ENOSF1 (enolase superfamily member 1) - Rat Genome Database

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Gene: ENOSF1 (enolase superfamily member 1) Canis lupus familiaris
Analyze
Symbol: ENOSF1
Name: enolase superfamily member 1
RGD ID: 12228526
Description: ENCODES a protein that exhibits hydro-lyase activity (inferred); L-fuconate dehydratase activity (inferred); magnesium ion binding (inferred); INVOLVED IN amino acid catabolic process (inferred); carbohydrate catabolic process (inferred); ASSOCIATED WITH autistic disorder (ortholog); Drug-Related Side Effects and Adverse Reactions (ortholog); dyskeratosis congenita (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: mitochondrial enolase superfamily member 1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1767,498,425 - 67,527,534 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl767,498,432 - 67,527,490 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha766,951,922 - 66,981,217 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0767,564,375 - 67,593,532 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl767,564,384 - 67,593,945 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1767,241,113 - 67,270,262 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0767,252,565 - 67,281,837 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0767,554,473 - 67,583,772 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ENOSF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1767,498,425 - 67,527,534 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl767,498,432 - 67,527,490 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha766,951,922 - 66,981,217 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0767,564,375 - 67,593,532 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl767,564,384 - 67,593,945 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1767,241,113 - 67,270,262 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0767,252,565 - 67,281,837 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0767,554,473 - 67,583,772 (-)NCBIUU_Cfam_GSD_1.0
ENOSF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3818662,986 - 712,630 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl18670,318 - 712,662 (-)EnsemblGRCh38hg38GRCh38
GRCh3718670,318 - 712,630 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3618663,914 - 702,642 (-)NCBINCBI36Build 36hg18NCBI36
Build 3418663,914 - 702,642NCBI
Celera18546,854 - 586,968 (-)NCBICelera
Cytogenetic Map18p11.32NCBI
HuRef18630,762 - 673,007 (-)NCBIHuRef
CHM1_118669,517 - 712,030 (-)NCBICHM1_1
T2T-CHM13v2.018824,595 - 867,052 (-)NCBIT2T-CHM13v2.0
Enosf1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.29113,275,267 - 113,314,842 (+)NCBImRatBN7.2mRatBN7.2
Cytogenetic Map9q38NCBI
Enosf1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554029,266,192 - 9,295,115 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554029,266,198 - 9,297,897 (+)NCBIChiLan1.0ChiLan1.0
ENOSF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21737,788,946 - 37,828,908 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11823,481,529 - 23,521,587 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01813,613,425 - 13,652,583 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11817,256,413 - 17,298,363 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1817,256,489 - 17,294,287 (+)Ensemblpanpan1.1panPan2
Enosf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494463,784,690 - 63,824,346 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493655012,899 - 31,390 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ENOSF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6105,613,215 - 105,645,113 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16105,613,211 - 105,642,533 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
ENOSF1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11860,042,711 - 60,080,954 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1860,043,096 - 60,080,904 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605034,833,697 - 34,872,504 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Enosf1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477011,150,438 - 11,179,497 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477011,150,044 - 11,179,506 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ENOSF1
445 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 12 6 6 1 6
Low 5 5 10 6 6 6 11 3 4 6
Below cutoff 5

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000029159   ⟹   ENSCAFP00000027117
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl767,498,432 - 67,527,490 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000062541   ⟹   ENSCAFP00000062201
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl767,498,432 - 67,527,490 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000080013   ⟹   ENSCAFP00000055594
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl767,498,432 - 67,522,475 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845003711   ⟹   ENSCAFP00845002950
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl767,564,384 - 67,593,945 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845003736   ⟹   ENSCAFP00845002967
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl767,564,384 - 67,593,945 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845003771   ⟹   ENSCAFP00845002997
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl767,564,384 - 67,593,482 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845003780   ⟹   ENSCAFP00845003005
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl767,564,384 - 67,588,466 (-)Ensembl
RefSeq Acc Id: XM_014115531   ⟹   XP_013971006
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1767,498,425 - 67,522,475 (-)NCBI
Dog10K_Boxer_Tasha766,951,922 - 66,976,159 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038482265   ⟹   XP_038338193
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1767,241,113 - 67,270,262 (-)NCBI
RefSeq Acc Id: XM_038482266   ⟹   XP_038338194
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1767,241,113 - 67,265,205 (-)NCBI
RefSeq Acc Id: XM_038543701   ⟹   XP_038399629
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0767,554,473 - 67,583,772 (-)NCBI
RefSeq Acc Id: XM_038543702   ⟹   XP_038399630
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0767,554,473 - 67,578,718 (-)NCBI
RefSeq Acc Id: XM_038607826   ⟹   XP_038463754
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0767,252,565 - 67,281,837 (-)NCBI
RefSeq Acc Id: XM_038607827   ⟹   XP_038463755
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0767,252,565 - 67,276,785 (-)NCBI
RefSeq Acc Id: XM_038672508   ⟹   XP_038528436
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0767,564,375 - 67,593,532 (-)NCBI
RefSeq Acc Id: XM_038672510   ⟹   XP_038528438
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0767,564,375 - 67,588,466 (-)NCBI
RefSeq Acc Id: XM_843532   ⟹   XP_848625
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1767,498,425 - 67,527,534 (-)NCBI
Dog10K_Boxer_Tasha766,951,922 - 66,981,217 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_848625   ⟸   XM_843532
- Peptide Label: isoform X1
- UniProtKB: A0A8C0PQK6 (UniProtKB/TrEMBL),   A0A8C0KZT4 (UniProtKB/TrEMBL),   A0A8C0RKZ7 (UniProtKB/TrEMBL),   A0A8P0NJK4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013971006   ⟸   XM_014115531
- Peptide Label: isoform X2
- UniProtKB: A0A8C0Q1E6 (UniProtKB/TrEMBL),   A0A8P0T7U2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000055594   ⟸   ENSCAFT00000080013
RefSeq Acc Id: ENSCAFP00000027117   ⟸   ENSCAFT00000029159
RefSeq Acc Id: ENSCAFP00000062201   ⟸   ENSCAFT00000062541
RefSeq Acc Id: XP_038338193   ⟸   XM_038482265
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038338194   ⟸   XM_038482266
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038463754   ⟸   XM_038607826
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038463755   ⟸   XM_038607827
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038528436   ⟸   XM_038672508
- Peptide Label: isoform X1
- UniProtKB: A0A8C0PQK6 (UniProtKB/TrEMBL),   A0A8I3MKD4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038528438   ⟸   XM_038672510
- Peptide Label: isoform X2
- UniProtKB: A0A8I3RS04 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038399629   ⟸   XM_038543701
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KZT4 (UniProtKB/TrEMBL),   A0A8C0PQK6 (UniProtKB/TrEMBL),   A0A8C0RKZ7 (UniProtKB/TrEMBL),   A0A8P0NJK4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038399630   ⟸   XM_038543702
- Peptide Label: isoform X2
- UniProtKB: A0A8C0Q1E6 (UniProtKB/TrEMBL),   A0A8P0T7U2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845002997   ⟸   ENSCAFT00845003771
RefSeq Acc Id: ENSCAFP00845003005   ⟸   ENSCAFT00845003780
RefSeq Acc Id: ENSCAFP00845002950   ⟸   ENSCAFT00845003711
RefSeq Acc Id: ENSCAFP00845002967   ⟸   ENSCAFT00845003736
Protein Domains
Mandelate racemase/muconate lactonizing enzyme C-

Promoters
RGD ID:13684094
Promoter ID:EPDNEW_C2160
Type:multiple initiation site
Name:ENOSF1_1
Description:enolase superfamily member 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1767,527,480 - 67,527,540EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000018351 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030015403 UniProtKB/TrEMBL
  ENSCAFG00040001250 UniProtKB/TrEMBL
  ENSCAFG00845002065 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000029159.5 UniProtKB/TrEMBL
  ENSCAFT00000080013.2 UniProtKB/TrEMBL
  ENSCAFT00030028705.1 UniProtKB/TrEMBL
  ENSCAFT00030028840.1 UniProtKB/TrEMBL
  ENSCAFT00040002375.1 UniProtKB/TrEMBL
  ENSCAFT00040002429.1 UniProtKB/TrEMBL
  ENSCAFT00040002473.1 UniProtKB/TrEMBL
  ENSCAFT00845003711.1 UniProtKB/TrEMBL
  ENSCAFT00845003736.1 UniProtKB/TrEMBL
  ENSCAFT00845003771 ENTREZGENE
  ENSCAFT00845003771.1 UniProtKB/TrEMBL
  ENSCAFT00845003780 ENTREZGENE
  ENSCAFT00845003780.1 UniProtKB/TrEMBL
Gene3D-CATH 3.20.20.120 UniProtKB/TrEMBL
  3.30.390.10 UniProtKB/TrEMBL
InterPro Enolase-like_C_sf UniProtKB/TrEMBL
  Enolase-like_N UniProtKB/TrEMBL
  Enolase_C-like UniProtKB/TrEMBL
  L-fuconate_dehydratase UniProtKB/TrEMBL
  Mandel_Rmase/mucon_lact_enz_CS UniProtKB/TrEMBL
  Mandelate_racemase_C UniProtKB/TrEMBL
  Mandelate_racemase_N_dom UniProtKB/TrEMBL
  RHMD-like UniProtKB/TrEMBL
NCBI Gene ENOSF1 ENTREZGENE
PANTHER ENOLASE SUPERFAMILY, MANDELATE RACEMASE UniProtKB/TrEMBL
  MITOCHONDRIAL ENOLASE SUPERFAMILY MEMBER 1 UniProtKB/TrEMBL
Pfam MR_MLE_C UniProtKB/TrEMBL
  MR_MLE_N UniProtKB/TrEMBL
PROSITE MR_MLE_2 UniProtKB/TrEMBL
SMART MR_MLE UniProtKB/TrEMBL
Superfamily-SCOP SSF51604 UniProtKB/TrEMBL
  SSF54826 UniProtKB/TrEMBL
UniProt A0A8C0KZT4 ENTREZGENE
  A0A8C0PQK6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0PXU7_CANLF UniProtKB/TrEMBL
  A0A8C0Q1E6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0RKZ7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MHZ7_CANLF UniProtKB/TrEMBL
  A0A8I3MKD4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3N119_CANLF UniProtKB/TrEMBL
  A0A8I3RS04 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0NJK4 ENTREZGENE
  A0A8P0T7U2 ENTREZGENE
UniProt Secondary A0A8P0NJK4 UniProtKB/TrEMBL
  A0A8P0T7U2 UniProtKB/TrEMBL
VGNC ID VGNC:40370 ENTREZGENE