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Gene: DHRS3 (dehydrogenase/reductase 3) Canis lupus familiaris

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Symbol:

DHRS3

Name:

dehydrogenase/reductase 3

RGD ID:

12183969

Description:

ENCODES a protein that exhibits all-trans-retinol dehydrogenase (NADP+) activity (ortholog); INVOLVED IN bone morphogenesis (ortholog); cardiac septum morphogenesis (ortholog); negative regulation of retinoic acid receptor signaling pathway (ortholog); PARTICIPATES IN retinol metabolic pathway; vitamin A deficiency pathway; ASSOCIATED WITH chromosome 1p36 deletion syndrome (ortholog); Craniosynostosis Syndrome, Autosomal Recessive (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN membrane (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

short-chain dehydrogenase/reductase 3

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	DHRS3 (dehydrogenase/reductase 3)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, PhylomeDB
Mus musculus (house mouse):	Dhrs3 (dehydrogenase/reductase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Dhrs3 (dehydrogenase/reductase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Dhrs3 (dehydrogenase/reductase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	DHRS3 (dehydrogenase/reductase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Dhrs3 (dehydrogenase/reductase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	DHRS3 (dehydrogenase/reductase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	DHRS3 (dehydrogenase/reductase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Dhrs3 (dehydrogenase/reductase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	83,826,361 - 83,865,412 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	83,826,374 - 83,865,426 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	80,360,613 - 80,399,101 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	84,466,959 - 84,505,451 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	84,469,339 - 84,505,448 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	81,237,580 - 81,276,024 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	82,236,372 - 82,274,800 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	83,302,792 - 83,341,302 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

chromosome 1p36 deletion syndrome (ISO)

Craniosynostosis Syndrome, Autosomal Recessive (ISO)

Experimental Liver Cirrhosis (ISO)

nonprogressive cerebellar ataxia with mental retardation (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

bone morphogenesis (IEA,ISO)

cardiac septum morphogenesis (IEA,ISO)

negative regulation of retinoic acid receptor signaling pathway (IEA,ISO)

outflow tract morphogenesis (IEA,ISO)

regulation of ossification (IEA,ISO)

retinoid metabolic process (IEA,ISO)

roof of mouth development (IEA,ISO)

Cellular Component

membrane (IEA)

Molecular Function

all-trans-retinol dehydrogenase (NAD+) activity (IEA)

all-trans-retinol dehydrogenase (NADP+) activity (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

retinol metabolic pathway (ISO)

vitamin A deficiency pathway (ISO)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

DHRS3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	83,826,361 - 83,865,412 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	83,826,374 - 83,865,426 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	80,360,613 - 80,399,101 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	84,466,959 - 84,505,451 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	84,469,339 - 84,505,448 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	81,237,580 - 81,276,024 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	82,236,372 - 82,274,800 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	83,302,792 - 83,341,302 (+)	NCBI		UU_Cfam_GSD_1.0

DHRS3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	12,567,910 - 12,618,210 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	12,567,909 - 12,620,133 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	12,627,939 - 12,678,216 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	12,550,526 - 12,600,407 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	12,562,205 - 12,611,734	NCBI
Celera	1	11,739,647 - 11,790,328 (-)	NCBI		Celera
Cytogenetic Map	1	p36.21	NCBI
HuRef	1	11,780,861 - 11,830,631 (-)	NCBI		HuRef
CHM1_1	1	12,615,961 - 12,665,873 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	12,112,042 - 12,164,110 (-)	NCBI		T2T-CHM13v2.0

Dhrs3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	144,618,712 - 144,654,214 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	144,619,397 - 144,654,779 (+)	Ensembl		GRCm39 Ensembl
GRCm38	4	144,892,534 - 144,928,209 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	144,892,827 - 144,928,209 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	144,482,730 - 144,517,548 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	144,159,764 - 144,194,896 (+)	NCBI		MGSCv36	mm8
Celera	4	146,478,723 - 146,513,572 (+)	NCBI		Celera
Cytogenetic Map	4	E1	NCBI
cM Map	4	78.14	NCBI

Dhrs3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	162,031,853 - 162,065,655 (+)	NCBI		GRCr8
mRatBN7.2	5	156,747,939 - 156,782,420 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	156,747,962 - 156,782,417 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	159,442,883 - 159,476,659 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	161,216,178 - 161,249,955 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	161,172,504 - 161,206,285 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	162,809,090 - 162,843,385 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	162,808,646 - 162,843,383 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	166,490,669 - 166,524,735 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	163,341,856 - 163,375,604 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	163,351,897 - 163,386,360 (+)	NCBI
Celera	5	155,037,838 - 155,072,177 (+)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

Dhrs3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955486	1,439,179 - 1,474,130 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955486	1,439,179 - 1,473,476 (+)	NCBI	ChiLan1.0	ChiLan1.0

DHRS3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	215,613,024 - 215,666,906 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	214,262,703 - 214,313,799 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	11,319,109 - 11,370,463 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	12,533,696 - 12,584,381 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	12,533,696 - 12,584,381 (-)	Ensembl	panpan1.1		panPan2

Dhrs3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	35,412,395 - 35,445,492 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936474	1,235,962 - 1,269,510 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936474	1,237,177 - 1,270,299 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

DHRS3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	72,556,236 - 72,598,815 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	72,556,234 - 72,599,233 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	66,685,233 - 66,695,568 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

DHRS3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	119,183,453 - 119,236,953 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	119,184,996 - 119,237,015 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666054	22,986,171 - 23,040,105 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Dhrs3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624818	557,409 - 590,872 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624818	557,399 - 590,872 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in DHRS3
864 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	reproductive system	respiratory system
6	5	5	23	22	16	6	6	6	6	33	22	12	14	10

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_022414496	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022414497	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022414498	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038464536	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038464541	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038471078	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038471079	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038471081	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038471082	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038531962	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038531963	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038531964	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038531965	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038596231	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038596232	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038596233	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038596234	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038660306	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038660307	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038660309	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038660310	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_544561	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000035	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000045	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000373	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00000025970 ⟹ ENSCAFP00000024108

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	2	83,828,501 - 83,865,426 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00000071094 ⟹ ENSCAFP00000053587

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	2	83,826,374 - 83,865,426 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00000085531 ⟹ ENSCAFP00000064971

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	2	83,826,374 - 83,865,426 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845002276 ⟹ ENSCAFP00845001802

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	2	84,469,339 - 84,505,448 (+)	Ensembl

RefSeq Acc Id:

XM_022414496 ⟹ XP_022270204

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	2	83,826,361 - 83,865,412 (+)	NCBI
Dog10K_Boxer_Tasha	2	80,360,613 - 80,399,101 (+)	NCBI

Sequence:

show sequence

CCGAGGATAACAGATGACAGATGACAACAGGCTGCGGGCGTTCCCGCTCCAGGCTCCCCGGCTC
CGGAGCAGGCCCGCGGACACCAGGCGCGGCTGGGACCAAGGGGCCGGGCTCTCTCAGATTGTTC
TCTGGGGCCGGACTGAGAAATGCCTGAAGGAGACGACGGAGGAGATTCGGCAGATGGGCACCGA
GTGCCACTACTTCATCTGTGACGTGGGCAACCGGGAGGAGGTGTACCAGACGGCCAAAGCCGTC
CGGGAGAAGGTGGGCGACATCACCATCCTGGTGAACAACGCGGCCGTGGTCCACGGGAAGAGCC
TGATGGACAGTGACGACGATGCCCTCCTCAAGTCCCAGCACATCAACACACTGGGCCAGTTCTG
GACCACCAAGGCCTTCCTGCCCCGCATGCTGGAGCTGCAGAACGGCCACATCGTGTGTCTCAAC
TCCGTGCTGGCGCTCTCTGCCATCCCCGGTGCCATCGACTACTGCACGTCCAAAGCCTCGGCCT
TCGCCTTCATGGAGAGCCTGACCCTGGGGCTGCTGGACTGCCCAGGAGTCAGCGCCACCACCGT
GCTGCCCTTCCACACCAGCACCGAGATGTTCCAGGGCATGAGGGTCAGGTTCCCCAACCTCTTC
CCGCCGCTGAAGCCGGAGACGGTGGCGCGGAGGACGGTGGAAGCCGTGCAGCTCAATCAAGCCC
TGCTCCTCCTCCCGTGGACCATGCACGCCCTCATTATCTTGAAAAGCATCCTCCCACAGGCCGC
GCTGGAGGAGATCCACAGATTCTCAGGAACCTACACCTGCATGAACACTTTCAAAGGGCGGACA
TAAAGGCGGGACGCGGACACGCGCTCGGGAGCCCGGGAGCCGAGGGGCCGAGGTCCTGGCACGC
ACCCACCGCCTGCCCCTTGCACAGCCCTGCTGGGTGAACGGGACTGCTGCCGGCGCCAGGAAGA
ATCCGGGTGCCCCCGGGCCGGCCCCAGGACCTCCGCACGGACTGACGGCGTGACTCCGGCCCCC
ACGGGAGGCGGGACACCAGCCAGCAGCCACCTTGACACTTTCACTTGTTTCTAATTCTGTAGAG
TTTATTGTCGAGTCGCTTCTCAGTCTAACCGGCCTTAGCAGCGCGCACGGACTGCTCCAGGAGG
CTCCGCACCTGCCCAGACGCTTTTTCCTTCCAAAATCCACCCGTCCTCGGCTTGCGCAAACTGG
TTGAATGGCAGGAATGAAAAATAAAGAGACGGTTTTGCGAG

hide sequence

RefSeq Acc Id:

XM_038464536 ⟹ XP_038320464

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	2	80,361,575 - 80,399,101 (+)	NCBI

RefSeq Acc Id:

XM_038464541 ⟹ XP_038320469

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	2	80,379,441 - 80,399,101 (+)	NCBI

RefSeq Acc Id:

XM_038471078 ⟹ XP_038327006

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	2	81,239,940 - 81,276,024 (+)	NCBI

RefSeq Acc Id:

XM_038471079 ⟹ XP_038327007

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	2	81,237,580 - 81,276,024 (+)	NCBI

RefSeq Acc Id:

XM_038471081 ⟹ XP_038327009

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	2	81,238,539 - 81,276,024 (+)	NCBI

RefSeq Acc Id:

XM_038471082 ⟹ XP_038327010

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	2	81,256,405 - 81,276,024 (+)	NCBI

RefSeq Acc Id:

XM_038531962 ⟹ XP_038387890

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	2	83,305,149 - 83,341,302 (+)	NCBI

RefSeq Acc Id:

XM_038531963 ⟹ XP_038387891

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	2	83,302,792 - 83,341,302 (+)	NCBI

RefSeq Acc Id:

XM_038531964 ⟹ XP_038387892

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	2	83,303,761 - 83,341,302 (+)	NCBI

RefSeq Acc Id:

XM_038531965 ⟹ XP_038387893

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	2	83,321,629 - 83,341,302 (+)	NCBI

RefSeq Acc Id:

XM_038596231 ⟹ XP_038452159

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	2	82,238,697 - 82,274,800 (+)	NCBI

RefSeq Acc Id:

XM_038596232 ⟹ XP_038452160

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	2	82,236,372 - 82,274,800 (+)	NCBI

RefSeq Acc Id:

XM_038596233 ⟹ XP_038452161

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	2	82,237,319 - 82,274,800 (+)	NCBI

RefSeq Acc Id:

XM_038596234 ⟹ XP_038452162

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	2	82,255,162 - 82,274,800 (+)	NCBI

RefSeq Acc Id:

XM_038660306 ⟹ XP_038516234

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	2	84,469,328 - 84,505,451 (+)	NCBI

RefSeq Acc Id:

XM_038660307 ⟹ XP_038516235

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	2	84,466,959 - 84,505,451 (+)	NCBI

RefSeq Acc Id:

XM_038660309 ⟹ XP_038516237

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	2	84,467,934 - 84,505,451 (+)	NCBI

RefSeq Acc Id:

XM_038660310 ⟹ XP_038516238

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	2	84,485,792 - 84,505,451 (+)	NCBI

RefSeq Acc Id:

XM_544561 ⟹ XP_544561

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	2	83,828,889 - 83,865,412 (+)	NCBI
Dog10K_Boxer_Tasha	2	80,362,979 - 80,399,101 (+)	NCBI

Sequence:

show sequence

CACCCCCGCCGCTGCCTAAACTCCTCTGCGAGCCTGTAAACATTTACCTGCGAATTCCCCAGCC
CCGGCGGCTGCTGGGGCAAGAGGCTTCTTGTTAGAACTTTCCACCTCCGGCTTCCCCTCCAGCC
CTCTCTGGCTGTCCCGACCTCCGCAGACGCTTTTGCTCCTCCCGAGCAGAATTTATCCTTGTTT
TGTTTTGTTTTGTTTTTCTTCTTTTTTTTTTTCTTTTTTTTTTTTTTAACCCTCACCCCCTGTG
TTTTGCATTTGGGGAGGGGAGGAAGAGGTGGTTTCCAAGAGTGACCAAGGTGGGACGCCTCTCC
GACCCTTAATTTGGGTTATTTATTATTATTGTTTGCGGTGTTTTCTTTTTTCTTTTTTTTTTTT
TTTTTTTGATTGCTGTGTTGCTGGTCCGGGGAGTTCCGCCGCGCCCCCTCCCCTGCGCCCTCAC
CCCCACCCCTCCCCGCCCCCCCGGCCCGGCTCCGCGGCGCGGAGGATGGTGTGGAAATGGCTGG
GCGCGTTGGTGGGGTTCCCTCTGCAGATCATCTACCTGGTGGCCAAAGCCGCCGTGGGGCTGGT
GCTGCCCGCCAAGCTGCGGGACCTGTCACGGGAGAACGTGCTCATCACCGGCGGCGGGAGAGGC
ATCGGGCGCCAGCTCGCCCGCGAGTTCGCAGAACGCGGCGCCAGGAAGATTGTTCTCTGGGGCC
GGACTGAGAAATGCCTGAAGGAGACGACGGAGGAGATTCGGCAGATGGGCACCGAGTGCCACTA
CTTCATCTGTGACGTGGGCAACCGGGAGGAGGTGTACCAGACGGCCAAAGCCGTCCGGGAGAAG
GTGGGCGACATCACCATCCTGGTGAACAACGCGGCCGTGGTCCACGGGAAGAGCCTGATGGACA
GTGACGACGATGCCCTCCTCAAGTCCCAGCACATCAACACACTGGGCCAGTTCTGGACCACCAA
GGCCTTCCTGCCCCGCATGCTGGAGCTGCAGAACGGCCACATCGTGTGTCTCAACTCCGTGCTG
GCGCTCTCTGCCATCCCCGGTGCCATCGACTACTGCACGTCCAAAGCCTCGGCCTTCGCCTTCA
TGGAGAGCCTGACCCTGGGGCTGCTGGACTGCCCAGGAGTCAGCGCCACCACCGTGCTGCCCTT
CCACACCAGCACCGAGATGTTCCAGGGCATGAGGGTCAGGTTCCCCAACCTCTTCCCGCCGCTG
AAGCCGGAGACGGTGGCGCGGAGGACGGTGGAAGCCGTGCAGCTCAATCAAGCCCTGCTCCTCC
TCCCGTGGACCATGCACGCCCTCATTATCTTGAAAAGCATCCTCCCACAGGCCGCGCTGGAGGA
GATCCACAGATTCTCAGGAACCTACACCTGCATGAACACTTTCAAAGGGCGGACATAAAGGCGG
GACGCGGACACGCGCTCGGGAGCCCGGGAGCCGAGGGGCCGAGGTCCTGGCACGCACCCACCGC
CTGCCCCTTGCACAGCCCTGCTGGGTGAACGGGACTGCTGCCGGCGCCAGGAAGAATCCGGGTG
CCCCCGGGCCGGCCCCAGGACCTCCGCACGGACTGACGGCGTGACTCCGGCCCCCACGGGAGGC
GGGACACCAGCCAGCAGCCACCTTGACACTTTCACTTGTTTCTAATTCTGTAGAGTTTATTGTC
GAGTCGCTTCTCAGTCTAACCGGCCTTAGCAGCGCGCACGGACTGCTCCAGGAGGCTCCGCACC
TGCCCAGACGCTTTTTCCTTCCAAAATCCACCCGTCCTCGGCTTGCGCAAACTGGTTGAATGGC
AGGAATGAAAAATAAAGAGACGGTTTTGCGAG

hide sequence

Protein Sequences


Protein RefSeqs	XP_022270204	(Get FASTA)	NCBI Sequence Viewer
	XP_038320464	(Get FASTA)	NCBI Sequence Viewer
	XP_038320469	(Get FASTA)	NCBI Sequence Viewer
	XP_038327006	(Get FASTA)	NCBI Sequence Viewer
	XP_038327007	(Get FASTA)	NCBI Sequence Viewer
	XP_038327009	(Get FASTA)	NCBI Sequence Viewer
	XP_038327010	(Get FASTA)	NCBI Sequence Viewer
	XP_038387890	(Get FASTA)	NCBI Sequence Viewer
	XP_038387891	(Get FASTA)	NCBI Sequence Viewer
	XP_038387892	(Get FASTA)	NCBI Sequence Viewer
	XP_038387893	(Get FASTA)	NCBI Sequence Viewer
	XP_038452159	(Get FASTA)	NCBI Sequence Viewer
	XP_038452160	(Get FASTA)	NCBI Sequence Viewer
	XP_038452161	(Get FASTA)	NCBI Sequence Viewer
	XP_038452162	(Get FASTA)	NCBI Sequence Viewer
	XP_038516234	(Get FASTA)	NCBI Sequence Viewer
	XP_038516235	(Get FASTA)	NCBI Sequence Viewer
	XP_038516237	(Get FASTA)	NCBI Sequence Viewer
	XP_038516238	(Get FASTA)	NCBI Sequence Viewer
	XP_544561	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000053587.2
	ENSCAFP00030011706.1
	ENSCAFP00030011768.1
	ENSCAFP00040007629.1
	ENSCAFP00040007670.1
	ENSCAFP00845001802
	ENSCAFP00845001802.1

RefSeq Acc Id:	XP_544561 ⟸ XM_544561
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0JWX6 (UniProtKB/TrEMBL), A0A8C0MHF6 (UniProtKB/TrEMBL), A0A8I3MI27 (UniProtKB/TrEMBL), A0A8C0REM4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MVWKWLGALVGFPLQIIYLVAKAAVGLVLPAKLRDLSRENVLITGGGRGIGRQLAREFAERGAR KIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNREEVYQTAKAVREKVGDITILVNNAAVVH GKSLMDSDDDALLKSQHINTLGQFWTTKAFLPRMLELQNGHIVCLNSVLALSAIPGAIDYCTSK ASAFAFMESLTLGLLDCPGVSATTVLPFHTSTEMFQGMRVRFPNLFPPLKPETVARRTVEAVQL NQALLLLPWTMHALIILKSILPQAALEEIHRFSGTYTCMNTFKGRT hide sequence

RefSeq Acc Id:

XP_022270204 ⟸ XM_022414496

- Peptide Label:

isoform X2

- Sequence:

show sequence

MTDDNRLRAFPLQAPRLRSRPADTRRGWDQGAGLSQIVLWGRTEKCLKETTEEIRQMGTECHYF
ICDVGNREEVYQTAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKA
FLPRMLELQNGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSATTVLPFH
TSTEMFQGMRVRFPNLFPPLKPETVARRTVEAVQLNQALLLLPWTMHALIILKSILPQAALEEI
HRFSGTYTCMNTFKGRT

hide sequence

Ensembl Acc Id:

ENSCAFP00000024108 ⟸ ENSCAFT00000025970

Ensembl Acc Id:

ENSCAFP00000053587 ⟸ ENSCAFT00000071094

Ensembl Acc Id:

ENSCAFP00000064971 ⟸ ENSCAFT00000085531

RefSeq Acc Id:	XP_038327007 ⟸ XM_038471079
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038327009 ⟸ XM_038471081
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038327006 ⟸ XM_038471078
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038327010 ⟸ XM_038471082
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038452160 ⟸ XM_038596232
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038452161 ⟸ XM_038596233
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038452159 ⟸ XM_038596231
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038452162 ⟸ XM_038596234
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038516235 ⟸ XM_038660307
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038516237 ⟸ XM_038660309
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038516234 ⟸ XM_038660306
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0JWX6 (UniProtKB/TrEMBL), A0A8C0MHF6 (UniProtKB/TrEMBL), A0A8I3MI27 (UniProtKB/TrEMBL), A0A8C0REM4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038516238 ⟸ XM_038660310
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038320464 ⟸ XM_038464536
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038320469 ⟸ XM_038464541
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038387891 ⟸ XM_038531963
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038387892 ⟸ XM_038531964
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038387890 ⟸ XM_038531962
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0JWX6 (UniProtKB/TrEMBL), A0A8C0MHF6 (UniProtKB/TrEMBL), A0A8C0REM4 (UniProtKB/TrEMBL), A0A8I3MI27 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038387893 ⟸ XM_038531965
- Peptide Label:	isoform X2

Ensembl Acc Id:

ENSCAFP00845001802 ⟸ ENSCAFT00845002276

Promoters

RGD ID:

13682650

Promoter ID:

EPDNEW_C717

Type:

initiation region

Name:

DHRS3_1

Description:

dehydrogenase/reductase 3

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_C718

Experiment Methods:

Single-end sequencing.

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	2	83,828,934 - 83,828,994	EPDNEW

RGD ID:

13682651

Promoter ID:

EPDNEW_C718

Type:

single initiation site

Name:

DHRS3_2

Description:

dehydrogenase/reductase 3

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_C717

Experiment Methods:

Single-end sequencing.

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	2	83,829,281 - 83,829,341	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000016376	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030007275	UniProtKB/TrEMBL
	ENSCAFG00040004645	UniProtKB/TrEMBL
	ENSCAFG00845001328	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000071094.2	UniProtKB/TrEMBL
	ENSCAFT00030013405.1	UniProtKB/TrEMBL
	ENSCAFT00030013475.1	UniProtKB/TrEMBL
	ENSCAFT00040008781.1	UniProtKB/TrEMBL
	ENSCAFT00040008831.1	UniProtKB/TrEMBL
	ENSCAFT00845002276	ENTREZGENE
	ENSCAFT00845002276.1	UniProtKB/TrEMBL
Gene3D-CATH	NAD(P)-binding Rossmann-like Domain	UniProtKB/TrEMBL
InterPro	NAD(P)-bd_dom_sf	UniProtKB/TrEMBL
	SDR_fam	UniProtKB/TrEMBL
NCBI Gene	DHRS3	ENTREZGENE
PANTHER	PKSB	UniProtKB/TrEMBL
	PTHR24322:SF483	UniProtKB/TrEMBL
Pfam	adh_short	UniProtKB/TrEMBL
PRINTS	GDHRDH	UniProtKB/TrEMBL
	SDRFAMILY	UniProtKB/TrEMBL
SMART	PKS_KR	UniProtKB/TrEMBL
Superfamily-SCOP	SSF51735	UniProtKB/TrEMBL
UniProt	A0A8C0JWX6	ENTREZGENE
	A0A8C0MHF6	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0REM4	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0RY22_CANLF	UniProtKB/TrEMBL
	A0A8I3MI27	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:39934	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Annotations - SMPDB

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Annotations - SMPDB