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Gene: CYP46A1 (cytochrome P450 family 46 subfamily A member 1) Canis lupus familiaris
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Symbol: CYP46A1
Name: cytochrome P450 family 46 subfamily A member 1
Description: ENCODES a protein that exhibits iron ion binding (inferred); steroid hydroxylase activity (inferred); INVOLVED IN protein localization to membrane raft (ortholog); PARTICIPATES IN bile acid biosynthetic pathway; cerebrotendinous xanthomatosis pathway; congenital bile acid synthesis defect pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); FOUND IN dendrite (inferred); endoplasmic reticulum membrane (inferred); postsynapse (inferred)
Type: protein-coding
RefSeq Status: MODEL
Also known as: cholesterol 24-hydroxylase; cytochrome P450, family 46, subfamily A, polypeptide 1
Orthologs:
Homo sapiens (human) : CYP46A1 (cytochrome P450 family 46 subfamily A member 1)  HGNC  Alliance
Mus musculus (house mouse) : Cyp46a1 (cytochrome P450, family 46, subfamily a, polypeptide 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cyp46a1 (cytochrome P450, family 46, subfamily a, polypeptide 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : LOC102030124 (cholesterol 24-hydroxylase)
Pan paniscus (bonobo/pygmy chimpanzee) : CYP46A1 (cytochrome P450 family 46 subfamily A member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101961079 (cholesterol 24-hydroxylase)
Sus scrofa (pig) : LOC100512793 (cholesterol 24-hydroxylase)
Chlorocebus sabaeus (African green monkey) : CYP46A1 (cytochrome P450 family 46 subfamily A member 1)
Heterocephalus glaber (naked mole-rat) : LOC101708822 (cholesterol 24-hydroxylase)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl868,041,344 - 68,095,212 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1868,064,898 - 68,095,537 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)
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Expression

RNA-SEQ Expression

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Nucleotide Sequences
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Nomenclature History
 
More on CYP46A1
NCBI Gene
Ensembl Gene
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RGD Object Information
RGD ID: 12186203
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2020-07-01
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.