WDR75 (WD repeat domain 75) - Rat Genome Database

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Gene: WDR75 (WD repeat domain 75) Canis lupus familiaris
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Symbol: WDR75
Name: WD repeat domain 75
RGD ID: 12200583
Description: INVOLVED IN positive regulation of rRNA processing (inferred); positive regulation of transcription by RNA polymerase I (inferred); ASSOCIATED WITH Ehlers-Danlos Syndrome Type 4 (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN nucleolus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Also known as: WD repeat-containing protein 75
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.137157,400 - 191,127 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl37157,455 - 190,916 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha371,127,984 - 1,162,166 (+)NCBI
ROS_Cfam_1.03746,253 - 80,392 (+)NCBI
UMICH_Zoey_3.13758,984 - 93,113 (+)NCBI
UNSW_CanFamBas_1.03726,641 - 61,083 (+)NCBI
UU_Cfam_GSD_1.03755,367 - 89,511 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleolus  (IEA)

References

Genomics

Comparative Map Data
WDR75
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.137157,400 - 191,127 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl37157,455 - 190,916 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha371,127,984 - 1,162,166 (+)NCBI
ROS_Cfam_1.03746,253 - 80,392 (+)NCBI
UMICH_Zoey_3.13758,984 - 93,113 (+)NCBI
UNSW_CanFamBas_1.03726,641 - 61,083 (+)NCBI
UU_Cfam_GSD_1.03755,367 - 89,511 (+)NCBI
WDR75
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2189,441,446 - 189,475,552 (+)EnsemblGRCh38hg38GRCh38
GRCh382189,441,473 - 189,475,556 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372190,306,200 - 190,340,278 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362190,014,404 - 190,048,509 (+)NCBINCBI36hg18NCBI36
Celera2183,901,218 - 183,935,325 (+)NCBI
Cytogenetic Map2q32.2NCBI
HuRef2182,165,790 - 182,199,902 (+)NCBIHuRef
CHM1_12190,312,056 - 190,346,185 (+)NCBICHM1_1
Wdr75
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39145,834,313 - 45,862,798 (+)NCBIGRCm39mm39
GRCm39 Ensembl145,834,326 - 45,862,779 (+)Ensembl
GRCm38145,795,153 - 45,823,638 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl145,795,166 - 45,823,619 (+)EnsemblGRCm38mm10GRCm38
MGSCv37145,852,346 - 45,880,458 (+)NCBIGRCm37mm9NCBIm37
MGSCv36145,740,047 - 45,768,159 (+)NCBImm8
Celera146,127,754 - 46,155,866 (+)NCBICelera
Cytogenetic Map1C1.1NCBI
Wdr75
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2947,903,166 - 47,933,399 (+)NCBI
Rnor_6.0 Ensembl952,687,868 - 52,717,809 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0952,687,845 - 52,717,808 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0952,353,665 - 52,383,624 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4944,849,323 - 44,873,180 (+)NCBIRGSC3.4rn4RGSC3.4
Celera945,578,427 - 45,602,289 (+)NCBICelera
Cytogenetic Map9q22NCBI
Wdr75
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554039,352,615 - 9,383,206 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554039,352,615 - 9,383,206 (-)NCBIChiLan1.0ChiLan1.0
WDR75
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12B194,668,211 - 194,702,343 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B194,668,211 - 194,702,343 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02B76,748,487 - 76,782,649 (+)NCBIMhudiblu_PPA_v0panPan3
Wdr75
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303148,308,723 - 148,335,802 (+)NCBI
SpeTri2.0NW_0049365068,502,795 - 8,529,305 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WDR75
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1593,981,215 - 94,026,707 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11593,981,054 - 94,026,479 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215104,503,605 - 104,547,626 (+)NCBISscrofa10.2Sscrofa10.2susScr3
WDR75
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11074,953,086 - 74,989,662 (+)NCBI
ChlSab1.1 Ensembl1074,953,072 - 74,991,458 (+)Ensembl
Vero_WHO_p1.0NW_023666040124,487,868 - 124,524,883 (-)NCBI
Wdr75
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624899786,447 - 818,310 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 16 4 6 9 10 3
Low 5 5 6 6 2 6 6 3 8 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000014861   ⟹   ENSCAFP00000013753
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl37157,455 - 190,916 (+)Ensembl
RefSeq Acc Id: XM_038447356   ⟹   XP_038303284
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.03746,253 - 80,392 (+)NCBI
RefSeq Acc Id: XM_038521414   ⟹   XP_038377342
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.13758,984 - 93,113 (+)NCBI
RefSeq Acc Id: XM_038585120   ⟹   XP_038441048
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.03755,367 - 89,511 (+)NCBI
RefSeq Acc Id: XM_038649531   ⟹   XP_038505459
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.03726,641 - 61,083 (+)NCBI
RefSeq Acc Id: XM_545565   ⟹   XP_545565
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.137157,400 - 191,127 (+)NCBI
Dog10K_Boxer_Tasha371,127,984 - 1,162,166 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_038303284 (Get FASTA)   NCBI Sequence Viewer  
  XP_038377342 (Get FASTA)   NCBI Sequence Viewer  
  XP_038441048 (Get FASTA)   NCBI Sequence Viewer  
  XP_038505459 (Get FASTA)   NCBI Sequence Viewer  
  XP_545565 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_545565   ⟸   XM_545565
- UniProtKB: E2RFM0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000013753   ⟸   ENSCAFT00000014861
RefSeq Acc Id: XP_038377342   ⟸   XM_038521414
RefSeq Acc Id: XP_038505459   ⟸   XM_038649531
RefSeq Acc Id: XP_038303284   ⟸   XM_038447356
RefSeq Acc Id: XP_038441048   ⟸   XM_038585120
Protein Domains
WD_REPEATS_REGION

Promoters
RGD ID:13689096
Promoter ID:EPDNEW_C7165
Type:multiple initiation site
Name:WDR75_1
Description:WD repeat domain 75
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.137157,453 - 157,513EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000009325 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00000013753 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000014861 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
InterPro Quinoprotein_ADH-like_supfam UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_dom UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
KEGG Report cfa:488443 UniProtKB/TrEMBL
NCBI Gene WDR75 ENTREZGENE
Pfam WD40 UniProtKB/TrEMBL
PROSITE WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
SMART WD40 UniProtKB/TrEMBL
Superfamily-SCOP SSF50978 UniProtKB/TrEMBL
  SSF50998 UniProtKB/TrEMBL
UniProt E2RFM0 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:48387 ENTREZGENE