PHKG2 (phosphorylase kinase catalytic subunit gamma 2) - Rat Genome Database

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Gene: PHKG2 (phosphorylase kinase catalytic subunit gamma 2) Canis lupus familiaris
Analyze
Symbol: PHKG2
Name: phosphorylase kinase catalytic subunit gamma 2
RGD ID: 12198932
Description: ENCODES a protein that exhibits ATP binding (ortholog); calmodulin binding (ortholog); enzyme binding (ortholog); INVOLVED IN glycogen metabolic process (ortholog); positive regulation of glycogen catabolic process (ortholog); protein phosphorylation (ortholog); PARTICIPATES IN glycogen degradation pathway; ASSOCIATED WITH branched-chain keto acid dehydrogenase kinase deficiency (ortholog); Fibrosis (ortholog); generalized epilepsy with febrile seizures plus 9 (ortholog); FOUND IN phosphorylase kinase complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: phosphorylase b kinase gamma catalytic chain, liver/testis isoform
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1617,418,927 - 17,428,431 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl617,418,926 - 17,428,359 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha618,994,038 - 19,003,354 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0617,550,838 - 17,560,162 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl617,550,017 - 17,560,120 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1617,351,106 - 17,360,420 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0617,268,801 - 17,278,114 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0617,581,612 - 17,590,927 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
PHKG2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1617,418,927 - 17,428,431 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl617,418,926 - 17,428,359 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha618,994,038 - 19,003,354 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0617,550,838 - 17,560,162 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl617,550,017 - 17,560,120 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1617,351,106 - 17,360,420 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0617,268,801 - 17,278,114 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0617,581,612 - 17,590,927 (-)NCBIUU_Cfam_GSD_1.0
PHKG2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381630,748,425 - 30,761,176 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1630,748,293 - 30,761,176 (+)EnsemblGRCh38hg38GRCh38
GRCh371630,759,746 - 30,772,497 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361630,667,238 - 30,676,183 (+)NCBINCBI36Build 36hg18NCBI36
Build 341630,667,237 - 30,676,183NCBI
Celera1629,524,946 - 29,537,900 (-)NCBICelera
Cytogenetic Map16p11.2NCBI
HuRef1628,322,420 - 28,335,306 (+)NCBIHuRef
CHM1_11632,076,842 - 32,089,639 (+)NCBICHM1_1
T2T-CHM13v2.01631,135,424 - 31,148,597 (+)NCBIT2T-CHM13v2.0
Phkg2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397127,169,252 - 127,182,479 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7127,172,512 - 127,182,479 (+)EnsemblGRCm39 Ensembl
GRCm387127,573,345 - 127,583,307 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7127,573,340 - 127,583,307 (+)EnsemblGRCm38mm10GRCm38
MGSCv377134,716,862 - 134,726,821 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367127,364,552 - 127,374,453 (+)NCBIMGSCv36mm8
Celera7127,418,345 - 127,428,215 (+)NCBICelera
Cytogenetic Map7F3NCBI
cM Map769.6NCBI
Phkg2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81191,614,738 - 191,627,615 (+)NCBIGRCr8
mRatBN7.21182,184,362 - 182,197,124 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1182,184,650 - 182,197,124 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1190,535,160 - 190,547,687 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01197,721,243 - 197,733,769 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01190,391,742 - 190,404,269 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01199,019,298 - 199,032,053 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1199,019,289 - 199,032,052 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01206,027,201 - 206,039,931 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41186,858,077 - 186,870,601 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11187,008,018 - 187,020,482 (+)NCBI
Celera1179,836,521 - 179,848,906 (+)NCBICelera
Cytogenetic Map1q37NCBI
Phkg2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554937,612,251 - 7,622,486 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554937,612,251 - 7,622,486 (+)NCBIChiLan1.0ChiLan1.0
PHKG2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21833,953,128 - 33,962,765 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11638,754,587 - 38,764,224 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01624,211,929 - 24,221,756 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11631,115,033 - 31,124,428 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1631,115,033 - 31,127,216 (+)Ensemblpanpan1.1panPan2
Phkg2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344125,041,362 - 125,052,624 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650113,139,970 - 13,150,484 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493650113,139,182 - 13,150,507 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PHKG2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl317,639,996 - 17,656,618 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1317,640,790 - 17,656,765 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2318,087,281 - 18,103,213 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PHKG2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1527,438,975 - 27,444,922 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660682,030,430 - 2,040,384 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Phkg2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478213,871,130 - 13,881,001 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478213,864,002 - 13,880,568 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PHKG2
46 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 22 6 6 6 6 12 8 10 6
Low 5 6
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000026395   ⟹   ENSCAFP00000024512
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl617,418,926 - 17,428,359 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845023860   ⟹   ENSCAFP00845018737
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl617,550,017 - 17,560,120 (-)Ensembl
RefSeq Acc Id: XM_005621272   ⟹   XP_005621329
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1617,418,927 - 17,428,387 (-)NCBI
Dog10K_Boxer_Tasha618,994,038 - 19,003,304 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038478539   ⟹   XP_038334467
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1617,351,106 - 17,360,420 (-)NCBI
RefSeq Acc Id: XM_038478540   ⟹   XP_038334468
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1617,351,106 - 17,360,370 (-)NCBI
RefSeq Acc Id: XM_038539789   ⟹   XP_038395717
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0617,581,612 - 17,590,927 (-)NCBI
RefSeq Acc Id: XM_038539790   ⟹   XP_038395718
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0617,581,612 - 17,590,877 (-)NCBI
RefSeq Acc Id: XM_038603869   ⟹   XP_038459797
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0617,268,801 - 17,278,114 (-)NCBI
RefSeq Acc Id: XM_038603870   ⟹   XP_038459798
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0617,268,801 - 17,278,064 (-)NCBI
RefSeq Acc Id: XM_038668593   ⟹   XP_038524521
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0617,550,838 - 17,560,162 (-)NCBI
RefSeq Acc Id: XM_038668594   ⟹   XP_038524522
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0617,550,838 - 17,560,112 (-)NCBI
RefSeq Acc Id: XM_843877   ⟹   XP_848970
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1617,418,927 - 17,428,431 (-)NCBI
Dog10K_Boxer_Tasha618,994,038 - 19,003,354 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_848970   ⟸   XM_843877
- UniProtKB: A0A8C0SFP4 (UniProtKB/TrEMBL),   A0A8I3NJX4 (UniProtKB/TrEMBL),   A0A8C0L027 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005621329   ⟸   XM_005621272
- UniProtKB: A0A8C0SFP4 (UniProtKB/TrEMBL),   A0A8I3NJX4 (UniProtKB/TrEMBL),   A0A8C0L027 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000024512   ⟸   ENSCAFT00000026395
RefSeq Acc Id: XP_038334467   ⟸   XM_038478539
RefSeq Acc Id: XP_038334468   ⟸   XM_038478540
RefSeq Acc Id: XP_038459797   ⟸   XM_038603869
RefSeq Acc Id: XP_038459798   ⟸   XM_038603870
RefSeq Acc Id: XP_038524521   ⟸   XM_038668593
- UniProtKB: A0A8C0SFP4 (UniProtKB/TrEMBL),   A0A8I3NJX4 (UniProtKB/TrEMBL),   A0A8C0L027 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038524522   ⟸   XM_038668594
- UniProtKB: A0A8C0SFP4 (UniProtKB/TrEMBL),   A0A8I3NJX4 (UniProtKB/TrEMBL),   A0A8C0L027 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038395717   ⟸   XM_038539789
- UniProtKB: A0A8C0L027 (UniProtKB/TrEMBL),   A0A8C0SFP4 (UniProtKB/TrEMBL),   A0A8I3NJX4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038395718   ⟸   XM_038539790
- UniProtKB: A0A8C0L027 (UniProtKB/TrEMBL),   A0A8C0SFP4 (UniProtKB/TrEMBL),   A0A8I3NJX4 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845018737   ⟸   ENSCAFT00845023860
Protein Domains
Protein kinase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000016653 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030002728 UniProtKB/TrEMBL
  ENSCAFG00040012970 UniProtKB/TrEMBL
  ENSCAFG00845013387 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000026395.5 UniProtKB/TrEMBL
  ENSCAFT00030005070.1 UniProtKB/TrEMBL
  ENSCAFT00040023940.1 UniProtKB/TrEMBL
  ENSCAFT00845023860 ENTREZGENE
  ENSCAFT00845023860.1 UniProtKB/TrEMBL
Gene3D-CATH Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro Kinase-like_dom_sf UniProtKB/TrEMBL
  Phosph_kin_gamma UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
KEGG Report cfa:607275 UniProtKB/TrEMBL
NCBI Gene PHKG2 ENTREZGENE
PANTHER PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, LIVER/TESTIS ISOFORM UniProtKB/TrEMBL
  SERINE/THREONINE-PROTEIN KINASE UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/TrEMBL
PRINTS PHOSPHBKNASE UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
UniProt A0A8C0L027 ENTREZGENE
  A0A8C0SFP4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NJX4 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:44500 ENTREZGENE