ODC1 (ornithine decarboxylase 1) - Rat Genome Database
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Gene: ODC1 (ornithine decarboxylase 1) Canis lupus familiaris
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Symbol: ODC1
Name: ornithine decarboxylase 1
RGD ID: 12226081
Description: ENCODES a protein that exhibits protein homodimerization activity (inferred); INVOLVED IN polyamine metabolic process (ortholog); putrescine biosynthetic process (ortholog); PARTICIPATES IN polyamine metabolic pathway; putrescine metabolic pathway; spermidine metabolic pathway; ASSOCIATED WITH Colonic Neoplasms (ortholog); colorectal adenoma (ortholog); Colorectal Neoplasms (ortholog); FOUND IN perinuclear region of cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: ornithine decarboxylase
Orthologs:
Homo sapiens (human) : ODC1 (ornithine decarboxylase 1)  HGNC  Alliance
Mus musculus (house mouse) : Odc1 (ornithine decarboxylase, structural 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Odc1 (ornithine decarboxylase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Odc1 (ornithine decarboxylase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ODC1 (ornithine decarboxylase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Odc1 (ornithine decarboxylase 1)
Sus scrofa (pig) : ODC1 (ornithine decarboxylase 1)
Chlorocebus sabaeus (African green monkey) : ODC1 (ornithine decarboxylase 1)
Heterocephalus glaber (naked mole-rat) : Odc1 (ornithine decarboxylase 1)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl177,369,232 - 7,376,975 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1177,368,699 - 7,376,970 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
ODC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl177,369,232 - 7,376,975 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1177,368,699 - 7,376,970 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
ODC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl210,439,968 - 10,448,327 (-)EnsemblGRCh38hg38GRCh38
GRCh38210,439,968 - 10,448,327 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37210,580,507 - 10,588,680 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36210,497,959 - 10,505,904 (-)NCBINCBI36hg18NCBI36
Build 34210,531,105 - 10,539,051NCBI
Celera210,496,293 - 10,504,232 (-)NCBI
Cytogenetic Map2p25.1NCBI
HuRef210,432,740 - 10,440,685 (-)NCBIHuRef
CHM1_1210,509,892 - 10,518,046 (-)NCBICHM1_1
Odc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391217,594,809 - 17,601,503 (+)NCBI
GRCm381217,544,808 - 17,551,502 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1217,544,794 - 17,551,505 (+)EnsemblGRCm38mm10GRCm38
MGSCv371217,551,679 - 17,558,308 (+)NCBIGRCm37mm9NCBIm37
MGSCv361217,570,570 - 17,576,557 (+)NCBImm8
Celera1217,867,446 - 17,874,062 (+)NCBICelera
Cytogenetic Map12A1.1- A1.2NCBI
cM Map128.11NCBI
Odc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0642,852,529 - 42,859,142 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl642,852,683 - 42,859,927 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0652,565,188 - 52,571,773 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4641,309,211 - 41,315,796 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1641,312,265 - 41,318,665 (+)NCBI
Celera639,628,825 - 39,635,308 (+)NCBICelera
Cytogenetic Map6q16NCBI
Odc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554875,603,722 - 5,608,386 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554875,603,722 - 5,608,386 (-)NCBIChiLan1.0ChiLan1.0
ODC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12A10,598,125 - 10,607,152 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A10,598,125 - 10,607,152 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02A10,443,308 - 10,451,412 (-)NCBIMhudiblu_PPA_v0panPan3
Odc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365326,581,717 - 6,587,116 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ODC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3126,078,418 - 126,132,577 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13126,087,013 - 126,095,644 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
ODC1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11497,173,338 - 97,182,253 (+)NCBI
Odc1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248654,851,565 - 4,858,868 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 5 22 6 6 6 6 3 12 8 10 6
Low 3
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_851618 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX03010713 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000036614   ⟹   ENSCAFP00000032017
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl177,369,232 - 7,376,975 (-)Ensembl
RefSeq Acc Id: XM_851618   ⟹   XP_856711
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1177,368,699 - 7,376,970 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_856711 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_856711   ⟸   XM_851618
- UniProtKB: E2R8D9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000032017   ⟸   ENSCAFT00000036614
Protein Domains
Orn_Arg_deC_N   Orn_DAP_Arg_deC

Promoters
RGD ID:13686161
Promoter ID:EPDNEW_C4229
Type:single initiation site
Name:ODC1_1
Description:ornithine decarboxylase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1177,377,010 - 7,377,070EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000003415 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00000032017 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000036614 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 2.40.37.10 UniProtKB/TrEMBL
  3.20.20.10 UniProtKB/TrEMBL
InterPro Ala_racemase/Decarboxylase_C UniProtKB/TrEMBL
  De-COase2_C UniProtKB/TrEMBL
  De-COase2_CS UniProtKB/TrEMBL
  De-COase2_N UniProtKB/TrEMBL
  De-COase2_pyr-phos_BS UniProtKB/TrEMBL
  Orn/DAP/Arg_de-COase UniProtKB/TrEMBL
  Orn_de-COase UniProtKB/TrEMBL
  PLP-binding_barrel UniProtKB/TrEMBL
NCBI Gene ODC1 ENTREZGENE
PANTHER PTHR11482 UniProtKB/TrEMBL
Pfam Orn_Arg_deC_N UniProtKB/TrEMBL
  Orn_DAP_Arg_deC UniProtKB/TrEMBL
PRINTS ODADCRBXLASE UniProtKB/TrEMBL
  ORNDCRBXLASE UniProtKB/TrEMBL
PROSITE ODR_DC_2_1 UniProtKB/TrEMBL
  ODR_DC_2_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF50621 UniProtKB/TrEMBL
  SSF51419 UniProtKB/TrEMBL
UniProt E2R8D9 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:44097 ENTREZGENE