LGALS1 (galectin 1) - Rat Genome Database

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Gene: LGALS1 (galectin 1) Canis lupus familiaris
Analyze
Symbol: LGALS1
Name: galectin 1
RGD ID: 12188220
Description: ENCODES a protein that exhibits identical protein binding (ortholog); lactose binding (ortholog); laminin binding (ortholog); INVOLVED IN cell-cell adhesion (ortholog); cellular response to glucose stimulus (ortholog); maintenance of protein location (ortholog); ASSOCIATED WITH B-cell lymphoma (ortholog); COVID-19 (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN cell surface (ortholog); cytosol (ortholog); extracellular space (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: galectin-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11026,932,351 - 26,935,580 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1026,932,301 - 26,935,646 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1026,887,006 - 26,890,237 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01027,724,227 - 27,727,457 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1027,724,177 - 27,727,523 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11027,446,500 - 27,449,728 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01027,755,263 - 27,758,492 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01027,932,614 - 27,935,843 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21127048   PMID:22301074   PMID:24778023   PMID:26589652   PMID:30032202  


Genomics

Comparative Map Data
LGALS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11026,932,351 - 26,935,580 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1026,932,301 - 26,935,646 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1026,887,006 - 26,890,237 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01027,724,227 - 27,727,457 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1027,724,177 - 27,727,523 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11027,446,500 - 27,449,728 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01027,755,263 - 27,758,492 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01027,932,614 - 27,935,843 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
LGALS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382237,675,636 - 37,679,802 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2237,675,636 - 37,679,805 (+)Ensemblhg38GRCh38
GRCh372238,071,643 - 38,075,809 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362236,401,559 - 36,405,755 (+)NCBIBuild 36Build 36hg18NCBI36
Build 342236,396,142 - 36,400,307NCBI
Celera2221,873,464 - 21,877,660 (+)NCBICelera
Cytogenetic Map22q13.1NCBI
HuRef2221,038,558 - 21,042,751 (+)NCBIHuRef
CHM1_12238,030,320 - 38,034,516 (+)NCBICHM1_1
T2T-CHM13v2.02238,136,888 - 38,141,054 (+)NCBIT2T-CHM13v2.0
Lgals1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391578,810,925 - 78,814,665 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1578,810,925 - 78,814,665 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381578,926,725 - 78,930,465 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1578,926,725 - 78,930,465 (+)Ensemblmm10GRCm38
MGSCv371578,757,155 - 78,760,895 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361578,753,980 - 78,757,720 (+)NCBIMGSCv36mm8
MGSCv361579,650,845 - 79,654,585 (+)NCBIMGSCv36mm8
Cytogenetic Map15E1NCBI
cM Map1537.7NCBI
Lgals1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87112,365,695 - 112,368,801 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl7112,361,850 - 112,368,800 (+)EnsemblGRCr8
mRatBN7.27110,485,239 - 110,488,345 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7110,481,392 - 110,488,345 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx7112,234,764 - 112,237,858 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07114,458,284 - 114,461,378 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07114,426,881 - 114,429,988 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.07120,153,184 - 120,156,290 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7120,153,184 - 120,156,289 (+)Ensemblrn6Rnor6.0
Rnor_5.07120,144,875 - 120,147,981 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.47116,893,662 - 116,896,768 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera7106,819,373 - 106,822,479 (+)NCBICelera
RGSC_v3.17116,927,891 - 116,930,997 (+)NCBI
Cytogenetic Map7q34NCBI
Lgals1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541324,072,086 - 24,075,452 (+)Ensembl
ChiLan1.0NW_00495541324,072,086 - 24,075,452 (+)NCBIChiLan1.0ChiLan1.0
LGALS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22347,535,718 - 47,539,994 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12250,224,324 - 50,228,602 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02218,593,154 - 18,597,432 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12236,426,226 - 36,430,356 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2236,426,228 - 36,430,356 (+)EnsemblpanPan2panpan1.1
Lgals1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494510,397,291 - 10,400,438 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364923,407,049 - 3,411,222 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364923,407,704 - 3,411,197 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LGALS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl510,149,068 - 10,156,023 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1510,149,069 - 10,152,514 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.257,642,321 - 7,645,763 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LGALS1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11920,379,144 - 20,383,303 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1920,379,003 - 20,383,464 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666045105,440,547 - 105,444,741 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lgals1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475210,219,872 - 10,223,317 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462475210,220,115 - 10,223,434 (-)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in LGALS1
22 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000002307   ⟹   ENSCAFP00000002130
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1026,932,301 - 26,935,084 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000048962   ⟹   ENSCAFP00000041023
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1026,932,301 - 26,934,530 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000060929   ⟹   ENSCAFP00000043305
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1026,932,302 - 26,935,646 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845010422   ⟹   ENSCAFP00845008099
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1027,724,177 - 27,726,961 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845010429   ⟹   ENSCAFP00845008105
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1027,724,177 - 27,726,407 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845010440   ⟹   ENSCAFP00845008114
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1027,724,177 - 27,726,111 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845010453   ⟹   ENSCAFP00845008124
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1027,724,178 - 27,727,523 (-)Ensembl
RefSeq Acc Id: NM_001201488   ⟹   NP_001188417
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11026,932,351 - 26,935,580 (-)NCBI
Dog10K_Boxer_Tasha1026,887,006 - 26,890,237 (-)NCBI
ROS_Cfam_1.01027,724,227 - 27,727,457 (-)NCBI
UMICH_Zoey_3.11027,446,500 - 27,449,728 (-)NCBI
UNSW_CanFamBas_1.01027,755,263 - 27,758,492 (-)NCBI
UU_Cfam_GSD_1.01027,932,614 - 27,935,843 (-)NCBI
Sequence:
RefSeq Acc Id: NP_001188417   ⟸   NM_001201488
- UniProtKB: A0A5F4BNM9 (UniProtKB/TrEMBL),   A0A8C0JR26 (UniProtKB/TrEMBL),   A0A8P0SWK0 (UniProtKB/TrEMBL),   A0A8I3N184 (UniProtKB/TrEMBL),   A0A8P0N4M2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000043305   ⟸   ENSCAFT00000060929
Ensembl Acc Id: ENSCAFP00000041023   ⟸   ENSCAFT00000048962
Ensembl Acc Id: ENSCAFP00000002130   ⟸   ENSCAFT00000002307
Ensembl Acc Id: ENSCAFP00845008105   ⟸   ENSCAFT00845010429
Ensembl Acc Id: ENSCAFP00845008114   ⟸   ENSCAFT00845010440
Ensembl Acc Id: ENSCAFP00845008124   ⟸   ENSCAFT00845010453
Ensembl Acc Id: ENSCAFP00845008099   ⟸   ENSCAFT00845010422
Protein Domains
Galectin

Promoters
RGD ID:13684980
Promoter ID:EPDNEW_C3050
Type:multiple initiation site
Name:LGALS1_1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11026,935,642 - 26,935,702EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000001487 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00845005881 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000002307.5 UniProtKB/TrEMBL
  ENSCAFT00000048962.4 UniProtKB/TrEMBL
  ENSCAFT00000060929.2 UniProtKB/TrEMBL
  ENSCAFT00000095423.1 UniProtKB/TrEMBL
  ENSCAFT00845010422.1 UniProtKB/TrEMBL
  ENSCAFT00845010429.1 UniProtKB/TrEMBL
  ENSCAFT00845010440.1 UniProtKB/TrEMBL
  ENSCAFT00845010453 ENTREZGENE
  ENSCAFT00845010453.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.200 UniProtKB/TrEMBL
InterPro ConA-like_dom_sf UniProtKB/TrEMBL
  Galectin-like UniProtKB/TrEMBL
  Galectin_CRD UniProtKB/TrEMBL
KEGG Report cfa:610276 UniProtKB/TrEMBL
NCBI Gene LGALS1 ENTREZGENE
PANTHER GALECTIN-1 UniProtKB/TrEMBL
  PTHR11346 UniProtKB/TrEMBL
Pfam Gal-bind_lectin UniProtKB/TrEMBL
PROSITE GALECTIN UniProtKB/TrEMBL
SMART Gal-bind_lectin UniProtKB/TrEMBL
  GLECT UniProtKB/TrEMBL
Superfamily-SCOP SSF49899 UniProtKB/TrEMBL
UniProt A0A5F4BNM9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0JR26 ENTREZGENE
  A0A8I3MSR8_CANLF UniProtKB/TrEMBL
  A0A8I3MVF5_CANLF UniProtKB/TrEMBL
  A0A8I3N184 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0N4M2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0SV03_CANLF UniProtKB/TrEMBL
  A0A8P0SWK0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0TJS9_CANLF UniProtKB/TrEMBL