NKX2-2 (NK2 homeobox 2) - Rat Genome Database

Name: NKX2-2
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

	Submit Data \| Help \| Video Tutorials \| News \| Publications \| FTP Download \| REST API \| Citing RGD \| Contact
	Search RGD Grant Resources Citing RGD About Us Contact Us Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References FTP Download Submit Data OntoMate (Literature Search) JBrowse (Genome Browser) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer ACP Haplotyper Genome Scanner Aging & Age-Related Disease Cancer Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease Find Models new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive Pathways Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
	Advanced Search (OLGA)

Gene: NKX2-2 (NK2 homeobox 2) Canis lupus familiaris

Analyze

Symbol:

NKX2-2

Name:

NK2 homeobox 2

RGD ID:

12188523

Description:

ENCODES a protein that exhibits cis-regulatory region sequence-specific DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN astrocyte differentiation (ortholog); cell development (ortholog); cell differentiation (ortholog); ASSOCIATED WITH demyelinating disease (ortholog); FOUND IN nucleus (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Also known as:

homeobox protein Nkx-2.2; NK2 transcription factor related, locus 2

RGD Orthologs

Human

Mouse

Rat

Chinchilla

Bonobo

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	NKX2-2 (NK2 homeobox 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Nkx2-2 (NK2 homeobox 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Nkx2-2 (NK2 homeobox 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Nkx2-2 (NK2 homeobox 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	NKX2-2 (NK2 homeobox 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Nkx2-2 (NK2 homeobox 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	NKX2-2 (NK2 homeobox 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):	NKX2-2 (NK2 homeobox 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Nkx2-2 (NK2 homeobox 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	24	1,925,013 - 1,935,874 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	24	1,933,176 - 1,935,875 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

demyelinating disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

astrocyte differentiation (IEA,ISO)

cell development (ISO)

cell differentiation (IBA,ISO)

digestive tract development (IEA,ISO)

endocrine pancreas development (ISO)

negative regulation of neuron differentiation (IEA,ISO)

nervous system development (ISO)

neuron fate specification (IEA,ISO)

oligodendrocyte development (IEA,ISO)

optic nerve development (ISO)

pancreatic A cell fate commitment (IEA,ISO)

pancreatic PP cell fate commitment (IEA,ISO)

positive regulation of cell differentiation (ISO)

positive regulation of gene expression (IEA,ISO)

positive regulation of neuron differentiation (IEA,ISO)

positive regulation of oligodendrocyte differentiation (IEA,ISO)

positive regulation of transcription by RNA polymerase II (IEA,ISO)

regulation of transcription by RNA polymerase II (IBA)

regulation of transcription, DNA-templated (ISO)

response to glucose (ISO)

response to organic cyclic compound (ISO)

response to progesterone (ISO)

smoothened signaling pathway (IEA,ISO)

spinal cord motor neuron differentiation (IEA,ISO)

spinal cord oligodendrocyte cell differentiation (ISO)

spinal cord oligodendrocyte cell fate specification (IEA,ISO)

type B pancreatic cell development (IEA,ISO)

type B pancreatic cell fate commitment (IEA,ISO)

ventral spinal cord interneuron fate determination (IEA,ISO)

Cellular Component

nucleus (IBA,IEA,ISO)

Molecular Function

cis-regulatory region sequence-specific DNA binding (IEA,ISO)

DNA-binding transcription activator activity, RNA polymerase II-specific (IEA,ISO)

DNA-binding transcription factor activity (ISO)

DNA-binding transcription factor activity, RNA polymerase II-specific (IBA)

protein binding (ISO)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (IBA,ISO)

sequence-specific DNA binding (ISO)

transcription factor binding (IEA,ISO)

References

Genomics

Comparative Map Data

NKX2-2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	24	1,925,013 - 1,935,874 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	24	1,933,176 - 1,935,875 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

NKX2-2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	20	21,511,017 - 21,514,064 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	20	21,511,010 - 21,514,064 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	20	21,491,655 - 21,494,702 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
GRCh37	20	21,491,655 - 21,494,664 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	20	21,439,648 - 21,442,664 (-)	NCBI	NCBI36		hg18	NCBI36
Build 34	20	21,439,653 - 21,442,664	NCBI
Celera	20	21,565,531 - 21,568,547 (-)	NCBI
Cytogenetic Map	20	p11.22	NCBI
HuRef	20	21,453,847 - 21,456,875 (-)	NCBI		HuRef
CHM1_1	20	21,491,637 - 21,494,646 (-)	NCBI		CHM1_1

Nkx2-2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	146,967,909 - 147,037,270 (-)	NCBI	GRCm39		mm39
GRCm38	2	147,176,485 - 147,195,434 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	147,177,546 - 147,194,243 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	147,003,282 - 147,012,138 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	2	146,874,593 - 146,877,800 (-)	NCBI			mm8
Celera	2	148,444,412 - 148,453,475 (-)	NCBI		Celera
Cytogenetic Map	2	G2	NCBI
cM Map	2	72.63	NCBI

Nkx2-2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	3	134,619,701 - 134,630,282 (-)	NCBI
Rnor_6.0 Ensembl	3	141,408,798 - 141,411,170 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	3	141,408,460 - 141,419,083 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	3	147,826,697 - 147,837,976 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	135,837,591 - 135,839,963 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	3	135,742,546 - 135,745,581 (-)	NCBI
Celera	3	133,482,823 - 133,485,195 (-)	NCBI		Celera
Cytogenetic Map	3	q41	NCBI

Nkx2-2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955415	29,258,434 - 29,268,259 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955415	29,263,741 - 29,268,259 (-)	NCBI	ChiLan1.0	ChiLan1.0

NKX2-2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	20	21,429,388 - 21,432,492 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	20	21,429,401 - 21,432,492 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	20	21,468,872 - 21,480,627 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

Nkx2-2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936620	3,961,106 - 3,962,910 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NKX2-2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	17	29,275,682 - 29,278,606 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	17	29,275,656 - 29,279,572 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	17	33,227,964 - 33,230,838 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NKX2-2
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	50,499,802 - 50,511,309 (-)	NCBI
ChlSab1.1 Ensembl	2	50,500,691 - 50,502,438 (-)	Ensembl

Nkx2-2
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624741	21,857,911 - 21,860,128 (-)	NCBI

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	reproductive system	respiratory system	adipose tissue
High
Medium			5						7		6
Low	5		6						5		4
Below cutoff		1	3	2	3	2	3	3		7		2

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_014107317	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038432954	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038432955	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038508167	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038508168	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038571422	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038571423	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038635657	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038635658	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_542867	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000024	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000260	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000063	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000376	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000024	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSCAFT00000008335 ⟹ ENSCAFP00000007724

RefSeq Status:

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	24	1,925,013 - 1,935,874 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00000078494 ⟹ ENSCAFP00000063267

RefSeq Status:

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	24	1,925,013 - 1,935,874 (+)	Ensembl

RefSeq Acc Id:

XM_014107317 ⟹ XP_013962792

RefSeq Status:

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	24	1,933,918 - 1,935,875 (+)	NCBI

Sequence:

show sequence

GCTCCGGGTAGCCCGGGTATAAATAGCTCACCCTGCCCCCTGCACGATCATAGAGGACGCTTTG
TGCGGGGCGGAGGGTGTCGAGAAAGTCCGAAAGCAAAAACGAAAGCCCCCAAAAAACCTGCCTT
AAATGGCCAAGCCGATCAATGCTGGGATTGTGGGGTTTTTCTTTTAAAAATCTGTCCACGTGCA
TCCGGAGAGGAAACTGCTTAAGGGGGCCAGAGCCCTTAACCCGCGAAGATCTTCTCCGCGCGCC
ACTCGCCCCAAATACGCACCCACACTTGCACGGGCTGGCGGCCGGCGCGGCGCCCCAGGACTCA
AGCTCCAAGTCCCCGGAGCCCTCGGCCGACGAGTCACCGGACAATGACAAGGAGACCCCGGGCG
GCGGGGGGGACGCGGGCAAGAAGCGGAAGCGGCGGGTGCTCTTCTCCAAGGCACAGACCTACGA
GCTGGAGCGGCGCTTCCGGCAGCAGCGGTACCTGTCGGCGCCCGAGCGCGAGCACCTGGCCAGC
CTCATCCGCCTCACGCCCACGCAGGTCAAGATCTGGTTCCAGAACCACCGCTACAAGATGAAGC
GCGCCCGGGCCGAGAAAGGTATGGAGGTGACGCCCCTACCCTCGCCGCGCCGGGTGGCCGTGCC
CGTTTTGGTCAGGGACGGCAAACCGTGCCATGCGCTCAAAGCCCAGGACCTGGCAGCCGCCACC
TTCCAGGCGGGCATCCCCTTTTCGGCCTACAGCGCGCAGTCTCTGCAGCACATGCAGTACAACG
CCCAGTACAGCTCGGCCAGCACCCCCCAGTACCCGACAGCACACCCCCTGGTCCAGGCCCAGCA
GTGGACTTGGTGAGCGCCGCCCCTCCGAGACTCGCGGCCCTAGGCCCAGGCCCCACCCCGGCGG
CGGCGGCGGACTCGGTCCTTTCGGTGGCTATTATTATTATTATAATTATTATTACGGAGTCGAG
TTGACTCTTGGCTCCTTTGGGGAGGCGCCGGGAGGTTGCCTGCGCCTCCCTGGAAGGGCAGATT
CCACCCACCCAGCTCTGCCCCTTTCCTCTCTCCTTTTGAACCTTTGGAGAGGGCTGAACTATAA
GCCGTGTTTACAGAATGTTTGCCTCTGGGGGGGTGGGGGGGGGACACCAAACCGTCCCCGCCTT
AACGTCCTCGCTTGAGACCGAGAAAAAGACCAACACACACACCCCGCCCCGCTTTTGTGAATTT
TGTAAAATATGTTTGTGTGATAGCGATATTGTCAGCCGTCTTCTAAAGCAAGTGGAGAACACTT
TAAAATTATAGAGAATTTTTCTCCTTTTTTTTTATAAGAAAATGCTAAATATTTATGGCCATGT
AAACGTTCTGACAACTGGTGACAGATTTCGCTCTTCGTTGTAAATATCGGTGGTGATTGTTGCC
AAAATGATCTTCAGTATGGGCCTGTACCCCCTGGGCCCGACTCCTTTCTTTGTGGTTTGTTTGC
GTTTGTTTATGTTTGGTTACCCCCTGCTTTCTTTTCCTTTTATATTTTGTTCAGTGCAAACATT
TCTCAAATATGAAAAAGGAAAAAATGTGTAGGCGAGAAGCCCCCTGCCCCATCTCCGGGTCCTG
AGCCCGGGGACTTGGAGCTCAGCGGTTCCGTGCGGGTCCCCAAGAGCGCCGGACGCTGAAAGCT
TTCGATTTTTTAAATAAGAATTTTAATAAAAATCCTGTGTTTAAAAAAACCAA

hide sequence

RefSeq Acc Id:

XM_542867 ⟹ XP_542867

RefSeq Status:

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	24	1,933,176 - 1,935,875 (+)	NCBI

Sequence:

show sequence

CCTCCCCCCCATACCCCCTCCCCGCCCCAACTGGGGAGCGCCGCGAATTGACCAAGTGAAGCTA
CAACTTTGCGGCATAAATTGCGGGGTCCCGAGCCATGTCGCTGACCAACACAAAGACGGGGTTT
TCGGTCAAGGACATCTTGGACCTGCCGGACACCAACGACGAGGAAGGCTCGGTGGCTGAAGGGC
CGGAGGAGGAGAGCGAGGGCCCCGAGCCCGCCAAGAGGGCCGGGCCGCTGGGGCAGGGCGCCCT
GGACGCGGTGCAGAGCCTGCCCCTGAAGAACCCCTTCTACGACAGCAGCGACAACCCATATACG
CGCTGGCTGGCCAGCACCGAGGGCCTCCAGTACTCCCTGCACGGGCTGGCGGCCGGCGCGGCGC
CCCAGGACTCAAGCTCCAAGTCCCCGGAGCCCTCGGCCGACGAGTCACCGGACAATGACAAGGA
GACCCCGGGCGGCGGGGGGGACGCGGGCAAGAAGCGGAAGCGGCGGGTGCTCTTCTCCAAGGCA
CAGACCTACGAGCTGGAGCGGCGCTTCCGGCAGCAGCGGTACCTGTCGGCGCCCGAGCGCGAGC
ACCTGGCCAGCCTCATCCGCCTCACGCCCACGCAGGTCAAGATCTGGTTCCAGAACCACCGCTA
CAAGATGAAGCGCGCCCGGGCCGAGAAAGGTATGGAGGTGACGCCCCTACCCTCGCCGCGCCGG
GTGGCCGTGCCCGTTTTGGTCAGGGACGGCAAACCGTGCCATGCGCTCAAAGCCCAGGACCTGG
CAGCCGCCACCTTCCAGGCGGGCATCCCCTTTTCGGCCTACAGCGCGCAGTCTCTGCAGCACAT
GCAGTACAACGCCCAGTACAGCTCGGCCAGCACCCCCCAGTACCCGACAGCACACCCCCTGGTC
CAGGCCCAGCAGTGGACTTGGTGAGCGCCGCCCCTCCGAGACTCGCGGCCCTAGGCCCAGGCCC
CACCCCGGCGGCGGCGGCGGACTCGGTCCTTTCGGTGGCTATTATTATTATTATAATTATTATT
ACGGAGTCGAGTTGACTCTTGGCTCCTTTGGGGAGGCGCCGGGAGGTTGCCTGCGCCTCCCTGG
AAGGGCAGATTCCACCCACCCAGCTCTGCCCCTTTCCTCTCTCCTTTTGAACCTTTGGAGAGGG
CTGAACTATAAGCCGTGTTTACAGAATGTTTGCCTCTGGGGGGGTGGGGGGGGGACACCAAACC
GTCCCCGCCTTAACGTCCTCGCTTGAGACCGAGAAAAAGACCAACACACACACCCCGCCCCGCT
TTTGTGAATTTTGTAAAATATGTTTGTGTGATAGCGATATTGTCAGCCGTCTTCTAAAGCAAGT
GGAGAACACTTTAAAATTATAGAGAATTTTTCTCCTTTTTTTTTATAAGAAAATGCTAAATATT
TATGGCCATGTAAACGTTCTGACAACTGGTGACAGATTTCGCTCTTCGTTGTAAATATCGGTGG
TGATTGTTGCCAAAATGATCTTCAGTATGGGCCTGTACCCCCTGGGCCCGACTCCTTTCTTTGT
GGTTTGTTTGCGTTTGTTTATGTTTGGTTACCCCCTGCTTTCTTTTCCTTTTATATTTTGTTCA
GTGCAAACATTTCTCAAATATGAAAAAGGAAAAAATGTGTAGGCGAGAAGCCCCCTGCCCCATC
TCCGGGTCCTGAGCCCGGGGACTTGGAGCTCAGCGGTTCCGTGCGGGTCCCCAAGAGCGCCGGA
CGCTGAAAGCTTTCGATTTTTTAAATAAGAATTTTAATAAAAATCCTGTGTTTAAAAAAACCAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_013962792	(Get FASTA)	NCBI Sequence Viewer
	XP_038288882	(Get FASTA)	NCBI Sequence Viewer
	XP_038288883	(Get FASTA)	NCBI Sequence Viewer
	XP_038364095	(Get FASTA)	NCBI Sequence Viewer
	XP_038364096	(Get FASTA)	NCBI Sequence Viewer
	XP_038427350	(Get FASTA)	NCBI Sequence Viewer
	XP_038427351	(Get FASTA)	NCBI Sequence Viewer
	XP_038491585	(Get FASTA)	NCBI Sequence Viewer
	XP_038491586	(Get FASTA)	NCBI Sequence Viewer
	XP_542867	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	XP_542867 ⟸ XM_542867
- Peptide Label:	isoform X1
- UniProtKB:	E2RNP4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSLTNTKTGFSVKDILDLPDTNDEEGSVAEGPEEESEGPEPAKRAGPLGQGALDAVQSLPLKNP FYDSSDNPYTRWLASTEGLQYSLHGLAAGAAPQDSSSKSPEPSADESPDNDKETPGGGGDAGKK RKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKMKRARAEKGM EVTPLPSPRRVAVPVLVRDGKPCHALKAQDLAAATFQAGIPFSAYSAQSLQHMQYNAQYSSAST PQYPTAHPLVQAQQWTW hide sequence

RefSeq Acc Id:

XP_013962792 ⟸ XM_014107317

- Peptide Label:

isoform X2

- Sequence:

show sequence

MLGLWGFSFKNLSTCIRRGNCLRGPEPLTREDLLRAPLAPNTHPHLHGLAAGAAPQDSSSKSPE
PSADESPDNDKETPGGGGDAGKKRKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLTP
TQVKIWFQNHRYKMKRARAEKGMEVTPLPSPRRVAVPVLVRDGKPCHALKAQDLAAATFQAGIP
FSAYSAQSLQHMQYNAQYSSASTPQYPTAHPLVQAQQWTW

hide sequence

RefSeq Acc Id:

ENSCAFP00000063267 ⟸ ENSCAFT00000078494

RefSeq Acc Id:

ENSCAFP00000007724 ⟸ ENSCAFT00000008335

Protein Domains

Homeobox

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000005173	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSCAFP00000007724	ENTREZGENE, UniProtKB/TrEMBL
	ENSCAFP00000063267	UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000008335	UniProtKB/TrEMBL
	ENSCAFT00000078494	UniProtKB/TrEMBL
InterPro	Homeobox-like	UniProtKB/TrEMBL
	Homeobox_CS	UniProtKB/TrEMBL
	Homeobox_dom	UniProtKB/TrEMBL
	Homeobox_metazoa	UniProtKB/TrEMBL
NCBI Gene	NKX2-2	ENTREZGENE
Pfam	Homeobox	UniProtKB/TrEMBL
PRINTS	HOMEOBOX	UniProtKB/TrEMBL
PROSITE	HOMEOBOX_1	UniProtKB/TrEMBL
	HOMEOBOX_2	UniProtKB/TrEMBL
SMART	HOX	UniProtKB/TrEMBL
Superfamily-SCOP	SSF46689	UniProtKB/TrEMBL
UniProt	A0A5F4D951_CANLF	UniProtKB/TrEMBL
	E2RNP4	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:43833	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)