SLC27A6 (solute carrier family 27 member 6) - Rat Genome Database

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Gene: SLC27A6 (solute carrier family 27 member 6) Canis lupus familiaris
Analyze
Symbol: SLC27A6
Name: solute carrier family 27 member 6
RGD ID: 12220719
Description: ENCODES a protein that exhibits long-chain fatty acid transmembrane transporter activity (inferred); long-chain fatty acid-CoA ligase activity (inferred); nucleotide binding (inferred); INVOLVED IN lipid metabolic process (inferred); ASSOCIATED WITH atrial fibrillation (ortholog); familial adenomatous polyposis 1 (ortholog); genetic disease (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: long-chain fatty acid transport protein 6
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11117,899,270 - 17,968,940 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1117,899,556 - 17,968,910 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1116,695,506 - 16,764,832 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01118,648,822 - 18,718,353 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1118,648,148 - 18,720,578 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11117,368,838 - 17,438,043 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01117,207,260 - 17,276,725 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01117,820,174 - 17,889,446 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
SLC27A6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11117,899,270 - 17,968,940 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1117,899,556 - 17,968,910 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1116,695,506 - 16,764,832 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01118,648,822 - 18,718,353 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1118,648,148 - 18,720,578 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11117,368,838 - 17,438,043 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01117,207,260 - 17,276,725 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01117,820,174 - 17,889,446 (+)NCBIUU_Cfam_GSD_1.0
SLC27A6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385128,965,488 - 129,033,635 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5128,538,013 - 129,033,642 (+)EnsemblGRCh38hg38GRCh38
GRCh375128,301,181 - 128,369,328 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365128,329,109 - 128,397,234 (+)NCBINCBI36Build 36hg18NCBI36
Build 345128,329,108 - 128,397,223NCBI
Celera5124,432,488 - 124,500,533 (+)NCBICelera
Cytogenetic Map5q23.3NCBI
HuRef5123,491,347 - 123,560,656 (+)NCBIHuRef
CHM1_15127,734,035 - 127,802,014 (+)NCBICHM1_1
T2T-CHM13v2.05129,484,343 - 129,552,406 (+)NCBIT2T-CHM13v2.0
Slc27a6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391858,689,312 - 58,745,941 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1858,689,329 - 58,745,845 (+)EnsemblGRCm39 Ensembl
GRCm381858,556,240 - 58,612,869 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1858,556,257 - 58,612,773 (+)EnsemblGRCm38mm10GRCm38
MGSCv371858,715,894 - 58,772,523 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361858,681,609 - 58,738,238 (+)NCBIMGSCv36mm8
Celera1859,859,537 - 59,916,121 (+)NCBICelera
Cytogenetic Map18D3NCBI
cM Map1833.71NCBI
Slc27a6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81854,238,697 - 54,297,595 (+)NCBIGRCr8
mRatBN7.21852,040,241 - 52,099,622 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1852,041,074 - 52,099,414 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1854,065,230 - 54,123,472 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01854,779,791 - 54,838,039 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01852,591,760 - 52,650,092 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01853,609,497 - 53,667,833 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1853,609,214 - 53,667,970 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01852,825,799 - 52,891,779 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41854,351,476 - 54,412,298 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1850,159,252 - 50,211,328 (+)NCBICelera
Cytogenetic Map18q12.1NCBI
Slc27a6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554151,973,308 - 2,041,866 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554151,973,308 - 2,041,800 (+)NCBIChiLan1.0ChiLan1.0
SLC27A6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24124,272,893 - 124,341,933 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15122,412,453 - 122,481,493 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05124,378,721 - 124,447,729 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15130,140,646 - 130,209,798 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5130,140,967 - 130,212,940 (+)Ensemblpanpan1.1panPan2
Slc27a6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213140,578,487 - 140,634,443 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365042,152,394 - 2,208,394 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365042,152,449 - 2,208,295 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC27A6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2131,750,473 - 131,814,410 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12131,749,759 - 131,848,278 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22137,111,909 - 137,175,153 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLC27A6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12331,911,865 - 31,981,217 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2331,913,575 - 31,981,147 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603446,054,655 - 46,117,474 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc27a6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477412,287,918 - 12,344,375 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477412,287,576 - 12,344,604 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SLC27A6
906 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 6 6 6 6 3
Low 4 15 6 5 12 2 9 3
Below cutoff 1 5 1 1 6 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000001116   ⟹   ENSCAFP00000001025
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1117,899,556 - 17,968,910 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845012556   ⟹   ENSCAFP00845009808
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1118,648,148 - 18,720,578 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845012600   ⟹   ENSCAFP00845009835
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1118,648,148 - 18,718,323 (+)Ensembl
RefSeq Acc Id: XM_005626491   ⟹   XP_005626548
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11117,899,270 - 17,968,940 (+)NCBI
Dog10K_Boxer_Tasha1116,695,506 - 16,764,832 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038489989   ⟹   XP_038345917
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11117,368,842 - 17,438,043 (+)NCBI
RefSeq Acc Id: XM_038489990   ⟹   XP_038345918
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11117,368,838 - 17,438,043 (+)NCBI
RefSeq Acc Id: XM_038552059   ⟹   XP_038407987
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01117,820,179 - 17,889,446 (+)NCBI
RefSeq Acc Id: XM_038552060   ⟹   XP_038407988
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01117,820,174 - 17,889,446 (+)NCBI
RefSeq Acc Id: XM_038615923   ⟹   XP_038471851
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01117,207,265 - 17,276,725 (+)NCBI
RefSeq Acc Id: XM_038615924   ⟹   XP_038471852
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01117,207,260 - 17,276,725 (+)NCBI
RefSeq Acc Id: XM_038681417   ⟹   XP_038537345
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01118,648,827 - 18,718,353 (+)NCBI
RefSeq Acc Id: XM_038681418   ⟹   XP_038537346
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01118,648,822 - 18,718,353 (+)NCBI
RefSeq Acc Id: XM_531894   ⟹   XP_531894
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11117,899,275 - 17,968,940 (+)NCBI
Dog10K_Boxer_Tasha1116,695,510 - 16,764,832 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_531894   ⟸   XM_531894
- Peptide Label: isoform X1
- UniProtKB: A0A8C0P495 (UniProtKB/TrEMBL),   A0A8C0KLJ7 (UniProtKB/TrEMBL),   A0A8I3N4Y3 (UniProtKB/TrEMBL),   A0A8I3N4V0 (UniProtKB/TrEMBL),   A0A8P0PFJ6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005626548   ⟸   XM_005626491
- Peptide Label: isoform X2
- UniProtKB: A0A8I3N4V0 (UniProtKB/TrEMBL),   A0A8P0PFJ6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000001025   ⟸   ENSCAFT00000001116
RefSeq Acc Id: XP_038345918   ⟸   XM_038489990
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038345917   ⟸   XM_038489989
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038471852   ⟸   XM_038615924
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038471851   ⟸   XM_038615923
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038537346   ⟸   XM_038681418
- Peptide Label: isoform X2
- UniProtKB: A0A8I3N4V0 (UniProtKB/TrEMBL),   A0A8P0PFJ6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038537345   ⟸   XM_038681417
- Peptide Label: isoform X1
- UniProtKB: A0A8C0P495 (UniProtKB/TrEMBL),   A0A8C0KLJ7 (UniProtKB/TrEMBL),   A0A8I3N4Y3 (UniProtKB/TrEMBL),   A0A8I3N4V0 (UniProtKB/TrEMBL),   A0A8P0PFJ6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038407988   ⟸   XM_038552060
- Peptide Label: isoform X2
- UniProtKB: A0A8I3N4V0 (UniProtKB/TrEMBL),   A0A8P0PFJ6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038407987   ⟸   XM_038552059
- Peptide Label: isoform X1
- UniProtKB: A0A8I3N4V0 (UniProtKB/TrEMBL),   A0A8P0PFJ6 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845009835   ⟸   ENSCAFT00845012600
RefSeq Acc Id: ENSCAFP00845009808   ⟸   ENSCAFT00845012556
Protein Domains
AMP-binding enzyme C-terminal   AMP-dependent synthetase/ligase

Promoters
RGD ID:13685158
Promoter ID:EPDNEW_C3225
Type:initiation region
Name:SLC27A6_1
Description:solute carrier family 27 member 6
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11117,899,086 - 17,899,146EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000000710 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030021608 UniProtKB/TrEMBL
  ENSCAFG00040009393 UniProtKB/TrEMBL
  ENSCAFG00845007075 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000001116.5 UniProtKB/TrEMBL
  ENSCAFT00000101769.1 UniProtKB/TrEMBL
  ENSCAFT00030039703.1 UniProtKB/TrEMBL
  ENSCAFT00040017487.1 UniProtKB/TrEMBL
  ENSCAFT00845012556.1 UniProtKB/TrEMBL
  ENSCAFT00845012600 ENTREZGENE
  ENSCAFT00845012600.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.300.30 UniProtKB/TrEMBL
  3.40.50.12780 UniProtKB/TrEMBL
InterPro AMP-bd_C UniProtKB/TrEMBL
  AMP-bd_C_sf UniProtKB/TrEMBL
  AMP-binding_CS UniProtKB/TrEMBL
  AMP-dep_Synth/Lig UniProtKB/TrEMBL
  ANL_N_sf UniProtKB/TrEMBL
NCBI Gene SLC27A6 ENTREZGENE
PANTHER LONG-CHAIN FATTY ACID TRANSPORT PROTEIN UniProtKB/TrEMBL
  PTHR43107:SF10 UniProtKB/TrEMBL
Pfam AMP-binding UniProtKB/TrEMBL
  AMP-binding_C UniProtKB/TrEMBL
PROSITE AMP_BINDING UniProtKB/TrEMBL
Superfamily-SCOP Acetyl-CoA synthetase-like UniProtKB/TrEMBL
UniProt A0A8C0KLJ7 ENTREZGENE
  A0A8C0P495 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3N4V0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3N4Y3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0PFJ6 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:46333 ENTREZGENE