ABHD17C (abhydrolase domain containing 17C, depalmitoylase) - Rat Genome Database

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Gene: ABHD17C (abhydrolase domain containing 17C, depalmitoylase) Canis lupus familiaris
Analyze
Symbol: ABHD17C
Name: abhydrolase domain containing 17C, depalmitoylase
RGD ID: 12192772
Description: ENCODES a protein that exhibits palmitoyl-(protein) hydrolase activity (inferred); INVOLVED IN macromolecule depalmitoylation (inferred); negative regulation of protein localization to microtubule (inferred); positive regulation of protein localization to endosome (inferred); ASSOCIATED WITH Bloom syndrome (ortholog); colorectal cancer (ortholog); genetic disease (ortholog); FOUND IN glutamatergic synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: abhydrolase domain containing 17C; alpha/beta hydrolase domain-containing protein 17C; FAM108C1; family with sequence similarity 108, member C1; LOC488767
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1356,881,405 - 56,928,305 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha359,530,349 - 59,578,106 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0357,304,187 - 57,351,926 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl357,304,187 - 57,353,444 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1356,814,246 - 56,861,971 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0357,020,436 - 57,068,329 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0357,359,618 - 57,407,376 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
ABHD17C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1356,881,405 - 56,928,305 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha359,530,349 - 59,578,106 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0357,304,187 - 57,351,926 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl357,304,187 - 57,353,444 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1356,814,246 - 56,861,971 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0357,020,436 - 57,068,329 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0357,359,618 - 57,407,376 (-)NCBIUU_Cfam_GSD_1.0
ABHD17C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381580,695,310 - 80,755,621 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1580,679,684 - 80,755,621 (+)EnsemblGRCh38hg38GRCh38
GRCh371580,987,651 - 81,047,962 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361578,774,707 - 78,835,017 (+)NCBINCBI36Build 36hg18NCBI36
Celera1557,925,147 - 57,985,463 (+)NCBICelera
Cytogenetic Map15q25.1NCBI
HuRef1557,745,874 - 57,806,199 (+)NCBIHuRef
CHM1_11581,105,630 - 81,165,886 (+)NCBICHM1_1
T2T-CHM13v2.01578,558,868 - 78,619,168 (+)NCBIT2T-CHM13v2.0
Abhd17c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39783,758,564 - 83,801,101 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl783,758,564 - 83,801,101 (-)EnsemblGRCm39 Ensembl
GRCm38784,109,356 - 84,151,893 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl784,109,356 - 84,151,893 (-)EnsemblGRCm38mm10GRCm38
MGSCv37791,257,866 - 91,300,403 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36783,985,544 - 84,028,078 (-)NCBIMGSCv36mm8
Celera781,514,016 - 81,556,779 (-)NCBICelera
Cytogenetic Map7D3NCBI
cM Map748.35NCBI
Abhd17c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81147,493,755 - 147,534,715 (-)NCBIGRCr8
mRatBN7.21138,084,632 - 138,125,595 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1138,084,634 - 138,125,595 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1146,025,382 - 146,066,369 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01153,194,395 - 153,235,385 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01146,069,595 - 146,110,583 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01146,248,505 - 146,289,465 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1146,248,503 - 146,289,465 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01147,177,240 - 147,218,200 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41140,382,433 - 140,423,393 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11140,460,837 - 140,617,700 (-)NCBI
Celera1130,105,101 - 130,146,062 (-)NCBICelera
Cytogenetic Map1q31NCBI
Abhd17c
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541611,495,651 - 11,543,405 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541611,495,651 - 11,543,276 (+)NCBIChiLan1.0ChiLan1.0
ABHD17C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21669,961,549 - 70,022,177 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11574,123,788 - 74,184,270 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01559,676,295 - 59,736,771 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11578,633,494 - 78,693,159 (+)NCBIpanpan1.1PanPan1.1panPan2
Abhd17c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640126,369,887 - 126,425,663 (+)NCBIHiC_Itri_2
SpeTri2.0NW_00493648319,908,853 - 19,964,627 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ABHD17C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl749,540,879 - 49,599,319 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1749,540,698 - 49,599,323 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2755,050,036 - 55,108,571 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ABHD17C
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1262,633,997 - 2,695,187 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666048139,191,530 - 139,252,924 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Abhd17c
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476821,046,247 - 21,094,399 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476821,045,019 - 21,094,621 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ABHD17C
576 total Variants

Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00845008865   ⟹   ENSCAFP00845006984
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl357,304,187 - 57,353,444 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845008876   ⟹   ENSCAFP00845006992
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl357,304,187 - 57,351,887 (-)Ensembl
RefSeq Acc Id: XM_038472059   ⟹   XP_038327987
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1356,814,246 - 56,861,971 (-)NCBI
RefSeq Acc Id: XM_038476793   ⟹   XP_038332721
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha359,530,349 - 59,578,106 (-)NCBI
RefSeq Acc Id: XM_038532997   ⟹   XP_038388925
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0357,359,618 - 57,407,376 (-)NCBI
RefSeq Acc Id: XM_038597328   ⟹   XP_038453256
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0357,020,436 - 57,068,329 (-)NCBI
RefSeq Acc Id: XM_038661504   ⟹   XP_038517432
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0357,304,187 - 57,351,926 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_038327987   ⟸   XM_038472059
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038453256   ⟸   XM_038597328
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038517432   ⟸   XM_038661504
- Peptide Label: isoform X1
- UniProtKB: A0A8C0Q259 (UniProtKB/TrEMBL),   A0A8I3MMS1 (UniProtKB/TrEMBL),   A0A8C0KP59 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038332721   ⟸   XM_038476793
- Peptide Label: isoform X1
- UniProtKB: A0A8P0PM00 (UniProtKB/TrEMBL),   A0A8C0KP59 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038388925   ⟸   XM_038532997
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KP59 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845006984   ⟸   ENSCAFT00845008865
RefSeq Acc Id: ENSCAFP00845006992   ⟸   ENSCAFT00845008876
Protein Domains
Serine aminopeptidase S33


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000055923 UniProtKB/TrEMBL
  ENSCAFG00040000510 UniProtKB/TrEMBL
  ENSCAFG00845004955 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000106614.1 UniProtKB/TrEMBL
  ENSCAFT00000107507.1 UniProtKB/TrEMBL
  ENSCAFT00040000890.1 UniProtKB/TrEMBL
  ENSCAFT00845008865.1 UniProtKB/TrEMBL
  ENSCAFT00845008876 ENTREZGENE
  ENSCAFT00845008876.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1820 UniProtKB/TrEMBL
InterPro AB_hydrolase UniProtKB/TrEMBL
  Hydrolase_4 UniProtKB/TrEMBL
NCBI Gene ABHD17C ENTREZGENE
PANTHER ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN 17C UniProtKB/TrEMBL
Pfam Hydrolase_4 UniProtKB/TrEMBL
Superfamily-SCOP SSF53474 UniProtKB/TrEMBL
UniProt A0A8C0KP59 ENTREZGENE
  A0A8C0Q259 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MMS1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MW95_CANLF UniProtKB/TrEMBL
  A0A8P0PM00 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0PQC6_CANLF UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-01-12 ABHD17C  abhydrolase domain containing 17C, depalmitoylase  LOC488767  protein ABHD17C  Symbol and/or name change 5135510 APPROVED
2017-09-12 LOC488767  protein ABHD17C  ABHD17C  abhydrolase domain containing 17C  Symbol and/or name change 5135510 APPROVED