ERG28 (ergosterol biosynthesis 28 homolog) - Rat Genome Database

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Gene: ERG28 (ergosterol biosynthesis 28 homolog) Canis lupus familiaris
Analyze
Symbol: ERG28
Name: ergosterol biosynthesis 28 homolog
RGD ID: 12196607
Description: ENCODES a protein that exhibits identical protein binding (ortholog); ASSOCIATED WITH intellectual disability (ortholog); FOUND IN transport vesicle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: C8H14orf1; chromosome 8 open reading frame, human C14orf1; ergosterol biosynthetic protein 28 homolog; probable ergosterol biosynthetic protein 28
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1848,642,610 - 48,651,637 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl848,643,200 - 48,651,306 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha848,325,527 - 48,334,317 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0848,866,790 - 48,875,591 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1848,539,642 - 48,548,424 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0848,561,072 - 48,569,861 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0848,957,300 - 48,966,096 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ERG28
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1848,642,610 - 48,651,637 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl848,643,200 - 48,651,306 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha848,325,527 - 48,334,317 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0848,866,790 - 48,875,591 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1848,539,642 - 48,548,424 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0848,561,072 - 48,569,861 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0848,957,300 - 48,966,096 (-)NCBIUU_Cfam_GSD_1.0
ERG28
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381475,649,791 - 75,660,876 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1475,649,791 - 75,660,876 (-)EnsemblGRCh38hg38GRCh38
GRCh371476,116,134 - 76,127,219 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361475,185,884 - 75,196,912 (-)NCBINCBI36Build 36hg18NCBI36
Build 341475,185,883 - 75,196,912NCBI
Celera1456,155,336 - 56,165,643 (-)NCBICelera
Cytogenetic Map14q24.3NCBI
HuRef1456,285,182 - 56,295,497 (-)NCBIHuRef
CHM1_11476,054,996 - 76,065,305 (-)NCBICHM1_1
T2T-CHM13v2.01469,858,902 - 69,869,980 (-)NCBIT2T-CHM13v2.0
Erg28
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391285,862,221 - 85,871,667 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1285,862,222 - 85,871,324 (-)EnsemblGRCm39 Ensembl
GRCm381285,815,447 - 85,824,893 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1285,815,448 - 85,824,550 (-)EnsemblGRCm38mm10GRCm38
MGSCv371287,156,405 - 87,165,495 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361286,704,558 - 86,713,648 (-)NCBIMGSCv36mm8
Celera1287,275,694 - 87,284,679 (-)NCBICelera
Cytogenetic Map12D2NCBI
cM Map1239.81NCBI
Erg28
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86111,205,102 - 111,214,068 (-)NCBIGRCr8
mRatBN7.26105,474,112 - 105,483,078 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6105,474,113 - 105,483,078 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6105,643,750 - 105,652,716 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06105,942,626 - 105,951,592 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06105,312,269 - 105,321,237 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06109,683,252 - 109,692,218 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6109,683,253 - 109,692,218 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06118,991,548 - 119,000,513 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46109,934,787 - 109,945,923 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16109,938,317 - 109,949,121 (-)NCBI
Celera6103,300,790 - 103,309,751 (-)NCBICelera
Cytogenetic Map6q31NCBI
Erg28
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495561299,119 - 109,525 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495561299,107 - 109,679 (-)NCBIChiLan1.0ChiLan1.0
ERG28
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21576,736,592 - 76,746,575 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11475,953,089 - 75,963,080 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01456,205,947 - 56,216,227 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11475,048,692 - 75,058,970 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1475,048,692 - 75,058,970 (-)Ensemblpanpan1.1panPan2
Erg28
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864027,345,935 - 27,354,631 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364884,714,374 - 4,722,941 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364884,714,337 - 4,722,928 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ERG28
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl798,811,716 - 98,821,930 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1798,811,710 - 98,822,641 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27104,709,854 - 104,709,986 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ERG28
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12452,895,060 - 52,905,265 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2452,894,420 - 52,905,224 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605341,113,289 - 41,123,583 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Erg28
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473426,021,880 - 26,030,440 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473426,021,761 - 26,031,026 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ERG28
86 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 5 22 6 6 6 6 12 8 10 6
Low 6
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000027004   ⟹   ENSCAFP00000025105
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl848,643,200 - 48,651,306 (-)Ensembl
RefSeq Acc Id: XM_014116088   ⟹   XP_013971563
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1848,642,610 - 48,651,637 (-)NCBI
Dog10K_Boxer_Tasha848,325,527 - 48,334,317 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038483859   ⟹   XP_038339787
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1848,539,642 - 48,548,424 (-)NCBI
RefSeq Acc Id: XM_038483860   ⟹   XP_038339788
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1848,539,642 - 48,548,423 (-)NCBI
RefSeq Acc Id: XM_038545339   ⟹   XP_038401267
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0848,957,300 - 48,966,096 (-)NCBI
RefSeq Acc Id: XM_038545340   ⟹   XP_038401268
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0848,957,300 - 48,966,095 (-)NCBI
RefSeq Acc Id: XM_038609439   ⟹   XP_038465367
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0848,561,072 - 48,569,861 (-)NCBI
RefSeq Acc Id: XM_038609440   ⟹   XP_038465368
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0848,561,072 - 48,569,860 (-)NCBI
RefSeq Acc Id: XM_038674262   ⟹   XP_038530190
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0848,866,790 - 48,875,591 (-)NCBI
RefSeq Acc Id: XM_038674263   ⟹   XP_038530191
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0848,866,790 - 48,875,590 (-)NCBI
RefSeq Acc Id: XM_849684   ⟹   XP_854777
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1848,642,610 - 48,651,629 (-)NCBI
Dog10K_Boxer_Tasha848,325,527 - 48,334,316 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_854777   ⟸   XM_849684
- Peptide Label: isoform X2
- UniProtKB: A0A8C0SNU7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013971563   ⟸   XM_014116088
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSCAFP00000025105   ⟸   ENSCAFT00000027004
RefSeq Acc Id: XP_038339787   ⟸   XM_038483859
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038339788   ⟸   XM_038483860
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038465367   ⟸   XM_038609439
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038465368   ⟸   XM_038609440
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038530190   ⟸   XM_038674262
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038530191   ⟸   XM_038674263
- Peptide Label: isoform X2
- UniProtKB: A0A8C0SNU7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038401267   ⟸   XM_038545339
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038401268   ⟸   XM_038545340
- Peptide Label: isoform X2
- UniProtKB: A0A8C0SNU7 (UniProtKB/TrEMBL)

Promoters
RGD ID:13684288
Promoter ID:EPDNEW_C2356
Type:initiation region
Name:ERG28_1
Description:ergosterol biosynthesis 28 homolog
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1848,651,357 - 48,651,417EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000017054 Ensembl
  ENSCAFG00000051278 UniProtKB/TrEMBL
  ENSCAFG00030016248 UniProtKB/TrEMBL
  ENSCAFG00040014978 UniProtKB/TrEMBL
  ENSCAFG00845015573 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000104401.1 UniProtKB/TrEMBL
  ENSCAFT00030029905.1 UniProtKB/TrEMBL
  ENSCAFT00040027595.1 UniProtKB/TrEMBL
  ENSCAFT00845027777.1 UniProtKB/TrEMBL
InterPro Erg28 UniProtKB/TrEMBL
NCBI Gene C8H14orf1 ENTREZGENE
PANTHER ERGOSTEROL BIOSYNTHETIC PROTEIN 28 HOMOLOG UniProtKB/TrEMBL
  PTHR15451 UniProtKB/TrEMBL
Pfam Erg28 UniProtKB/TrEMBL
UniProt A0A8C0SNU7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NLR2_CANLF UniProtKB/TrEMBL
  A0A8P0TL20_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:40449 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-05-30 ERG28  ergosterol biosynthesis 28 homolog  C8H14orf1  chromosome 8 open reading frame, human C14orf1  Symbol and/or name change 5135510 APPROVED