NDC80 (NDC80 kinetochore complex component)

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Gene: NDC80 (NDC80 kinetochore complex component) Canis lupus familiaris

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Symbol:

NDC80

Name:

NDC80 kinetochore complex component

RGD ID:

12207036

Description:

ENCODES a protein that exhibits cyclin binding (ortholog); INVOLVED IN centrosome duplication (ortholog); G2/MI transition of meiotic cell cycle (ortholog); kinetochore organization (ortholog); ASSOCIATED WITH colorectal cancer (ortholog); hepatocellular carcinoma (ortholog); intellectual disability (ortholog); FOUND IN cytoplasm (ortholog); kinetochore (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

kinetochore protein NDC80 homolog; NDC80 homolog, kinetochore complex component; NDC80 kinetochore complex component homolog; NDC80, kinetochore complex component

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	69,268,218 - 69,317,126 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	7	69,268,242 - 69,317,072 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	68,723,201 - 68,772,189 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	69,329,940 - 69,378,870 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	7	69,329,990 - 69,378,835 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	7	69,012,589 - 69,061,471 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	69,032,710 - 69,081,627 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	69,329,927 - 69,378,829 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

colorectal cancer (ISO)

hepatocellular carcinoma (ISO)

intellectual disability (ISO)

lung non-small cell carcinoma (ISO)

Neoplasm Metastasis (ISO)

stomach cancer (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

attachment of mitotic spindle microtubules to kinetochore (IEA)

attachment of spindle microtubules to kinetochore (IEA)

cell division (IEA)

centrosome duplication (IEA,ISO)

chromosome segregation (IEA)

establishment of mitotic spindle orientation (IEA)

G2/MI transition of meiotic cell cycle (ISO)

kinetochore organization (ISO)

metaphase chromosome alignment (IEA,ISO)

mitotic spindle organization (IEA)

positive regulation of mitotic cell cycle spindle assembly checkpoint (IEA)

regulation of protein stability (ISO)

skeletal muscle satellite cell proliferation (ISO)

spindle assembly involved in female meiosis I (ISO)

Cellular Component

centrosome (IEA)

chromosome (IEA)

chromosome, centromeric region (IEA)

cytoplasm (ISO)

kinetochore (IEA,ISO)

Ndc80 complex (IEA)

nucleoplasm (IEA)

nucleus (IEA)

outer kinetochore (IEA)

Molecular Function

cyclin binding (ISO)

identical protein binding (IEA)

kinetochore adaptor activity (IEA)

microtubule binding (IEA)

protein binding (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

NDC80
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	69,268,218 - 69,317,126 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	7	69,268,242 - 69,317,072 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	68,723,201 - 68,772,189 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	69,329,940 - 69,378,870 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	7	69,329,990 - 69,378,835 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	7	69,012,589 - 69,061,471 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	69,032,710 - 69,081,627 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	69,329,927 - 69,378,829 (+)	NCBI		UU_Cfam_GSD_1.0

NDC80
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	18	2,571,557 - 2,616,635 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	18	2,571,557 - 2,616,635 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	18	2,571,556 - 2,616,634 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	18	2,561,605 - 2,606,629 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	18	2,561,604 - 2,606,626	NCBI
Celera	18	2,446,814 - 2,491,757 (+)	NCBI		Celera
Cytogenetic Map	18	p11.32	NCBI
HuRef	18	2,532,999 - 2,577,942 (+)	NCBI		HuRef
CHM1_1	18	2,570,883 - 2,615,800 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	18	2,727,304 - 2,772,223 (+)	NCBI		T2T-CHM13v2.0

Ndc80
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	71,803,095 - 71,833,852 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	71,803,095 - 71,833,852 (-)	Ensembl		GRCm39 Ensembl
GRCm38	17	71,496,100 - 71,526,857 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	71,496,100 - 71,526,857 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	71,845,440 - 71,876,197 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	17	71,400,962 - 71,431,714 (-)	NCBI		MGSCv36	mm8
Celera	17	75,767,449 - 75,800,160 (-)	NCBI		Celera
Cytogenetic Map	17	E1.3	NCBI
cM Map	17	41.87	NCBI

Ndc80
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	118,853,806 - 118,887,582 (-)	NCBI		GRCr8
mRatBN7.2	9	111,407,191 - 111,440,921 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	111,407,191 - 111,440,924 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	119,805,258 - 119,842,593 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	124,934,621 - 124,971,844 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	123,271,148 - 123,308,405 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	119,837,857 - 119,871,435 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	119,839,016 - 119,871,382 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	119,291,271 - 119,324,839 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	110,702,935 - 110,718,894 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	110,912,517 - 110,945,708 (-)	NCBI
Celera	9	108,536,354 - 108,552,152 (-)	NCBI		Celera
Cytogenetic Map	9	q38	NCBI

Ndc80
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955402	7,691,937 - 7,729,690 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955402	7,692,009 - 7,728,876 (-)	NCBI	ChiLan1.0	ChiLan1.0

NDC80
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	17	35,829,184 - 35,874,768 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	18	21,521,776 - 21,567,360 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	18	11,666,099 - 11,711,456 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	18	13,972,637 - 14,018,261 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	18	13,972,637 - 14,018,261 (-)	Ensembl	panpan1.1		panPan2

Ndc80
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404944	65,630,900 - 65,669,747 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936672	1,872,193 - 1,909,675 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936672	1,872,205 - 1,910,956 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NDC80
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	103,999,034 - 104,055,760 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	104,000,794 - 104,055,785 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	97,024,076 - 97,061,162 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NDC80
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	18	61,835,027 - 61,882,660 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	18	61,835,064 - 61,881,627 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666050	36,694,925 - 36,740,902 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ndc80
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624770	12,939,763 - 12,974,162 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624770	12,937,887 - 12,974,352 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in NDC80
747 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	reproductive system	respiratory system
6	5	5	23	22	16	6	6	6	6	32	21	12	14	10

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_022421541	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038482269	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038482270	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038482271	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038543704	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038543705	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038543706	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038576700	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038607830	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038607831	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038607832	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038672513	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038672514	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038672515	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_537313	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000084	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000093	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000022	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00000029233 ⟹ ENSCAFP00000027183

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	7	69,268,242 - 69,317,072 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00000065585 ⟹ ENSCAFP00000052590

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	7	69,268,242 - 69,312,293 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845004368 ⟹ ENSCAFP00845003490

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	7	69,329,990 - 69,378,835 (+)	Ensembl

RefSeq Acc Id:

XM_022421541 ⟹ XP_022277249

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	7	69,268,218 - 69,317,126 (+)	NCBI
Dog10K_Boxer_Tasha	7	68,723,201 - 68,772,189 (+)	NCBI

Sequence:

show sequence

TTTCAAATTCGAACTGCGCCGGCGGGTGCGGGGAGGAGTTGGGTGTTTTGGCGGCTGTCGTCCT
GCCTCGCAAATAGTTGCGCGGATTACGGATTCGGCCCTTGGATTGTATCACGAAACTGGAAGAA
AGGTAGTAAGCATGAAGCGCAGTTCAGTTTCCACCGGTGGTGCTGGCCGCCTCTCCATGCAGGA
TTTAAGGTCTCAGGATTTCAATAAACAAGGCCTCCATACCCCTCAAACCAAAGAGAAACCAGCC
TTTGGAAAGTTGAGTATAAACAAACCGACATCTGAAAGAAAAATCTCTGTGTTTGGTAAAAGTT
CTGAAAAAATCAAGGACCCCCGGCCACTTAATGACAAAGCATTCATTCAACAGTGTATTCGACA
ACTCTGTGAGTTTCTTACAGAAAATGGTTATGCATATAGCGTATCCATGAAATCTCTACAAGCT
CCTTCTGTTAAAGACTTCCTAAAGATCTTCACTTTTCTTTATGGCTTCCTGTGCCCTTCATATG
AACTTCCTGACACAAAGTTTGAAGAAGAGGTTCCAAGAATCTTTAGAGATCTTGGGTATCCTTT
TGCATTATCCAAAAGCTCCATGTATACAGTGGGGGCCCCTCATACATGGCCACACATTGTGGCA
GCCTTGGTTTGGCTAATAGACTGCATCAAGTTACATAATGCCATGAAAGAAAGCTCACCTTTGT
TTGATGATGGACAGCCTTGGGGAGAAGAAACTGAAGATGGAATTATGCACAATAAGCTGTTTTT
GGACTACACCATAAAATGCTATGAGAGTTTCATGACTGGTGCTGACAGTTTTGAAGAGATGAAT
GCAGAGTTGCAGTCAAAGCTGAAGGATTTATTTAATGTAGATGCTTCTAAGCTGGAGTCACTAG
CAGCAAAAAATAAAGCATTGAATGAACAAATTGCAAGATTGGAACAAGAAAGAGAAAAAGAACC
GAATCGTCTAGAGTCATTGAGAAAACTGAAAACTTCCTTACAAGCAGATGTTCAAAAATATCAG
GCATACATGAACAATTTGGAGTCTCATTCAGCAATTCTTGACCAGAAATTGAATGGTCTTGATG
AAGAAATTTCTAGAGTAGAACTAGAATATGAAACAATGAAACAGGAGAATACCCGCCTACAGAA
TATTGTTGATAACCAGAAGTACTCAGTTGCAGACATCGAGAGAATAAATCATGAAAGAAATGAA
TTGCAGCAGACCATTAATAAATTAACCAAAGACCTGGAGGCTGAACAACAGCAGCTGTGGAATG
AAGAGCTAAAATATGCCAGAGGCAAGGAGGCGATTGAAACACAATTATCAGAGTATCACAAGTT
GGCCAGAAAATTAAAACTTATCCCTAAGGGTGCTGAAAATTCCAAAGGTTATGACTTTGAAATT
AAGTTTAATCCTGAAGCTGGTGCCAACTGCCTTGTCAAATACAGAGCTCAAGTTTATGTACCAC
TCAAGGAACTCTTGAACCAAACTGAAGAAGAAATTAATAAAGCTCTAAATAAAAAAATGGGGTT
AGAAGATACTTTAGAACAGTTAAATACAATGATAACAGAAAGCAGGAGAGGTGTAAGAACTCTG
AAAGAAGAAGTTCAAAAGCTGGATGATCTTTACCAACAAAAAGTTAAGGAAGCTGAAGAAGAGG
ACAAAAAGTGTGCCAGTGAGCTGGAGTCCTTGGATAAACACAAACATCTGCTAGAGAGTGCTGT
TAATGAGGGCCTCAGTGAAGCTATAAATGAATTAGATGCTATTCAGCGAGAATACCAACTAGTT
GTGCAAACCACAACTGAAGAACGACGAAAAGTGGGAAATAACTTGCAGCGTCTTTTAGAGATGG
TTGCTACACATGTAGGATCTGTGGAGAAACATCTTGAGGTGCAGATTGCTAAAGTTGATAGAGA
GTATGAAGAATATGTGTCTGAAGATCTCTTGGAAAATATTAGAGAGATTGGAGACAAGTATAAG
AAGAAAGCTGCTCTAATTAAGCCTTCTGAGGAATGAAGATGAAATATTGATTATCTAAGCAAGA
ACTTTATTAACTGTAAATTTTTAAATGTCCTTTGTAGGTGTGAAAAATCTCTAACATGTCCTAA
ACCCTTCCTTACAATGAAGTCTTAAGACCGTATCTTTCCAAGCCTGTGAAATATTTTTATATCT
TTTGTAAATCTAGTTCATTAAAGTATGTATAACCTGAAACTA

hide sequence

RefSeq Acc Id:

XM_038482269 ⟹ XP_038338197

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	7	69,012,589 - 69,061,471 (+)	NCBI

RefSeq Acc Id:

XM_038482270 ⟹ XP_038338198

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	7	69,012,589 - 69,061,471 (+)	NCBI

RefSeq Acc Id:

XM_038482271 ⟹ XP_038338199

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	7	69,012,589 - 69,058,169 (+)	NCBI

RefSeq Acc Id:

XM_038543704 ⟹ XP_038399632

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	7	69,329,927 - 69,378,829 (+)	NCBI

RefSeq Acc Id:

XM_038543705 ⟹ XP_038399633

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	7	69,329,927 - 69,378,829 (+)	NCBI

RefSeq Acc Id:

XM_038543706 ⟹ XP_038399634

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	7	69,329,927 - 69,375,526 (+)	NCBI

RefSeq Acc Id:

XM_038576700 ⟹ XP_038432628

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	7	68,723,201 - 68,768,883 (+)	NCBI

RefSeq Acc Id:

XM_038607830 ⟹ XP_038463758

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	7	69,032,710 - 69,081,627 (+)	NCBI

RefSeq Acc Id:

XM_038607831 ⟹ XP_038463759

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	7	69,032,710 - 69,081,627 (+)	NCBI

RefSeq Acc Id:

XM_038607832 ⟹ XP_038463760

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	7	69,032,710 - 69,078,325 (+)	NCBI

RefSeq Acc Id:

XM_038672513 ⟹ XP_038528441

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	7	69,329,940 - 69,378,870 (+)	NCBI

RefSeq Acc Id:

XM_038672514 ⟹ XP_038528442

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	7	69,329,940 - 69,378,870 (+)	NCBI

RefSeq Acc Id:

XM_038672515 ⟹ XP_038528443

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	7	69,329,940 - 69,375,568 (+)	NCBI

RefSeq Acc Id:

XM_537313 ⟹ XP_537313

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	7	69,268,218 - 69,317,126 (+)	NCBI
Dog10K_Boxer_Tasha	7	68,723,201 - 68,772,189 (+)	NCBI

Sequence:

show sequence

TTTCAAATTCGAACTGCGCCGGCGGGTGCGGGGAGGAGTTGGGTGTTTTGGCGGCTGTCGTCCT
GCCTCGCAAATAGTTGCGCGGATTACGGATTCGGCCCTTGGATTGTATCACGAAACTGGAAGAA
AGGTAGTAAGCATGAAGCGCAGTTCAGTTTCCACCGGTGGTGCTGGCCGCCTCTCCATGCAGGA
TTTAAGGTCTCAGGATTTCAATAAACAAGGCCTCCATACCCCTCAAACCAAAGAGAAACCAGCC
TTTGGAAAGTTGAGTATAAACAAACCGACATCTGAAAGAAAAATCTCTGTGTTTGGTAAAAGAA
CTAGTGGACATGGCTCCCGGAATAGTCAATTTGGTATATTTTCCAGTTCTGAAAAAATCAAGGA
CCCCCGGCCACTTAATGACAAAGCATTCATTCAACAGTGTATTCGACAACTCTGTGAGTTTCTT
ACAGAAAATGGTTATGCATATAGCGTATCCATGAAATCTCTACAAGCTCCTTCTGTTAAAGACT
TCCTAAAGATCTTCACTTTTCTTTATGGCTTCCTGTGCCCTTCATATGAACTTCCTGACACAAA
GTTTGAAGAAGAGGTTCCAAGAATCTTTAGAGATCTTGGGTATCCTTTTGCATTATCCAAAAGC
TCCATGTATACAGTGGGGGCCCCTCATACATGGCCACACATTGTGGCAGCCTTGGTTTGGCTAA
TAGACTGCATCAAGTTACATAATGCCATGAAAGAAAGCTCACCTTTGTTTGATGATGGACAGCC
TTGGGGAGAAGAAACTGAAGATGGAATTATGCACAATAAGCTGTTTTTGGACTACACCATAAAA
TGCTATGAGAGTTTCATGACTGGTGCTGACAGTTTTGAAGAGATGAATGCAGAGTTGCAGTCAA
AGCTGAAGGATTTATTTAATGTAGATGCTTCTAAGCTGGAGTCACTAGCAGCAAAAAATAAAGC
ATTGAATGAACAAATTGCAAGATTGGAACAAGAAAGAGAAAAAGAACCGAATCGTCTAGAGTCA
TTGAGAAAACTGAAAACTTCCTTACAAGCAGATGTTCAAAAATATCAGGCATACATGAACAATT
TGGAGTCTCATTCAGCAATTCTTGACCAGAAATTGAATGGTCTTGATGAAGAAATTTCTAGAGT
AGAACTAGAATATGAAACAATGAAACAGGAGAATACCCGCCTACAGAATATTGTTGATAACCAG
AAGTACTCAGTTGCAGACATCGAGAGAATAAATCATGAAAGAAATGAATTGCAGCAGACCATTA
ATAAATTAACCAAAGACCTGGAGGCTGAACAACAGCAGCTGTGGAATGAAGAGCTAAAATATGC
CAGAGGCAAGGAGGCGATTGAAACACAATTATCAGAGTATCACAAGTTGGCCAGAAAATTAAAA
CTTATCCCTAAGGGTGCTGAAAATTCCAAAGGTTATGACTTTGAAATTAAGTTTAATCCTGAAG
CTGGTGCCAACTGCCTTGTCAAATACAGAGCTCAAGTTTATGTACCACTCAAGGAACTCTTGAA
CCAAACTGAAGAAGAAATTAATAAAGCTCTAAATAAAAAAATGGGGTTAGAAGATACTTTAGAA
CAGTTAAATACAATGATAACAGAAAGCAGGAGAGGTGTAAGAACTCTGAAAGAAGAAGTTCAAA
AGCTGGATGATCTTTACCAACAAAAAGTTAAGGAAGCTGAAGAAGAGGACAAAAAGTGTGCCAG
TGAGCTGGAGTCCTTGGATAAACACAAACATCTGCTAGAGAGTGCTGTTAATGAGGGCCTCAGT
GAAGCTATAAATGAATTAGATGCTATTCAGCGAGAATACCAACTAGTTGTGCAAACCACAACTG
AAGAACGACGAAAAGTGGGAAATAACTTGCAGCGTCTTTTAGAGATGGTTGCTACACATGTAGG
ATCTGTGGAGAAACATCTTGAGGTGCAGATTGCTAAAGTTGATAGAGAGTATGAAGAATATGTG
TCTGAAGATCTCTTGGAAAATATTAGAGAGATTGGAGACAAGTATAAGAAGAAAGCTGCTCTAA
TTAAGCCTTCTGAGGAATGAAGATGAAATATTGATTATCTAAGCAAGAACTTTATTAACTGTAA
ATTTTTAAATGTCCTTTGTAGGTGTGAAAAATCTCTAACATGTCCTAAACCCTTCCTTACAATG
AAGTCTTAAGACCGTATCTTTCCAAGCCTGTGAAATATTTTTATATCTTTTGTAAATCTAGTTC
ATTAAAGTATGTATAACCTGAAACTA

hide sequence

Protein Sequences


Protein RefSeqs	XP_022277249	(Get FASTA)	NCBI Sequence Viewer
	XP_038338197	(Get FASTA)	NCBI Sequence Viewer
	XP_038338198	(Get FASTA)	NCBI Sequence Viewer
	XP_038338199	(Get FASTA)	NCBI Sequence Viewer
	XP_038399632	(Get FASTA)	NCBI Sequence Viewer
	XP_038399633	(Get FASTA)	NCBI Sequence Viewer
	XP_038399634	(Get FASTA)	NCBI Sequence Viewer
	XP_038432628	(Get FASTA)	NCBI Sequence Viewer
	XP_038463758	(Get FASTA)	NCBI Sequence Viewer
	XP_038463759	(Get FASTA)	NCBI Sequence Viewer
	XP_038463760	(Get FASTA)	NCBI Sequence Viewer
	XP_038528441	(Get FASTA)	NCBI Sequence Viewer
	XP_038528442	(Get FASTA)	NCBI Sequence Viewer
	XP_038528443	(Get FASTA)	NCBI Sequence Viewer
	XP_537313	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000027183.3
	ENSCAFP00030023196.1
	ENSCAFP00030023311.1
	ENSCAFP00040003093.1
	ENSCAFP00845003490
	ENSCAFP00845003490.1

RefSeq Acc Id:	XP_537313 ⟸ XM_537313
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0ND51 (UniProtKB/TrEMBL), A0A8C0L7M5 (UniProtKB/TrEMBL), A0A8I3ML90 (UniProtKB/TrEMBL)
- Sequence:	show sequence MKRSSVSTGGAGRLSMQDLRSQDFNKQGLHTPQTKEKPAFGKLSINKPTSERKISVFGKRTSGH GSRNSQFGIFSSSEKIKDPRPLNDKAFIQQCIRQLCEFLTENGYAYSVSMKSLQAPSVKDFLKI FTFLYGFLCPSYELPDTKFEEEVPRIFRDLGYPFALSKSSMYTVGAPHTWPHIVAALVWLIDCI KLHNAMKESSPLFDDGQPWGEETEDGIMHNKLFLDYTIKCYESFMTGADSFEEMNAELQSKLKD LFNVDASKLESLAAKNKALNEQIARLEQEREKEPNRLESLRKLKTSLQADVQKYQAYMNNLESH SAILDQKLNGLDEEISRVELEYETMKQENTRLQNIVDNQKYSVADIERINHERNELQQTINKLT KDLEAEQQQLWNEELKYARGKEAIETQLSEYHKLARKLKLIPKGAENSKGYDFEIKFNPEAGAN CLVKYRAQVYVPLKELLNQTEEEINKALNKKMGLEDTLEQLNTMITESRRGVRTLKEEVQKLDD LYQQKVKEAEEEDKKCASELESLDKHKHLLESAVNEGLSEAINELDAIQREYQLVVQTTTEERR KVGNNLQRLLEMVATHVGSVEKHLEVQIAKVDREYEEYVSEDLLENIREIGDKYKKKAALIKPS EE hide sequence

RefSeq Acc Id:

XP_022277249 ⟸ XM_022421541

- Peptide Label:

isoform X2

- Sequence:

show sequence

MKRSSVSTGGAGRLSMQDLRSQDFNKQGLHTPQTKEKPAFGKLSINKPTSERKISVFGKSSEKI
KDPRPLNDKAFIQQCIRQLCEFLTENGYAYSVSMKSLQAPSVKDFLKIFTFLYGFLCPSYELPD
TKFEEEVPRIFRDLGYPFALSKSSMYTVGAPHTWPHIVAALVWLIDCIKLHNAMKESSPLFDDG
QPWGEETEDGIMHNKLFLDYTIKCYESFMTGADSFEEMNAELQSKLKDLFNVDASKLESLAAKN
KALNEQIARLEQEREKEPNRLESLRKLKTSLQADVQKYQAYMNNLESHSAILDQKLNGLDEEIS
RVELEYETMKQENTRLQNIVDNQKYSVADIERINHERNELQQTINKLTKDLEAEQQQLWNEELK
YARGKEAIETQLSEYHKLARKLKLIPKGAENSKGYDFEIKFNPEAGANCLVKYRAQVYVPLKEL
LNQTEEEINKALNKKMGLEDTLEQLNTMITESRRGVRTLKEEVQKLDDLYQQKVKEAEEEDKKC
ASELESLDKHKHLLESAVNEGLSEAINELDAIQREYQLVVQTTTEERRKVGNNLQRLLEMVATH
VGSVEKHLEVQIAKVDREYEEYVSEDLLENIREIGDKYKKKAALIKPSEE

hide sequence

Ensembl Acc Id:

ENSCAFP00000027183 ⟸ ENSCAFT00000029233

Ensembl Acc Id:

ENSCAFP00000052590 ⟸ ENSCAFT00000065585

RefSeq Acc Id:	XP_038338197 ⟸ XM_038482269
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038338198 ⟸ XM_038482270
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038338199 ⟸ XM_038482271
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038463758 ⟸ XM_038607830
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038463759 ⟸ XM_038607831
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038463760 ⟸ XM_038607832
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038528441 ⟸ XM_038672513
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0ND51 (UniProtKB/TrEMBL), A0A8C0L7M5 (UniProtKB/TrEMBL), A0A8I3ML90 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038528442 ⟸ XM_038672514
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038528443 ⟸ XM_038672515
- Peptide Label:	isoform X3
- UniProtKB:	A0A8C0RK53 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038432628 ⟸ XM_038576700
- Peptide Label:	isoform X3
- UniProtKB:	A0A8C0RK53 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038399632 ⟸ XM_038543704
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0L7M5 (UniProtKB/TrEMBL), A0A8C0ND51 (UniProtKB/TrEMBL), A0A8I3ML90 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038399633 ⟸ XM_038543705
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038399634 ⟸ XM_038543706
- Peptide Label:	isoform X3
- UniProtKB:	A0A8C0RK53 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCAFP00845003490 ⟸ ENSCAFT00845004368

Protein Domains

DUF5595

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000018395	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030014379	UniProtKB/TrEMBL
	ENSCAFG00040001905	UniProtKB/TrEMBL
	ENSCAFG00845002475	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000029233.5	UniProtKB/TrEMBL
	ENSCAFT00030026574.1	UniProtKB/TrEMBL
	ENSCAFT00030026707.1	UniProtKB/TrEMBL
	ENSCAFT00040003607.1	UniProtKB/TrEMBL
	ENSCAFT00845004368	ENTREZGENE
	ENSCAFT00845004368.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.418.30	UniProtKB/TrEMBL
	6.10.250.1950	UniProtKB/TrEMBL
InterPro	DUF5595	UniProtKB/TrEMBL
	Kinetochore_Ndc80	UniProtKB/TrEMBL
	Ndc80_sf	UniProtKB/TrEMBL
NCBI Gene	NDC80	ENTREZGENE
PANTHER	KINETOCHORE PROTEIN NDC80 HOMOLOG	UniProtKB/TrEMBL
	PTHR10643	UniProtKB/TrEMBL
Pfam	DUF5595	UniProtKB/TrEMBL
	Ndc80_HEC	UniProtKB/TrEMBL
UniProt	A0A8C0L7M5	ENTREZGENE
	A0A8C0ND51	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0RK53	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3ML90	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:43670	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2019-04-16	NDC80	NDC80 kinetochore complex component		NDC80, kinetochore complex component	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD