101 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1739,808,035 - 39,837,365 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604432,094,646 - 32,124,232 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Notch4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475424,108,661 - 24,128,053 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in NOTCH4
320 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 15 6 10 6
Low 5 7 6 6 6 6 6 6 8
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_022425782 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038491421 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038553638 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038553639 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038553640 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038553641 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038553642 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038553643 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038617515 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038675216 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038675220 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038675223 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038675227 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038675232 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038675239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038683077 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000123 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000357 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSCAFT00000001228   ⟹   ENSCAFP00000001124
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl121,587,918 - 1,607,760 (-)Ensembl
RefSeq Acc Id: XM_038491421   ⟹   XP_038347349
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1121,587,999 - 1,609,976 (-)NCBI
RefSeq Acc Id: XM_038553638   ⟹   XP_038409566
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0121,719,919 - 1,741,905 (-)NCBI
RefSeq Acc Id: XM_038553639   ⟹   XP_038409567
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0121,719,919 - 1,741,905 (-)NCBI
RefSeq Acc Id: XM_038553640   ⟹   XP_038409568
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0121,719,919 - 1,741,905 (-)NCBI
RefSeq Acc Id: XM_038553641   ⟹   XP_038409569
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0121,719,919 - 1,741,905 (-)NCBI
RefSeq Acc Id: XM_038553642   ⟹   XP_038409570
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0121,721,415 - 1,741,905 (-)NCBI
RefSeq Acc Id: XM_038553643   ⟹   XP_038409571
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0121,721,935 - 1,741,905 (-)NCBI
RefSeq Acc Id: XM_038617515   ⟹   XP_038473443
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0121,653,597 - 1,675,505 (-)NCBI
RefSeq Acc Id: XM_038675216   ⟹   XP_038531144
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha121,720,443 - 1,742,455 (-)NCBI
RefSeq Acc Id: XM_038675220   ⟹   XP_038531148
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha121,720,443 - 1,742,455 (-)NCBI
RefSeq Acc Id: XM_038675223   ⟹   XP_038531151
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha121,720,443 - 1,742,455 (-)NCBI
RefSeq Acc Id: XM_038675227   ⟹   XP_038531155
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha121,720,443 - 1,742,455 (-)NCBI
RefSeq Acc Id: XM_038675232   ⟹   XP_038531160
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha121,721,953 - 1,742,455 (-)NCBI
RefSeq Acc Id: XM_038675239   ⟹   XP_038531167
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha121,722,473 - 1,742,455 (-)NCBI
RefSeq Acc Id: XM_038683077   ⟹   XP_038539005
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0121,724,977 - 1,746,984 (-)NCBI
RefSeq Acc Id: ENSCAFP00000001124   ⟸   ENSCAFT00000001228
RefSeq Acc Id: XP_038347349   ⟸   XM_038491421
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038473443   ⟸   XM_038617515
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038539005   ⟸   XM_038683077
- Peptide Label: isoform X1
- UniProtKB: A0A8C0NLH1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038531151   ⟸   XM_038675223
- Peptide Label: isoform X7
- UniProtKB: A0A8C0NLH1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038531155   ⟸   XM_038675227
- Peptide Label: isoform X8
- UniProtKB: A0A8P0PLS3 (UniProtKB/TrEMBL),   A0A8C0NLH1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038531148   ⟸   XM_038675220
- Peptide Label: isoform X6
- UniProtKB: A0A8C0NLH1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038531144   ⟸   XM_038675216
- Peptide Label: isoform X1
- UniProtKB: A0A8C0NLH1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038531160   ⟸   XM_038675232
- Peptide Label: isoform X9
- UniProtKB: A0A8C0NLH1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038531167   ⟸   XM_038675239
- Peptide Label: isoform X9
- UniProtKB: A0A8C0NLH1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038409568   ⟸   XM_038553640
- Peptide Label: isoform X3
- UniProtKB: A0A8C0NLH1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038409569   ⟸   XM_038553641
- Peptide Label: isoform X4
- UniProtKB: A0A8C0NLH1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038409567   ⟸   XM_038553639
- Peptide Label: isoform X2
- UniProtKB: A0A8C0NLH1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038409566   ⟸   XM_038553638
- Peptide Label: isoform X1
- UniProtKB: A0A8C0NLH1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038409570   ⟸   XM_038553642
- Peptide Label: isoform X5
- UniProtKB: A0A8C0NLH1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038409571   ⟸   XM_038553643
- Peptide Label: isoform X5
- UniProtKB: A0A8C0NLH1 (UniProtKB/TrEMBL)
Protein Domains
EGF-like   LNR

Promoters
RGD ID:13685358
Promoter ID:EPDNEW_C3426
Type:single initiation site
Name:NOTCH4_1
Description:notch 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1121,608,714 - 1,608,774EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000000791 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030016305 UniProtKB/TrEMBL
  ENSCAFG00845016542 ENTREZGENE
Ensembl Transcript ENSCAFT00000001228.6 UniProtKB/TrEMBL
  ENSCAFT00000100131.1 UniProtKB/TrEMBL
  ENSCAFT00000109084.1 UniProtKB/TrEMBL
  ENSCAFT00030030269.1 UniProtKB/TrEMBL
  ENSCAFT00845029482 ENTREZGENE
Gene3D-CATH 1.25.40.20 UniProtKB/TrEMBL
  3.30.300.320 UniProtKB/TrEMBL
  3.30.70.3310 UniProtKB/TrEMBL
  Laminin UniProtKB/TrEMBL
InterPro Ankyrin_rpt UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/TrEMBL
  EGF-like_Ca-bd_dom UniProtKB/TrEMBL
  EGF-like_CS UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/TrEMBL
  EGF-type_Asp/Asn_hydroxyl_site UniProtKB/TrEMBL
  EGF_Ca-bd_CS UniProtKB/TrEMBL
  Growth_fac_rcpt_cys_sf UniProtKB/TrEMBL
  Notch UniProtKB/TrEMBL
  Notch-like_dom_sf UniProtKB/TrEMBL
  Notch_4 UniProtKB/TrEMBL
  Notch_dom UniProtKB/TrEMBL
  Notch_NOD_dom UniProtKB/TrEMBL
  Notch_NODP_dom UniProtKB/TrEMBL
NCBI Gene NOTCH4 ENTREZGENE
PANTHER CRUMBS FAMILY MEMBER UniProtKB/TrEMBL
  CYTOCHROME C OXIDASE POLYPEPTIDE VIC-2 UniProtKB/TrEMBL
  DROSOPHILA CRUMBS HOMOLOG UniProtKB/TrEMBL
  NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1 UniProtKB/TrEMBL
  NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1 UniProtKB/TrEMBL
Pfam Ank UniProtKB/TrEMBL
  Ank_2 UniProtKB/TrEMBL
  EGF UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  hEGF UniProtKB/TrEMBL
  NOD UniProtKB/TrEMBL
  NODP UniProtKB/TrEMBL
  Notch UniProtKB/TrEMBL
PIRSF Notch UniProtKB/TrEMBL
PRINTS LNOTCHREPEAT UniProtKB/TrEMBL
  NOTCH UniProtKB/TrEMBL
  NOTCH4 UniProtKB/TrEMBL
PROSITE ANK_REP_REGION UniProtKB/TrEMBL
  ANK_REPEAT UniProtKB/TrEMBL
  ASX_HYDROXYL UniProtKB/TrEMBL
  EGF_1 UniProtKB/TrEMBL
  EGF_2 UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  LNR UniProtKB/TrEMBL
SMART ANK UniProtKB/TrEMBL
  EGF UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  NOD UniProtKB/TrEMBL
  NODP UniProtKB/TrEMBL
  SM00004 UniProtKB/TrEMBL
Superfamily-SCOP Ankyrin repeat UniProtKB/TrEMBL
  EGF/Laminin UniProtKB/TrEMBL
  Growth factor receptor domain UniProtKB/TrEMBL
  Notch domain UniProtKB/TrEMBL
UniProt A0A8C0NLH1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0N414_CANLF UniProtKB/TrEMBL
  A0A8P0PLS3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0TUQ0_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:43900 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-01-15 NOTCH4  notch receptor 4    notch 4  Symbol and/or name change 5135510 APPROVED