ASCL5 (achaete-scute family bHLH transcription factor 5) - Rat Genome Database

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Gene: ASCL5 (achaete-scute family bHLH transcription factor 5) Canis lupus familiaris
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Symbol: ASCL5
Name: achaete-scute family bHLH transcription factor 5
RGD ID: 12220072
Description: ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); DNA-binding transcription factor binding (inferred); INVOLVED IN ameloblast differentiation (inferred); amelogenesis (inferred); developmental process (inferred); ASSOCIATED WITH familial adult myoclonic epilepsy 5 (ortholog); gastrointestinal stromal tumor (ortholog); Hypokalemic Periodic Paralysis, Type 1 (ortholog); FOUND IN chromatin (inferred); RNA polymerase II transcription regulator complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: achaete-scute complex homolog 5; achaete-scute homolog 5; ASH3B
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.172,106,480 - 2,107,046 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha71,790,943 - 1,791,497 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.071,753,170 - 1,753,742 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl71,753,170 - 1,753,742 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.171,736,540 - 1,737,106 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.071,839,210 - 1,839,771 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.071,868,992 - 1,869,558 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:25403511   PMID:30032202  


Genomics

Comparative Map Data
ASCL5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.172,106,480 - 2,107,046 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha71,790,943 - 1,791,497 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.071,753,170 - 1,753,742 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl71,753,170 - 1,753,742 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.171,736,540 - 1,737,106 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.071,839,210 - 1,839,771 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.071,868,992 - 1,869,558 (+)NCBIUU_Cfam_GSD_1.0
ASCL5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381201,113,943 - 201,127,184 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1201,113,943 - 201,127,184 (-)EnsemblGRCh38hg38GRCh38
GRCh371201,083,071 - 201,096,312 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361199,350,256 - 199,364,960 (-)NCBINCBI36Build 36hg18NCBI36
Celera1174,207,616 - 174,223,353 (-)NCBICelera
Cytogenetic Map1q32.1NCBI
HuRef1172,249,704 - 172,251,123 (-)NCBIHuRef
CHM1_11202,505,741 - 202,507,160 (-)NCBICHM1_1
T2T-CHM13v2.01200,370,927 - 200,384,168 (-)NCBIT2T-CHM13v2.0
Ascl5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391135,978,321 - 135,979,810 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1135,978,542 - 135,979,108 (+)EnsemblGRCm39 Ensembl
GRCm381136,050,804 - 136,051,370 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1136,050,804 - 136,051,370 (+)EnsemblGRCm38mm10GRCm38
MGSCv371137,947,381 - 137,947,947 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361137,867,215 - 137,867,781 (+)NCBIMGSCv36mm8
MGSCv361136,920,172 - 136,920,738 (+)NCBIMGSCv36mm8
Celera1138,685,121 - 138,685,687 (+)NCBICelera
Cytogenetic Map1E4NCBI
cM Map159.54NCBI
Ascl5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81350,043,520 - 50,044,988 (+)NCBIGRCr8
mRatBN7.21347,491,799 - 47,493,269 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1347,492,026 - 47,492,592 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1350,099,916 - 50,101,384 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01351,387,999 - 51,389,467 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01348,651,190 - 48,652,646 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01352,887,055 - 52,888,603 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1352,887,649 - 52,888,215 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01357,942,911 - 57,944,532 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41349,093,924 - 49,094,490 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1347,807,250 - 47,808,798 (+)NCBICelera
Cytogenetic Map13q13NCBI
Ascl5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540637,264,753 - 37,265,337 (-)NCBIChiLan1.0ChiLan1.0
ASCL5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2148,257,361 - 48,266,697 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1148,220,963 - 48,230,275 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01176,713,717 - 176,726,991 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11181,016,950 - 181,017,603 (-)NCBIpanpan1.1PanPan1.1panPan2
Ascl5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934474,031,958 - 74,033,706 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365673,267,224 - 3,267,829 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365673,267,224 - 3,267,841 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ASCL5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1023,569,391 - 23,569,927 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11023,568,676 - 23,569,987 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21028,000,895 - 28,001,431 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ASCL5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12528,274,562 - 28,287,783 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2528,286,370 - 28,286,987 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605529,084,991 - 29,087,269 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ascl5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248079,558,031 - 9,558,624 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248079,558,031 - 9,559,263 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ASCL5
3 total Variants

Expression


Sequence


RefSeq Acc Id: ENSCAFT00845033578   ⟹   ENSCAFP00845026286
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl71,753,170 - 1,753,742 (+)Ensembl
RefSeq Acc Id: XM_038480484   ⟹   XP_038336412
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.171,736,540 - 1,737,106 (+)NCBI
RefSeq Acc Id: XM_038541736   ⟹   XP_038397664
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.071,868,992 - 1,869,558 (+)NCBI
RefSeq Acc Id: XM_038560141   ⟹   XP_038416069
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha71,790,943 - 1,791,497 (+)NCBI
RefSeq Acc Id: XM_038605860   ⟹   XP_038461788
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.071,839,210 - 1,839,771 (+)NCBI
RefSeq Acc Id: XM_038670574   ⟹   XP_038526502
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.071,753,170 - 1,753,742 (+)NCBI
RefSeq Acc Id: XP_038336412   ⟸   XM_038480484
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038461788   ⟸   XM_038605860
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038526502   ⟸   XM_038670574
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038416069   ⟸   XM_038560141
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038397664   ⟸   XM_038541736
- Peptide Label: isoform X4
RefSeq Acc Id: ENSCAFP00845026286   ⟸   ENSCAFT00845033578
Protein Domains
bHLH


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000053045 UniProtKB/TrEMBL
  ENSCAFG00845019036 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000107939.1 UniProtKB/TrEMBL
  ENSCAFT00845033578.1 UniProtKB/TrEMBL
Gene3D-CATH 4.10.280.10 UniProtKB/TrEMBL
InterPro bHLH_dom UniProtKB/TrEMBL
  HLH_DNA-bd_sf UniProtKB/TrEMBL
NCBI Gene ASCL5 ENTREZGENE
PANTHER ACHAETE-SCUTE FAMILY BHLH TRANSCRIPTION FACTOR 5 UniProtKB/TrEMBL
  BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST UniProtKB/TrEMBL
Pfam HLH UniProtKB/TrEMBL
PROSITE BHLH UniProtKB/TrEMBL
SMART HLH UniProtKB/TrEMBL
Superfamily-SCOP SSF47459 UniProtKB/TrEMBL
UniProt A0A8I3S0U0_CANLF UniProtKB/TrEMBL
  A0A8P0TR72_CANLF UniProtKB/TrEMBL