LOC489315 (olfactory receptor 8B12) - Rat Genome Database

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Gene: LOC489315 (olfactory receptor 8B12) Canis lupus familiaris
Analyze
Symbol: LOC489315
Name: olfactory receptor 8B12
RGD ID: 12188560
Description: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: MODEL
Previously known as: olfactory receptor 8B12-like; olfactory receptor family 8 subfamily B member 9B; OR8B9B
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.159,871,779 - 9,873,023 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha59,916,607 - 9,918,677 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.059,811,497 - 9,813,575 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.159,883,273 - 9,885,341 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.059,853,951 - 9,856,029 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.059,890,697 - 9,892,767 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Variants

.
Variants in LOC489315
12 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system exocrine system hepatobiliary system nervous system reproductive system respiratory system adipose tissue
High
Medium
Low 2
Below cutoff 5 1 1 4 3 3 3

Sequence


Reference Sequences
RefSeq Acc Id: XM_038477600   ⟹   XP_038333528
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.159,883,273 - 9,885,341 (+)NCBI
RefSeq Acc Id: XM_038503882   ⟹   XP_038359810
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha59,916,607 - 9,918,677 (+)NCBI
RefSeq Acc Id: XM_038535490   ⟹   XP_038391418
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.059,890,697 - 9,892,767 (+)NCBI
RefSeq Acc Id: XM_038599712   ⟹   XP_038455640
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.059,853,951 - 9,856,029 (+)NCBI
RefSeq Acc Id: XM_038664235   ⟹   XP_038520163
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.059,811,497 - 9,813,575 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_038333528   ⟸   XM_038477600
RefSeq Acc Id: XP_038455640   ⟸   XM_038599712
RefSeq Acc Id: XP_038520163   ⟸   XM_038664235
- UniProtKB: A0A8C0KFA3 (UniProtKB/TrEMBL),   A0A8C0M0V2 (UniProtKB/TrEMBL),   A0A8I3NIU4 (UniProtKB/TrEMBL),   A0A8C0N678 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038359810   ⟸   XM_038503882
- UniProtKB: A0A8C0N678 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038391418   ⟸   XM_038535490
- UniProtKB: A0A8C0N678 (UniProtKB/TrEMBL)
Protein Domains
G-protein coupled receptors family 1 profile


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00030000358 UniProtKB/TrEMBL
  ENSCAFG00030012966 UniProtKB/TrEMBL
  ENSCAFG00845011256 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00030000585.1 UniProtKB/TrEMBL
  ENSCAFT00030023942.1 UniProtKB/TrEMBL
  ENSCAFT00845019947 ENTREZGENE
  ENSCAFT00845019947.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
NCBI Gene LOC489315 ENTREZGENE
PANTHER G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A8C0KFA3 ENTREZGENE
  A0A8C0M0V2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0N678 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NIU4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-01-12 LOC489315  olfactory receptor 8B12  OR8B9B  olfactory receptor family 8 subfamily B member 9B  Symbol and/or name change 5135510 APPROVED
2020-11-24 OR8B9B  olfactory receptor family 8 subfamily B member 9B  LOC489315  olfactory receptor 8B12-like  Symbol and/or name change 5135510 APPROVED