LOC609540 (DDB1- and CUL4-associated factor 12-like protein 2) - Rat Genome Database

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Gene: LOC609540 (DDB1- and CUL4-associated factor 12-like protein 2) Canis lupus familiaris
Analyze
Symbol: LOC609540
Name: DDB1- and CUL4-associated factor 12-like protein 2
RGD ID: 12215273
Description: ASSOCIATED WITH autistic disorder (ortholog); genetic disease (ortholog); syndromic X-linked intellectual disability Lubs type (ortholog); FOUND IN Cul4-RING E3 ubiquitin ligase complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_TashaX83,835,516 - 83,837,103 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X99,542,727 - 99,544,556 (-)NCBIROS_Cfam_1.0
UNSW_CanFamBas_1.0X98,794,007 - 98,795,577 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X98,521,261 - 98,522,828 (-)NCBIUU_Cfam_GSD_1.0


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
LOC609540
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_TashaX83,835,516 - 83,837,103 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X99,542,727 - 99,544,556 (-)NCBIROS_Cfam_1.0
UNSW_CanFamBas_1.0X98,794,007 - 98,795,577 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X98,521,261 - 98,522,828 (-)NCBIUU_Cfam_GSD_1.0
DCAF12L2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X126,163,499 - 126,166,289 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX126,163,499 - 126,166,289 (-)EnsemblGRCh38hg38GRCh38
GRCh37X125,297,482 - 125,300,272 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X125,126,195 - 125,127,615 (-)NCBINCBI36Build 36hg18NCBI36
CeleraX125,683,150 - 125,685,748 (-)NCBICelera
Cytogenetic MapXq25NCBI
HuRefX114,677,469 - 114,680,067 (-)NCBIHuRef
CHM1_1X125,208,368 - 125,210,966 (-)NCBICHM1_1
T2T-CHM13v2.0X124,476,206 - 124,478,996 (-)NCBIT2T-CHM13v2.0
Dcaf12l2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X43,454,334 - 43,457,214 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX43,454,335 - 43,457,219 (-)EnsemblGRCm39 Ensembl
GRCm38X44,365,457 - 44,368,337 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX44,365,458 - 44,368,342 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X41,718,634 - 41,721,514 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X40,610,085 - 40,612,969 (-)NCBIMGSCv36mm8
CeleraX31,900,316 - 31,903,196 (-)NCBICelera
Cytogenetic MapXA4NCBI
cM MapX23.85NCBI
Dcaf12l2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X128,167,040 - 128,169,829 (-)NCBIGRCr8
mRatBN7.2X123,293,761 - 123,296,550 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX123,294,744 - 123,296,156 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0X130,823,651 - 130,825,369 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX130,823,866 - 130,825,305 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X130,906,292 - 130,907,919 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X598,952 - 602,981 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX122,356,923 - 122,358,641 (-)NCBICelera
Cytogenetic MapXq35NCBI
Dcaf12l2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554738,744,885 - 8,746,279 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554738,744,863 - 8,746,589 (+)NCBIChiLan1.0ChiLan1.0
DCAF12L2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X125,637,005 - 125,639,898 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X125,640,617 - 125,643,504 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X115,346,153 - 115,349,054 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X125,525,080 - 125,527,429 (-)NCBIpanpan1.1PanPan1.1panPan2
LOC100521308
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX103,325,989 - 103,327,383 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X103,322,468 - 103,327,458 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X118,320,653 - 118,323,147 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103247388
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366606538,870,103 - 38,872,678 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium
Low 1 6
Below cutoff 3 5 15 2 3 1 6 8 10 6

Sequence


Reference Sequences
RefSeq Acc Id: XM_038449058   ⟹   XP_038304986
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0X99,542,727 - 99,544,556 (-)NCBI
RefSeq Acc Id: XM_038586600   ⟹   XP_038442528
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0X98,521,261 - 98,522,828 (-)NCBI
RefSeq Acc Id: XM_038651018   ⟹   XP_038506946
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0X98,794,007 - 98,795,577 (-)NCBI
RefSeq Acc Id: XM_846810   ⟹   XP_851903
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_TashaX83,835,516 - 83,837,103 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_038506946   ⟸   XM_038651018
RefSeq Acc Id: XP_038304986   ⟸   XM_038449058
- UniProtKB: A0A8C0RKB0 (UniProtKB/TrEMBL),   A0A8I3Q873 (UniProtKB/TrEMBL),   A0A8C0T524 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_851903   ⟸   XM_846810
- UniProtKB: A0A8C0JN85 (UniProtKB/TrEMBL),   A0A8P0SQX3 (UniProtKB/TrEMBL),   A0A8C0T524 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_038442528   ⟸   XM_038586600
- UniProtKB: A0A8C0RKB0 (UniProtKB/TrEMBL),   A0A8C0T524 (UniProtKB/TrEMBL),   A0A8I3Q873 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000018646 UniProtKB/TrEMBL
  ENSCAFG00000025552 UniProtKB/TrEMBL
  ENSCAFG00030014682 UniProtKB/TrEMBL
  ENSCAFG00040018927 UniProtKB/TrEMBL
  ENSCAFG00845030952 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000029601.5 UniProtKB/TrEMBL
  ENSCAFT00000039768.3 UniProtKB/TrEMBL
  ENSCAFT00030027093.1 UniProtKB/TrEMBL
  ENSCAFT00040034975.1 UniProtKB/TrEMBL
  ENSCAFT00845055010 ENTREZGENE
  ENSCAFT00845055010.1 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
InterPro WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
NCBI Gene LOC609540 ENTREZGENE
PANTHER DDB1- AND CUL4-ASSOCIATED FACTOR 12-LIKE PROTEIN 2 UniProtKB/TrEMBL
  DDB1- AND CUL4-ASSOCIATED FACTOR 12-RELATED UniProtKB/TrEMBL
Pfam WD40 UniProtKB/TrEMBL
PROSITE WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
SMART WD40 UniProtKB/TrEMBL
Superfamily-SCOP SSF50978 UniProtKB/TrEMBL
UniProt A0A8C0JN85 ENTREZGENE
  A0A8C0RKB0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0T524 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3Q873 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0SQX3 ENTREZGENE, UniProtKB/TrEMBL