MIR486 (microRNA mir-486) - Rat Genome Database

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Gene: MIR486 (microRNA mir-486) Canis lupus familiaris
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Symbol: MIR486 (Ensembl: MIR486-1)
Name: microRNA mir-486 (Ensembl:microRNA 486-1)
RGD ID: 12184918
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: cfa-mir-486; microRNA 486
RGD Orthologs
Human
Mouse
Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11623,958,963 - 23,959,026 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1623,958,963 - 23,959,026 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1624,463,727 - 24,463,790 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01625,706,837 - 25,706,900 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1625,706,837 - 25,706,900 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11624,078,703 - 24,078,766 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01624,640,650 - 24,640,713 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01624,691,913 - 24,691,976 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:16381832   PMID:18392026   PMID:24692655  


Genomics

Comparative Map Data
MIR486
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11623,958,963 - 23,959,026 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1623,958,963 - 23,959,026 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1624,463,727 - 24,463,790 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01625,706,837 - 25,706,900 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1625,706,837 - 25,706,900 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11624,078,703 - 24,078,766 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01624,640,650 - 24,640,713 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01624,691,913 - 24,691,976 (-)NCBIUU_Cfam_GSD_1.0
MIR486-1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38841,660,441 - 41,660,508 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl841,660,441 - 41,660,508 (-)EnsemblGRCh38hg38GRCh38
GRCh37841,517,959 - 41,518,026 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36841,637,115 - 41,637,182 (-)NCBINCBI36Build 36hg18NCBI36
Celera840,466,482 - 40,466,549 (-)NCBICelera
Cytogenetic Map8p11.21NCBI
HuRef840,045,689 - 40,045,756 (-)NCBIHuRef
CHM1_1841,566,127 - 41,566,194 (-)NCBICHM1_1
T2T-CHM13v2.0841,934,039 - 41,934,106 (-)NCBIT2T-CHM13v2.0
Mir486
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39823,632,571 - 23,632,698 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl823,632,571 - 23,632,698 (+)EnsemblGRCm39 Ensembl
GRCm38823,142,555 - 23,142,682 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl823,142,555 - 23,142,682 (+)EnsemblGRCm38mm10GRCm38
MGSCv37824,253,027 - 24,253,154 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera824,638,894 - 24,638,926 (+)NCBICelera
Cytogenetic Map8A2NCBI
cM Map811.42NCBI
Mir486
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0 Ensembl1673,680,363 - 73,680,490 (-)EnsemblRnor6.0rn6Rnor6.0

Variants

.
Variants in MIR486
1 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

circulatory system endocrine system integumental system musculoskeletal system nervous system reproductive system respiratory system
High
Medium
Low 5 5 1 3 5 1 1
Below cutoff 2 2 3 2 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000040855
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1623,958,963 - 23,959,026 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845014759
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1625,706,837 - 25,706,900 (-)Ensembl
RefSeq Acc Id: NR_128722
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11623,958,963 - 23,959,026 (-)NCBI
Dog10K_Boxer_Tasha1624,463,727 - 24,463,790 (-)NCBI
ROS_Cfam_1.01625,706,837 - 25,706,900 (-)NCBI
UMICH_Zoey_3.11624,078,703 - 24,078,766 (-)NCBI
UNSW_CanFamBas_1.01624,640,650 - 24,640,713 (-)NCBI
UU_Cfam_GSD_1.01624,691,913 - 24,691,976 (-)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000026572 Ensembl
  ENSCAFG00845008401 Ensembl, ENTREZGENE
Ensembl Transcript ENSCAFT00845014759 ENTREZGENE
miRBase MI0008027 ENTREZGENE
NCBI Gene MIR486 ENTREZGENE
RNAcentral URS00007E34BA RNACentral
  URS00007E3CD2 RNACentral
  URS00007E492E RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-02 MIR486  microRNA mir-486    microRNA 486  Symbol and/or name change 5135510 APPROVED