FCN2 (ficolin 2) - Rat Genome Database

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Gene: FCN2 (ficolin 2) Canis lupus familiaris
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Symbol: FCN2
Name: ficolin 2
RGD ID: 12194986
Description: ENCODES a protein that exhibits G protein-coupled receptor binding (inferred); pattern recognition receptor activity (inferred); sialic acid binding (inferred); INVOLVED IN cell surface pattern recognition receptor signaling pathway (inferred); G protein-coupled receptor signaling pathway (inferred); negative regulation of viral entry into host cell (inferred); ASSOCIATED WITH Ehlers-Danlos syndrome classic type 1 (ortholog); Experimental Liver Cirrhosis (ortholog); Monoclonal B-Cell Lymphocytosis (ortholog); FOUND IN extrinsic component of external side of plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Also known as: FCN1; ficolin (collagen/fibrinogen domain containing) 1; ficolin-1-like; ficolin-2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1950,868,942 - 50,876,001 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl950,868,973 - 50,875,792 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha950,152,289 - 50,159,350 (+)NCBI
ROS_Cfam_1.0951,746,147 - 51,753,208 (+)NCBI
UMICH_Zoey_3.1950,506,401 - 50,513,474 (+)NCBI
UNSW_CanFamBas_1.0950,850,289 - 50,857,359 (+)NCBI
UU_Cfam_GSD_1.0950,927,946 - 50,935,059 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

Genomics

Comparative Map Data
FCN2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1950,868,942 - 50,876,001 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl950,868,973 - 50,875,792 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha950,152,289 - 50,159,350 (+)NCBI
ROS_Cfam_1.0951,746,147 - 51,753,208 (+)NCBI
UMICH_Zoey_3.1950,506,401 - 50,513,474 (+)NCBI
UNSW_CanFamBas_1.0950,850,289 - 50,857,359 (+)NCBI
UU_Cfam_GSD_1.0950,927,946 - 50,935,059 (+)NCBI
FCN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl9134,903,232 - 134,917,912 (-)EnsemblGRCh38hg38GRCh38
GRCh389134,903,232 - 134,917,912 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh379137,795,078 - 137,809,758 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369136,941,253 - 136,949,630 (-)NCBINCBI36hg18NCBI36
Build 349135,027,380 - 135,035,754NCBI
Celera9108,315,253 - 108,323,628 (-)NCBI
Cytogenetic Map9q34.3NCBI
HuRef9107,265,062 - 107,273,437 (-)NCBIHuRef
CHM1_19137,950,267 - 137,958,642 (-)NCBICHM1_1
Fcnb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39227,966,491 - 27,974,921 (-)NCBIGRCm39mm39
GRCm39 Ensembl227,966,390 - 27,974,897 (-)Ensembl
GRCm38228,076,479 - 28,084,910 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl228,076,378 - 28,084,885 (-)EnsemblGRCm38mm10GRCm38
MGSCv37227,931,999 - 27,940,398 (-)NCBIGRCm37mm9NCBIm37
MGSCv36227,898,488 - 27,906,887 (-)NCBImm8
Celera227,779,281 - 27,787,680 (-)NCBICelera
Cytogenetic Map2A3NCBI
Fcnb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2311,393,771 - 11,402,198 (-)NCBI
Rnor_6.0 Ensembl36,617,751 - 6,626,284 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.036,617,816 - 6,626,193 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0311,974,691 - 11,983,068 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.437,010,989 - 7,019,366 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.137,011,288 - 7,019,666 (-)NCBI
Celera36,185,644 - 6,194,021 (-)NCBICelera
Cytogenetic Map3p12NCBI
Fcn1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555133,687,232 - 3,698,673 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555133,690,550 - 3,697,785 (-)NCBIChiLan1.0ChiLan1.0
FCN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.19135,040,722 - 135,049,105 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9135,040,310 - 135,049,111 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v09106,039,315 - 106,047,648 (-)NCBIMhudiblu_PPA_v0panPan3
FCN2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1274,103,877 - 274,111,970 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11274,106,276 - 274,111,970 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21308,195,158 - 308,203,079 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FCN1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1123,227,790 - 3,236,161 (+)NCBI
Vero_WHO_p1.0NW_0236660581,894,000 - 1,902,427 (-)NCBI
Fcn1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247602,743,996 - 2,751,116 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system nervous system reproductive system respiratory system adipose tissue
High
Medium 8 6 6
Low 9 6 10
Below cutoff 5 3 3 2 2 8 8 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000043238   ⟹   ENSCAFP00000041594
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl950,868,973 - 50,875,792 (+)Ensembl
RefSeq Acc Id: XM_022423640   ⟹   XP_022279348
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1950,870,386 - 50,876,001 (+)NCBI
Sequence:
RefSeq Acc Id: XM_022423641   ⟹   XP_022279349
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1950,870,386 - 50,876,001 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038487014   ⟹   XP_038342942
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1950,506,401 - 50,513,474 (+)NCBI
RefSeq Acc Id: XM_038548865   ⟹   XP_038404793
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0950,927,946 - 50,935,059 (+)NCBI
RefSeq Acc Id: XM_038612815   ⟹   XP_038468743
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0950,850,289 - 50,857,359 (+)NCBI
RefSeq Acc Id: XM_038678115   ⟹   XP_038534043
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0951,746,147 - 51,753,208 (+)NCBI
RefSeq Acc Id: XM_845214   ⟹   XP_850307
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1950,868,942 - 50,876,001 (+)NCBI
Dog10K_Boxer_Tasha950,152,289 - 50,159,350 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_038342942 (Get FASTA)   NCBI Sequence Viewer  
  XP_038404793 (Get FASTA)   NCBI Sequence Viewer  
  XP_038468743 (Get FASTA)   NCBI Sequence Viewer  
  XP_038534043 (Get FASTA)   NCBI Sequence Viewer  
  XP_850307 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_850307   ⟸   XM_845214
- UniProtKB: J9P7F7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022279349   ⟸   XM_022423641
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_022279348   ⟸   XM_022423640
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSCAFP00000041594   ⟸   ENSCAFT00000043238
RefSeq Acc Id: XP_038342942   ⟸   XM_038487014
RefSeq Acc Id: XP_038468743   ⟸   XM_038612815
RefSeq Acc Id: XP_038534043   ⟸   XM_038678115
RefSeq Acc Id: XP_038404793   ⟸   XM_038548865
Protein Domains
Fibrinogen C-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000030630 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00000041594 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000043238 UniProtKB/TrEMBL
Gene3D-CATH 3.90.215.10 UniProtKB/TrEMBL
  4.10.530.10 UniProtKB/TrEMBL
InterPro Collagen UniProtKB/TrEMBL
  Fibrinogen-like_C UniProtKB/TrEMBL
  Fibrinogen_a/b/g_C_1 UniProtKB/TrEMBL
  Fibrinogen_a/b/g_C_2 UniProtKB/TrEMBL
  Fibrinogen_a/b/g_C_dom UniProtKB/TrEMBL
  Fibrinogen_CS UniProtKB/TrEMBL
NCBI Gene FCN2 ENTREZGENE
Pfam Collagen UniProtKB/TrEMBL
  Fibrinogen_C UniProtKB/TrEMBL
PROSITE FIBRINOGEN_C_1 UniProtKB/TrEMBL
  FIBRINOGEN_C_2 UniProtKB/TrEMBL
SMART FBG UniProtKB/TrEMBL
Superfamily-SCOP SSF56496 UniProtKB/TrEMBL
UniProt J9P7F7 ENTREZGENE, UniProtKB/TrEMBL