MRPL4 (mitochondrial ribosomal protein L4) - Rat Genome Database

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Gene: MRPL4 (mitochondrial ribosomal protein L4) Canis lupus familiaris
Analyze
Symbol: MRPL4
Name: mitochondrial ribosomal protein L4
RGD ID: 12209954
Description: ENCODES a protein that exhibits structural constituent of ribosome (inferred); INVOLVED IN translation (inferred); ASSOCIATED WITH genetic disease (ortholog); FOUND IN mitochondrial large ribosomal subunit (inferred); mitochondrion (inferred); ribonucleoprotein complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 39S ribosomal protein L4, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12050,836,263 - 50,843,311 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2050,837,541 - 50,843,257 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2050,705,811 - 50,712,846 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02051,357,681 - 51,364,718 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2051,357,684 - 51,375,019 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12050,563,815 - 50,570,847 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02050,993,011 - 51,000,051 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02051,233,746 - 51,240,779 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
translation  (IEA)

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
MRPL4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12050,836,263 - 50,843,311 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2050,837,541 - 50,843,257 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2050,705,811 - 50,712,846 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02051,357,681 - 51,364,718 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2051,357,684 - 51,375,019 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12050,563,815 - 50,570,847 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02050,993,011 - 51,000,051 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02051,233,746 - 51,240,779 (-)NCBIUU_Cfam_GSD_1.0
MRPL4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381910,251,951 - 10,260,055 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1910,251,901 - 10,260,055 (+)EnsemblGRCh38hg38GRCh38
GRCh371910,362,627 - 10,370,731 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361910,223,640 - 10,231,736 (+)NCBINCBI36Build 36hg18NCBI36
Build 341910,223,639 - 10,231,736NCBI
Celera1910,258,038 - 10,266,134 (+)NCBICelera
Cytogenetic Map19p13.2NCBI
HuRef199,942,881 - 9,950,978 (+)NCBIHuRef
CHM1_11910,362,919 - 10,371,000 (+)NCBICHM1_1
T2T-CHM13v2.01910,378,061 - 10,386,165 (+)NCBIT2T-CHM13v2.0
Mrpl4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39920,907,040 - 20,920,135 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl920,914,034 - 20,920,135 (+)EnsemblGRCm39 Ensembl
GRCm38921,001,252 - 21,008,839 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl921,002,738 - 21,008,839 (+)EnsemblGRCm38mm10GRCm38
MGSCv37920,807,181 - 20,813,283 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36920,753,388 - 20,774,632 (+)NCBIMGSCv36mm8
Celera918,271,419 - 18,277,521 (+)NCBICelera
Cytogenetic Map9A3NCBI
cM Map97.69NCBI
Mrpl4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8827,815,771 - 27,821,786 (+)NCBIGRCr8
mRatBN7.2819,539,593 - 19,545,608 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl819,539,593 - 19,545,608 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx823,559,026 - 23,565,036 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0821,856,870 - 21,862,880 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0819,769,264 - 19,775,279 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0822,021,213 - 22,027,228 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl822,021,213 - 22,027,228 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0822,078,081 - 22,084,096 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4820,026,103 - 20,032,118 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1820,015,512 - 20,031,898 (+)NCBI
Celera820,934,016 - 20,940,031 (+)NCBICelera
Cytogenetic Map8q13NCBI
Mrpl4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554951,550,798 - 1,556,807 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554951,551,181 - 1,555,976 (+)NCBIChiLan1.0ChiLan1.0
MRPL4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22015,168,857 - 15,177,001 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11914,167,004 - 14,175,599 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0199,802,353 - 9,810,433 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11910,465,462 - 10,473,548 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1910,465,461 - 10,473,548 (+)Ensemblpanpan1.1panPan2
Mrpl4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118209,747,042 - 209,750,417 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936659604,117 - 607,666 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936659604,310 - 607,664 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MRPL4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl269,063,674 - 69,082,688 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1269,063,679 - 69,082,692 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2269,401,482 - 69,417,255 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MRPL4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.169,304,882 - 9,314,215 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl69,304,913 - 9,314,220 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607410,730,275 - 10,738,417 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mrpl4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248282,419,612 - 2,425,326 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248282,419,412 - 2,424,610 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in MRPL4
62 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 5 22 6 6 6 6 6 12 8 10 6
Low
Below cutoff

Sequence


RefSeq Acc Id: ENSCAFT00000028364   ⟹   ENSCAFP00000026378
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2050,837,541 - 50,843,257 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000075493   ⟹   ENSCAFP00000061539
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2050,838,170 - 50,843,137 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845049601   ⟹   ENSCAFP00845038907
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2051,357,684 - 51,364,556 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845049665   ⟹   ENSCAFP00845038955
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2051,357,689 - 51,375,019 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845049721   ⟹   ENSCAFP00845038994
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2051,359,375 - 51,364,649 (-)Ensembl
RefSeq Acc Id: XM_038428669   ⟹   XP_038284597
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02051,357,681 - 51,364,718 (-)NCBI
RefSeq Acc Id: XM_038504312   ⟹   XP_038360240
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12050,563,815 - 50,570,847 (-)NCBI
RefSeq Acc Id: XM_038567344   ⟹   XP_038423272
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02051,233,746 - 51,240,779 (-)NCBI
RefSeq Acc Id: XM_038631492   ⟹   XP_038487420
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02050,993,011 - 51,000,051 (-)NCBI
RefSeq Acc Id: XM_848920   ⟹   XP_854013
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12050,836,263 - 50,843,311 (-)NCBI
Dog10K_Boxer_Tasha2050,705,811 - 50,712,846 (-)NCBI
Sequence:
RefSeq Acc Id: XP_854013   ⟸   XM_848920
- UniProtKB: A0A8I3QHV4 (UniProtKB/TrEMBL),   A0A8P0SM19 (UniProtKB/TrEMBL),   A0A8C0TFP8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000026378   ⟸   ENSCAFT00000028364
RefSeq Acc Id: ENSCAFP00000061539   ⟸   ENSCAFT00000075493
RefSeq Acc Id: XP_038360240   ⟸   XM_038504312
RefSeq Acc Id: XP_038487420   ⟸   XM_038631492
RefSeq Acc Id: XP_038284597   ⟸   XM_038428669
- UniProtKB: A0A8I3QHV4 (UniProtKB/TrEMBL),   A0A8P0SM19 (UniProtKB/TrEMBL),   A0A8C0TFP8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038423272   ⟸   XM_038567344
- UniProtKB: A0A8C0TFP8 (UniProtKB/TrEMBL),   A0A8I3QHV4 (UniProtKB/TrEMBL),   A0A8P0SM19 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845038907   ⟸   ENSCAFT00845049601
RefSeq Acc Id: ENSCAFP00845038955   ⟸   ENSCAFT00845049665
RefSeq Acc Id: ENSCAFP00845038994   ⟸   ENSCAFT00845049721

Promoters
RGD ID:13687042
Promoter ID:EPDNEW_C5110
Type:initiation region
Name:MRPL4_1
Description:mitochondrial ribosomal protein L4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12050,843,266 - 50,843,326EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000017881 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00040021493 UniProtKB/TrEMBL
  ENSCAFG00845028082 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000028364.5 UniProtKB/TrEMBL
  ENSCAFT00040039938.1 UniProtKB/TrEMBL
  ENSCAFT00845049601.1 UniProtKB/TrEMBL
  ENSCAFT00845049665 ENTREZGENE
  ENSCAFT00845049665.1 UniProtKB/TrEMBL
  ENSCAFT00845049721.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.1370.10 UniProtKB/TrEMBL
InterPro Ribosomal_L4/L1e UniProtKB/TrEMBL
  Ribosomal_L4_dom_sf UniProtKB/TrEMBL
  Ribosomal_uL4/L1e UniProtKB/TrEMBL
KEGG Report cfa:611273 UniProtKB/TrEMBL
NCBI Gene MRPL4 ENTREZGENE
PANTHER 39S RIBOSOMAL PROTEIN L4, MITOCHONDRIAL UniProtKB/TrEMBL
  PTHR10746 UniProtKB/TrEMBL
Pfam Ribosomal_L4 UniProtKB/TrEMBL
Superfamily-SCOP SSF52166 UniProtKB/TrEMBL
UniProt A0A8C0TFP8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3PUZ7_CANLF UniProtKB/TrEMBL
  A0A8I3QGL7_CANLF UniProtKB/TrEMBL
  A0A8I3QHV4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0SM19 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:43397 ENTREZGENE