BLM (BLM RecQ like helicase) - Rat Genome Database

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Gene: BLM (BLM RecQ like helicase) Canis lupus familiaris
Analyze
Symbol: BLM
Name: BLM RecQ like helicase
RGD ID: 12183987
Description: ENCODES a protein that exhibits 3'-5' DNA helicase activity (inferred); 8-hydroxy-2'-deoxyguanosine DNA binding (inferred); ATP binding (inferred); INVOLVED IN alpha-beta T cell differentiation (ortholog); alpha-beta T cell proliferation (ortholog); cellular response to xenobiotic stimulus (ortholog); PARTICIPATES IN DNA replication pathway; homologous recombination pathway of double-strand break repair; ASSOCIATED WITH Bloom syndrome (ortholog); Breast Cancer, Familial (ortholog); colorectal cancer (ortholog); FOUND IN male germ cell nucleus (ortholog); pronucleus (ortholog); RecQ family helicase-topoisomerase III complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Bloom syndrome protein-like; Bloom syndrome RecQ like helicase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1353,408,120 - 53,506,728 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl353,408,217 - 53,473,146 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha356,045,661 - 56,144,322 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0353,824,072 - 53,922,767 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl353,824,080 - 53,922,707 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1353,343,266 - 53,441,845 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0353,555,047 - 53,653,568 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0353,894,900 - 53,993,588 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
alpha-beta T cell differentiation  (ISO)
alpha-beta T cell proliferation  (ISO)
cellular response to camptothecin  (IEA)
cellular response to hydroxyurea  (IEA)
cellular response to ionizing radiation  (IEA)
cellular response to xenobiotic stimulus  (ISO)
chromosome organization  (ISO)
DN4 thymocyte differentiation  (ISO)
DNA damage response  (IEA)
DNA double-strand break processing  (IEA)
DNA duplex unwinding  (IEA)
DNA metabolic process  (IEA)
DNA recombination  (IEA)
DNA repair  (IEA,ISO)
DNA replication  (IEA)
DNA unwinding involved in DNA replication  (IEA)
double-strand break repair via homologous recombination  (IEA)
G-quadruplex DNA unwinding  (IEA)
immature T cell proliferation in thymus  (ISO)
mitotic G2 DNA damage checkpoint signaling  (IEA)
mitotic recombination  (ISO)
negative regulation of cell division  (IEA)
negative regulation of DNA recombination  (IEA)
negative regulation of mitotic recombination  (ISO)
negative regulation of thymocyte apoptotic process  (ISO)
positive regulation of alpha-beta T cell proliferation  (ISO)
positive regulation of DNA-templated transcription  (IEA)
positive regulation of double-strand break repair via homologous recombination  (ISO)
positive regulation of immature T cell proliferation in thymus  (ISO)
protein complex oligomerization  (IEA)
protein homooligomerization  (IEA)
regulation of DNA-templated DNA replication  (IEA)
replication fork processing  (IEA)
replication-born double-strand break repair via sister chromatid exchange  (ISO)
resolution of DNA recombination intermediates  (IEA)
response to X-ray  (IEA)
telomere maintenance  (IEA,ISO)
telomeric D-loop disassembly  (IEA)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
BLM
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1353,408,120 - 53,506,728 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl353,408,217 - 53,473,146 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha356,045,661 - 56,144,322 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0353,824,072 - 53,922,767 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl353,824,080 - 53,922,707 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1353,343,266 - 53,441,845 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0353,555,047 - 53,653,568 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0353,894,900 - 53,993,588 (-)NCBIUU_Cfam_GSD_1.0
BLM
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381590,717,346 - 90,816,166 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1590,717,346 - 90,816,166 (+)EnsemblGRCh38hg38GRCh38
GRCh371591,260,577 - 91,359,396 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361589,061,583 - 89,159,690 (+)NCBINCBI36Build 36hg18NCBI36
Build 341589,061,605 - 89,159,601NCBI
Celera1567,669,191 - 67,767,281 (+)NCBICelera
Cytogenetic Map15q26.1NCBI
HuRef1567,371,963 - 67,470,518 (+)NCBIHuRef
CHM1_11591,102,306 - 91,200,343 (+)NCBICHM1_1
T2T-CHM13v2.01588,475,676 - 88,575,539 (+)NCBIT2T-CHM13v2.0
Blm
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39780,104,839 - 80,184,896 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl780,104,481 - 80,184,867 (-)EnsemblGRCm39 Ensembl
GRCm38780,454,993 - 80,535,148 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl780,454,733 - 80,535,119 (-)EnsemblGRCm38mm10GRCm38
MGSCv37787,599,879 - 87,680,005 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36780,328,605 - 80,408,501 (-)NCBIMGSCv36mm8
Celera777,855,450 - 77,935,749 (-)NCBICelera
Cytogenetic Map7D2NCBI
cM Map745.65NCBI
Blm
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81143,819,072 - 143,905,300 (-)NCBIGRCr8
mRatBN7.21134,409,832 - 134,496,073 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1134,409,857 - 134,484,312 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01142,246,773 - 142,332,616 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1142,246,790 - 142,332,588 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01143,198,619 - 143,285,603 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41136,271,573 - 136,358,077 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11136,350,811 - 136,606,090 (-)NCBI
Celera1126,469,103 - 126,554,926 (-)NCBICelera
Cytogenetic Map1q31NCBI
Blm
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541614,842,033 - 14,899,687 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541614,814,753 - 14,899,865 (+)NCBIChiLan1.0ChiLan1.0
BLM
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21680,267,894 - 80,368,918 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11583,965,915 - 84,066,920 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01569,407,248 - 69,508,070 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11588,607,157 - 88,707,864 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1588,607,157 - 88,707,864 (+)Ensemblpanpan1.1panPan2
Blm
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640130,038,668 - 130,140,428 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648316,194,092 - 16,255,905 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648316,194,092 - 16,295,803 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BLM
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl753,317,540 - 53,412,645 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1753,317,515 - 53,412,649 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2758,374,719 - 58,443,673 (+)NCBISscrofa10.2Sscrofa10.2susScr3
BLM
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1299,046,485 - 9,152,320 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl299,045,373 - 9,152,254 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605937,540,996 - 37,654,124 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Blm
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476817,421,291 - 17,522,799 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476817,422,267 - 17,522,894 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in BLM
749 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium
Low 5 5 16 6 6 12 8 10 5
Below cutoff 6 6 6 6 1

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003434379 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_014112442 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022416949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022416951 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022416952 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038471951 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038471952 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038471953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038471954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038471955 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038475672 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038532885 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038532886 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038532887 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038532888 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038532889 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038597210 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038597211 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038597212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038597213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038597214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038661391 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038661392 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038661393 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038661394 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038661396 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000074 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSCAFT00000019677   ⟹   ENSCAFP00000018251
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl353,408,217 - 53,473,146 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000042800   ⟹   ENSCAFP00000043065
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl353,408,217 - 53,473,146 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000072655   ⟹   ENSCAFP00000048409
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl353,408,217 - 53,473,146 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845004298   ⟹   ENSCAFP00845003429
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl353,824,080 - 53,922,707 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845004310   ⟹   ENSCAFP00845003440
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl353,824,080 - 53,922,707 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845004360   ⟹   ENSCAFP00845003482
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl353,824,080 - 53,922,707 (-)Ensembl
RefSeq Acc Id: XM_003434379   ⟹   XP_003434427
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1353,408,120 - 53,506,728 (-)NCBI
Dog10K_Boxer_Tasha356,045,661 - 56,144,322 (-)NCBI
Sequence:
RefSeq Acc Id: XM_014112442   ⟹   XP_013967917
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1353,408,120 - 53,466,851 (-)NCBI
Dog10K_Boxer_Tasha356,045,661 - 56,104,426 (-)NCBI
Sequence:
RefSeq Acc Id: XM_022416949   ⟹   XP_022272657
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1353,408,120 - 53,506,728 (-)NCBI
Dog10K_Boxer_Tasha356,045,661 - 56,144,322 (-)NCBI
Sequence:
RefSeq Acc Id: XM_022416951   ⟹   XP_022272659
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1353,408,120 - 53,506,728 (-)NCBI
Dog10K_Boxer_Tasha356,045,661 - 56,144,322 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038471951   ⟹   XP_038327879
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1353,343,266 - 53,441,845 (-)NCBI
RefSeq Acc Id: XM_038471952   ⟹   XP_038327880
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1353,343,266 - 53,441,845 (-)NCBI
RefSeq Acc Id: XM_038471953   ⟹   XP_038327881
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1353,343,266 - 53,441,845 (-)NCBI
RefSeq Acc Id: XM_038471954   ⟹   XP_038327882
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1353,343,266 - 53,405,107 (-)NCBI
RefSeq Acc Id: XM_038471955   ⟹   XP_038327883
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1353,343,266 - 53,401,985 (-)NCBI
RefSeq Acc Id: XM_038475672   ⟹   XP_038331600
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha356,045,661 - 56,107,556 (-)NCBI
RefSeq Acc Id: XM_038532885   ⟹   XP_038388813
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0353,894,900 - 53,993,588 (-)NCBI
RefSeq Acc Id: XM_038532886   ⟹   XP_038388814
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0353,894,900 - 53,993,588 (-)NCBI
RefSeq Acc Id: XM_038532887   ⟹   XP_038388815
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0353,894,900 - 53,993,588 (-)NCBI
RefSeq Acc Id: XM_038532888   ⟹   XP_038388816
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0353,894,900 - 53,956,813 (-)NCBI
RefSeq Acc Id: XM_038532889   ⟹   XP_038388817
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0353,894,900 - 53,953,683 (-)NCBI
RefSeq Acc Id: XM_038597210   ⟹   XP_038453138
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0353,555,047 - 53,653,568 (-)NCBI
RefSeq Acc Id: XM_038597211   ⟹   XP_038453139
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0353,555,047 - 53,653,568 (-)NCBI
RefSeq Acc Id: XM_038597212   ⟹   XP_038453140
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0353,555,047 - 53,653,568 (-)NCBI
RefSeq Acc Id: XM_038597213   ⟹   XP_038453141
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0353,555,047 - 53,616,890 (-)NCBI
RefSeq Acc Id: XM_038597214   ⟹   XP_038453142
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0353,555,047 - 53,613,761 (-)NCBI
RefSeq Acc Id: XM_038661391   ⟹   XP_038517319
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0353,824,072 - 53,922,767 (-)NCBI
RefSeq Acc Id: XM_038661392   ⟹   XP_038517320
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0353,824,072 - 53,922,767 (-)NCBI
RefSeq Acc Id: XM_038661393   ⟹   XP_038517321
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0353,824,072 - 53,922,767 (-)NCBI
RefSeq Acc Id: XM_038661394   ⟹   XP_038517322
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0353,824,072 - 53,885,993 (-)NCBI
RefSeq Acc Id: XM_038661396   ⟹   XP_038517324
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0353,824,072 - 53,882,863 (-)NCBI
Protein Sequences
Protein RefSeqs XP_003434427 (Get FASTA)   NCBI Sequence Viewer  
  XP_013967917 (Get FASTA)   NCBI Sequence Viewer  
  XP_022272657 (Get FASTA)   NCBI Sequence Viewer  
  XP_022272659 (Get FASTA)   NCBI Sequence Viewer  
  XP_038327879 (Get FASTA)   NCBI Sequence Viewer  
  XP_038327880 (Get FASTA)   NCBI Sequence Viewer  
  XP_038327881 (Get FASTA)   NCBI Sequence Viewer  
  XP_038327882 (Get FASTA)   NCBI Sequence Viewer  
  XP_038327883 (Get FASTA)   NCBI Sequence Viewer  
  XP_038331600 (Get FASTA)   NCBI Sequence Viewer  
  XP_038388813 (Get FASTA)   NCBI Sequence Viewer  
  XP_038388814 (Get FASTA)   NCBI Sequence Viewer  
  XP_038388815 (Get FASTA)   NCBI Sequence Viewer  
  XP_038388816 (Get FASTA)   NCBI Sequence Viewer  
  XP_038388817 (Get FASTA)   NCBI Sequence Viewer  
  XP_038453138 (Get FASTA)   NCBI Sequence Viewer  
  XP_038453139 (Get FASTA)   NCBI Sequence Viewer  
  XP_038453140 (Get FASTA)   NCBI Sequence Viewer  
  XP_038453141 (Get FASTA)   NCBI Sequence Viewer  
  XP_038453142 (Get FASTA)   NCBI Sequence Viewer  
  XP_038517319 (Get FASTA)   NCBI Sequence Viewer  
  XP_038517320 (Get FASTA)   NCBI Sequence Viewer  
  XP_038517321 (Get FASTA)   NCBI Sequence Viewer  
  XP_038517322 (Get FASTA)   NCBI Sequence Viewer  
  XP_038517324 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCAFP00000018251.4
  ENSCAFP00000043065.2
  ENSCAFP00000048409.1
  ENSCAFP00030002717.1
  ENSCAFP00040004735.1
  ENSCAFP00040004760.1
  ENSCAFP00040004796.1
  ENSCAFP00845003429
  ENSCAFP00845003429.1
  ENSCAFP00845003440
  ENSCAFP00845003440.1
  ENSCAFP00845003482.1
RefSeq Acc Id: XP_003434427   ⟸   XM_003434379
- Peptide Label: isoform X2
- UniProtKB: A0A8C0RAG2 (UniProtKB/TrEMBL),   A0A8I3MFB9 (UniProtKB/TrEMBL),   A0A8C0KUW7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013967917   ⟸   XM_014112442
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_022272659   ⟸   XM_022416951
- Peptide Label: isoform X3
- UniProtKB: A0A8I3MT50 (UniProtKB/TrEMBL),   A0A8P0SWG9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022272657   ⟸   XM_022416949
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KUW7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000018251   ⟸   ENSCAFT00000019677
RefSeq Acc Id: ENSCAFP00000043065   ⟸   ENSCAFT00000042800
RefSeq Acc Id: ENSCAFP00000048409   ⟸   ENSCAFT00000072655
RefSeq Acc Id: XP_038327880   ⟸   XM_038471952
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038327881   ⟸   XM_038471953
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038327879   ⟸   XM_038471951
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038327882   ⟸   XM_038471954
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038327883   ⟸   XM_038471955
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038453139   ⟸   XM_038597211
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038453140   ⟸   XM_038597212
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038453138   ⟸   XM_038597210
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038453141   ⟸   XM_038597213
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038453142   ⟸   XM_038597214
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038517320   ⟸   XM_038661392
- Peptide Label: isoform X2
- UniProtKB: A0A8C0RAG2 (UniProtKB/TrEMBL),   A0A8I3MFB9 (UniProtKB/TrEMBL),   A0A8C0KUW7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038517321   ⟸   XM_038661393
- Peptide Label: isoform X3
- UniProtKB: A0A8I3MT50 (UniProtKB/TrEMBL),   A0A8P0SWG9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038517319   ⟸   XM_038661391
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KUW7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038517322   ⟸   XM_038661394
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038517324   ⟸   XM_038661396
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038331600   ⟸   XM_038475672
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038388814   ⟸   XM_038532886
- Peptide Label: isoform X2
- UniProtKB: A0A8C0KUW7 (UniProtKB/TrEMBL),   A0A8C0RAG2 (UniProtKB/TrEMBL),   A0A8I3MFB9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038388815   ⟸   XM_038532887
- Peptide Label: isoform X3
- UniProtKB: A0A8I3MT50 (UniProtKB/TrEMBL),   A0A8P0SWG9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038388813   ⟸   XM_038532885
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KUW7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038388816   ⟸   XM_038532888
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038388817   ⟸   XM_038532889
- Peptide Label: isoform X4
RefSeq Acc Id: ENSCAFP00845003440   ⟸   ENSCAFT00845004310
RefSeq Acc Id: ENSCAFP00845003429   ⟸   ENSCAFT00845004298
RefSeq Acc Id: ENSCAFP00845003482   ⟸   ENSCAFT00845004360

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000012385 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030001711 UniProtKB/TrEMBL
  ENSCAFG00040002898 UniProtKB/TrEMBL
  ENSCAFG00845002429 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000019677.5 UniProtKB/TrEMBL
  ENSCAFT00000042800.4 UniProtKB/TrEMBL
  ENSCAFT00000072655.2 UniProtKB/TrEMBL
  ENSCAFT00030003064.1 UniProtKB/TrEMBL
  ENSCAFT00040005510.1 UniProtKB/TrEMBL
  ENSCAFT00040005536.1 UniProtKB/TrEMBL
  ENSCAFT00040005572.1 UniProtKB/TrEMBL
  ENSCAFT00845004298 ENTREZGENE
  ENSCAFT00845004298.1 UniProtKB/TrEMBL
  ENSCAFT00845004310 ENTREZGENE
  ENSCAFT00845004310.1 UniProtKB/TrEMBL
  ENSCAFT00845004360.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/TrEMBL
  1.10.150.80 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro BDHCT UniProtKB/TrEMBL
  BDHCT_assoc UniProtKB/TrEMBL
  BLM_N UniProtKB/TrEMBL
  DEAD/DEAH_box_helicase_dom UniProtKB/TrEMBL
  DNA/RNA_helicase_DEAH_CS UniProtKB/TrEMBL
  DNA_helicase_ATP-dep_RecQ UniProtKB/TrEMBL
  Helicase_ATP-bd UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
  HRDC-like_sf UniProtKB/TrEMBL
  HRDC_dom UniProtKB/TrEMBL
  HRDC_dom_sf UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  RecQ_Zn-bd UniProtKB/TrEMBL
  RQC_domain UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
KEGG Report cfa:100685609 UniProtKB/TrEMBL
NCBI Gene BLM ENTREZGENE
PANTHER BLOOM SYNDROME PROTEIN UniProtKB/TrEMBL
  DNA HELICASE RECQ FAMILY MEMBER UniProtKB/TrEMBL
Pfam BDHCT UniProtKB/TrEMBL
  BDHCT_assoc UniProtKB/TrEMBL
  BLM_N UniProtKB/TrEMBL
  DEAD UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
  HRDC UniProtKB/TrEMBL
  RecQ_Zn_bind UniProtKB/TrEMBL
  RQC UniProtKB/TrEMBL
PROSITE DEAH_ATP_HELICASE UniProtKB/TrEMBL
  HELICASE_ATP_BIND_1 UniProtKB/TrEMBL
  HELICASE_CTER UniProtKB/TrEMBL
  HRDC UniProtKB/TrEMBL
SMART DEXDc UniProtKB/TrEMBL
  HELICc UniProtKB/TrEMBL
  HRDC UniProtKB/TrEMBL
  RQC UniProtKB/TrEMBL
Superfamily-SCOP SSF46785 UniProtKB/TrEMBL
  SSF47819 UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt A0A8C0KUW7 ENTREZGENE
  A0A8C0Q0C7_CANLF UniProtKB/TrEMBL
  A0A8C0Q0H9_CANLF UniProtKB/TrEMBL
  A0A8C0Q434_CANLF UniProtKB/TrEMBL
  A0A8C0RAG2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MFB9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MG60_CANLF UniProtKB/TrEMBL
  A0A8I3MT50 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0SWG9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0T1B3_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:57173 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-08-14 BLM  BLM RecQ like helicase    Bloom syndrome RecQ like helicase  Symbol and/or name change 5135510 APPROVED